PT1023291E - Derivados de dipiridoimidazole uteis no tratamento de desordens do sistema nervoso central - Google Patents

Derivados de dipiridoimidazole uteis no tratamento de desordens do sistema nervoso central

Info

Publication number
PT1023291E
PT1023291E PT98953243T PT98953243T PT1023291E PT 1023291 E PT1023291 E PT 1023291E PT 98953243 T PT98953243 T PT 98953243T PT 98953243 T PT98953243 T PT 98953243T PT 1023291 E PT1023291 E PT 1023291E
Authority
PT
Portugal
Prior art keywords
derivatives
dipiridoimidazole
disorders
treatment
nervous system
Prior art date
Application number
PT98953243T
Other languages
English (en)
Inventor
Allen B Reitz
Bruce E Maryanoff
David Mccomsey
James Mcnally
Samuel O Nortey
Original Assignee
Ortho Mcneil Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Mcneil Pharm Inc filed Critical Ortho Mcneil Pharm Inc
Publication of PT1023291E publication Critical patent/PT1023291E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PT98953243T 1997-10-07 1998-10-05 Derivados de dipiridoimidazole uteis no tratamento de desordens do sistema nervoso central PT1023291E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6124897P 1997-10-07 1997-10-07

Publications (1)

Publication Number Publication Date
PT1023291E true PT1023291E (pt) 2004-09-30

Family

ID=22034585

Family Applications (1)

Application Number Title Priority Date Filing Date
PT98953243T PT1023291E (pt) 1997-10-07 1998-10-05 Derivados de dipiridoimidazole uteis no tratamento de desordens do sistema nervoso central

Country Status (11)

Country Link
US (1) US5968946A (pt)
EP (1) EP1023291B1 (pt)
JP (1) JP2001519351A (pt)
AT (1) ATE267828T1 (pt)
AU (1) AU1066499A (pt)
CA (1) CA2305342A1 (pt)
DE (1) DE69824195T2 (pt)
DK (1) DK1023291T3 (pt)
ES (1) ES2221996T3 (pt)
PT (1) PT1023291E (pt)
WO (1) WO1999018105A1 (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001009132A1 (en) 1999-08-02 2001-02-08 Ortho-Mcneil Pharmaceutical, Inc. C-6 RING-SUBSTITUTED PYRIDO[1,2-a]BENZIMIDAZOLE DERIVATIVES USEFUL IN TREATING CENTRAL NERVOUS SYSTEM DISORDERS
WO2001092257A1 (en) * 2000-05-26 2001-12-06 Neurogen Corporation Oxo-imidazopyrimidine-carboxamides and their use as gaba brain receptor ligands
AU2004278014B2 (en) 2003-10-03 2011-04-28 3M Innovative Properties Company Alkoxy substituted imidazoquinolines
WO2005046683A1 (en) * 2003-10-07 2005-05-26 Renovis, Inc. Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same
WO2005051317A2 (en) 2003-11-25 2005-06-09 3M Innovative Properties Company Substituted imidazo ring systems and methods
AU2004312510A1 (en) * 2003-12-29 2005-07-21 3M Innovative Properties Company Piperazine, [1,4]diazepane, [1,4]diazocane, and [1,5]diazocane fused imidazo ring compounds
JP2008530022A (ja) 2005-02-04 2008-08-07 コーリー ファーマシューティカル グループ，インコーポレイテッド 免疫反応調節物質を含む水性ゲル処方物
JP2008531690A (ja) * 2005-02-28 2008-08-14 レノビス， インコーポレイテッド イオンチャネルリガンドとしてのアミド誘導体並びにそれを使用する医薬組成物及び方法
US7576099B2 (en) * 2005-02-28 2009-08-18 Renovis, Inc. Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same
EP2124562B1 (en) * 2007-03-09 2016-04-20 Second Genome, Inc. Bicycloheteroaryl compounds as p2x7 modulators and uses thereof
EP3553051A4 (en) * 2016-12-06 2020-04-22 Nippon Kayaku Kabushiki Kaisha METHOD FOR PRODUCING 3- (PYRIDYL-2-AMINO) PROPIONITRILE AND ANALOGUE THEREOF

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100262762B1 (ko) * 1992-08-19 2000-08-01 랄프 알. 팔로 중추신경계 질환의 치료에 유용한 3-옥소-피리도(1,2-알파)벤즈이미다졸-4-카복실 및 4-옥소-아제디노(1,2-알파)벤즈이미다졸-5-카복실 유도체
ES2212081T3 (es) * 1996-10-07 2004-07-16 Ortho-Mcneil Pharmaceutical, Inc. Derivados de 3-oxo-pirido(1,2-a)bencimidazol-4-carboxamida que contienen 5-heteroatomos sustituidos con alquilo en el tratamiento de trastornos del sistema nervioso central.

Also Published As

Publication number Publication date
EP1023291A1 (en) 2000-08-02
WO1999018105A1 (en) 1999-04-15
ES2221996T3 (es) 2005-01-16
DK1023291T3 (da) 2004-10-04
WO1999018105A8 (en) 1999-06-10
ATE267828T1 (de) 2004-06-15
DE69824195T2 (de) 2005-06-23
JP2001519351A (ja) 2001-10-23
DE69824195D1 (de) 2004-07-01
US5968946A (en) 1999-10-19
EP1023291B1 (en) 2004-05-26
AU1066499A (en) 1999-04-27
CA2305342A1 (en) 1999-04-15

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