TR199600779A2 - Imidazo benzodiazepin türevlerinin imal edilmesine mahsus yöntem. - Google Patents

Imidazo benzodiazepin türevlerinin imal edilmesine mahsus yöntem.

Info

Publication number
TR199600779A2
TR199600779A2 TR96/00779A TR9600779A TR199600779A2 TR 199600779 A2 TR199600779 A2 TR 199600779A2 TR 96/00779 A TR96/00779 A TR 96/00779A TR 9600779 A TR9600779 A TR 9600779A TR 199600779 A2 TR199600779 A2 TR 199600779A2
Authority
TR
Turkey
Prior art keywords
production
benzodiazepine derivatives
imidazo
imidazo benzodiazepine
derivatives
Prior art date
Application number
TR96/00779A
Other languages
English (en)
Inventor
Karl-Heinz Bender
Manfred Breuninger
Manfred Froom
Siegfried Schmitt
Kurt Steiner
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of TR199600779A2 publication Critical patent/TR199600779A2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
TR96/00779A 1995-10-10 1996-09-30 Imidazo benzodiazepin türevlerinin imal edilmesine mahsus yöntem. TR199600779A2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH285495 1995-10-10

Publications (1)

Publication Number Publication Date
TR199600779A2 true TR199600779A2 (tr) 1997-04-22

Family

ID=4243076

Family Applications (1)

Application Number Title Priority Date Filing Date
TR96/00779A TR199600779A2 (tr) 1995-10-10 1996-09-30 Imidazo benzodiazepin türevlerinin imal edilmesine mahsus yöntem.

Country Status (14)

Country Link
US (1) US5693795A (tr)
EP (1) EP0768310B1 (tr)
JP (1) JP3007050B2 (tr)
CN (1) CN1060776C (tr)
AR (1) AR003800A1 (tr)
AT (1) ATE187727T1 (tr)
BR (1) BR9605030A (tr)
CA (1) CA2184802C (tr)
DE (1) DE59603916D1 (tr)
DK (1) DK0768310T3 (tr)
ES (1) ES2141428T3 (tr)
GR (1) GR3032600T3 (tr)
MX (1) MX9604687A (tr)
TR (1) TR199600779A2 (tr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6512114B1 (en) * 1999-06-30 2003-01-28 Abbott Laboratories Process for the preparation of Midazolam
US6262260B1 (en) * 2000-03-23 2001-07-17 Abbott Laboratories Process for the preparation of midazolam
JP4298212B2 (ja) * 2002-03-29 2009-07-15 大日本印刷株式会社 塩酸エピナスチン高融点型結晶の製造法
BRPI0907103A2 (pt) * 2008-02-08 2016-05-03 Colgate Palmolive Co método para tratamento de dentes sensíveis, composição de selante dental, e, uso de um aminoácido básico em forma livre ou em forma de sal.
CN102215811A (zh) * 2008-02-08 2011-10-12 高露洁-棕榄公司 泡腾组合物
WO2009100279A2 (en) * 2008-02-08 2009-08-13 Colgate-Palmolive Company Compositions comprising basic amino acid and soluble carbonate salt
CA2705606C (en) * 2008-02-08 2014-07-08 Colgate-Palmolive Company Compositions and methods comprising basic amino acid peptides and proteases
CN101938984A (zh) * 2008-02-08 2011-01-05 高露洁-棕榄公司 清洁用组合物和方法
BRPI0907108A2 (pt) * 2008-02-08 2016-07-26 Colgate Palmolive Co escova de dentes.
AU2009212333C1 (en) * 2008-02-08 2012-07-19 Colgate-Palmolive Company Compositions and devices
BRPI0906452A2 (pt) * 2008-02-08 2015-07-14 Colgate Palmolive Co Composição, dispositivo, método para produzir ou inibir a formação de cáries dentais, reduzir, reparar ou inibir as leões pré-cárie do esmalte, reduzir ou inibir a desmineralização e promover a remineralização dos dentes, reduzir a hipersensibilidade dos dentes, reduzir ou inibir a gengivite, promover a cura de feridas ou de cortes na boca, reduzir os níveis de bactérias que produzem ácido, aumentar os níveis relativos de bactérias arginolíticas, inibir a formação de composição, dispositivo, método para reduzir ou inibir a formação de cáries dentais, reduzir, reparar ou inibir as leões pré-cárie dp esmalte, reduzir ou inibir a desmineralização e promover a remineralização dos dentes, reduzir a hipersibilidade dos dentes, reduzir ou inibir a gengivite, promover a cura de feridas ou de cortes na boca, reduzir os níveis de bactérias que produzem ácido, aumentar os níveis relativos de bactérias arginolíticas, inibir a formação de biofilme microbiano na cavidade oral, elevar e/ou manter o ph da placa em níveis de pelos menos um ph de 5,5, reduzir o acúmulo de placa, tratar, aliviar ou reduzir a boca seca, limpar os dentes e a cavidade oral, reduzir a erosão, branquear os dentes, imunizar os dentes contra as bactérias cariogênicas, e/ ou promover a saúde sistêmica, incluindo a saúde cardiovascular, e, uso de um aminoácido básico
MX2010005190A (es) 2008-02-08 2010-06-03 Colgate Palmolive Co Hilo dental.
JP2011511793A (ja) * 2008-02-08 2011-04-14 コルゲート・パーモリブ・カンパニー 口内乾燥の処置のための組成物および方法
IT1399764B1 (it) * 2010-05-04 2013-05-03 F S I Fabbrica Italiana Sint Procedimento per la sintesi di 4h-imidazo [1,5-a][1,4]benzodiazepine, in particolare di midazolam.
UA110640C2 (uk) * 2011-05-05 2016-01-25 Янссен Фармацевтика Нв ПРОТИГРИБКОВІ 5,6-ДИГІДРО-4Н-ПІРОЛО[1,2-a][1,4]БЕНЗОДІАЗЕПІНИ ТА 6Н-ПІРОЛО[1,2-a][1,4]БЕНЗОДІАЗЕПІНИ, ЯКІ ЗАМІЩЕНІ ГЕТЕРОЦИКЛІЧНИМИ ПОХІДНИМИ
BR112019003065A2 (pt) 2016-08-16 2019-05-21 The Trustees Of Columbia University In The City Of New York moduladores do receptor gaba(a) e métodos para o controle da hiper-responsividade das vias respiratórias e inflamação na asma
CN113603635B (zh) * 2021-10-08 2021-12-24 湖南速博生物技术有限公司 一种芳香族二元羧酸酯水解脱羧的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4280957A (en) * 1974-09-11 1981-07-28 Hoffmann-La Roche Inc. Imidazodiazepines and processes therefor
US4307237A (en) * 1974-09-11 1981-12-22 Hoffmann-La Roche Inc. Imidazoles
AT361486B (de) * 1975-08-07 1981-03-10 Hoffmann La Roche Verfahren zur herstellung von neuen imidazo(1,5 -a) (1,4)diazepinverbindungen, ihren salzen und optisch aktiven formen

Also Published As

Publication number Publication date
JPH09110871A (ja) 1997-04-28
US5693795A (en) 1997-12-02
CN1150152A (zh) 1997-05-21
EP0768310A1 (de) 1997-04-16
CA2184802C (en) 2007-07-31
JP3007050B2 (ja) 2000-02-07
ES2141428T3 (es) 2000-03-16
CA2184802A1 (en) 1997-04-11
MX9604687A (es) 1997-04-30
AR003800A1 (es) 1998-09-09
BR9605030A (pt) 1998-06-30
EP0768310B1 (de) 1999-12-15
DE59603916D1 (de) 2000-01-20
ATE187727T1 (de) 2000-01-15
CN1060776C (zh) 2001-01-17
GR3032600T3 (en) 2000-05-31
DK0768310T3 (da) 2000-04-17

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