NO973835L - Fremgangsmåte for fremstilling av lorakarbefmonohydrat - Google Patents
Fremgangsmåte for fremstilling av lorakarbefmonohydratInfo
- Publication number
- NO973835L NO973835L NO973835A NO973835A NO973835L NO 973835 L NO973835 L NO 973835L NO 973835 A NO973835 A NO 973835A NO 973835 A NO973835 A NO 973835A NO 973835 L NO973835 L NO 973835L
- Authority
- NO
- Norway
- Prior art keywords
- preparation
- loracarbef monohydrate
- loracarbef
- monohydrate
- Prior art date
Links
- GPYKKBAAPVOCIW-HSASPSRMSA-N (6r,7s)-7-[[(2r)-2-amino-2-phenylacetyl]amino]-3-chloro-8-oxo-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydrate Chemical compound O.C1([C@H](C(=O)N[C@@H]2C(N3C(=C(Cl)CC[C@@H]32)C(O)=O)=O)N)=CC=CC=C1 GPYKKBAAPVOCIW-HSASPSRMSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
- C07D463/16—Nitrogen atoms
- C07D463/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
- C07D463/20—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D463/22—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/396,948 US5580977A (en) | 1995-03-01 | 1995-03-01 | Process for preparing loracarbef monohydrate |
| PCT/US1996/002586 WO1996026942A1 (en) | 1995-03-01 | 1996-02-28 | A process for preparing loracarbef monohydrate |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO973835D0 NO973835D0 (no) | 1997-08-20 |
| NO973835L true NO973835L (no) | 1997-08-20 |
| NO308471B1 NO308471B1 (no) | 2000-09-18 |
Family
ID=23569249
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO973835A NO308471B1 (no) | 1995-03-01 | 1997-08-20 | FremgangsmÕter for fremstilling av lorakarbefmonohydrat og krystallinsk anhydratform av lorakarbef |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US5580977A (no) |
| EP (1) | EP0729959B1 (no) |
| JP (1) | JPH11501032A (no) |
| KR (1) | KR19980702666A (no) |
| CN (1) | CN1061349C (no) |
| AR (1) | AR002709A1 (no) |
| AT (1) | ATE184006T1 (no) |
| AU (1) | AU694639B2 (no) |
| BR (1) | BR9607308A (no) |
| CA (1) | CA2213812A1 (no) |
| CO (1) | CO4700429A1 (no) |
| CZ (1) | CZ272897A3 (no) |
| DE (1) | DE69603995T2 (no) |
| DK (1) | DK0729959T3 (no) |
| ES (1) | ES2135165T3 (no) |
| GR (1) | GR3031947T3 (no) |
| HU (1) | HUP9702151A3 (no) |
| IL (1) | IL117228A (no) |
| NO (1) | NO308471B1 (no) |
| NZ (1) | NZ304534A (no) |
| PE (1) | PE28097A1 (no) |
| PL (1) | PL322111A1 (no) |
| RU (1) | RU2160261C2 (no) |
| SI (1) | SI0729959T1 (no) |
| TR (1) | TR199700877T1 (no) |
| TW (1) | TW330205B (no) |
| WO (1) | WO1996026942A1 (no) |
| ZA (1) | ZA961341B (no) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999024432A1 (fr) | 1997-11-12 | 1999-05-20 | Mitsubishi Chemical Corporation | Derives de purine et medicament les renfermant en tant qu'ingredient actif |
| WO2000068231A1 (en) | 1999-05-11 | 2000-11-16 | Mitsubishi Chemical Corporation | Purine derivative dihydrate, drugs containing the same as the active ingredient and intermediate in the production thereof |
| PE20011061A1 (es) | 2000-02-01 | 2001-11-20 | Procter & Gamble | Cristalizacion selectiva del acido 3-piridil-1-hidroxi-etiliden-1,1-bisfosfonico sodio como el hemipentahidrato o el monohidrato |
| US6562974B2 (en) | 2000-02-01 | 2003-05-13 | The Procter & Gamble Company | Process for making geminal bisphosphonates |
| CA2506872A1 (en) * | 2002-11-21 | 2004-06-03 | Ranbaxy Laboratories Limited | Monohydrate solvates of loracarbef |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3502663A (en) * | 1969-04-21 | 1970-03-24 | Lilly Co Eli | Crystalline cephalosporin,method for its manufacture |
| US3531481A (en) * | 1969-04-21 | 1970-09-29 | Lilly Co Eli | Method for manufacture of crystalline cephalosporin |
| US4775751A (en) * | 1985-06-03 | 1988-10-04 | Eli Lilly & Company | Process for cephalexin hydrochloride alcoholates |
| YU46699B (sh) * | 1987-10-06 | 1994-04-05 | Eli Lilly And Co. | Kristalni monohidratni oblik 1-karbacefalosporina |
| US4977257A (en) * | 1988-11-14 | 1990-12-11 | Eli Lilly And Company | DMF solvates of a β-lactam antibiotic |
| CA2002597C (en) * | 1988-11-14 | 1999-03-23 | Thomas M. Eckrich | Solvates of b-lactam antibiotic |
| CA2002596A1 (en) * | 1988-11-14 | 1990-05-14 | Thomas M. Eckrich | Hydrates of b-lactam antibiotic |
| US5374719A (en) * | 1993-06-04 | 1994-12-20 | Eli Lilly And Company | Process for converting loracarbef dihydrate to loracarbef monohydrate |
| US5352782A (en) * | 1993-06-04 | 1994-10-04 | Eli Lilly And Company | Process for preparing crystalline β-lactam monohydrate |
| US5399686A (en) * | 1993-06-04 | 1995-03-21 | Eli Lilly And Company | Loracarbef isopropanolate and a process for converting loracarbef isopropanolate to loracarbef monohydrate |
-
1995
- 1995-03-01 US US08/396,948 patent/US5580977A/en not_active Expired - Lifetime
-
1996
- 1996-02-20 ZA ZA9601341A patent/ZA961341B/xx unknown
- 1996-02-21 AR ARP960101460A patent/AR002709A1/es not_active Application Discontinuation
- 1996-02-22 IL IL11722896A patent/IL117228A/xx active IP Right Grant
- 1996-02-24 TW TW085102100A patent/TW330205B/zh active
- 1996-02-26 PE PE1996000129A patent/PE28097A1/es not_active Application Discontinuation
- 1996-02-26 CO CO96008863A patent/CO4700429A1/es unknown
- 1996-02-27 ES ES96301303T patent/ES2135165T3/es not_active Expired - Lifetime
- 1996-02-27 DK DK96301303T patent/DK0729959T3/da active
- 1996-02-27 DE DE69603995T patent/DE69603995T2/de not_active Expired - Fee Related
- 1996-02-27 SI SI9630108T patent/SI0729959T1/xx not_active IP Right Cessation
- 1996-02-27 AT AT96301303T patent/ATE184006T1/de not_active IP Right Cessation
- 1996-02-27 EP EP96301303A patent/EP0729959B1/en not_active Expired - Lifetime
- 1996-02-28 CA CA002213812A patent/CA2213812A1/en not_active Abandoned
- 1996-02-28 RU RU97116165/04A patent/RU2160261C2/ru active
- 1996-02-28 WO PCT/US1996/002586 patent/WO1996026942A1/en not_active Ceased
- 1996-02-28 CN CN96193438A patent/CN1061349C/zh not_active Expired - Fee Related
- 1996-02-28 AU AU51742/96A patent/AU694639B2/en not_active Ceased
- 1996-02-28 BR BR9607308A patent/BR9607308A/pt not_active Application Discontinuation
- 1996-02-28 JP JP8526365A patent/JPH11501032A/ja not_active Ceased
- 1996-02-28 CZ CZ972728A patent/CZ272897A3/cs unknown
- 1996-02-28 NZ NZ304534A patent/NZ304534A/en unknown
- 1996-02-28 KR KR1019970706072A patent/KR19980702666A/ko not_active Abandoned
- 1996-02-28 TR TR97/00877T patent/TR199700877T1/xx unknown
- 1996-02-28 HU HU9702151A patent/HUP9702151A3/hu unknown
- 1996-02-28 PL PL96322111A patent/PL322111A1/xx unknown
-
1997
- 1997-08-20 NO NO973835A patent/NO308471B1/no not_active IP Right Cessation
-
1999
- 1999-11-25 GR GR990403040T patent/GR3031947T3/el unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM1K | Lapsed by not paying the annual fees |
Free format text: LAPSED IN AUGUST 2002 |