IL117228A - Process for preparing loracarbef monohydrate - Google Patents
Process for preparing loracarbef monohydrateInfo
- Publication number
- IL117228A IL117228A IL11722896A IL11722896A IL117228A IL 117228 A IL117228 A IL 117228A IL 11722896 A IL11722896 A IL 11722896A IL 11722896 A IL11722896 A IL 11722896A IL 117228 A IL117228 A IL 117228A
- Authority
- IL
- Israel
- Prior art keywords
- preparing
- loracarbef monohydrate
- loracarbef
- monohydrate
- preparing loracarbef
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
- C07D463/16—Nitrogen atoms
- C07D463/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
- C07D463/20—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D463/22—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/396,948 US5580977A (en) | 1995-03-01 | 1995-03-01 | Process for preparing loracarbef monohydrate |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL117228A0 IL117228A0 (en) | 1996-06-18 |
| IL117228A true IL117228A (en) | 2000-12-06 |
Family
ID=23569249
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL11722896A IL117228A (en) | 1995-03-01 | 1996-02-22 | Process for preparing loracarbef monohydrate |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US5580977A (xx) |
| EP (1) | EP0729959B1 (xx) |
| JP (1) | JPH11501032A (xx) |
| KR (1) | KR19980702666A (xx) |
| CN (1) | CN1061349C (xx) |
| AR (1) | AR002709A1 (xx) |
| AT (1) | ATE184006T1 (xx) |
| AU (1) | AU694639B2 (xx) |
| BR (1) | BR9607308A (xx) |
| CA (1) | CA2213812A1 (xx) |
| CO (1) | CO4700429A1 (xx) |
| CZ (1) | CZ272897A3 (xx) |
| DE (1) | DE69603995T2 (xx) |
| DK (1) | DK0729959T3 (xx) |
| ES (1) | ES2135165T3 (xx) |
| GR (1) | GR3031947T3 (xx) |
| HU (1) | HUP9702151A3 (xx) |
| IL (1) | IL117228A (xx) |
| NO (1) | NO308471B1 (xx) |
| NZ (1) | NZ304534A (xx) |
| PE (1) | PE28097A1 (xx) |
| PL (1) | PL322111A1 (xx) |
| RU (1) | RU2160261C2 (xx) |
| SI (1) | SI0729959T1 (xx) |
| TR (1) | TR199700877T1 (xx) |
| TW (1) | TW330205B (xx) |
| WO (1) | WO1996026942A1 (xx) |
| ZA (1) | ZA961341B (xx) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100540046B1 (ko) | 1997-11-12 | 2006-01-10 | 미쓰비시 가가꾸 가부시키가이샤 | 퓨린유도체 및 이를 유효성분으로 함유하는 의약 |
| ES2206227T3 (es) | 1999-05-11 | 2004-05-16 | Mitsubishi Chemical Corporation | Dihidrato de un derivado de purina, farmacos que lo contienen como ingrediente activo, e intermedio en su preparacion. |
| US6410520B2 (en) | 2000-02-01 | 2002-06-25 | The Procter & Gamble Company | Selective crystallization of 3-pyridyl-1-hydroxyethylidene-1, 1-bisphosphonic acid sodium as the hemipentahydrate or monohydrate |
| US6562974B2 (en) | 2000-02-01 | 2003-05-13 | The Procter & Gamble Company | Process for making geminal bisphosphonates |
| AU2003283624A1 (en) * | 2002-11-21 | 2004-06-15 | Ranbaxy Laboratories Limited | Monohydrate solvates of loracarbef |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3531481A (en) * | 1969-04-21 | 1970-09-29 | Lilly Co Eli | Method for manufacture of crystalline cephalosporin |
| US3502663A (en) * | 1969-04-21 | 1970-03-24 | Lilly Co Eli | Crystalline cephalosporin,method for its manufacture |
| US4775751A (en) * | 1985-06-03 | 1988-10-04 | Eli Lilly & Company | Process for cephalexin hydrochloride alcoholates |
| EG18529A (en) * | 1987-10-06 | 1993-04-30 | Lilly Co Eli | Process for preparing b-lactam hydrate |
| CA2002596A1 (en) * | 1988-11-14 | 1990-05-14 | Thomas M. Eckrich | Hydrates of b-lactam antibiotic |
| US4977257A (en) * | 1988-11-14 | 1990-12-11 | Eli Lilly And Company | DMF solvates of a β-lactam antibiotic |
| US5399686A (en) * | 1993-06-04 | 1995-03-21 | Eli Lilly And Company | Loracarbef isopropanolate and a process for converting loracarbef isopropanolate to loracarbef monohydrate |
| US5374719A (en) * | 1993-06-04 | 1994-12-20 | Eli Lilly And Company | Process for converting loracarbef dihydrate to loracarbef monohydrate |
| US5352782A (en) * | 1993-06-04 | 1994-10-04 | Eli Lilly And Company | Process for preparing crystalline β-lactam monohydrate |
-
1995
- 1995-03-01 US US08/396,948 patent/US5580977A/en not_active Expired - Lifetime
-
1996
- 1996-02-20 ZA ZA9601341A patent/ZA961341B/xx unknown
- 1996-02-21 AR ARP960101460A patent/AR002709A1/es not_active Application Discontinuation
- 1996-02-22 IL IL11722896A patent/IL117228A/xx active IP Right Grant
- 1996-02-24 TW TW085102100A patent/TW330205B/zh active
- 1996-02-26 CO CO96008863A patent/CO4700429A1/es unknown
- 1996-02-26 PE PE1996000129A patent/PE28097A1/es not_active Application Discontinuation
- 1996-02-27 DK DK96301303T patent/DK0729959T3/da active
- 1996-02-27 AT AT96301303T patent/ATE184006T1/de not_active IP Right Cessation
- 1996-02-27 SI SI9630108T patent/SI0729959T1/xx not_active IP Right Cessation
- 1996-02-27 EP EP96301303A patent/EP0729959B1/en not_active Expired - Lifetime
- 1996-02-27 ES ES96301303T patent/ES2135165T3/es not_active Expired - Lifetime
- 1996-02-27 DE DE69603995T patent/DE69603995T2/de not_active Expired - Fee Related
- 1996-02-28 JP JP8526365A patent/JPH11501032A/ja not_active Ceased
- 1996-02-28 KR KR1019970706072A patent/KR19980702666A/ko active IP Right Grant
- 1996-02-28 NZ NZ304534A patent/NZ304534A/en unknown
- 1996-02-28 CZ CZ972728A patent/CZ272897A3/cs unknown
- 1996-02-28 TR TR97/00877T patent/TR199700877T1/xx unknown
- 1996-02-28 CA CA002213812A patent/CA2213812A1/en not_active Abandoned
- 1996-02-28 RU RU97116165/04A patent/RU2160261C2/ru active
- 1996-02-28 BR BR9607308A patent/BR9607308A/pt not_active Application Discontinuation
- 1996-02-28 HU HU9702151A patent/HUP9702151A3/hu unknown
- 1996-02-28 WO PCT/US1996/002586 patent/WO1996026942A1/en not_active Application Discontinuation
- 1996-02-28 PL PL96322111A patent/PL322111A1/xx unknown
- 1996-02-28 CN CN96193438A patent/CN1061349C/zh not_active Expired - Fee Related
- 1996-02-28 AU AU51742/96A patent/AU694639B2/en not_active Ceased
-
1997
- 1997-08-20 NO NO973835A patent/NO308471B1/no not_active IP Right Cessation
-
1999
- 1999-11-25 GR GR990403040T patent/GR3031947T3/el unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted |