DK0768310T3 - Fremgangsmåde til fremstilling af imidazo-benzodiazepin-derivater - Google Patents

Fremgangsmåde til fremstilling af imidazo-benzodiazepin-derivater

Info

Publication number
DK0768310T3
DK0768310T3 DK96115949T DK96115949T DK0768310T3 DK 0768310 T3 DK0768310 T3 DK 0768310T3 DK 96115949 T DK96115949 T DK 96115949T DK 96115949 T DK96115949 T DK 96115949T DK 0768310 T3 DK0768310 T3 DK 0768310T3
Authority
DK
Denmark
Prior art keywords
imidazo
preparation
benzodiazepine derivatives
benzodiazepine
derivatives
Prior art date
Application number
DK96115949T
Other languages
Danish (da)
English (en)
Inventor
Karl-Heinz Bender
Manfred Breuninger
Manfred Froom
Siegfried Schmitt
Kurt Steiner
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of DK0768310T3 publication Critical patent/DK0768310T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02Muscle relaxants, e.g. for tetanus or cramps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK96115949T 1995-10-10 1996-10-04 Fremgangsmåde til fremstilling af imidazo-benzodiazepin-derivater DK0768310T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH285495 1995-10-10

Publications (1)

Publication Number Publication Date
DK0768310T3 true DK0768310T3 (da) 2000-04-17

Family

ID=4243076

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96115949T DK0768310T3 (da) 1995-10-10 1996-10-04 Fremgangsmåde til fremstilling af imidazo-benzodiazepin-derivater

Country Status (14)

Country Link
US (1) US5693795A (tr)
EP (1) EP0768310B1 (tr)
JP (1) JP3007050B2 (tr)
CN (1) CN1060776C (tr)
AR (1) AR003800A1 (tr)
AT (1) ATE187727T1 (tr)
BR (1) BR9605030A (tr)
CA (1) CA2184802C (tr)
DE (1) DE59603916D1 (tr)
DK (1) DK0768310T3 (tr)
ES (1) ES2141428T3 (tr)
GR (1) GR3032600T3 (tr)
MX (1) MX9604687A (tr)
TR (1) TR199600779A2 (tr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6512114B1 (en) * 1999-06-30 2003-01-28 Abbott Laboratories Process for the preparation of Midazolam
US6262260B1 (en) * 2000-03-23 2001-07-17 Abbott Laboratories Process for the preparation of midazolam
JP4298212B2 (ja) * 2002-03-29 2009-07-15 大日本印刷株式会社 塩酸エピナスチン高融点型結晶の製造法
EP2249791A4 (en) * 2008-02-08 2014-01-08 Colgate Palmolive Co COMPOSITIONS AND DEVICES
EP2249790A4 (en) * 2008-02-08 2014-02-19 Colgate Palmolive Co BASIC AMINO ACID AND A SOLUBLE CARBONATE SALT CONTAINING COMPOSITIONS
AU2009212321B2 (en) * 2008-02-08 2012-04-19 Colgate-Palmolive Company Compositions and methods for the treatment of xerostomia
CN101938990A (zh) * 2008-02-08 2011-01-05 高露洁-棕榄公司 包含碱性氨基酸肽和蛋白酶的组合物和方法
BRPI0907108A2 (pt) * 2008-02-08 2016-07-26 Colgate Palmolive Co escova de dentes.
MY155410A (en) * 2008-02-08 2015-10-15 Colgate Palmolive Co Compositions and devices
US20110044914A1 (en) * 2008-02-08 2011-02-24 Colgate -Palmolive Company Cleaning compositions and methods
MX2010005190A (es) 2008-02-08 2010-06-03 Colgate Palmolive Co Hilo dental.
AU2009212328B2 (en) * 2008-02-08 2011-12-08 Colgate-Palmolive Company Effervescent compositions
AU2009212339B2 (en) * 2008-02-08 2011-12-22 Colgate-Palmolive Company Tooth sealant
IT1399764B1 (it) * 2010-05-04 2013-05-03 F S I Fabbrica Italiana Sint Procedimento per la sintesi di 4h-imidazo [1,5-a][1,4]benzodiazepine, in particolare di midazolam.
UA110640C2 (uk) 2011-05-05 2016-01-25 Янссен Фармацевтика Нв ПРОТИГРИБКОВІ 5,6-ДИГІДРО-4Н-ПІРОЛО[1,2-a][1,4]БЕНЗОДІАЗЕПІНИ ТА 6Н-ПІРОЛО[1,2-a][1,4]БЕНЗОДІАЗЕПІНИ, ЯКІ ЗАМІЩЕНІ ГЕТЕРОЦИКЛІЧНИМИ ПОХІДНИМИ
WO2018035246A1 (en) 2016-08-16 2018-02-22 Uwm Research Foundation, Inc. Gaba(a) receptor modulators and methods to control airway hyperresponsiveness and inflammation in asthma
CN113603635B (zh) * 2021-10-08 2021-12-24 湖南速博生物技术有限公司 一种芳香族二元羧酸酯水解脱羧的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4307237A (en) * 1974-09-11 1981-12-22 Hoffmann-La Roche Inc. Imidazoles
US4280957A (en) * 1974-09-11 1981-07-28 Hoffmann-La Roche Inc. Imidazodiazepines and processes therefor
DE2609486A1 (de) * 1975-08-07 1977-05-12 Hoffmann La Roche Imidazo eckige klammer auf 1,5-a eckige klammer zu eckige klammer auf 1,4 eckige klammer zu diazepin-verbindungen und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
MX9604687A (es) 1997-04-30
CA2184802A1 (en) 1997-04-11
TR199600779A2 (tr) 1997-04-22
JP3007050B2 (ja) 2000-02-07
US5693795A (en) 1997-12-02
EP0768310A1 (de) 1997-04-16
CN1060776C (zh) 2001-01-17
BR9605030A (pt) 1998-06-30
ATE187727T1 (de) 2000-01-15
AR003800A1 (es) 1998-09-09
DE59603916D1 (de) 2000-01-20
GR3032600T3 (en) 2000-05-31
CN1150152A (zh) 1997-05-21
ES2141428T3 (es) 2000-03-16
CA2184802C (en) 2007-07-31
JPH09110871A (ja) 1997-04-28
EP0768310B1 (de) 1999-12-15

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