AR046081A1 - Inhibidores heterociclicos de mek y uso de los mismos - Google Patents

Inhibidores heterociclicos de mek y uso de los mismos

Info

Publication number
AR046081A1
AR046081A1 ARP040103151A ARP040103151A AR046081A1 AR 046081 A1 AR046081 A1 AR 046081A1 AR P040103151 A ARP040103151 A AR P040103151A AR P040103151 A ARP040103151 A AR P040103151A AR 046081 A1 AR046081 A1 AR 046081A1
Authority
AR
Argentina
Prior art keywords
heteroaryl
aryl
heterocyclyl
arylalkyl
alkyl
Prior art date
Application number
ARP040103151A
Other languages
English (en)
Spanish (es)
Inventor
Eli M Wallace
T Brian Hurley
Joseph Lyssikatos
Hong Wong Yang
Jim Blake
Allison L Marlow
Original Assignee
Array Biopharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Array Biopharma Inc filed Critical Array Biopharma Inc
Publication of AR046081A1 publication Critical patent/AR046081A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
ARP040103151A 2003-09-03 2004-09-02 Inhibidores heterociclicos de mek y uso de los mismos AR046081A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10/654,580 US7144907B2 (en) 2003-09-03 2003-09-03 Heterocyclic inhibitors of MEK and methods of use thereof

Publications (1)

Publication Number Publication Date
AR046081A1 true AR046081A1 (es) 2005-11-23

Family

ID=34218110

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP040103151A AR046081A1 (es) 2003-09-03 2004-09-02 Inhibidores heterociclicos de mek y uso de los mismos

Country Status (18)

Country Link
US (5) US7144907B2 (enExample)
EP (1) EP1673339B1 (enExample)
JP (1) JP4131741B2 (enExample)
KR (1) KR20060070558A (enExample)
CN (1) CN1874769A (enExample)
AR (1) AR046081A1 (enExample)
AU (1) AU2004270699B2 (enExample)
BR (1) BRPI0414111A (enExample)
CA (1) CA2537321A1 (enExample)
IL (4) IL173936A (enExample)
IS (1) IS8392A (enExample)
MX (1) MXPA06002466A (enExample)
NO (1) NO20061506L (enExample)
PT (1) PT1673339E (enExample)
RU (1) RU2006109599A (enExample)
TW (1) TW200526607A (enExample)
WO (1) WO2005023759A2 (enExample)
ZA (1) ZA200602581B (enExample)

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EP1673339A4 (en) 2009-04-29
US20060189668A1 (en) 2006-08-24
WO2005023759A3 (en) 2005-09-22
CN1874769A (zh) 2006-12-06
BRPI0414111A (pt) 2006-10-31
TW200526607A (en) 2005-08-16
IL219669A0 (en) 2012-06-28
IL219670A (en) 2013-03-24
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US7230099B2 (en) 2007-06-12
US7511058B2 (en) 2009-03-31
EP1673339B1 (en) 2013-07-03
IL219670A0 (en) 2012-06-28
WO2005023759A2 (en) 2005-03-17
JP4131741B2 (ja) 2008-08-13
US20050054701A1 (en) 2005-03-10
US20050049419A1 (en) 2005-03-03
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US20060189649A1 (en) 2006-08-24
KR20060070558A (ko) 2006-06-23
IL173936A (en) 2012-07-31
CA2537321A1 (en) 2005-03-17
ZA200602581B (en) 2007-06-27
EP1673339A2 (en) 2006-06-28
JP2007504241A (ja) 2007-03-01
US7271178B2 (en) 2007-09-18
AU2004270699A1 (en) 2005-03-17
US7144907B2 (en) 2006-12-05
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RU2006109599A (ru) 2007-10-10
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