KR20060070558A - Ｍｅｋ의 헤테로시클릭 억제제 및 이의 사용 방법 - Google Patents

Ｍｅｋ의 헤테로시클릭 억제제 및 이의 사용 방법 Download PDF

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Publication number
KR20060070558A
KR20060070558A KR1020067004505A KR20067004505A KR20060070558A KR 20060070558 A KR20060070558 A KR 20060070558A KR 1020067004505 A KR1020067004505 A KR 1020067004505A KR 20067004505 A KR20067004505 A KR 20067004505A KR 20060070558 A KR20060070558 A KR 20060070558A
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KR
South Korea
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aryl
heteroaryl
heterocyclyl
alkyl
arylalkyl
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KR1020067004505A
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English (en)
Korean (ko)
Inventor
엘리 월러스
브라이언 헐리
훈 운 양
요셉 리시카토스
앨리슨 엘. 말로우
짐 블레이크
Original Assignee
어레이 바이오파마 인크.
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Withdrawn legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
KR1020067004505A 2003-09-03 2004-09-01 Ｍｅｋ의 헤테로시클릭 억제제 및 이의 사용 방법 Withdrawn KR20060070558A (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US10/654,580 US7144907B2 (en) 2003-09-03 2003-09-03 Heterocyclic inhibitors of MEK and methods of use thereof
US10/654,580 2003-09-03
US10/929,295 2004-08-30
US10/929,295 US7230099B2 (en) 2003-09-03 2004-08-30 Heterocyclic inhibitors of MEK and methods of use thereof

Publications (1)

Publication Number Publication Date
KR20060070558A true KR20060070558A (ko) 2006-06-23

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ID=34218110

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020067004505A Withdrawn KR20060070558A (ko) 2003-09-03 2004-09-01 Ｍｅｋ의 헤테로시클릭 억제제 및 이의 사용 방법

Country Status (18)

Country Link
US (5) US7144907B2 (enExample)
EP (1) EP1673339B1 (enExample)
JP (1) JP4131741B2 (enExample)
KR (1) KR20060070558A (enExample)
CN (1) CN1874769A (enExample)
AR (1) AR046081A1 (enExample)
AU (1) AU2004270699B2 (enExample)
BR (1) BRPI0414111A (enExample)
CA (1) CA2537321A1 (enExample)
IL (4) IL173936A (enExample)
IS (1) IS8392A (enExample)
MX (1) MXPA06002466A (enExample)
NO (1) NO20061506L (enExample)
PT (1) PT1673339E (enExample)
RU (1) RU2006109599A (enExample)
TW (1) TW200526607A (enExample)
WO (1) WO2005023759A2 (enExample)
ZA (1) ZA200602581B (enExample)

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IL219670A0 (en) 2012-06-28
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IL173936A (en) 2012-07-31
AR046081A1 (es) 2005-11-23
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US7511058B2 (en) 2009-03-31
EP1673339A2 (en) 2006-06-28
US20060189649A1 (en) 2006-08-24
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EP1673339A4 (en) 2009-04-29
AU2004270699B2 (en) 2011-11-10
IL219671A0 (en) 2012-06-28
US20050049419A1 (en) 2005-03-03
BRPI0414111A (pt) 2006-10-31
WO2005023759A3 (en) 2005-09-22
JP4131741B2 (ja) 2008-08-13
IL219669A0 (en) 2012-06-28
US7271178B2 (en) 2007-09-18
IL219670A (en) 2013-03-24
US7144907B2 (en) 2006-12-05
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IS8392A (is) 2006-03-31
IL173936A0 (en) 2006-07-05
TW200526607A (en) 2005-08-16
CN1874769A (zh) 2006-12-06
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US20060189808A1 (en) 2006-08-24
US20060189668A1 (en) 2006-08-24
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US7230099B2 (en) 2007-06-12
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US20050054701A1 (en) 2005-03-10
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