AR045819A1 - Derivados de benzimidazol composiciones que los contienen, preparacion de los mismos y usos de los mismos - Google Patents

Derivados de benzimidazol composiciones que los contienen, preparacion de los mismos y usos de los mismos

Info

Publication number
AR045819A1
AR045819A1 ARP040103467A ARP040103467A AR045819A1 AR 045819 A1 AR045819 A1 AR 045819A1 AR P040103467 A ARP040103467 A AR P040103467A AR P040103467 A ARP040103467 A AR P040103467A AR 045819 A1 AR045819 A1 AR 045819A1
Authority
AR
Argentina
Prior art keywords
alkyl
cycloalkyl
aryl
heterocyclyl
cycloalkenyl
Prior art date
Application number
ARP040103467A
Other languages
English (en)
Spanish (es)
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of AR045819A1 publication Critical patent/AR045819A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/18—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/08—Radicals containing only hydrogen and carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/14—Radicals substituted by nitrogen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ARP040103467A 2003-09-26 2004-09-24 Derivados de benzimidazol composiciones que los contienen, preparacion de los mismos y usos de los mismos AR045819A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0302573A SE0302573D0 (sv) 2003-09-26 2003-09-26 Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof

Publications (1)

Publication Number Publication Date
AR045819A1 true AR045819A1 (es) 2005-11-16

Family

ID=29246982

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP040103467A AR045819A1 (es) 2003-09-26 2004-09-24 Derivados de benzimidazol composiciones que los contienen, preparacion de los mismos y usos de los mismos

Country Status (33)

Country Link
US (1) US8633235B2 (https=)
EP (1) EP1670769B1 (https=)
JP (1) JP4896721B2 (https=)
KR (1) KR101170184B1 (https=)
CN (2) CN102010373A (https=)
AR (1) AR045819A1 (https=)
AT (1) ATE430135T1 (https=)
AU (1) AU2004276062B2 (https=)
BR (1) BRPI0414780B8 (https=)
CA (1) CA2539738C (https=)
CO (1) CO5680443A2 (https=)
CY (1) CY1110332T1 (https=)
DE (1) DE602004020907D1 (https=)
DK (1) DK1670769T3 (https=)
ES (1) ES2324669T3 (https=)
HR (1) HRP20090388T1 (https=)
IL (1) IL174215A0 (https=)
IS (1) IS8422A (https=)
MX (1) MXPA06003197A (https=)
MY (1) MY140630A (https=)
NO (1) NO20061839L (https=)
NZ (1) NZ545736A (https=)
PL (1) PL1670769T3 (https=)
PT (1) PT1670769E (https=)
RU (1) RU2346938C2 (https=)
SA (1) SA04250310B1 (https=)
SE (1) SE0302573D0 (https=)
SI (1) SI1670769T1 (https=)
TW (1) TW200521117A (https=)
UA (1) UA86776C2 (https=)
UY (1) UY28536A1 (https=)
WO (1) WO2005030732A1 (https=)
ZA (3) ZA200602446B (https=)

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EP1558252B1 (en) 2002-08-02 2007-10-10 Merck & Co., Inc. Substituted furo [2,3-b]pyridine derivatives
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WO2006033631A1 (en) * 2004-09-24 2006-03-30 Astrazeneca Ab Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof i
UA87327C2 (ru) * 2004-09-24 2009-07-10 Астразенека Аб Производные бензимидазола, композиция, которая их содержит, их получение и применение
MX2007003105A (es) 2004-09-24 2007-06-07 Aztrazeneca Ab Derivados de bencimidazol, composiciones que los contienen, sus preparaciones y sus usos i.
WO2006033630A1 (en) * 2004-09-24 2006-03-30 Astrazeneca Ab Compounds, compositions containing them, preparation thereof and uses thereof iii
MX2007005290A (es) 2004-11-02 2007-07-09 Pfizer Derivados de sulfonilbencimidazol.
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TW200745049A (en) 2006-03-23 2007-12-16 Astrazeneca Ab New crystalline forms
TW200808769A (en) 2006-04-18 2008-02-16 Astrazeneca Ab Therapeutic compounds
US20080139846A1 (en) * 2006-09-01 2008-06-12 Astrazeneca Ab New Process 298
EP2070927A4 (en) * 2006-09-13 2010-10-13 Kyowa Hakko Kirin Co Ltd CONDENSED HETEROCYCLIC DERIVATIVE
US20110086853A1 (en) * 2009-10-08 2011-04-14 William Brown Therapeutic Compounds
RU2414899C1 (ru) * 2009-12-29 2011-03-27 Аверин Константин Михайлович Средства для лечения рассеянного склероза
RU2454234C1 (ru) * 2011-03-16 2012-06-27 Константин Михайлович Аверин Соли 1,3-диэтилбензимидазолия - иммуностимулирующие средства и фармацевтические композиции на их основе
UA119740C2 (uk) * 2012-06-13 2019-08-12 Сайтек Текнолоджи Корп. Композиції стабілізатора, що містять заміщені хроманові сполуки, і способи застосування
SI2864291T1 (sl) 2012-06-26 2017-01-31 Bayer Pharma Aktiengesellschaft N-(4-(kinolin-4-iloksi)cikloheksil(metil))(hetero)arilkarboksamidi kot antagonisti receptorja androgena, njihova izdelava in uporaba kot medicinski izdelki
JP2021515767A (ja) 2018-03-07 2021-06-24 バイエル・アクチエンゲゼルシヤフト Ｅｒｋ５阻害剤の同定及び使用
WO2020234103A1 (en) 2019-05-21 2020-11-26 Bayer Aktiengesellschaft Identification and use of kras inhibitors
CN112010789A (zh) * 2019-05-31 2020-12-01 中国科学院上海药物研究所 乙烯基磺酰胺或乙烯基酰胺类化合物及其制备方法和用途
GB202019335D0 (en) * 2020-12-08 2021-01-20 Artelo Biosciences Ltd Pharmaceutical compositions
WO2023166450A1 (ko) * 2022-03-04 2023-09-07 삼진제약주식회사 신규한 헤테로 고리 화합물 및 이를 포함하는 약학적 조성물

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WO2006033631A1 (en) 2004-09-24 2006-03-30 Astrazeneca Ab Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof i
EP1797070A1 (en) 2004-09-24 2007-06-20 AstraZeneca AB Compounds, compositions containing them, preparations thereof and uses thereof ii
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Also Published As

Publication number Publication date
UY28536A1 (es) 2005-04-29
ZA200702131B (en) 2008-08-27
SE0302573D0 (sv) 2003-09-26
ZA200702226B (en) 2009-01-28
KR101170184B1 (ko) 2012-07-31
CA2539738A1 (en) 2005-04-07
DK1670769T3 (da) 2009-08-10
SI1670769T1 (sl) 2009-10-31
PT1670769E (pt) 2009-07-09
MY140630A (en) 2010-01-15
SA04250310B1 (ar) 2009-01-19
HRP20090388T1 (hr) 2009-08-31
ATE430135T1 (de) 2009-05-15
CN102010373A (zh) 2011-04-13
AU2004276062A1 (en) 2005-04-07
JP4896721B2 (ja) 2012-03-14
CO5680443A2 (es) 2006-09-29
CN1886379A (zh) 2006-12-27
ES2324669T3 (es) 2009-08-12
MXPA06003197A (es) 2006-06-23
US20080207612A1 (en) 2008-08-28
TW200521117A (en) 2005-07-01
BRPI0414780B1 (pt) 2018-10-23
BRPI0414780B8 (pt) 2021-05-25
RU2006113371A (ru) 2007-11-10
ZA200602446B (en) 2007-09-26
PL1670769T3 (pl) 2009-09-30
BRPI0414780A (pt) 2006-11-21
AU2004276062B2 (en) 2008-05-22
KR20070001052A (ko) 2007-01-03
US8633235B2 (en) 2014-01-21
NO20061839L (no) 2006-06-26
IL174215A0 (en) 2006-08-01
EP1670769B1 (en) 2009-04-29
CA2539738C (en) 2011-11-22
UA86776C2 (ru) 2009-05-25
DE602004020907D1 (de) 2009-06-10
WO2005030732A1 (en) 2005-04-07
HK1089436A1 (en) 2006-12-01
RU2346938C2 (ru) 2009-02-20
NZ545736A (en) 2009-11-27
EP1670769A1 (en) 2006-06-21
JP2007506721A (ja) 2007-03-22
CY1110332T1 (el) 2015-01-14
IS8422A (is) 2006-04-21

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