AR045290A1 - Acido graso desaturasas de primula - Google Patents

Acido graso desaturasas de primula

Info

Publication number
AR045290A1
AR045290A1 ARP040102992A ARP040102992A AR045290A1 AR 045290 A1 AR045290 A1 AR 045290A1 AR P040102992 A ARP040102992 A AR P040102992A AR P040102992 A ARP040102992 A AR P040102992A AR 045290 A1 AR045290 A1 AR 045290A1
Authority
AR
Argentina
Prior art keywords
seq
polynucleotide
desaturase
polypeptide
sequence
Prior art date
Application number
ARP040102992A
Other languages
English (en)
Inventor
Virginia Ursin
Byron Froman
Jennifer Gonzales
Steven Screen
Fenggao Dong
Rosa Thomas La
Original Assignee
Monsanto Technology Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34272508&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR045290(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Monsanto Technology Llc filed Critical Monsanto Technology Llc
Publication of AR045290A1 publication Critical patent/AR045290A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/8247Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409Fatty acids
    • C12P7/6427Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Nutrition Science (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Métodos y composiciones que se refieren a enzimas desaturasa que modulan la cantidad y ubicación de enlaces dobles en ácidos grasos poli-insaturados de cadena larga (LC-PUFA). En particular, se relaciona con métodos y composiciones para mejorar los perfiles de ácidos grasos omega-3 en productos vegetales y partes de plantas usando enzimas desaturasa y ácidos nucleicos que codifican dichas enzimas. En realizaciones particulares, las enzimas desaturasa son desaturasa de Primula. También se proveen composiciones mejoradas de aceite de soja que contienen SDA y un contenido beneficioso general de ácidos grasos omega-3 con relación a ácidos grasos omega-6. Reivindicación 1: Un polinucleótido aislado que codifica un polipéptido con actividad desaturasa que desatura una molécula de ácido graso en el carbono 6, donde dicho polinucleótido se selecciona del grupo formado por: a) un polinucleótido que codifica la secuencia de polipéptidos de las SEQ ID N°: 4, SEQ ID N°: 5, SEQ ID N°: 22, SEQ ID N°: 24, SEQ ID N°: 26, SEQ ID N°: 46 o SEQ ID N°: 48; b) un polinucleótido que comprende la secuencia de ácido nucleico de las SEQ ID N°: 2, SEQ ID N°: 3, SEQ ID N°: 21, SEQ ID N°: 23, SEQ ID N°: 25, SEQ ID N°: 45 o SEQ ID N°: 47; c) un polinucleótido que se hibridiza con las SEQ ID N°:2, SEQ ID N°: 3, SEQ ID N°: 21, SEQ ID N°: 23, SEQ ID N°: 25, SEQ ID N°: 45 o SEQ ID N°: 47, o un complemento de las mismas, bajo condiciones de SSC 5X, formamida 50 % y 42° C; y d) un polinucleótido que codifica un polipéptido con al menos un 90 % de identidad de secuencia con la secuencia de polipéptidos de las SEQ ID N°: 4, SEQ ID N°: 5, SEQ ID N°: 22, SEQ ID N°: 24, SEQ ID N°: 26, SEQ ID N°: 46 o SEQ ID N°: 48. Reivindicación 6: Un vector recombinante que comprende la secuencia de polinucleótidos aislada de la cláusula 1. Reivindicación 12: Una planta transgénica transformada con el vector recombinante de la cláusula 6.
ARP040102992A 2003-08-21 2004-08-20 Acido graso desaturasas de primula AR045290A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US49675103P 2003-08-21 2003-08-21

Publications (1)

Publication Number Publication Date
AR045290A1 true AR045290A1 (es) 2005-10-19

Family

ID=34272508

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP040102992A AR045290A1 (es) 2003-08-21 2004-08-20 Acido graso desaturasas de primula

Country Status (16)

Country Link
US (5) US8173870B2 (es)
EP (1) EP1656449B1 (es)
CN (1) CN1871353B (es)
AR (1) AR045290A1 (es)
AT (1) ATE430802T1 (es)
AU (1) AU2004268196B2 (es)
BR (1) BRPI0413786B1 (es)
CA (2) CA2535310C (es)
DE (1) DE602004021001D1 (es)
DK (1) DK1656449T3 (es)
ES (1) ES2323644T3 (es)
MX (1) MXPA06002028A (es)
PL (1) PL1656449T3 (es)
PT (1) PT1656449E (es)
WO (1) WO2005021761A1 (es)
ZA (1) ZA200601438B (es)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2542420T3 (es) * 2002-05-22 2015-08-05 Monsanto Technology Llc Desaturasas de ácidos grasos de hongos
MXPA06002028A (es) 2003-08-21 2006-05-17 Monsanto Technology Llc Desaturasas de acido graso de primula.
CA2562548C (en) * 2004-04-16 2019-08-20 Monsanto Technology Llc Expression of fatty acid desaturases in corn
CN102559364B (zh) 2004-04-22 2016-08-17 联邦科学技术研究组织 用重组细胞合成长链多不饱和脂肪酸
CA2563875C (en) 2004-04-22 2015-06-30 Commonwealth Scientific And Industrial Research Organisation Synthesis of long-chain polyunsaturated fatty acids by recombinant cells
BRPI0517095B1 (pt) 2004-11-04 2018-05-29 Monsanto Technology Llc Processo para preparação de uma composição de óleo
DE102005052551A1 (de) * 2005-11-02 2007-05-16 Rothamsted Res Harpenden Verfahren zur Herstellung von y-Linolensäure und/oder Stearidonsäure in transgenen Brassicaceae und Linaceae
EP1965658B2 (en) * 2005-11-18 2022-10-05 Commonwealth Scientific and Industrial Research Organisation Feedstuffs for aquaculture comprising stearidonic acid feedstuffs for aquaculture
BRPI0708535A2 (pt) * 2006-03-03 2011-05-31 Monsanto Technology Llc meios para melhora da saúde cardiovascular
BRPI0714390B1 (pt) 2006-07-19 2018-05-15 Monsanto Technology Llc Polinucleotídeo, construção de dna, célula hospedeira fúngica ou bacteriana, processo para produção de alimento ou de produto alimentício e composição para alimento ou produto alimentício
RU2009111266A (ru) 2006-08-29 2010-10-10 Коммонвелт Сайентифик энд Индастриал Рисерч Организейшн (AU) Синтез жирных кислот
BRPI0806266A2 (pt) 2007-01-03 2011-09-06 Monsanto Technology Llc composições alimentìcias que incorporam ácidos graxos de cadeia longa adicionais
JP2010516230A (ja) * 2007-01-03 2010-05-20 モンサント テクノロジー エルエルシー ステアリドン酸を取り込む食物組成物
US8847006B2 (en) 2007-03-28 2014-09-30 Monsanto Technology Llc Utility of SNP markers associated with major soybean plant maturity and growth habit genomic regions
WO2009032559A1 (en) * 2007-08-31 2009-03-12 Monsanto Technology Llc Novel 7s-alpha regulatory elements for expressing transgenes in plants
US8343753B2 (en) * 2007-11-01 2013-01-01 Wake Forest University School Of Medicine Compositions, methods, and kits for polyunsaturated fatty acids from microalgae
WO2009073397A1 (en) * 2007-11-29 2009-06-11 Monsanto Technology Llc Meat products with increased levels of beneficial fatty acids
BRPI0908809A2 (pt) * 2008-02-15 2015-08-18 Monsanto Technology Llc Planta de soja e semente correspondente ao evento transgênico mon87769 e métodos para sua detecção
EP2337791B1 (en) * 2008-10-14 2013-07-24 Monsanto Technology LLC Utilization of fatty acid desaturases from hemiselmis spp
EP2358882B1 (en) 2008-11-18 2017-07-26 Commonwealth Scientific and Industrial Research Organisation Enzymes and methods for producing omega-3 fatty acids
CN106417970A (zh) 2009-03-16 2017-02-22 孟山都技术公司 包含有益脂肪酸的家禽肉和蛋
US8323708B2 (en) 2009-03-16 2012-12-04 Monsanto Technology Llc Poultry meat and eggs comprising beneficial fatty acids
US20100266746A1 (en) * 2009-04-16 2010-10-21 Monsanto Technology Llc Spread formulations including stearidonic acid
CN107087780A (zh) 2009-06-30 2017-08-25 孟山都技术公司 富含ω‑3的坚果黄油及其相关产物
US20120308682A1 (en) * 2009-11-30 2012-12-06 Monsanto Technology Llc Ruminant feed, products, and methods comprising beneficial fatty acids
US8372465B2 (en) * 2010-02-17 2013-02-12 Bunge Oils, Inc. Oil compositions of stearidonic acid
CN101914148A (zh) * 2010-08-20 2010-12-15 中国科学院遗传与发育生物学研究所 与脂肪酸合成相关的蛋白GmLEC1A及其编码基因与应用
US20150005382A1 (en) * 2011-10-04 2015-01-01 Wake Forest University Health Sciences (WFUHS) Methods for Identifying and Treating an Individual with an Inflammatory Disease using Fatty Acid-Based Therapies
EP2861059B1 (en) 2012-06-15 2017-05-03 Commonwealth Scientific and Industrial Research Organisation Production of long chain polyunsaturated fatty acids in plant cells
NZ721036A (en) 2013-12-18 2023-07-28 Grains Res & Dev Corp Lipid comprising long chain polyunsaturated fatty acids
CN105219789B (zh) 2014-06-27 2023-04-07 联邦科学技术研究组织 包含二十二碳五烯酸的提取的植物脂质
WO2020055763A1 (en) * 2018-09-11 2020-03-19 Nuseed Pty Ltd Methods of identifying dha canola ns-b50027-4

Family Cites Families (184)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB715352A (en) 1952-02-06 1954-09-15 Melville Edward Dunkley Process for the treatment of oil-bearing vegetable material
US3488198A (en) * 1967-03-01 1970-01-06 Beatrice Foods Co Filled milk product
US3676157A (en) * 1970-07-16 1972-07-11 Kelco Co Method of preparing freeze-thaw stable spoonable salad dressing
US4089880A (en) 1975-03-13 1978-05-16 Sullivan Systems Inc. Proces for refining fatty oils
DE2922146A1 (de) 1979-01-19 1980-07-24 Intercell Ag Verfahren und anlage zur verlustfreien lagerung von koernerfruechten und samen, sowie anwendung des verfahrens
US4273790A (en) * 1979-11-19 1981-06-16 Standard Brands Incorporated Low-fat liquid spread and process
MX7580E (es) 1981-10-15 1989-11-23 Cpc International Inc Procedimiento para la refinacion de aceites vegetales crudos
US4757011A (en) * 1983-09-30 1988-07-12 E. I. Du Pont De Nemours And Company Herbicide resistant tobacco
US4792523A (en) * 1984-08-31 1988-12-20 Cetus Corporation 3'Expression enhancing fragments and method
CH663951A5 (fr) * 1984-10-10 1988-01-29 Nestle Sa Procede d'enrichissement selectif en acides gras polyinsatures d'un melange contenant des acides gras fractions enrichies obtenues et compositions les contenant.
US4940835A (en) * 1985-10-29 1990-07-10 Monsanto Company Glyphosate-resistant plants
US4789554A (en) 1985-12-05 1988-12-06 The Procter & Gamble Company High temperature vacuum steam distillation process to purify and increase the frylife of edible oils
US4944954A (en) 1986-04-23 1990-07-31 Epe Incorporated Vegetable oil extraction process
JPS6344843A (ja) 1986-08-13 1988-02-25 Kao Corp 油中水中油型乳化油脂組成物
US4913921A (en) * 1987-09-11 1990-04-03 General Mills, Inc. Food products containing fish oils stabilized with fructose
DE3856382T2 (de) 1987-12-31 2000-05-11 Pioneer Hi Bred Int Raps mit erhöhtem Ölsäuregehalt
US5638637A (en) 1987-12-31 1997-06-17 Pioneer Hi-Bred International, Inc. Production of improved rapeseed exhibiting an enhanced oleic acid content
US4915972A (en) 1988-01-05 1990-04-10 Prosoya Corporation Food processing in oxygen-free environment
US4948811A (en) 1988-01-26 1990-08-14 The Procter & Gamble Company Salad/cooking oil balanced for health benefits
US5534425A (en) 1988-02-03 1996-07-09 Iowa State University Research Foundation, Inc. Soybeans having low linolenic acid content and method of production
GB8813766D0 (en) 1988-06-10 1988-07-13 Efamol Holdings Essential fatty acid compositions
US5990387A (en) * 1988-06-10 1999-11-23 Pioneer Hi-Bred International, Inc. Stable transformation of plant cells
US5286886A (en) 1988-06-21 1994-02-15 Van Den Bergh Foods Co., Division Of Conopco, Inc. Method of refining glyceride oils
GB8814732D0 (en) 1988-06-21 1988-07-27 Unilever Plc Method of refining clyceride oils
US5985348A (en) * 1995-06-07 1999-11-16 Omegatech, Inc. Milk products having high concentrations of omega-3 highly unsaturated fatty acids
US5340594A (en) * 1988-09-07 1994-08-23 Omegatech Inc. Food product having high concentrations of omega-3 highly unsaturated fatty acids
US5057419A (en) * 1988-09-22 1991-10-15 Rutgers University Genetically engineered plasmid and organisms for the production of specialized oils
CA2024811A1 (en) * 1989-02-24 1990-08-25 David A. Fischhoff Synthetic plant genes and method for preparation
CH678181A5 (es) * 1989-05-22 1991-08-15 Nestle Sa
US6803499B1 (en) * 1989-08-09 2004-10-12 Dekalb Genetics Corporation Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof
US7705215B1 (en) * 1990-04-17 2010-04-27 Dekalb Genetics Corporation Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof
US5550318A (en) 1990-04-17 1996-08-27 Dekalb Genetics Corporation Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof
US5097093A (en) * 1989-08-30 1992-03-17 Pioneer Hi-Bred International, Inc. Inbred corn line PHJ33
US5557037A (en) 1989-12-05 1996-09-17 Iowa State University Research Foundation, Inc. Soybeans having elevated contents of saturated fatty acids
US5585535A (en) 1990-01-05 1996-12-17 Iowa State University Research Foundation, Inc. Soybeans and soybean products having low palmitic acid content
US5484956A (en) * 1990-01-22 1996-01-16 Dekalb Genetics Corporation Fertile transgenic Zea mays plant comprising heterologous DNA encoding Bacillus thuringiensis endotoxin
CA2074355C (en) 1990-01-22 2008-10-28 Ronald C. Lundquist Method of producing fertile transgenic corn plants
GB2241503A (en) 1990-02-15 1991-09-04 Unilever Plc Edible fatty composition containing bleached fish oils
US7037692B1 (en) * 1990-03-16 2006-05-02 Calgene, Inc. Plant desaturases compositions and uses
WO1991013972A1 (en) 1990-03-16 1991-09-19 Calgene, Inc. Plant desaturases - compositions and uses
US6117677A (en) * 1990-03-16 2000-09-12 Thompson; Gregory A. Plant stearoyl-ACP desaturases genes
ATE152572T1 (de) 1990-04-04 1997-05-15 Pioneer Hi Bred Int Herstellung von rapssamen mit verringertem gehalt an gesättigten fettsäuren
EP0457950B1 (fr) * 1990-05-23 1993-10-20 Societe Des Produits Nestle S.A. Utilisation de l'acide stéaridonique pour le traitement des maladies inflammatoires
CA2083259C (en) 1990-05-25 2007-05-15 William D. Hitz Nucleotide sequence of soybean stearoyl-acp desaturase gene
US5349123A (en) * 1990-12-21 1994-09-20 Calgene, Inc. Glycogen biosynthetic enzymes in plants
US5498830A (en) * 1990-06-18 1996-03-12 Monsanto Company Decreased oil content in plant seeds
US6395966B1 (en) 1990-08-09 2002-05-28 Dekalb Genetics Corp. Fertile transgenic maize plants containing a gene encoding the pat protein
US5861187A (en) * 1990-08-30 1999-01-19 Cargill, Incorporated Oil from canola seed with altered fatty acid profiles and a method of producing oil
US6022577A (en) 1990-12-07 2000-02-08 Nabisco Technology Company High stearic acid soybean oil blends
US5208058A (en) 1991-01-09 1993-05-04 Amano Jitsugyo Co., Ltd. Method for treating nuts
US5658767A (en) 1991-01-24 1997-08-19 Martek Corporation Arachidonic acid and methods for the production and use thereof
US5260077A (en) 1991-02-12 1993-11-09 The Lubrizol Corporation Vegetable oil compositions
US5405765A (en) * 1991-08-23 1995-04-11 University Of Florida Method for the production of transgenic wheat plants
US6270828B1 (en) 1993-11-12 2001-08-07 Cargrill Incorporated Canola variety producing a seed with reduced glucosinolates and linolenic acid yielding an oil with low sulfur, improved sensory characteristics and increased oxidative stability
US5750827A (en) 1991-09-30 1998-05-12 Cargill Incorporated Canola variety producing a seed with reduced glucosinolates and linolenic acid yielding an oil with low sulfur, improved sensory characteristics and increased oxidative stability
DK0779024T3 (da) 1991-09-30 2006-03-27 Cargill Inc Canola som frembringer frö med nedsat indhold af glucosinolater og linolensyre, som frembringer en olie med lavt svovlindhold
JPH0591886A (ja) * 1991-09-30 1993-04-16 Suntory Ltd 8,11−エイコサジエン酸及びこれを含有する脂質の製造方法
US5614393A (en) 1991-10-10 1997-03-25 Rhone-Poulenc Agrochimie Production of γ-linolenic acid by a Δ6-desaturase
US6355861B1 (en) * 1991-10-10 2002-03-12 Rhone-Poulenc Agrochimie Production of gamma linolenic acid by a Δ6-desaturase
PH31293A (en) * 1991-10-10 1998-07-06 Rhone Poulenc Agrochimie Production of y-linolenic acid by a delta6-desaturage.
US5710365A (en) 1991-10-24 1998-01-20 E. I. Du Pont De Nemours And Company Soybean products with improved carbohydrate composition and soybean plants
DK0616644T3 (da) * 1991-12-04 2003-10-27 Du Pont Fedtsyredesaturase-gener fra planter
CA2084348A1 (en) 1991-12-31 1993-07-01 David F. Hildebrand Fatty acid alteration by a d9 desaturase in transgenic plant tissue
DE69333034T2 (de) 1992-03-13 2004-04-01 Agrigenetics, Inc., San Diego Modifikation pflanzlicher Öle durch Verwendung von Desaturase
CA2109811A1 (en) 1992-04-03 1993-10-14 Kevin C. Spencer Method of improving the aroma and flavor of stored beverages and edible oils
EP0604662B1 (en) * 1992-07-07 2008-06-18 Japan Tobacco Inc. Method of transforming monocotyledon
US5315020A (en) 1992-07-29 1994-05-24 Praxair Technology, Inc. Method of recovering waste heat from edible oil deodorizer and improving product stability
US6872872B1 (en) 1992-11-17 2005-03-29 E. I. Du Pont De Nemours And Company Genes for microsomal delta-12 fatty acid desaturases and related enzymes from plants
DK0668919T3 (da) 1992-11-17 2003-09-15 Du Pont Gener for mikorsomale delta-12-fedtsyredesaturaser og beslægtede enzymer fra planter
US6372965B1 (en) 1992-11-17 2002-04-16 E.I. Du Pont De Nemours And Company Genes for microsomal delta-12 fatty acid desaturases and hydroxylases from plants
ATE152761T1 (de) 1992-12-03 1997-05-15 Unilever Nv Verfahren zum raffinieren von essbaren ölen
EP0684998A1 (en) 1993-02-05 1995-12-06 Monsanto Company Altered linolenic and linoleic acid content in plants
EP0685993B1 (en) 1993-02-25 2000-04-26 Cargill, Incorporated LOW LEVEL GLUCOSINOLATE $i(BRASSICA)
WO1994021762A1 (en) 1993-03-17 1994-09-29 Unilever N.V. Removal of phospholipids from glyceride oil
AU695940B2 (en) 1993-04-27 1998-08-27 Cargill Incorporated Non-hydrogenated canola oil for food applications
JPH08511579A (ja) 1993-06-17 1996-12-03 カージル,インコーポレーテッド 食用の流動性カノラ油
EP0937408B1 (fr) 1993-08-20 2004-02-11 Societe Des Produits Nestle S.A. Produit laitier comprenant une composition lipidique nutritionnelle
US5639645A (en) 1993-09-22 1997-06-17 Mitsubishi Corporation Recombinant Δ9 desaturase and a gene encoding the same
AU692791B2 (en) 1993-10-12 1998-06-18 Agrigenetics, Inc. Brassica napus variety AG019
WO1995013390A2 (en) 1993-11-10 1995-05-18 Calgene, Inc. Plant acyl acp thioesterase sequences
KR100224120B1 (ko) 1993-12-28 1999-10-15 마나배게이사꾸 지방산의불포화화효소유전자,그유전자를함유한벡터
US5530183A (en) 1994-01-10 1996-06-25 Iowa State University Research Foundation, Inc. Soybean variety 9253
US5520708A (en) 1994-04-26 1996-05-28 Iowa State University Research Foundation, Inc. Soybean oil ester fuel blends
CA2150741A1 (en) * 1994-06-17 1995-12-18 Susan Trimbo Pediatric lipid emulsion
EP0778896B1 (en) 1994-08-31 2015-01-07 E.I. Du Pont De Nemours And Company Nucleotides sequences of canola and soybean palmitoyl-acp thioesterase genes and their use in the regulation of fatty acid content of the oils of soybean and canola plants
US5545553A (en) 1994-09-26 1996-08-13 The Rockefeller University Glycosyltransferases for biosynthesis of oligosaccharides, and genes encoding them
US6310194B1 (en) 1994-09-26 2001-10-30 Carnegie Institution Of Washington Plant fatty acid hydroxylases
US5668292A (en) * 1994-09-26 1997-09-16 Carnegie Institution Of Washington Use of plant fatty acyl hydroxylases to produce hydroxylated fatty acids and derivatives in plants
US5654402A (en) * 1994-10-26 1997-08-05 Michigan State University Methods and compositions relating to plant Δ6 palmitoyl-acyl carrier protein desaturase
US5625130A (en) 1995-03-07 1997-04-29 Pioneer Hi-Bred International, Inc. Oilseed Brassica bearing an endogenous oil wherein the levels of oleic, alpha-linolenic, and saturated fatty acids are simultaneously provided in an atypical highly beneficial distribution via genetic control
US5955329A (en) 1995-05-15 1999-09-21 Calgene, Inc. Engineering plant thioesterases for altered substrate specificity
WO1996036684A1 (en) 1995-05-16 1996-11-21 Unilever N.V. Method for refining an edible oil
WO1996041852A1 (en) 1995-06-12 1996-12-27 Unilever N.V. Mild refining of triglyceride oil
CA2557769A1 (en) 1995-12-14 1997-06-19 Cargill, Incorporated Plants having mutant sequences that confer altered fatty acid profiles
US5795614A (en) * 1996-03-01 1998-08-18 Kraft Foods, Inc. Method of making a reduced fat emulsified dressing
AUPN838696A0 (en) * 1996-03-01 1996-03-21 Florigene Limited Genetic sequences encoding flavonoid pathway enzymes and uses therefor
US6077828A (en) * 1996-04-25 2000-06-20 Abbott Laboratories Method for the prevention and treatment of cachexia and anorexia
ZA973565B (en) 1996-04-26 1998-10-26 Du Pont Soybean oil having high oxidative stability
US6340485B1 (en) 1996-06-03 2002-01-22 Croda International Plc Compositions and uses thereof
EP0928185B1 (en) 1996-06-03 2003-09-03 CRODA INTERNATIONAL plc Compositions and uses thereof
US5850026A (en) 1996-07-03 1998-12-15 Cargill, Incorporated Canola oil having increased oleic acid and decreased linolenic acid content
US5850030A (en) 1996-12-23 1998-12-15 Iowa State University Research Foundation, Inc. Reduced linolenic acid production in soybeans
JPH10191885A (ja) 1997-01-14 1998-07-28 Nisshin Oil Mills Ltd:The 大豆・菜種配合油
US6376754B1 (en) 1997-03-07 2002-04-23 Asgrow Seed Company Plants having resistance to multiple herbicides and its use
US5959175A (en) 1997-04-09 1999-09-28 Thomas; Terry L. Sunflower albumin 5' regulatory region for the modification of plant seed lipid composition
US5977436A (en) * 1997-04-09 1999-11-02 Rhone Poulenc Agrochimie Oleosin 5' regulatory region for the modification of plant seed lipid composition
US6051754A (en) * 1997-04-11 2000-04-18 Abbott Laboratories Methods and compositions for synthesis of long chain poly-unsaturated fatty acids in plants
EP0996732B1 (en) 1997-04-11 2005-06-15 Calgene LLC Methods and compositions for synthesis of long chain polyunsaturated fatty acids in plants
US5968809A (en) * 1997-04-11 1999-10-19 Abbot Laboratories Methods and compositions for synthesis of long chain poly-unsaturated fatty acids
US6075183A (en) * 1997-04-11 2000-06-13 Abbott Laboratories Methods and compositions for synthesis of long chain poly-unsaturated fatty acids in plants
US5972664A (en) * 1997-04-11 1999-10-26 Abbott Laboratories Methods and compositions for synthesis of long chain poly-unsaturated fatty acids
WO1998050569A2 (en) 1997-05-05 1998-11-12 Dow Agrosciences Llc Nucleotide sequences of maize oleoyl-acp thioesterase and palmitoyl-acp thioesterase genes and their use in the modification of fatty acid content of oil
MY124156A (en) 1997-08-29 2006-06-30 Lipogenics Inc Process for stabilization of oil from plant materials
DE69840378D1 (de) 1998-02-13 2009-02-05 Lipidia Holding S A Raffinieren von essbaren Ölen mit höchstem antioxidativem Wirkungsgrad
US6229033B1 (en) 1998-05-11 2001-05-08 E. I. Du Pont De Nemours And Company Fat products from high stearic soybean oil and a method for the production thereof
US6426448B1 (en) 1998-05-11 2002-07-30 E. I. Du Pont De Nemours And Company Gene combinations that alter the quality and functionality of soybean oil
FR2779443B1 (fr) 1998-06-08 2000-08-04 Claude Hanni Dispositif de culture de cellules organiques et d'etude de leur activite electrophysiologique et membrane utilisee dans un tel dispositif
EP1086236B1 (en) * 1998-06-12 2007-09-05 Calgene LLC Polyunsaturated fatty acids in plants
JP4079516B2 (ja) 1998-06-19 2008-04-23 サントリー株式会社 トリグリセリドの製造方法
US6365802B2 (en) 1998-08-14 2002-04-02 Calgene Llc Methods for increasing stearate content in soybean oil
US6123978A (en) * 1998-08-31 2000-09-26 Mcneil-Ppc, Inc. Stable salad dressings
US6303849B1 (en) 1998-11-12 2001-10-16 Saskatchewan Wheat Pool Brassica juncea lines bearing endogenous edible oils
US6172248B1 (en) 1998-11-20 2001-01-09 Ip Holdings, L.L.C. Methods for refining vegetable oils and byproducts thereof
EP1141346A2 (en) * 1999-01-14 2001-10-10 Monsanto Co. Soybean transformation method
CA2260397A1 (en) 1999-01-29 2000-07-29 Atlantis Marine Inc. Method of converting rendered triglyceride oil from marine sources into bland, stable food oil
US6610867B2 (en) 2000-08-10 2003-08-26 Renessen Llc Corn oil processing and products comprising corn oil and corn meal obtained from corn
US6313328B1 (en) 1999-02-11 2001-11-06 Cargill, Incorporated Extraction of corn oil from flaked corn grain
US6388110B1 (en) 1999-02-11 2002-05-14 Cargill, Incorporated High oil corn processing
US6388113B1 (en) 1999-06-04 2002-05-14 Consejo Superior De Investigaciones Cientificas ( Csic) High oleic/high stearic sunflower oils
US6603061B1 (en) * 1999-07-29 2003-08-05 Monsanto Company Agrobacterium-mediated plant transformation method
ATE455172T1 (de) 1999-08-16 2010-01-15 Du Pont Verfahren zur herstellung von calendulasäure, einer fettsäure mit delta-8,10,12 konjugierten doppelbindungen und dimorphekolinsäure, einer fettsäure mit einer 9-hydroxyl-gruppe und delta- 10,12 konjugierten doppelbindungen
ATE383433T1 (de) 1999-08-26 2008-01-15 Calgene Llc Pflanzen mit veränderten mehrfachungesättigten fettsäuren
US7067722B2 (en) 1999-08-26 2006-06-27 Monsanto Technology Llc Nucleic acid sequences and methods of use for the production of plants with modified polyunsaturated fatty acids
NO313076B1 (no) * 1999-12-28 2002-08-12 Pronova Biocare As Flytende n¶rings- og/eller nytelsesmiddel og fremgangsmåte for fremstilling derav
US6184442B1 (en) 2000-01-06 2001-02-06 Asgrow Seed Company Llc Soybean cultivar 9323265446452
US6506965B1 (en) * 2000-02-04 2003-01-14 Rustica Prograin Genetique Inbred maize seed and plant RPK7346
US6369302B1 (en) 2000-03-08 2002-04-09 Asgrow Seed Company, Llc Soybean cultivar 958361722350
AU2001264880A1 (en) 2000-05-24 2001-12-03 The Texas A And M University System Degumming of edible oils by ultrafiltration
AU2001281024A1 (en) 2000-08-02 2002-02-13 The Board Of Regents Of The University Of Nebraska Down-regulation of single genes and simultaneous down-regulation of multiple genes by nuclear localization of rna transcripts
CN100421565C (zh) 2000-08-08 2008-10-01 花王株式会社 油/脂组合物
US6667064B2 (en) 2000-08-30 2003-12-23 Pilot Therapeutics, Inc. Composition and method for treatment of hypertriglyceridemia
AU2002218447C9 (en) * 2000-09-28 2008-04-17 Bioriginal Food & Science Corporation Fad4, Fad5, Fad5-2, and Fad6, fatty acid desaturase family members and uses thereof
US7037547B2 (en) * 2000-11-30 2006-05-02 Kraft Foods Holdings, Inc. Method of deflavoring soy-derived materials for use in beverages
SE523094C2 (sv) 2001-01-11 2004-03-30 Karlshamns Ab Förfarande för framställning av en fettkomposition som innehåller sterolestrar, fria steroler och glycerider, fettkomposition framställd genom förfarandet samt fettkompositionens användning
US6635451B2 (en) 2001-01-25 2003-10-21 Abbott Laboratories Desaturase genes and uses thereof
US6511690B1 (en) 2001-02-01 2003-01-28 Carolina Soy Products, Inc. Soybean oil process
EP1243273A1 (en) 2001-03-22 2002-09-25 Societe Des Produits Nestle S.A. Composition comprising a prebiotic for decreasing infammatory process and abnormal activation of non-specific immune parameters
JP4995377B2 (ja) 2001-04-26 2012-08-08 花王株式会社 油脂組成物
AU2002318135B2 (en) 2001-05-14 2007-08-02 Dsm Ip Assets B.V. Production and use of a polar lipid-rich fraction containing stearidonic acid and gamma linolenic acid from plant seeds and microbes
EP2261312A1 (en) 2001-12-12 2010-12-15 Martek Biosciences Corporation Extraction and Winterization of Lipids from Oilseed and Microbial Sources
GB2385852A (en) * 2002-02-27 2003-09-03 Rothamsted Ex Station Delta 6-desaturases from Primulaceae
CN101072509A (zh) 2002-03-08 2007-11-14 孟山都技术有限公司 炎症的治疗和预防
EP1484959A4 (en) 2002-03-21 2005-08-31 Monsanto Technology Llc NUCLEIC ACID CONSTRUCTS AND METHODS FOR PRODUCING MODIFIED SEED OIL COMPOSITIONS
US7166771B2 (en) 2002-06-21 2007-01-23 Monsanto Technology Llc Coordinated decrease and increase of gene expression of more than one gene using transgenic constructs
US7566813B2 (en) 2002-03-21 2009-07-28 Monsanto Technology, L.L.C. Nucleic acid constructs and methods for producing altered seed oil compositions
US20040107460A1 (en) * 2002-03-21 2004-06-03 Fillatti Joanne J. Nucleic acid constructs and methods for producing altered seed oil compositions
ES2542420T3 (es) * 2002-05-22 2015-08-05 Monsanto Technology Llc Desaturasas de ácidos grasos de hongos
EA013051B1 (ru) 2002-06-19 2010-02-26 ДСМ Ай Пи ЭССЕТС Б.В. Масло из микробных клеток, композиция, содержащая масло, и способ получения масла
MXPA05000195A (es) 2002-06-21 2005-04-08 Monsanto Technology Llc Secuencias de acido nucleico relacionadas con tioesterasa y metodos de uso para la produccion de plantas con composicion modificada de acido graso.
WO2004001000A2 (en) 2002-06-21 2003-12-31 Monsanto Technology Llc Intron double stranded rna constructs and uses thereof
US6791016B1 (en) 2003-01-31 2004-09-14 Pioneer Hi-Bred International, Inc. Soybean variety 93M40
US20040172682A1 (en) 2003-02-12 2004-09-02 Kinney Anthony J. Production of very long chain polyunsaturated fatty acids in oilseed plants
MY134678A (en) * 2003-05-05 2007-12-31 Malaysian Palm Oil Board A process for obtaining an oil composition and the oil composition obtained therefrom
US20050181019A1 (en) * 2003-07-03 2005-08-18 Slim-Fast Foods Company, Division Of Conopco, Inc. Nutrition bar
US7973212B2 (en) 2003-08-01 2011-07-05 Pioneer Hi-Bred International, Inc. Soybean plants having superior agronomic performance and methods for their production
WO2005012316A2 (de) 2003-08-01 2005-02-10 Basf Plant Science Gmbh Verfahren zur herstellung mehrfach ungesättigter fettsäuren in transgenen
MXPA06002028A (es) * 2003-08-21 2006-05-17 Monsanto Technology Llc Desaturasas de acido graso de primula.
US7579492B2 (en) 2003-09-30 2009-08-25 Carolina Soy Products Llc Two-stage extraction of soybean oil
AU2004290051A1 (en) * 2003-11-12 2005-05-26 E.I. Dupont De Nemours And Company Delta-15 desaturases suitable for altering levels of polyunsaturated fatty acids in oilseed plants and oleaginous yeast
US6924381B2 (en) 2003-12-24 2005-08-02 Carolina Soy Products, Llc Modified physical refining of soybean oil
PT1732379E (pt) 2004-04-09 2014-01-03 Monsanto Technology Llc Composições e métodos para o controlo de infestações de plantas por insectos
CA2562548C (en) * 2004-04-16 2019-08-20 Monsanto Technology Llc Expression of fatty acid desaturases in corn
US7344747B2 (en) * 2004-04-29 2008-03-18 Gfa Brands, Inc. Oxidative stabilization of omega-3 fatty acids in low linoleic acid-containing peanut butter
BRPI0511236A (pt) 2004-06-04 2007-11-27 Fluxome Sciences As método para a produção de ácidos graxos poliinsaturados com quatro ou mais ligações duplas, saccharomyces cerevisiae geneticamente modificado que tem capacidade de produzir ácidos graxos poliinsaturados com quatro ou mais ligações duplas quando desenvolvido em um substrato que não de ácido graxo, composição, uso da composição e uso de um saccharomyces cervisiae geneticamente modificado
TWI363600B (en) * 2004-09-21 2012-05-11 Kao Corp Acidic oil-in-water emulsion composition
AU2005291975B2 (en) 2004-09-29 2011-09-08 Monsanto Technology Llc High yielding soybean plants with low linolenic acid
BRPI0517095B1 (pt) * 2004-11-04 2018-05-29 Monsanto Technology Llc Processo para preparação de uma composição de óleo
JP4191189B2 (ja) 2005-12-08 2008-12-03 康生 梅津 がん関連遺伝子活性化能を有するペプチド
AU2013202935B2 (en) 2006-03-10 2016-05-26 Monsanto Technology Llc Soybean seed and oil compositions and methods of making same
WO2007106728A2 (en) 2006-03-10 2007-09-20 Monsanto Technology Llc Soybean seed and oil compositions and methods of making same
BRPI0714390B1 (pt) * 2006-07-19 2018-05-15 Monsanto Technology Llc Polinucleotídeo, construção de dna, célula hospedeira fúngica ou bacteriana, processo para produção de alimento ou de produto alimentício e composição para alimento ou produto alimentício
US20090110800A1 (en) * 2007-10-24 2009-04-30 Wilkes Richard S Food compositions incorporating additional long chain fatty acids
EP2337791B1 (en) * 2008-10-14 2013-07-24 Monsanto Technology LLC Utilization of fatty acid desaturases from hemiselmis spp
US9480271B2 (en) 2009-09-15 2016-11-01 Monsanto Technology Llc Soybean seed and oil compositions and methods of making same

Also Published As

Publication number Publication date
EP1656449A1 (en) 2006-05-17
PT1656449E (pt) 2009-07-27
US8221819B2 (en) 2012-07-17
US10174297B2 (en) 2019-01-08
US20170283780A1 (en) 2017-10-05
CA2881252A1 (en) 2005-03-10
US20130041031A1 (en) 2013-02-14
DE602004021001D1 (de) 2009-06-18
US8173870B2 (en) 2012-05-08
CA2535310C (en) 2015-06-09
AU2004268196A1 (en) 2005-03-10
CA2535310A1 (en) 2005-03-10
BRPI0413786A (pt) 2006-11-07
US20130041032A1 (en) 2013-02-14
CA2881252C (en) 2017-02-28
CN1871353B (zh) 2013-04-24
US9701947B2 (en) 2017-07-11
US20090176879A1 (en) 2009-07-09
WO2005021761A1 (en) 2005-03-10
ZA200601438B (en) 2007-05-30
ATE430802T1 (de) 2009-05-15
CN1871353A (zh) 2006-11-29
ES2323644T3 (es) 2009-07-22
DK1656449T3 (da) 2009-06-02
US20080063691A1 (en) 2008-03-13
MXPA06002028A (es) 2006-05-17
EP1656449B1 (en) 2009-05-06
US11041148B2 (en) 2021-06-22
PL1656449T3 (pl) 2009-08-31
BRPI0413786B1 (pt) 2019-12-24
AU2004268196B2 (en) 2010-03-04

Similar Documents

Publication Publication Date Title
AR045290A1 (es) Acido graso desaturasas de primula
AR062001A1 (es) Desaturasas de acido graso de tetraselmis suecica
AR039851A1 (es) Acido graso desaturasas de hongos y genes los mismos
ES2568803T3 (es) Reducción del contenido de ácidos grasos saturados en semillas de plantas
AR035534A1 (es) Secuencia de nucleotidos aislada, polipeptido purificado, metodo para producir una desaturasa, vector, celula huesped, celula de mamiferos, celula vegetal, una planta y tejido vegetal, planta transgenica, acidos o aceites vegetales, metodo para producir un acido graso poliinsaturado y composicion
AR025399A1 (es) Secuencias de acido nucleico y metodos de uso para la produccion de plantas con acidos grasos poliinsaturados modificados.
AR092778A1 (es) Produccion de dha (acido docosahexaenoico) y otros acidos grasos poli insaturados de cadena larga en plantas
AR021789A1 (es) Genes de la elongasa y usos de los mismos.
BRPI0510132A (pt) sìntese de ácidos graxos poliinsaturados de cadeia longa por células recombinantes
RU2008149700A (ru) Дельта-5-десатураза и ее применение для получения полиненасыщенных жирных кислот
ATE110778T1 (de) Nukleotidsequenz des gens für stearoyl-acp- desaturase aus soja.
AR059811A1 (es) Semillas de soja, composiciones de soja, y metodos para producirlas
AR099694A2 (es) Polinucleótido; vector recombinante; planta transgénica y método para producir aceite de semillas
UA99099C2 (en) Mutants fad-2 and high-oleinic plants
AR033547A1 (es) Polinucleotido aislado, construccion de acido nucleico, celula huesped, planta transgenica de brassica, soja y maiz, semilla y progenie de la misma, metodo para modificar el contenido de acidos grasos saturados en la celula huesped, metodo para incrementar la expresion de beta-cetoacil-acp sintetasa
AR074364A1 (es) Enzimas y metodo para producir acidos grasos omega -3
ATE402944T1 (de) Desaturasegene, von diesen codierte enzyme und verwendungen dafür
AR081201A1 (es) Produccion de dha (acido docosahexanoico ) y otros lc-pufas( acidos grasos poliinsaturados de cadena larga ) en plantas
AR030051A1 (es) Acido nucleico aislado, secuencia aislada, constructo genico, secuencias de aminoacidos, vector y organismo aislado que lo comprende, anticuerpo, molecula de acido nucleico antisentido, procedimiento para preparar acidos grasos poliinsaturados que lo emplea, aceite, lipidos o acidos grasos o una fra
AR000582A1 (es) Acidos nucleicos que codifica una delta 6 desaturasa en borraja vectores de expresión que lo contienen celulas que incluyen dichos vectores y organismos y plantas regeneradas a partir de dichas celulas y métodos para inducir la producción de ácidos gamma linolenico y otros ácidos polin-saturados
BRPI0413073A (pt) processo para a produção de compostos, óleo, lipìdeo ou ácido graxo, ou uma fração dos mesmos, composição de óleo, lipìdeo ou ácido graxo, processo para a produção de óleos, lipìdeos ou composições de ácido graxo, uso de óleo, lipìdeo ou ácidos graxos ou de composições de óleo, lipìdeo ou ácido graxo ou de óleos, lipìdeos ou composições de ácido graxo, seqüência de ácido nucleico isolado, seqüência de aminoácidos, construção de gene, vetor, e, organismo não humano transgênico
NO20043592L (no) Nytt elongasegen og fremgangsmate for fremstilling av flerumettede fettsyrer
AR065241A1 (es) Promotores de gen vegetal inducibles por nematodos y metodos para su uso
DE60114176D1 (de) Verfahren zur herstellung von cla-isomeren
AR098539A1 (es) Producción de ácido grasos poliinsaturados de cadena larga omega 3 en los cultivos de oleaginosas por una sintasa pufa traustoquitridio

Legal Events

Date Code Title Description
FG Grant, registration