AR081201A1 - Produccion de dha (acido docosahexanoico ) y otros lc-pufas( acidos grasos poliinsaturados de cadena larga ) en plantas - Google Patents

Produccion de dha (acido docosahexanoico ) y otros lc-pufas( acidos grasos poliinsaturados de cadena larga ) en plantas

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Publication number
AR081201A1
AR081201A1 ARP110101691A ARP110101691A AR081201A1 AR 081201 A1 AR081201 A1 AR 081201A1 AR P110101691 A ARP110101691 A AR P110101691A AR P110101691 A ARP110101691 A AR P110101691A AR 081201 A1 AR081201 A1 AR 081201A1
Authority
AR
Argentina
Prior art keywords
pufas
pufa
plants
production
organisms
Prior art date
Application number
ARP110101691A
Other languages
English (en)
Original Assignee
Martek Biosciences Corp
Dow Agrosciences Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Martek Biosciences Corp, Dow Agrosciences Llc filed Critical Martek Biosciences Corp
Publication of AR081201A1 publication Critical patent/AR081201A1/es

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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/8247—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
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    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
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    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
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    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6432—Eicosapentaenoic acids [EPA]
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    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6434—Docosahexenoic acids [DHA]
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    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
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    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1288—Transferases for other substituted phosphate groups (2.7.8)

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Abstract

La solicitud provee organismos huéspedes recombinantes (por ej., plantas) genéticamente modificados con un sistema de sintasa de ácido graso poliinsaturado (PUFA, por sus siglas en inglés) y una o más proteínas accesorias (por ej., PPTasa y/o ACoAS) que permiten la producción de PUFAs en el organismo huésped. La presente solicitud se refiere además a métodos para preparar y utilizar dichos organismos (por ej., para obtener PUFAs) así como también productos obtenidos a partir de ese tipo de organismos (por ej., aceite y/o semilla). Reivindicación 1: Una planta Brassica, su descendiente, célula, semilla o parte de la misma genéticamente modificada(o), que comprende: (i) una secuencia de ácidos nucleicos que codifica un sistema de sintasa de ácido graso poliinsaturado (PUFA, por sus siglas en inglés) que produce por lo menos un PUFA; y (ii) una secuencia de ácidos nucleicos que codifica una fosfopanteteinil-transferasa (PPTasa) que transfiere un cofactor de fosfopanteteinilo a un dominio de ACP del sistema de sintasa de PUFA.
ARP110101691A 2010-05-17 2011-05-17 Produccion de dha (acido docosahexanoico ) y otros lc-pufas( acidos grasos poliinsaturados de cadena larga ) en plantas AR081201A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US34553710P 2010-05-17 2010-05-17

Publications (1)

Publication Number Publication Date
AR081201A1 true AR081201A1 (es) 2012-07-04

Family

ID=44992026

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP110101691A AR081201A1 (es) 2010-05-17 2011-05-17 Produccion de dha (acido docosahexanoico ) y otros lc-pufas( acidos grasos poliinsaturados de cadena larga ) en plantas

Country Status (25)

Country Link
US (5) US20130150599A1 (es)
EP (3) EP3517617A1 (es)
JP (1) JP6059138B2 (es)
KR (1) KR102184432B1 (es)
CN (2) CN105296511A (es)
AR (1) AR081201A1 (es)
AU (1) AU2011256209B2 (es)
BR (1) BR112012029255A2 (es)
CA (2) CA3161375A1 (es)
CL (1) CL2012003210A1 (es)
EA (1) EA201291223A1 (es)
ES (1) ES2656217T3 (es)
HK (1) HK1179652A1 (es)
HU (1) HUE036182T2 (es)
IL (1) IL223045A0 (es)
MX (1) MX345243B (es)
MY (1) MY165098A (es)
NO (1) NO2571994T3 (es)
NZ (1) NZ604479A (es)
PL (1) PL2571994T3 (es)
PT (1) PT2571994T (es)
SG (1) SG185572A1 (es)
TW (1) TW201144442A (es)
UA (1) UA116613C2 (es)
WO (1) WO2011146524A1 (es)

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KR102580142B1 (ko) 2014-11-14 2023-09-19 바스프 플랜트 사이언스 컴퍼니 게엠베하 Pufa를 포함하는 식물 지질의 변형
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RU2017138655A (ru) 2015-04-15 2019-05-15 ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи Растительный промотор для экспрессии трансгена
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