AR033449A1 - Nuevo gen de elongasa y proceso para la produccion de acidos grasos delta9 poliinsaturados - Google Patents
Nuevo gen de elongasa y proceso para la produccion de acidos grasos delta9 poliinsaturadosInfo
- Publication number
- AR033449A1 AR033449A1 ARP020101099A ARP020101099A AR033449A1 AR 033449 A1 AR033449 A1 AR 033449A1 AR P020101099 A ARP020101099 A AR P020101099A AR P020101099 A ARP020101099 A AR P020101099A AR 033449 A1 AR033449 A1 AR 033449A1
- Authority
- AR
- Argentina
- Prior art keywords
- fatty acids
- sequence
- gene
- production
- new
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 4
- 235000014113 dietary fatty acids Nutrition 0.000 title abstract 2
- 229930195729 fatty acid Natural products 0.000 title abstract 2
- 239000000194 fatty acid Substances 0.000 title abstract 2
- 150000004665 fatty acids Chemical class 0.000 title abstract 2
- 235000020777 polyunsaturated fatty acids Nutrition 0.000 abstract 4
- 239000003921 oil Substances 0.000 abstract 3
- DTOSIQBPPRVQHS-PDBXOOCHSA-N alpha-linolenic acid Chemical compound CC\C=C/C\C=C/C\C=C/CCCCCCCC(O)=O DTOSIQBPPRVQHS-PDBXOOCHSA-N 0.000 abstract 2
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 235000020661 alpha-linolenic acid Nutrition 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- VZCCETWTMQHEPK-UHFFFAOYSA-N gamma-Linolensaeure Natural products CCCCCC=CCC=CCC=CCCCCC(O)=O VZCCETWTMQHEPK-UHFFFAOYSA-N 0.000 abstract 1
- VZCCETWTMQHEPK-QNEBEIHSSA-N gamma-linolenic acid Chemical compound CCCCC\C=C/C\C=C/C\C=C/CCCCC(O)=O VZCCETWTMQHEPK-QNEBEIHSSA-N 0.000 abstract 1
- 235000020664 gamma-linolenic acid Nutrition 0.000 abstract 1
- 229960002733 gamolenic acid Drugs 0.000 abstract 1
- 230000002068 genetic effect Effects 0.000 abstract 1
- 229960004488 linolenic acid Drugs 0.000 abstract 1
- 150000007523 nucleic acids Chemical group 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- DCXXMTOCNZCJGO-UHFFFAOYSA-N tristearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCCCCCCCCCC)COC(=O)CCCCCCCCCCCCCCCCC DCXXMTOCNZCJGO-UHFFFAOYSA-N 0.000 abstract 1
- 235000021122 unsaturated fatty acids Nutrition 0.000 abstract 1
- 150000004670 unsaturated fatty acids Chemical class 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
- C12N15/8247—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
- C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Nutrition Science (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Enzymes And Modification Thereof (AREA)
- Peptides Or Proteins (AREA)
- Fodder In General (AREA)
- Edible Oils And Fats (AREA)
Abstract
Se hace referencia a un nuevo gen de elongasa que tiene la secuencia ID. De SEC.No. 1: o sus derivados, a una construccion genética que comprende esta secuencia o sus derivados y a su uso. La secuencia de ácido nucleico de la invencion codifica un polipéptido que elonga ácido alfa-linolénico (C18:3 d9, 12, 15) en al menos dos átomos de carbono, mientras que el ácido gama-linolénico (C18:3 d6, 9, 12) no se elonga. Se refiere adicionalmente a vectores u organismos que comprenden un gen de elongasa que tiene la secuencia ID. de SEC. No.1, o sus derivados. Se hace referencia también a un proceso para la produccion de ácidos grasos poiinsaturados (=PUFAs) con un organismo que comprende el gen de elongasa y cuyo organismo produce grandes cantidades de aceites y, especialmente aceites con alto contenido de ácidos grasos insaturados. Adicionalmente, se refiere a una composicion de aceite y/o de ácido graso con un mayor contenido de ácidos grasos poliinsaturados C20 o C22 con al menos dos enlaces dobles y/o una composicion de triacilglicerol con un mayor contenido de dichos ácidos grasos poliinsaturados.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0107510.0A GB0107510D0 (en) | 2001-03-26 | 2001-03-26 | New elongase gene and a process for the production of -9-polyunsaturated fatty acids |
Publications (1)
Publication Number | Publication Date |
---|---|
AR033449A1 true AR033449A1 (es) | 2003-12-17 |
Family
ID=9911561
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP020101099A AR033449A1 (es) | 2001-03-26 | 2002-03-26 | Nuevo gen de elongasa y proceso para la produccion de acidos grasos delta9 poliinsaturados |
Country Status (17)
Country | Link |
---|---|
US (1) | US7601889B2 (es) |
EP (1) | EP1373519B1 (es) |
JP (1) | JP2004531248A (es) |
CN (1) | CN1537166A (es) |
AR (1) | AR033449A1 (es) |
AT (1) | ATE492641T1 (es) |
AU (1) | AU2002310891B2 (es) |
BR (1) | BR0208202A (es) |
CA (1) | CA2442010C (es) |
DE (1) | DE60238669D1 (es) |
DK (1) | DK1373519T3 (es) |
EE (1) | EE200300471A (es) |
ES (1) | ES2383451T3 (es) |
GB (1) | GB0107510D0 (es) |
IL (1) | IL157562A0 (es) |
NO (1) | NO20034276L (es) |
WO (1) | WO2002077213A2 (es) |
Families Citing this family (59)
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DE50312241D1 (de) * | 2002-01-30 | 2010-01-28 | Basf Plant Science Gmbh | Verfahren zur herstellung mehrfach ungesättigter f |
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GB0229578D0 (en) * | 2002-12-19 | 2003-01-22 | Univ Bristol | Novel method for the production of polyunsaturated fatty acids |
US20040172682A1 (en) * | 2003-02-12 | 2004-09-02 | Kinney Anthony J. | Production of very long chain polyunsaturated fatty acids in oilseed plants |
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US11952581B2 (en) | 2003-08-01 | 2024-04-09 | Basf Plant Science Gmbh | Process for the production of polyunsaturated fatty acids in transgenic organisms |
BRPI0413073A (pt) | 2003-08-01 | 2006-10-03 | Basf Plant Science Gmbh | processo para a produção de compostos, óleo, lipìdeo ou ácido graxo, ou uma fração dos mesmos, composição de óleo, lipìdeo ou ácido graxo, processo para a produção de óleos, lipìdeos ou composições de ácido graxo, uso de óleo, lipìdeo ou ácidos graxos ou de composições de óleo, lipìdeo ou ácido graxo ou de óleos, lipìdeos ou composições de ácido graxo, seqüência de ácido nucleico isolado, seqüência de aminoácidos, construção de gene, vetor, e, organismo não humano transgênico |
JP4567047B2 (ja) | 2004-02-27 | 2010-10-20 | ビーエーエスエフ プラント サイエンス ゲーエムベーハー | トランスジェニック植物における多価不飽和脂肪酸の製造方法 |
ATE528403T1 (de) | 2004-02-27 | 2011-10-15 | Basf Plant Science Gmbh | Verfahren zur herstellung von ungesättigten omega-3-fettsäuren in transgenen organismen |
CA2563875C (en) | 2004-04-22 | 2015-06-30 | Commonwealth Scientific And Industrial Research Organisation | Synthesis of long-chain polyunsaturated fatty acids by recombinant cells |
US7807849B2 (en) | 2004-04-22 | 2010-10-05 | Commonwealth Scientific And Industrial Research Organisation | Synthesis of long-chain polyunsaturated fatty acids by recombinant cells |
BRPI0511236A (pt) | 2004-06-04 | 2007-11-27 | Fluxome Sciences As | método para a produção de ácidos graxos poliinsaturados com quatro ou mais ligações duplas, saccharomyces cerevisiae geneticamente modificado que tem capacidade de produzir ácidos graxos poliinsaturados com quatro ou mais ligações duplas quando desenvolvido em um substrato que não de ácido graxo, composição, uso da composição e uso de um saccharomyces cervisiae geneticamente modificado |
BRPI0512481A (pt) * | 2004-06-25 | 2008-03-11 | Du Pont | polinucleotìdeo isolado, polipeptìdeo, construção recombinante, célula, yarrowia sp.transformada, métodos para transformar uma célula, produzir uma planta transformada, produzir levedura, produzir ácidos graxos poliinsaturados e produzir pelo menos um ácido graxo poliinsaturados, sementes, óleos, plantas de sementes oleaginosa e alimentos ou rações |
US7588931B2 (en) * | 2004-11-04 | 2009-09-15 | E. I. Du Pont De Nemours And Company | High arachidonic acid producing strains of Yarrowia lipolytica |
DE102005013779A1 (de) | 2005-03-22 | 2006-09-28 | Basf Plant Science Gmbh | Verfahren zur Herstellung von mehrfach ungesättigten C20- und C22-Fettsäuren mit mindestens vier Doppelbindungen in transgenen Pflanzen |
DE102005038036A1 (de) | 2005-08-09 | 2007-02-15 | Basf Plant Science Gmbh | Verfahren zur Herstellung von Arachidonsäure und/oder Eicosapentaensäure in transgenen Nutzpflanzen |
US7645604B2 (en) * | 2005-11-23 | 2010-01-12 | E.I. Du Pont De Nemours And Company | Delta-9 elongases and their use in making polyunsaturated fatty acids |
GB0603160D0 (en) | 2006-02-16 | 2006-03-29 | Rothamsted Res Ltd | Nucleic acid |
AR059376A1 (es) | 2006-02-21 | 2008-03-26 | Basf Plant Science Gmbh | Procedimiento para la produccion de acidos grasos poliinsaturados |
US7943823B2 (en) | 2006-04-28 | 2011-05-17 | E.I. Du Pont De Nemours And Company | Delta-8 desaturase and its use in making polyunsaturated fatty acids |
US7678560B2 (en) | 2006-05-17 | 2010-03-16 | E.I. Du Pont De Nemours And Company | Δ 5 desaturase and its use in making polyunsaturated fatty acids |
US7695950B2 (en) | 2006-05-17 | 2010-04-13 | E. I. Du Pont De Nemours And Company | Δ5 desaturase and its use in making polyunsaturated fatty acids |
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EP2054509A2 (de) | 2006-10-06 | 2009-05-06 | BASF Plant Science GmbH | Verfahren zur herstellung mehrfach ungesättigter fettsäuren in transgenen organismen |
US7863502B2 (en) | 2006-10-23 | 2011-01-04 | E.I. Dupont De Nemours And Company | Delta-8 desaturases and their use in making polyunsaturated fatty acids |
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CA2675207A1 (en) | 2007-02-12 | 2008-07-21 | E. I. Du Pont De Nemours And Company | Production of arachidonic acid in oilseed plants |
JP5083941B2 (ja) * | 2007-03-07 | 2012-11-28 | 学校法人北里研究所 | 食用動物の肥育仕上がり判定方法 |
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IL133272A0 (en) * | 1997-06-04 | 2001-04-30 | Calgene Llc | Production of polyunsaturated fatty acid by expression of polyketide-like synthesis genes in plants |
ATE346944T1 (de) | 1997-09-30 | 2006-12-15 | Univ California | Herstellung von proteinen in pflanzensamen |
KR20010033517A (ko) | 1997-12-23 | 2001-04-25 | 더 유니버시티 오브 브리스톨 | 불포화화효소 |
KR20010072555A (ko) | 1998-03-11 | 2001-07-31 | 한스 루돌프 하우스, 헨리테 브룬너, 베아트리체 귄터 | 신규한 식물 색소체 프로모터 서열 |
WO1999064616A2 (en) | 1998-06-12 | 1999-12-16 | Abbott Laboratories | Polyunsaturated fatty acids in plants |
US6677145B2 (en) | 1998-09-02 | 2004-01-13 | Abbott Laboratories | Elongase genes and uses thereof |
US6403349B1 (en) * | 1998-09-02 | 2002-06-11 | Abbott Laboratories | Elongase gene and uses thereof |
JP4383671B2 (ja) | 1998-12-07 | 2009-12-16 | ワシントン ステート ユニバーシティ リサーチ ファウンデーション | 不飽和化酵素、およびそれらを多価不飽和脂肪酸の合成のために用いる方法 |
CA2365096A1 (en) | 1999-03-18 | 2000-09-21 | The University Of Bristol | Polyunsaturated fatty acid (pufa) elongase from caenorhabditis elegans |
ES2331228T3 (es) | 2000-02-09 | 2009-12-28 | Basf Se | Nuevo gen de elongasa y proceso para la preparacion de acidos grasos poliinsaturados. |
PE20070235A1 (es) | 2005-08-17 | 2007-04-04 | Glaxosmithkline Biolog Sa | Vacuna que contiene rotavirus atenuado |
-
2001
- 2001-03-26 GB GBGB0107510.0A patent/GB0107510D0/en not_active Ceased
-
2002
- 2002-03-26 WO PCT/EP2002/003418 patent/WO2002077213A2/en active Application Filing
- 2002-03-26 US US10/472,321 patent/US7601889B2/en not_active Expired - Fee Related
- 2002-03-26 BR BR0208202-0A patent/BR0208202A/pt not_active Application Discontinuation
- 2002-03-26 JP JP2002576656A patent/JP2004531248A/ja active Pending
- 2002-03-26 AR ARP020101099A patent/AR033449A1/es active IP Right Grant
- 2002-03-26 CN CNA028073452A patent/CN1537166A/zh active Pending
- 2002-03-26 AT AT02735183T patent/ATE492641T1/de not_active IP Right Cessation
- 2002-03-26 CA CA2442010A patent/CA2442010C/en not_active Expired - Fee Related
- 2002-03-26 ES ES02735183T patent/ES2383451T3/es not_active Expired - Lifetime
- 2002-03-26 AU AU2002310891A patent/AU2002310891B2/en not_active Ceased
- 2002-03-26 EE EEP200300471A patent/EE200300471A/xx unknown
- 2002-03-26 IL IL15756202A patent/IL157562A0/xx unknown
- 2002-03-26 EP EP02735183A patent/EP1373519B1/en not_active Expired - Lifetime
- 2002-03-26 DE DE60238669T patent/DE60238669D1/de not_active Expired - Lifetime
- 2002-03-26 DK DK02735183.2T patent/DK1373519T3/da active
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2003
- 2003-09-25 NO NO20034276A patent/NO20034276L/no unknown
Also Published As
Publication number | Publication date |
---|---|
US7601889B2 (en) | 2009-10-13 |
WO2002077213A2 (en) | 2002-10-03 |
IL157562A0 (en) | 2004-03-28 |
GB0107510D0 (en) | 2001-05-16 |
CN1537166A (zh) | 2004-10-13 |
BR0208202A (pt) | 2004-04-13 |
CA2442010C (en) | 2013-07-30 |
EE200300471A (et) | 2003-12-15 |
ES2383451T3 (es) | 2012-06-21 |
NO20034276D0 (no) | 2003-09-25 |
WO2002077213A3 (en) | 2003-03-13 |
JP2004531248A (ja) | 2004-10-14 |
US20050089981A1 (en) | 2005-04-28 |
DE60238669D1 (de) | 2011-02-03 |
EP1373519A2 (en) | 2004-01-02 |
AU2002310891B2 (en) | 2008-01-24 |
NO20034276L (no) | 2003-10-22 |
DK1373519T3 (da) | 2011-04-18 |
CA2442010A1 (en) | 2002-10-03 |
EP1373519B1 (en) | 2010-12-22 |
ATE492641T1 (de) | 2011-01-15 |
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