BR0208202A - ácido necleico isolado, sequência de aminoácidos, construção de gene, vetor, organismo, processo para a produção de pufas, óleo, lipìdeo ou ácido graxo ou fração destes, composição oleaginosa, lipìdica ou de ácidos graxos, uso da mesma, anticorpo, sequência de nucleotìdeos anti-sentido, e, kit - Google Patents

ácido necleico isolado, sequência de aminoácidos, construção de gene, vetor, organismo, processo para a produção de pufas, óleo, lipìdeo ou ácido graxo ou fração destes, composição oleaginosa, lipìdica ou de ácidos graxos, uso da mesma, anticorpo, sequência de nucleotìdeos anti-sentido, e, kit

Info

Publication number
BR0208202A
BR0208202A BR0208202-0A BR0208202A BR0208202A BR 0208202 A BR0208202 A BR 0208202A BR 0208202 A BR0208202 A BR 0208202A BR 0208202 A BR0208202 A BR 0208202A
Authority
BR
Brazil
Prior art keywords
sequence
lipid
fatty acid
organism
acid
Prior art date
Application number
BR0208202-0A
Other languages
English (en)
Inventor
Johnathan A Napier
Colin M Lazarus
Baoxiu Qi
Jens Lerchl
Original Assignee
Univ Bristol
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Bristol filed Critical Univ Bristol
Publication of BR0208202A publication Critical patent/BR0208202A/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/8247—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Nutrition Science (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Fodder In General (AREA)
  • Edible Oils And Fats (AREA)
  • Peptides Or Proteins (AREA)

Abstract

"áCIDO NUCLEICO ISOLADO, SEQuêNCIA DE AMINOáCIDOS, CONSTRUçãO DE GENE, VETOR, ORGANISMO, PROCESSO PARA A PRODUçãO DE PUFAS, óLEO, LIPìDEO OU áCIDO GRAXO OU FRAçãO DESTES, COMPOSIçãO OLEAGINOSA, LIPìDICA OU DE áCIDOS GRAXOS, USO DA MESMA, ANTICORPO, SEQuêNCIA DE NUCLEOTìDEOS ANTI-SENTIDO, E, KIT". A invenção diz respeito a um novo gene elongase tendo a seq³ência SEQ ID NO: 1 ou seus derivados, a uma construção de gene que compreende esta seq³ência ou seus derivados, e a seu uso. A seq³ência de ácido nucleico inventiva codifica um polipeptídeo que alonga o ácido <244>-linolênico (C~ 18:3 d9,12,15~) em pelo menos dois átomos de carbono, enquanto o ácido <sym>-linolênico (C~ 18:3 d6, 9, 12~) não é alongado. A invenção adicionalmente diz respeito a vetores ou organismos que compreendem um gene elongase tendo a seq³ência SEQ ID NO: 1 ou seus derivados. A invenção ainda diz respeito a um processo para a produção de ácidos graxos poliinsaturados (=PUFAs) com um organismo que compreende o gene elongase, organismo este que produz altas quantidades de óleos e, especialmente, óleos com um alto teor de ácidos graxos insaturados. Adicionalmente, a invenção diz respeito a uma composição oleosa e/ou de ácido graxo com um teor mais elevado de ácidos graxos C~ 20~ OU C~ 22~ poliinsaturados com pelo menos duas ligações duplas, e/ou a uma composição de triacilglicerol com um teor mais elevado dos referidos ácidos graxos poliinsaturados.
BR0208202-0A 2001-03-26 2002-03-26 ácido necleico isolado, sequência de aminoácidos, construção de gene, vetor, organismo, processo para a produção de pufas, óleo, lipìdeo ou ácido graxo ou fração destes, composição oleaginosa, lipìdica ou de ácidos graxos, uso da mesma, anticorpo, sequência de nucleotìdeos anti-sentido, e, kit BR0208202A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0107510.0A GB0107510D0 (en) 2001-03-26 2001-03-26 New elongase gene and a process for the production of -9-polyunsaturated fatty acids
PCT/EP2002/003418 WO2002077213A2 (en) 2001-03-26 2002-03-26 New elongase gene and production of δ9-polyunsaturated fatty acids

Publications (1)

Publication Number Publication Date
BR0208202A true BR0208202A (pt) 2004-04-13

Family

ID=9911561

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0208202-0A BR0208202A (pt) 2001-03-26 2002-03-26 ácido necleico isolado, sequência de aminoácidos, construção de gene, vetor, organismo, processo para a produção de pufas, óleo, lipìdeo ou ácido graxo ou fração destes, composição oleaginosa, lipìdica ou de ácidos graxos, uso da mesma, anticorpo, sequência de nucleotìdeos anti-sentido, e, kit

Country Status (17)

Country Link
US (1) US7601889B2 (pt)
EP (1) EP1373519B1 (pt)
JP (1) JP2004531248A (pt)
CN (1) CN1537166A (pt)
AR (1) AR033449A1 (pt)
AT (1) ATE492641T1 (pt)
AU (1) AU2002310891B2 (pt)
BR (1) BR0208202A (pt)
CA (1) CA2442010C (pt)
DE (1) DE60238669D1 (pt)
DK (1) DK1373519T3 (pt)
EE (1) EE200300471A (pt)
ES (1) ES2383451T3 (pt)
GB (1) GB0107510D0 (pt)
IL (1) IL157562A0 (pt)
NO (1) NO20034276L (pt)
WO (1) WO2002077213A2 (pt)

Families Citing this family (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003206714B2 (en) * 2002-01-30 2007-09-06 Basf Plant Science Gmbh Elongase gene and method for producing polyunsaturated fatty acids
GB0229578D0 (en) * 2002-12-19 2003-01-22 Univ Bristol Novel method for the production of polyunsaturated fatty acids
BR0317304A (pt) * 2002-12-19 2005-11-08 Univ Bristol Processo para a produção de compostos, sequência de ácido nucleico isolada, sequência de aminoácidos, construção gênica, vetor, e, organismo
US20040172682A1 (en) * 2003-02-12 2004-09-02 Kinney Anthony J. Production of very long chain polyunsaturated fatty acids in oilseed plants
WO2004080198A2 (en) * 2003-03-12 2004-09-23 Nestec S.A. Puffed pet food for diet control
MX353906B (es) 2003-08-01 2018-02-02 Basf Plant Science Gmbh Metodo para la produccion de acidos grasos poli-insaturados en organismos transgenicos.
US11952581B2 (en) 2003-08-01 2024-04-09 Basf Plant Science Gmbh Process for the production of polyunsaturated fatty acids in transgenic organisms
ATE528403T1 (de) 2004-02-27 2011-10-15 Basf Plant Science Gmbh Verfahren zur herstellung von ungesättigten omega-3-fettsäuren in transgenen organismen
EP3543324B1 (de) 2004-02-27 2022-11-30 BASF Plant Science GmbH Verfahren zur herstellung mehrfach ungesättigten fettsäuren in transgenen pflanzen
EP2357243B1 (en) 2004-04-22 2018-12-12 Commonwealth Scientific and Industrial Research Organisation Synthesis of long-chain polyunsaturated fatty acids by recombinant cells
DK1756280T3 (en) 2004-04-22 2015-02-02 Commw Scient Ind Res Org SYNTHESIS OF CHAIN, polyunsaturated fatty acids BY RECOMBINANT CELLS
DK1766023T3 (da) 2004-06-04 2010-12-13 Fluxome Sciences As Metabolisk manipulerede celler til fremstillingen af polyumættede fedtsyrer
US7256033B2 (en) 2004-06-25 2007-08-14 E. I. Du Pont De Nemours And Company Delta-8 desaturase and its use in making polyunsaturated fatty acids
US7550286B2 (en) 2004-11-04 2009-06-23 E. I. Du Pont De Nemours And Company Docosahexaenoic acid producing strains of Yarrowia lipolytica
DE102005013779A1 (de) 2005-03-22 2006-09-28 Basf Plant Science Gmbh Verfahren zur Herstellung von mehrfach ungesättigten C20- und C22-Fettsäuren mit mindestens vier Doppelbindungen in transgenen Pflanzen
DE102005038036A1 (de) 2005-08-09 2007-02-15 Basf Plant Science Gmbh Verfahren zur Herstellung von Arachidonsäure und/oder Eicosapentaensäure in transgenen Nutzpflanzen
DK1951866T3 (da) 2005-11-23 2014-10-27 Du Pont Delta-9-elongaser og anvendelse heraf til fremstilling af flerumættede fedtsyrer
GB0603160D0 (en) 2006-02-16 2006-03-29 Rothamsted Res Ltd Nucleic acid
AR059376A1 (es) 2006-02-21 2008-03-26 Basf Plant Science Gmbh Procedimiento para la produccion de acidos grasos poliinsaturados
US7943823B2 (en) 2006-04-28 2011-05-17 E.I. Du Pont De Nemours And Company Delta-8 desaturase and its use in making polyunsaturated fatty acids
US7678560B2 (en) 2006-05-17 2010-03-16 E.I. Du Pont De Nemours And Company Δ 5 desaturase and its use in making polyunsaturated fatty acids
US7695950B2 (en) 2006-05-17 2010-04-13 E. I. Du Pont De Nemours And Company Δ5 desaturase and its use in making polyunsaturated fatty acids
EP2059588A4 (en) 2006-08-29 2010-07-28 Commw Scient Ind Res Org FATTY ACID SYNTHESIS
CA2847007C (en) 2006-10-06 2016-11-08 Basf Plant Science Gmbh Process for the production of polyunsaturated fatty acids in transgenic organisms
EP2390338B1 (en) 2006-10-23 2013-08-21 E. I. du Pont de Nemours and Company Delta-8 desaturases and their use in making polyunsaturated fatty acids
US20080125487A1 (en) * 2006-11-17 2008-05-29 Tapas Das Elongase gene and uses thereof
US8916361B2 (en) 2006-11-17 2014-12-23 Abbott Laboratories Elongase gene and uses thereof
US8389808B2 (en) 2007-02-12 2013-03-05 E.I. Du Pont De Nemours And Company Production of arachidonic acid in oilseed plants
JP5083941B2 (ja) * 2007-03-07 2012-11-28 学校法人北里研究所 食用動物の肥育仕上がり判定方法
US8362317B2 (en) 2007-03-09 2013-01-29 Monsanto Technology Llc Preparation and use of plant embryo explants for transformation
MX2009010574A (es) 2007-04-03 2009-10-22 Du Pont Multienzimas y su uso en la fabricacion de acidos grasos poliinsaturados.
US7790156B2 (en) 2007-04-10 2010-09-07 E. I. Du Pont De Nemours And Company Δ-8 desaturases and their use in making polyunsaturated fatty acids
US8119860B2 (en) * 2007-04-16 2012-02-21 E. I. Du Pont De Nemours And Company Delta-9 elongases and their use in making polyunsaturated fatty acids
US8957280B2 (en) 2007-05-03 2015-02-17 E. I. Du Pont De Nemours And Company Delta-5 desaturases and their use in making polyunsaturated fatty acids
CN101820757A (zh) 2007-06-01 2010-09-01 普林斯顿大学托管委员会 通过调节宿主细胞代谢途径治疗病毒感染
CA2695112A1 (en) 2007-07-31 2009-02-05 Basf Plant Science Gmbh Elongases and processes for the production of polyunsaturated fatty acids in transgenic organisms
WO2009097331A1 (en) * 2008-01-28 2009-08-06 The Board Of Regents Of The University Of Oklahoma Very long chain polyunsaturated fatty acids, methods of production, and uses
US8168858B2 (en) 2008-06-20 2012-05-01 E. I. Du Pont De Nemours And Company Delta-9 fatty acid elongase genes and their use in making polyunsaturated fatty acids
BRPI0913897A2 (pt) * 2008-06-27 2016-11-01 Centre Nat Rech Scient células recombinantes e plantas de ácidos graxos de cadeias muito longas (agcml)
AU2009286755B2 (en) 2008-08-26 2015-10-22 Basf Plant Science Gmbh Nucleic acids encoding desaturases and modified plant oil
CN113957105B (zh) 2008-11-18 2024-11-01 联邦科学技术研究组织 产生ω-3脂肪酸的酶和方法
WO2010130725A1 (en) 2009-05-13 2010-11-18 Basf Plant Science Company Gmbh Acyltransferases and uses thereof in fatty acid production
CN102597242B (zh) 2009-06-08 2016-03-02 罗特哈姆斯泰德研究有限公司 新脂肪酸延伸组合物及其用途
AU2010272536B2 (en) 2009-07-17 2016-09-08 Basf Plant Science Company Gmbh Novel fatty acid desaturases and elongases and uses thereof
CA2772267A1 (en) 2009-08-31 2011-03-03 Basf Plant Science Company Gmbh Regulatory nucleic acid molecules for enhancing seed-specific gene expression in plants promoting enhanced polyunsaturated fatty acid synthesis
US9347049B2 (en) 2009-11-24 2016-05-24 Basf Plant Science Company Gmbh Fatty acid elongase and uses thereof
EP2504427B1 (en) 2009-11-24 2018-06-27 BASF Plant Science Company GmbH Novel fatty acid desaturase and uses thereof
CN101724637B (zh) * 2009-12-23 2011-10-26 南开大学 球等鞭金藻δ9延长酶的核苷酸序列及其应用
CA2804925A1 (en) 2010-06-25 2011-12-29 Basf Plant Science Company Gmbh Acyltransferases from thraustochytrium species and uses thereof in fatty acid production
JP5963749B2 (ja) 2010-08-26 2016-08-03 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニーＥ．Ｉ．Ｄｕ Ｐｏｎｔ Ｄｅ Ｎｅｍｏｕｒｓ Ａｎｄ Ｃｏｍｐａｎｙ 変異δ９エロンガーゼおよび多価不飽和脂肪酸の製造におけるそれらの使用
US8703473B2 (en) 2010-08-26 2014-04-22 E I Du Pont De Nemours And Company Recombinant microbial host cells for high eicosapentaenoic acid production
US9458477B2 (en) 2010-10-21 2016-10-04 Basf Plant Science Company Gmbh Fatty acid desaturases, elongases, elongation components and uses thereof
UA127917C2 (uk) 2012-06-15 2024-02-14 Коммонвелт Сайнтіфік Енд Індастріел Рісерч Організейшн Рекомбінантна клітина brassica napus, яка містить довголанцюгові поліненасичені жирні кислоти, трансгенна рослина та насіння brassica napus, спосіб отримання екстрагованого ліпіду рослин, харчового продукту та етилового ефіру поліненасичених жирних кислот
EP2880050B1 (en) 2012-08-03 2018-07-04 BASF Plant Science Company GmbH Novel enzymes, enzyme components and uses thereof
MX2016000225A (es) 2013-07-05 2016-06-15 Basf Plant Science Co Gmbh Elementos potenciadores de la expresion o actividad genica.
US9725399B2 (en) 2013-12-18 2017-08-08 Commonwealth Scientific And Industrial Research Organisation Lipid comprising long chain polyunsaturated fatty acids
KR102527795B1 (ko) 2014-06-27 2023-05-02 커먼웰쓰 사이언티픽 앤 인더스트리알 리서치 오거니제이션 도코사펜타에노산을 포함하는 지질
FR3053052B1 (fr) * 2016-06-28 2021-02-12 Fermentalg Microalgue modifiee pour une production enrichie en tag
CN110506676B (zh) * 2019-08-23 2022-03-08 上海海洋大学 Elovl1基因及其应用

Family Cites Families (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5352605A (en) 1983-01-17 1994-10-04 Monsanto Company Chimeric genes for transforming plant cells using viral promoters
EP0131623B2 (en) 1983-01-17 1999-07-28 Monsanto Company Chimeric genes suitable for expression in plant cells
US5504200A (en) 1983-04-15 1996-04-02 Mycogen Plant Science, Inc. Plant gene expression
US5420034A (en) 1986-07-31 1995-05-30 Calgene, Inc. Seed-specific transcriptional regulation
JP2874751B2 (ja) 1986-04-09 1999-03-24 ジェンザイム・コーポレーション 希望する蛋白質をミルク中へ分泌する遺伝子移植動物
US4962028A (en) 1986-07-09 1990-10-09 Dna Plant Technology Corporation Plant promotors
US5116742A (en) 1986-12-03 1992-05-26 University Patents, Inc. RNA ribozyme restriction endoribonucleases and methods
US4987071A (en) 1986-12-03 1991-01-22 University Patents, Inc. RNA ribozyme polymerases, dephosphorylases, restriction endoribonucleases and methods
US4873316A (en) 1987-06-23 1989-10-10 Biogen, Inc. Isolation of exogenous recombinant proteins from the milk of transgenic mammals
EP0397687B1 (en) 1987-12-21 1994-05-11 The University Of Toledo Agrobacterium mediated transformation of germinating plant seeds
US4934293A (en) 1987-12-28 1990-06-19 Pegasus Sewing Machine Mfg., Co., Ltd. Chaining thread sew-in device
US5614395A (en) 1988-03-08 1997-03-25 Ciba-Geigy Corporation Chemically regulatable and anti-pathogenic DNA sequences and uses thereof
DE3843628A1 (de) 1988-12-21 1990-07-05 Inst Genbiologische Forschung Wundinduzierbare und kartoffelknollenspezifische transkriptionale regulation
US5364780A (en) 1989-03-17 1994-11-15 E. I. Du Pont De Nemours And Company External regulation of gene expression by inducible promoters
ES2163392T3 (es) 1990-03-16 2002-02-01 Calgene Llc Nuevas secuencias expresadas preferentemente en el desarrollo de semillas precoces, y procedimientos relacionados con las mismas.
US5187267A (en) 1990-06-19 1993-02-16 Calgene, Inc. Plant proteins, promoters, coding sequences and use
US5475099A (en) 1990-08-15 1995-12-12 Calgene Inc. Plant fatty acid synthases
DE69331055T2 (de) 1992-04-13 2002-06-20 Syngenta Ltd., Haselmere Dna-konstruktionen und diese enthaltende pflanzen
GB9324707D0 (en) 1993-12-02 1994-01-19 Olsen Odd Arne Promoter
US5576198A (en) 1993-12-14 1996-11-19 Calgene, Inc. Controlled expression of transgenic constructs in plant plastids
NZ277562A (en) 1993-12-28 1997-12-19 Kirin Brewery Gene encoding a protein that desaturates lipid bound fatty acids at the delta 9 position
GB9403512D0 (en) 1994-02-24 1994-04-13 Olsen Odd Arne Promoter
GEP20012558B (en) 1995-08-10 2001-10-25 Rutgers Univ Nuclear-Encoded Transcription System in Plastids of Higher Plants
US5850026A (en) 1996-07-03 1998-12-15 Cargill, Incorporated Canola oil having increased oleic acid and decreased linolenic acid content
JP2781783B2 (ja) 1996-07-30 1998-07-30 山形日本電気株式会社 半導体装置用パッケージ
WO1998013487A1 (en) 1996-09-27 1998-04-02 Maxygen, Inc. Methods for optimization of gene therapy by recursive sequence shuffling and selection
US5977436A (en) 1997-04-09 1999-11-02 Rhone Poulenc Agrochimie Oleosin 5' regulatory region for the modification of plant seed lipid composition
WO1998046764A1 (en) 1997-04-11 1998-10-22 Calgene Llc Methods and compositions for synthesis of long chain polyunsaturated fatty acids in plants
US5972664A (en) 1997-04-11 1999-10-26 Abbott Laboratories Methods and compositions for synthesis of long chain poly-unsaturated fatty acids
AR013633A1 (es) 1997-04-11 2001-01-10 Calgene Llc METODO PARA LA ALTERACIoN DE LA COMPOSICIoN DE ÁCIDOS GRASOS DE CADENA MEDIA EN SEMILLAS VEGETALES QUE EXPRESAN UNA TIOESTERASA QUE PREFIERE CADENA MEDIA VEGETAL HETERoLOGA.
US6051754A (en) 1997-04-11 2000-04-18 Abbott Laboratories Methods and compositions for synthesis of long chain poly-unsaturated fatty acids in plants
JP2002510205A (ja) * 1997-06-04 2002-04-02 カルジーン エルエルシー ポリケチド様合成遺伝子を植物内で発現させることによる多不飽和脂肪酸の製造
ATE346944T1 (de) 1997-09-30 2006-12-15 Univ California Herstellung von proteinen in pflanzensamen
EE200000372A (et) 1997-12-23 2001-12-17 University Of Bristol Desaturaas
EP1062351B1 (en) 1998-03-11 2006-05-10 Syngenta Participations AG Novel plant plastid promoter sequence
WO1999064616A2 (en) 1998-06-12 1999-12-16 Abbott Laboratories Polyunsaturated fatty acids in plants
US6677145B2 (en) * 1998-09-02 2004-01-13 Abbott Laboratories Elongase genes and uses thereof
US6403349B1 (en) * 1998-09-02 2002-06-11 Abbott Laboratories Elongase gene and uses thereof
CA2791961A1 (en) 1998-12-07 2000-06-15 Washington State University Research Foundation Desaturases and methods of using them for synthesis of polyunsaturated fatty acids
AU3308500A (en) 1999-03-18 2000-10-04 University Of Bristol, The Polysaturated fatty acid (pufa) elongase from caenorhabditis elegans
KR20020073580A (ko) * 2000-02-09 2002-09-27 바스프 악티엔게젤샤프트 신규 연장효소 유전자 및 다가불포화 지방산의 제조 방법
ES2534637T3 (es) 2005-08-17 2015-04-27 Glaxosmithkline Biologicals S.A. Vacuna de rotavirus que induce protección cruzada heterotípica

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WO2002077213A2 (en) 2002-10-03
US7601889B2 (en) 2009-10-13
DK1373519T3 (da) 2011-04-18
ES2383451T3 (es) 2012-06-21
IL157562A0 (en) 2004-03-28
EE200300471A (et) 2003-12-15
JP2004531248A (ja) 2004-10-14
CA2442010C (en) 2013-07-30
CA2442010A1 (en) 2002-10-03
WO2002077213A3 (en) 2003-03-13
EP1373519B1 (en) 2010-12-22
GB0107510D0 (en) 2001-05-16
NO20034276L (no) 2003-10-22
EP1373519A2 (en) 2004-01-02
AR033449A1 (es) 2003-12-17
CN1537166A (zh) 2004-10-13
US20050089981A1 (en) 2005-04-28
DE60238669D1 (de) 2011-02-03
NO20034276D0 (no) 2003-09-25
ATE492641T1 (de) 2011-01-15
AU2002310891B2 (en) 2008-01-24

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