DE60238669D1 - Neues elongasegen und verfahren zur herstellung von delta-9-polyunsättigten fettsäuren - Google Patents
Neues elongasegen und verfahren zur herstellung von delta-9-polyunsättigten fettsäurenInfo
- Publication number
- DE60238669D1 DE60238669D1 DE60238669T DE60238669T DE60238669D1 DE 60238669 D1 DE60238669 D1 DE 60238669D1 DE 60238669 T DE60238669 T DE 60238669T DE 60238669 T DE60238669 T DE 60238669T DE 60238669 D1 DE60238669 D1 DE 60238669D1
- Authority
- DE
- Germany
- Prior art keywords
- polyunated
- delta
- production
- fatty acids
- elongases
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 235000014113 dietary fatty acids Nutrition 0.000 title 1
- 229930195729 fatty acid Natural products 0.000 title 1
- 239000000194 fatty acid Substances 0.000 title 1
- 150000004665 fatty acids Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
- C12N15/8247—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
- C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Nutrition Science (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Enzymes And Modification Thereof (AREA)
- Peptides Or Proteins (AREA)
- Fodder In General (AREA)
- Edible Oils And Fats (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0107510.0A GB0107510D0 (en) | 2001-03-26 | 2001-03-26 | New elongase gene and a process for the production of -9-polyunsaturated fatty acids |
PCT/EP2002/003418 WO2002077213A2 (en) | 2001-03-26 | 2002-03-26 | New elongase gene and production of δ9-polyunsaturated fatty acids |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60238669D1 true DE60238669D1 (de) | 2011-02-03 |
Family
ID=9911561
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60238669T Expired - Lifetime DE60238669D1 (de) | 2001-03-26 | 2002-03-26 | Neues elongasegen und verfahren zur herstellung von delta-9-polyunsättigten fettsäuren |
Country Status (17)
Country | Link |
---|---|
US (1) | US7601889B2 (de) |
EP (1) | EP1373519B1 (de) |
JP (1) | JP2004531248A (de) |
CN (1) | CN1537166A (de) |
AR (1) | AR033449A1 (de) |
AT (1) | ATE492641T1 (de) |
AU (1) | AU2002310891B2 (de) |
BR (1) | BR0208202A (de) |
CA (1) | CA2442010C (de) |
DE (1) | DE60238669D1 (de) |
DK (1) | DK1373519T3 (de) |
EE (1) | EE200300471A (de) |
ES (1) | ES2383451T3 (de) |
GB (1) | GB0107510D0 (de) |
IL (1) | IL157562A0 (de) |
NO (1) | NO20034276L (de) |
WO (1) | WO2002077213A2 (de) |
Families Citing this family (59)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE452198T1 (de) * | 2002-01-30 | 2010-01-15 | Basf Plant Science Gmbh | Verfahren zur herstellung mehrfach ungesättigter fettsäuren mittels eines neuen elongase-gens |
EP1576166B1 (de) | 2002-12-19 | 2014-10-15 | University Of Bristol | Verfahren zur herstellung von mehrfach ungesättigten fettsäuren |
GB0229578D0 (en) * | 2002-12-19 | 2003-01-22 | Univ Bristol | Novel method for the production of polyunsaturated fatty acids |
US20040172682A1 (en) * | 2003-02-12 | 2004-09-02 | Kinney Anthony J. | Production of very long chain polyunsaturated fatty acids in oilseed plants |
JP4685762B2 (ja) * | 2003-03-12 | 2011-05-18 | ネステク ソシエテ アノニム | 食事制限のための膨化ペットフード |
US11952581B2 (en) | 2003-08-01 | 2024-04-09 | Basf Plant Science Gmbh | Process for the production of polyunsaturated fatty acids in transgenic organisms |
MX347962B (es) | 2003-08-01 | 2017-05-19 | Basf Plant Science Gmbh * | Metodo para la produccion de acidos grasos poli-insaturados en organismos transgenicos. |
ES2421440T3 (es) | 2004-02-27 | 2013-09-02 | Basf Plant Science Gmbh | Método para preparar ácidos grasos poliinsaturados en plantas transgénicas |
AU2005217080B2 (en) | 2004-02-27 | 2011-02-24 | Basf Plant Science Gmbh | Method for producing unsaturated omega-3 fatty acids in transgenic organisms |
ES2529572T3 (es) | 2004-04-22 | 2015-02-23 | Commonwealth Scientific And Industrial Research Organisation | Síntesis de ácidos grasos poliinsaturados de cadena larga por células recombinantes |
CA2563875C (en) | 2004-04-22 | 2015-06-30 | Commonwealth Scientific And Industrial Research Organisation | Synthesis of long-chain polyunsaturated fatty acids by recombinant cells |
PL1766023T3 (pl) | 2004-06-04 | 2011-04-29 | Fluxome Sciences As | Metabolicznie zmodyfikowane komórki do wytwarzania wielonienasyconych kwasów tłuszczowych |
US7256033B2 (en) | 2004-06-25 | 2007-08-14 | E. I. Du Pont De Nemours And Company | Delta-8 desaturase and its use in making polyunsaturated fatty acids |
US7588931B2 (en) | 2004-11-04 | 2009-09-15 | E. I. Du Pont De Nemours And Company | High arachidonic acid producing strains of Yarrowia lipolytica |
DE102005013779A1 (de) | 2005-03-22 | 2006-09-28 | Basf Plant Science Gmbh | Verfahren zur Herstellung von mehrfach ungesättigten C20- und C22-Fettsäuren mit mindestens vier Doppelbindungen in transgenen Pflanzen |
DE102005038036A1 (de) | 2005-08-09 | 2007-02-15 | Basf Plant Science Gmbh | Verfahren zur Herstellung von Arachidonsäure und/oder Eicosapentaensäure in transgenen Nutzpflanzen |
JP5123861B2 (ja) | 2005-11-23 | 2013-01-23 | イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー | Δ9エロンガーゼおよびそれらの多価不飽和脂肪酸製造における使用 |
GB0603160D0 (en) | 2006-02-16 | 2006-03-29 | Rothamsted Res Ltd | Nucleic acid |
AR059376A1 (es) | 2006-02-21 | 2008-03-26 | Basf Plant Science Gmbh | Procedimiento para la produccion de acidos grasos poliinsaturados |
US7943823B2 (en) | 2006-04-28 | 2011-05-17 | E.I. Du Pont De Nemours And Company | Delta-8 desaturase and its use in making polyunsaturated fatty acids |
US7695950B2 (en) | 2006-05-17 | 2010-04-13 | E. I. Du Pont De Nemours And Company | Δ5 desaturase and its use in making polyunsaturated fatty acids |
US7678560B2 (en) | 2006-05-17 | 2010-03-16 | E.I. Du Pont De Nemours And Company | Δ 5 desaturase and its use in making polyunsaturated fatty acids |
CN101578363A (zh) | 2006-08-29 | 2009-11-11 | 联邦科学技术研究组织 | 脂肪酸的合成 |
US8710299B2 (en) | 2006-10-06 | 2014-04-29 | Basf Plant Science Gmbh | Processes for producing polyunsaturated fatty acids in transgenic organisms |
US20110016581A1 (en) | 2006-10-23 | 2011-01-20 | E.I. Du Pont De Nemours And Company | Delta-8 desaturases and their use in making polyunsaturated fatty acids |
US8916361B2 (en) | 2006-11-17 | 2014-12-23 | Abbott Laboratories | Elongase gene and uses thereof |
US20080125487A1 (en) * | 2006-11-17 | 2008-05-29 | Tapas Das | Elongase gene and uses thereof |
BRPI0806354A2 (pt) | 2007-02-12 | 2011-09-06 | Du Pont | plantas oleaginosas transgências, sementes, óleos, produtos alimentìcios ou análogos a alimento, produtos alimentìcios medicinais ou análogos alimentìcios medicinais, produtos farmacêuticos, bebidas fórmulas para bebês, suplementos nutricionais, rações para animais domésticos, alimentos para aquacultura, rações animais, produtos de sementes inteiras, produtos de óleos misturados, produtos, subprodutos e subprodutos parcialmente processados |
JP5083941B2 (ja) * | 2007-03-07 | 2012-11-28 | 学校法人北里研究所 | 食用動物の肥育仕上がり判定方法 |
EP2126096B1 (de) | 2007-03-09 | 2013-12-18 | Monsanto Technology, LLC | Verfahren zur Pflanzentransformation mittels Spectinomycin-Selektion |
RS20090413A (en) | 2007-04-03 | 2010-06-30 | E. I. Du Pont De Nemours And Company | Multizymes and their use in making polyunsaturated fatty acids |
US8188338B2 (en) | 2007-04-10 | 2012-05-29 | E. I. Du Pont De Nemours And Company | Delta-8 desaturases and their use in making polyunsaturated fatty acids |
US8119860B2 (en) | 2007-04-16 | 2012-02-21 | E. I. Du Pont De Nemours And Company | Delta-9 elongases and their use in making polyunsaturated fatty acids |
US8957280B2 (en) | 2007-05-03 | 2015-02-17 | E. I. Du Pont De Nemours And Company | Delta-5 desaturases and their use in making polyunsaturated fatty acids |
CN101820757A (zh) | 2007-06-01 | 2010-09-01 | 普林斯顿大学托管委员会 | 通过调节宿主细胞代谢途径治疗病毒感染 |
CA2695112A1 (en) | 2007-07-31 | 2009-02-05 | Basf Plant Science Gmbh | Elongases and processes for the production of polyunsaturated fatty acids in transgenic organisms |
WO2009097331A1 (en) * | 2008-01-28 | 2009-08-06 | The Board Of Regents Of The University Of Oklahoma | Very long chain polyunsaturated fatty acids, methods of production, and uses |
US8168858B2 (en) | 2008-06-20 | 2012-05-01 | E. I. Du Pont De Nemours And Company | Delta-9 fatty acid elongase genes and their use in making polyunsaturated fatty acids |
EP2310512A1 (de) * | 2008-06-27 | 2011-04-20 | Institute National de la Recherche Agronomique | Rekombinante zellen und pflanzen zur synthese sehr langkettiger fettsäure (vlcfa) |
AU2009286755B2 (en) | 2008-08-26 | 2015-10-22 | Basf Plant Science Gmbh | Nucleic acids encoding desaturases and modified plant oil |
US8809559B2 (en) | 2008-11-18 | 2014-08-19 | Commonwelath Scientific And Industrial Research Organisation | Enzymes and methods for producing omega-3 fatty acids |
CA2760326A1 (en) | 2009-05-13 | 2010-11-18 | Basf Plant Science Company Gmbh | Acyltransferases and uses thereof in fatty acid production |
DE112010002353T5 (de) | 2009-06-08 | 2012-08-09 | Basf Plant Science Company Gmbh | Neue fettsäure-elongations-komponenten und anwenduingen davon |
DE112010002967T5 (de) | 2009-07-17 | 2012-10-11 | Basf Plant Science Company Gmbh | Neue Fettsäuredesaturasen und -elongasen und Anwendungen davon |
CN102597245A (zh) | 2009-08-31 | 2012-07-18 | 巴斯夫植物科学有限公司 | 用于在植物中增强种子特异性基因表达而促进增强的多不饱和脂肪酸合成的调节性核酸分子 |
US9347049B2 (en) | 2009-11-24 | 2016-05-24 | Basf Plant Science Company Gmbh | Fatty acid elongase and uses thereof |
EP2504427B1 (de) | 2009-11-24 | 2018-06-27 | BASF Plant Science Company GmbH | Neuartige fettsäuredesaturase und ihre verwendung |
CN101724637B (zh) * | 2009-12-23 | 2011-10-26 | 南开大学 | 球等鞭金藻δ9延长酶的核苷酸序列及其应用 |
NO2585603T3 (de) | 2010-06-25 | 2018-05-19 | ||
BR112013004356A2 (pt) | 2010-08-26 | 2017-06-27 | Du Pont | polinucleotídeo isolado, polipeptídeo mutante, constructo recombinante, célula transformada, método para produção de um ácido graxo poli-insaturado, óleo microbiano e célula hospedeira microbiana recombinante. |
CN103249834B (zh) | 2010-08-26 | 2016-10-26 | 纳幕尔杜邦公司 | 生产高水平二十碳五烯酸的重组微生物宿主细胞 |
WO2012052468A2 (en) | 2010-10-21 | 2012-04-26 | Basf Plant Science Company Gmbh | Novel fatty acid desaturases, elongases, elongation components and uses therof |
PL2861059T3 (pl) | 2012-06-15 | 2017-10-31 | Commw Scient Ind Res Org | Wytwarzanie długołańcuchowych wielonienasyconych kwasów tłuszczowych w komórkach roślinnych |
WO2014020533A2 (en) | 2012-08-03 | 2014-02-06 | Basf Plant Science Company Gmbh | Novel enzymes, enzyme components and uses thereof |
US10731169B2 (en) | 2013-07-05 | 2020-08-04 | Basf Plant Science Company Gmbh | Gene expression or activity enhancing elements |
KR102535223B1 (ko) | 2013-12-18 | 2023-05-30 | 커먼웰쓰 사이언티픽 앤 인더스트리알 리서치 오거니제이션 | 장쇄 다중불포화 지방산을 포함하는 지질 |
CN105219789B (zh) | 2014-06-27 | 2023-04-07 | 联邦科学技术研究组织 | 包含二十二碳五烯酸的提取的植物脂质 |
FR3053052B1 (fr) * | 2016-06-28 | 2021-02-12 | Fermentalg | Microalgue modifiee pour une production enrichie en tag |
CN110506676B (zh) * | 2019-08-23 | 2022-03-08 | 上海海洋大学 | Elovl1基因及其应用 |
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-
2001
- 2001-03-26 GB GBGB0107510.0A patent/GB0107510D0/en not_active Ceased
-
2002
- 2002-03-26 JP JP2002576656A patent/JP2004531248A/ja active Pending
- 2002-03-26 WO PCT/EP2002/003418 patent/WO2002077213A2/en active Application Filing
- 2002-03-26 CN CNA028073452A patent/CN1537166A/zh active Pending
- 2002-03-26 US US10/472,321 patent/US7601889B2/en not_active Expired - Fee Related
- 2002-03-26 BR BR0208202-0A patent/BR0208202A/pt not_active Application Discontinuation
- 2002-03-26 EP EP02735183A patent/EP1373519B1/de not_active Expired - Lifetime
- 2002-03-26 IL IL15756202A patent/IL157562A0/xx unknown
- 2002-03-26 AR ARP020101099A patent/AR033449A1/es active IP Right Grant
- 2002-03-26 DE DE60238669T patent/DE60238669D1/de not_active Expired - Lifetime
- 2002-03-26 AU AU2002310891A patent/AU2002310891B2/en not_active Ceased
- 2002-03-26 DK DK02735183.2T patent/DK1373519T3/da active
- 2002-03-26 ES ES02735183T patent/ES2383451T3/es not_active Expired - Lifetime
- 2002-03-26 CA CA2442010A patent/CA2442010C/en not_active Expired - Fee Related
- 2002-03-26 EE EEP200300471A patent/EE200300471A/xx unknown
- 2002-03-26 AT AT02735183T patent/ATE492641T1/de not_active IP Right Cessation
-
2003
- 2003-09-25 NO NO20034276A patent/NO20034276L/no unknown
Also Published As
Publication number | Publication date |
---|---|
AR033449A1 (es) | 2003-12-17 |
GB0107510D0 (en) | 2001-05-16 |
CA2442010A1 (en) | 2002-10-03 |
NO20034276D0 (no) | 2003-09-25 |
EP1373519B1 (de) | 2010-12-22 |
US20050089981A1 (en) | 2005-04-28 |
CA2442010C (en) | 2013-07-30 |
US7601889B2 (en) | 2009-10-13 |
DK1373519T3 (da) | 2011-04-18 |
AU2002310891B2 (en) | 2008-01-24 |
WO2002077213A3 (en) | 2003-03-13 |
JP2004531248A (ja) | 2004-10-14 |
IL157562A0 (en) | 2004-03-28 |
NO20034276L (no) | 2003-10-22 |
CN1537166A (zh) | 2004-10-13 |
ES2383451T3 (es) | 2012-06-21 |
WO2002077213A2 (en) | 2002-10-03 |
EE200300471A (et) | 2003-12-15 |
ATE492641T1 (de) | 2011-01-15 |
EP1373519A2 (de) | 2004-01-02 |
BR0208202A (pt) | 2004-04-13 |
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