ATE402607T1 - Delta-4-desaturase-gene und ihre verwendung - Google Patents

Delta-4-desaturase-gene und ihre verwendung

Info

Publication number
ATE402607T1
ATE402607T1 AT02731579T AT02731579T ATE402607T1 AT E402607 T1 ATE402607 T1 AT E402607T1 AT 02731579 T AT02731579 T AT 02731579T AT 02731579 T AT02731579 T AT 02731579T AT E402607 T1 ATE402607 T1 AT E402607T1
Authority
AT
Austria
Prior art keywords
acid
desaturase
delta
delta4
conversion
Prior art date
Application number
AT02731579T
Other languages
English (en)
Inventor
Pradip Mukerji
Yung-Sheng Huang
Tapas Das
Jennifer Thurmond
Amanda LEONARD
Suzette Pereira
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26818584&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE402607(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US09/849,199 external-priority patent/US20030082754A1/en
Application filed by Abbott Lab filed Critical Abbott Lab
Application granted granted Critical
Publication of ATE402607T1 publication Critical patent/ATE402607T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C12N9/0083—Miscellaneous (1.14.99)
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS OR COOKING OILS
    • A23D9/00—Other edible oils or fats, e.g. shortenings or cooking oils
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/158—Fatty acids; Fats; Products containing oils or fats
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L7/00—Cereal-derived products; Malt products; Preparation or treatment thereof
    • A23L7/10—Cereal-derived products
    • A23L7/117—Flakes or other shapes of ready-to-eat type; Semi-finished or partly-finished products therefor
    • A23L7/126—Snacks or the like obtained by binding, shaping or compacting together cereal grains or cereal pieces, e.g. cereal bars
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L9/00—Puddings; Cream substitutes; Preparation or treatment thereof
    • A23L9/10—Puddings; Dry powder puddings
    • A23L9/12—Ready-to-eat liquid or semi-liquid desserts, e.g. puddings, not to be mixed with liquids, e.g. water, milk
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6434—Docosahexenoic acids [DHA]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
    • C12P7/6445—Glycerides
    • C12P7/6472—Glycerides containing polyunsaturated fatty acid [PUFA] residues, i.e. having two or more double bonds in their backbone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Polymers & Plastics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nutrition Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Animal Husbandry (AREA)
  • Molecular Biology (AREA)
  • Obesity (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Cosmetics (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
AT02731579T 2001-05-04 2002-05-02 Delta-4-desaturase-gene und ihre verwendung ATE402607T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/849,199 US20030082754A1 (en) 2001-05-04 2001-05-04 Delta4 - desaturase genes and uses thereof
US10/120,637 US7045683B2 (en) 2001-05-04 2002-04-11 Δ4-desaturase genes and uses thereof

Publications (1)

Publication Number Publication Date
ATE402607T1 true ATE402607T1 (de) 2008-08-15

Family

ID=26818584

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02731579T ATE402607T1 (de) 2001-05-04 2002-05-02 Delta-4-desaturase-gene und ihre verwendung

Country Status (9)

Country Link
US (4) US7045683B2 (de)
EP (1) EP1401259B1 (de)
JP (1) JP4173010B2 (de)
AT (1) ATE402607T1 (de)
AU (1) AU2002303551B2 (de)
CA (1) CA2446439C (de)
DE (1) DE60227951D1 (de)
ES (1) ES2310204T3 (de)
WO (1) WO2002090493A2 (de)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6566583B1 (en) * 1997-06-04 2003-05-20 Daniel Facciotti Schizochytrium PKS genes
GB0316629D0 (en) * 2003-07-16 2003-08-20 Univ York Transgenic cell
US20040172682A1 (en) * 2003-02-12 2004-09-02 Kinney Anthony J. Production of very long chain polyunsaturated fatty acids in oilseed plants
WO2004090123A2 (de) * 2003-04-08 2004-10-21 Basf Plant Science Gmbh Δ-4-desaturasen aus euglena gracilis, exprimierende pflanzen und pufa enthaltende öle
US7238482B2 (en) 2003-05-07 2007-07-03 E. I. Du Pont De Nemours And Company Production of polyunsaturated fatty acids in oleaginous yeasts
US7125672B2 (en) 2003-05-07 2006-10-24 E. I. Du Pont De Nemours And Company Codon-optimized genes for the production of polyunsaturated fatty acids in oleaginous yeasts
DK1654344T3 (en) 2003-08-01 2019-02-04 Basf Plant Science Gmbh PROCEDURE FOR MANUFACTURING MULTI-Saturated FAT ACIDS IN TRANSGENES
US11952581B2 (en) 2003-08-01 2024-04-09 Basf Plant Science Gmbh Process for the production of polyunsaturated fatty acids in transgenic organisms
US7659120B2 (en) 2003-11-12 2010-02-09 E. I. Du Pont De Nemours And Company Δ 15 desaturases suitable for altering levels of polyunsaturated fatty acids in oleaginous plants and yeast
EP2623584B1 (de) 2004-02-27 2019-04-10 BASF Plant Science GmbH Verfahren zur Herstellung mehrfach ungesättigter Fettsäuren in transgenen Pflanzen
CA2558726C (en) 2004-02-27 2017-11-07 Basf Plant Science Gmbh Method for producing unsaturated .omega.-3-fatty acids in transgenic organisms
EP2357244A3 (de) 2004-04-22 2011-11-23 Commonwealth Scientific and Industrial Research Organisation Synthese von langkettigen polyungesättigten Fettsäuren durch rekombinante Zellen
CN103451246B (zh) 2004-04-22 2018-02-16 联邦科学技术研究组织 用重组细胞合成长链多不饱和脂肪酸
JP4955540B2 (ja) 2004-06-04 2012-06-20 フラクスオーム サイエンセズ エイ／エス 多価不飽和脂肪酸生産のための代謝改変細胞
US7550286B2 (en) 2004-11-04 2009-06-23 E. I. Du Pont De Nemours And Company Docosahexaenoic acid producing strains of Yarrowia lipolytica
AU2006325040B2 (en) 2005-06-07 2012-04-19 Dsm Nutritional Products Ag Eukaryotic microorganisms for producing lipids and antioxidants
BRPI0613685A2 (pt) * 2005-07-20 2011-01-25 Avestha Gengraine Tech Pvt Ltd delta-6 dessaturase de thraustochytrid e seus usos
AR059376A1 (es) 2006-02-21 2008-03-26 Basf Plant Science Gmbh Procedimiento para la produccion de acidos grasos poliinsaturados
US7678560B2 (en) 2006-05-17 2010-03-16 E.I. Du Pont De Nemours And Company Δ 5 desaturase and its use in making polyunsaturated fatty acids
US7695950B2 (en) 2006-05-17 2010-04-13 E. I. Du Pont De Nemours And Company Δ5 desaturase and its use in making polyunsaturated fatty acids
CA2659603C (en) * 2006-08-01 2017-03-07 Ocean Nutrition Canada Limited Oil producing microbes and methods of modification thereof
RU2009111266A (ru) 2006-08-29 2010-10-10 Коммонвелт Сайентифик энд Индастриал Рисерч Организейшн (AU) Синтез жирных кислот
UA102063C2 (uk) 2007-02-12 2013-06-10 Е. І. Дю Пон Де Немур Енд Компані Трансгенна соєва рослина, що продукує арахідонову кислоту
DK2129777T3 (en) * 2007-04-03 2016-01-25 Du Pont MULTIZYMER AND USE THEREOF FOR THE PRODUCTION OF polyunsaturated fatty acids
US8119784B2 (en) * 2008-04-02 2012-02-21 E. I. Du Pont De Nemours And Company Delta-4 desaturase and its use in making polyunsaturated fatty acids
BRPI0921467B1 (pt) 2008-11-18 2021-12-14 Commonwealth Scientific And Industrial Research Organisation Processo para a produção de óleo compreendendo ácido eicosapentaenóico (epa), ácido docosapentaenóico (dpa) e ácido docosahexaenóico (dha)
US9493520B2 (en) * 2009-07-17 2016-11-15 Basf Plant Science Company Gmbh Fatty acid desaturases and elongases and uses thereof
NZ700897A (en) * 2010-06-24 2015-10-30 Dow Agrosciences Llc Lowering saturated fatty acid content of plant seeds
US20120252888A1 (en) 2011-03-29 2012-10-04 Palupa Medical Ltd. Compositions and Methods for Treating Neurologic Disorders
BR112014025265A2 (pt) 2012-04-12 2017-07-11 Rothamsted Res Ltd produção de ácidos graxos poli-insaturados ômega-3 de cadeia longa
WO2013185184A2 (en) 2012-06-15 2013-12-19 Commonwealth Scientific And Industrial Research Organisation Production of long chain polyunsaturated fatty acids in plant cells
GB201217524D0 (en) 2012-10-01 2012-11-14 Rothamsted Res Ltd Recombinant organisms
EP2970926B1 (de) 2013-03-13 2018-01-31 DSM Nutritional Products AG Manipulation von mikroorganismen
EP3082405A4 (de) 2013-12-18 2017-12-13 Commonwealth Scientific and Industrial Research Organisation Lipid mit langkettigen mehrfach ungesättigten fettsäuren
SG11201610596PA (en) 2014-06-27 2017-01-27 Commw Scient Ind Res Org Lipid comprising docosapentaenoic acid
DE102014223256A1 (de) * 2014-11-14 2016-05-19 Robert Bosch Gmbh Vorrichtung zur Öffnungssensierung einer Verpackung sowie Verfahren zur Herstellung der Vorrichtung
WO2018064181A1 (en) * 2016-09-27 2018-04-05 Porter Kenneth L Harvested bale wrapping material sheets

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8507058D0 (en) 1985-03-19 1985-04-24 Efamol Ltd Pharmaceutical & dietary compositions
GB8524275D0 (en) 1985-10-02 1985-11-06 Efamol Ltd Pharmaceutical & dietary compositions
GB8524276D0 (en) 1985-10-02 1985-11-06 Efamol Ltd Pharmaceutical & dietary compositions
US5340742A (en) 1988-09-07 1994-08-23 Omegatech Inc. Process for growing thraustochytrium and schizochytrium using non-chloride salts to produce a microfloral biomass having omega-3-highly unsaturated fatty acids
US5985348A (en) 1995-06-07 1999-11-16 Omegatech, Inc. Milk products having high concentrations of omega-3 highly unsaturated fatty acids
US5116871A (en) 1988-09-13 1992-05-26 Efamol Holdings Plc Fatty acid therapy and compositions for the treatment of myalgic encephalomyelitis
US5196198A (en) 1989-06-02 1993-03-23 Abbott Laboratories Parenteral nutrition product
DK0537178T4 (da) 1990-05-25 2007-07-16 Du Pont Nukleotidsekvens af sojabönne-stearoyl-ACP-desaturase-gen
PH31293A (en) 1991-10-10 1998-07-06 Rhone Poulenc Agrochimie Production of y-linolenic acid by a delta6-desaturage.
JPH07501701A (ja) 1991-12-04 1995-02-23 イー・アイ・デユポン・ドウ・ヌムール・アンド・カンパニー 植物由来の脂肪酸不飽和化酵素遺伝子
DE69333025T2 (de) 1992-11-17 2004-04-29 E.I. Du Pont De Nemours And Co., Wilmington Für mikrosom delta 12 fettsäuredesaturase kodierende gene und verwandte enzyme von pflanzen
JPH078215A (ja) 1993-04-30 1995-01-13 Kawasaki Steel Corp ドコサヘキサエン酸含有海洋性微細藻類食品素材およびその製造方法
WO1995024494A1 (en) 1994-03-09 1995-09-14 Abbott Laboratories Humanized milk
US5654402A (en) 1994-10-26 1997-08-05 Michigan State University Methods and compositions relating to plant Δ6 palmitoyl-acyl carrier protein desaturase
DE19629433A1 (de) 1996-07-22 1998-01-29 Hoechst Ag Omega-3-fettsäurenenthaltende Zubereitung aus Mikroorganismen als Prophylaktikum bzw. Therapeutikum gegen parasitäre Erkrankungen beim Tier
BR9808506A (pt) * 1997-04-11 2000-05-23 Calgene Llc Métodos e composições para sìntese de ácidos graxos poliinsaturados de cadeia longa em plantas
US6677145B2 (en) 1998-09-02 2004-01-13 Abbott Laboratories Elongase genes and uses thereof
US6403349B1 (en) 1998-09-02 2002-06-11 Abbott Laboratories Elongase gene and uses thereof
KR19990046733A (ko) 1999-04-20 1999-07-05 류성구 미생물슈도모나스에의한도코사핵사노인산(ｄｈａ)의제조방법
WO2001004636A1 (en) * 1999-07-12 2001-01-18 Ohio University Mammalian cells expressing desaturases and elongases
EP1911837B1 (de) 2000-09-28 2011-05-25 Bioriginal Food & Science Corp. FAD5-2, Mitglied der Desaturase-Familie und Verwendungen davon
EP1392823B1 (de) * 2001-01-25 2011-11-30 Abbott Laboratories Modifiziertes insulin mit reduzierter immunogenität

Also Published As

Publication number Publication date
US7220897B2 (en) 2007-05-22
WO2002090493A3 (en) 2003-10-16
JP4173010B2 (ja) 2008-10-29
EP1401259A4 (de) 2005-06-22
CA2446439C (en) 2012-06-05
US20050005328A1 (en) 2005-01-06
US7045683B2 (en) 2006-05-16
JP2005525780A (ja) 2005-09-02
EP1401259A2 (de) 2004-03-31
CA2446439A1 (en) 2002-11-14
US20030134400A1 (en) 2003-07-17
EP1401259B1 (de) 2008-07-30
US20050005329A1 (en) 2005-01-06
US7205134B2 (en) 2007-04-17
DE60227951D1 (de) 2008-09-11
AU2002303551B2 (en) 2007-06-14
WO2002090493A2 (en) 2002-11-14
ES2310204T3 (es) 2009-01-01
US20050003442A1 (en) 2005-01-06
AU2002303551B8 (en) 2002-11-18
US7208297B2 (en) 2007-04-24

Similar Documents

Publication Publication Date Title
ATE402607T1 (de) Delta-4-desaturase-gene und ihre verwendung
CY1106085T1 (el) Το ανθρωπινο γονιδιο της δελτα-5δεσατουρασης και οι χρησεις του
WO2002081668A3 (en) Desaturase genes and uses thereof
WO2000012720A3 (en) Elongase genes and uses thereof
ATE350028T1 (de) Konjugierte linolsäurezusammensetzung
ATE200619T1 (de) Mikrobielle öle und ihre verwendungen
WO2003102138A3 (en) Elongase genes and uses thereof
ATE402944T1 (de) Desaturasegene, von diesen codierte enzyme und verwendungen dafür
EA200870001A1 (ru) Гидролизат биомассы, его применение и производство
DE60235259D1 (de) Funktionelle acylglyceride
NO994924L (no) Fremgangsmåter og blandinger for syntese av langkjedede flerumettede fettsyrer
NO20043592L (no) Nytt elongasegen og fremgangsmate for fremstilling av flerumettede fettsyrer
MXPA04006803A (es) Derivados de acidos alfa-feniltiocarboxilicos y alfa-feniloxi-carboxilicos para tratamiento de enfermedades que responden a activacion del receptor alfa activado del proliferador de peroxisoma.
NO20071180L (no) Delta 6-desaturase-gener og anvendelser derav
DE69809743D1 (de) An omega-3 ungesättigten fettsäuren angereicherte wachsester, ihre herstellung und verwendung
ATE437894T1 (de) Isoliertes gum-operon aus xyllela fastidiosa, isolierte nukleinsäuremoleküle und deren verwendungen
BG105618A (en) Beta-amido and beta-sulphonamide derivatives of carboxylic acids, method for preparation and application as endothelin-receptor antagonists
MD1328G2 (ro) Mediu nutritiv pentru cultivarea drojdiei Sporobolomyces peraroseus
BR0305926A (pt) Genes da delta-4-desaturase e seus usos
AR039898A1 (es) Genes de elongasas y usos de los mismos
TH51597A (th) วิธีการที่ถูกปรับปรุงของการรวมกรดไขมันไม่อิ่มตัวหลายตำแหน่งเข้าไว้ในนม

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties