AR029072A1 - Bis-(n,n'-bis-(2-haloetil)amino fosforamidatos, un procedimiento para su preparacion, una composicion farmaceutica, y el uso de los mismos para la manufactura de medicamentos antitumorales - Google Patents

Bis-(n,n'-bis-(2-haloetil)amino fosforamidatos, un procedimiento para su preparacion, una composicion farmaceutica, y el uso de los mismos para la manufactura de medicamentos antitumorales

Info

Publication number
AR029072A1
AR029072A1 ARP010102067A ARP010102067A AR029072A1 AR 029072 A1 AR029072 A1 AR 029072A1 AR P010102067 A ARP010102067 A AR P010102067A AR P010102067 A ARP010102067 A AR P010102067A AR 029072 A1 AR029072 A1 AR 029072A1
Authority
AR
Argentina
Prior art keywords
bis
haloethyl
manufacture
preparation
antitumural
Prior art date
Application number
ARP010102067A
Other languages
English (en)
Spanish (es)
Original Assignee
Telik Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Telik Inc filed Critical Telik Inc
Publication of AR029072A1 publication Critical patent/AR029072A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/22—Amides of acids of phosphorus
    • C07F9/24—Esteramides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/22—Amides of acids of phosphorus
    • C07F9/24—Esteramides
    • C07F9/2454—Esteramides the amide moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/2458—Esteramides the amide moiety containing a substituent or a structure which is considered as characteristic of aliphatic amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/22—Amides of acids of phosphorus
    • C07F9/24—Esteramides
    • C07F9/2404—Esteramides the ester moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/2408—Esteramides the ester moiety containing a substituent or a structure which is considered as characteristic of hydroxyalkyl compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ARP010102067A 2000-05-02 2001-05-02 Bis-(n,n'-bis-(2-haloetil)amino fosforamidatos, un procedimiento para su preparacion, una composicion farmaceutica, y el uso de los mismos para la manufactura de medicamentos antitumorales AR029072A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US56318100A 2000-05-02 2000-05-02

Publications (1)

Publication Number Publication Date
AR029072A1 true AR029072A1 (es) 2003-06-04

Family

ID=24249433

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP010102067A AR029072A1 (es) 2000-05-02 2001-05-02 Bis-(n,n'-bis-(2-haloetil)amino fosforamidatos, un procedimiento para su preparacion, una composicion farmaceutica, y el uso de los mismos para la manufactura de medicamentos antitumorales

Country Status (25)

Country Link
EP (2) EP1278759B1 (https=)
JP (1) JP4249928B2 (https=)
KR (1) KR100729980B1 (https=)
CN (1) CN1182143C (https=)
AR (1) AR029072A1 (https=)
AT (2) ATE313549T1 (https=)
AU (2) AU2001261153B2 (https=)
BR (1) BR0110553A (https=)
CA (1) CA2407606C (https=)
CZ (1) CZ20023615A3 (https=)
DE (2) DE60141181D1 (https=)
DK (2) DK1278759T3 (https=)
EA (1) EA006852B1 (https=)
ES (2) ES2337154T3 (https=)
HU (1) HUP0300688A3 (https=)
IL (2) IL152325A0 (https=)
MX (1) MXPA02010813A (https=)
NO (2) NO328854B1 (https=)
NZ (1) NZ522189A (https=)
PL (1) PL207005B1 (https=)
PT (1) PT1607399E (https=)
TW (1) TWI308569B (https=)
UA (1) UA74574C2 (https=)
WO (1) WO2001083496A1 (https=)
ZA (1) ZA200208591B (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200600091A (en) * 2004-05-21 2006-01-01 Telik Inc Sulfonylethyl phosphorodiamidates
US8198247B2 (en) 2004-12-21 2012-06-12 Telik, Inc. Process for and intermediates in the preparation of canfosfamide and its salts
US7655799B2 (en) 2006-11-29 2010-02-02 Telik, Inc. 2{[2-(substituted amino)ethyl]sulfonyl}ethyl N,N,N',N'-tetrakis(2-chloroethyl)phosphorodiamidates
US7872134B2 (en) 2007-12-12 2011-01-18 Telik, Inc. 2-{[2-(substituted amino)ethyl]sulfonyl}ethyl N,N-bis(2-chloroethyl)phosphorodiamidates
EP2260111B2 (en) * 2008-03-14 2022-03-23 Genentech, Inc. Genetic variations associated with drug resistance
WO2020228685A1 (zh) 2019-05-13 2020-11-19 深圳艾欣达伟医药科技有限公司 含氟化合物及抗癌医药用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5556942A (en) * 1991-04-29 1996-09-17 Terrapin Technologies, Inc. Glutathione S-transferase-activated compounds

Also Published As

Publication number Publication date
PL207005B1 (pl) 2010-10-29
JP4249928B2 (ja) 2009-04-08
ES2337154T3 (es) 2010-04-21
JP2003531913A (ja) 2003-10-28
AU6115301A (en) 2001-11-12
EA006852B1 (ru) 2006-04-28
DE60116081D1 (en) 2006-01-26
CN1427844A (zh) 2003-07-02
EP1278759A1 (en) 2003-01-29
NO20025240L (no) 2002-12-04
ZA200208591B (en) 2004-03-04
PT1607399E (pt) 2010-02-02
ATE313549T1 (de) 2006-01-15
NO331833B1 (no) 2012-04-16
UA74574C2 (en) 2006-01-16
HUP0300688A2 (hu) 2003-07-28
MXPA02010813A (es) 2004-02-26
WO2001083496A1 (en) 2001-11-08
EA200201154A1 (ru) 2003-04-24
ES2253380T3 (es) 2006-06-01
DE60141181D1 (de) 2010-03-11
AU2001261153B2 (en) 2005-04-07
KR20020094000A (ko) 2002-12-16
NO20025240D0 (no) 2002-11-01
KR100729980B1 (ko) 2007-06-20
CN1182143C (zh) 2004-12-29
DE60116081T2 (de) 2006-08-03
HK1050368A1 (en) 2003-06-20
EP1278759B1 (en) 2005-12-21
ATE455779T1 (de) 2010-02-15
IL152325A0 (en) 2003-05-29
DK1607399T3 (da) 2010-05-10
HUP0300688A3 (en) 2005-02-28
BR0110553A (pt) 2003-04-01
DK1278759T3 (da) 2006-02-13
NO20093371L (no) 2002-12-04
CA2407606A1 (en) 2001-11-08
IL152325A (en) 2011-04-28
HK1084119A1 (en) 2006-07-21
TWI308569B (en) 2009-04-11
NO328854B1 (no) 2010-05-31
PL358155A1 (en) 2004-08-09
CA2407606C (en) 2008-07-15
EP1607399A3 (en) 2006-01-04
EP1607399B1 (en) 2010-01-20
EP1607399A2 (en) 2005-12-21
CZ20023615A3 (cs) 2003-04-16
NZ522189A (en) 2004-04-30

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