AR011278A1 - Una composicion y un medicamento que comprenden derivados amino acidos y un factor neutrofico para estimular el crecimiento de neuritas en celulasnerviosas - Google Patents
Una composicion y un medicamento que comprenden derivados amino acidos y un factor neutrofico para estimular el crecimiento de neuritas en celulasnerviosasInfo
- Publication number
- AR011278A1 AR011278A1 ARP970105318A ARP970105318A AR011278A1 AR 011278 A1 AR011278 A1 AR 011278A1 AR P970105318 A ARP970105318 A AR P970105318A AR P970105318 A ARP970105318 A AR P970105318A AR 011278 A1 AR011278 A1 AR 011278A1
- Authority
- AR
- Argentina
- Prior art keywords
- branched
- straight
- alkyl
- alkenyl
- alkynyl
- Prior art date
Links
- 150000003862 amino acid derivatives Chemical class 0.000 title abstract 2
- 210000002241 neurite Anatomy 0.000 title abstract 2
- 210000002569 neuron Anatomy 0.000 title abstract 2
- 229940126601 medicinal product Drugs 0.000 title 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 6
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 5
- 125000003342 alkenyl group Chemical group 0.000 abstract 5
- -1 2-pyrazolinyl Chemical group 0.000 abstract 4
- 125000000304 alkynyl group Chemical group 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000000392 cycloalkenyl group Chemical group 0.000 abstract 2
- 125000004502 1,2,3-oxadiazolyl group Chemical group 0.000 abstract 1
- 125000004520 1,3,4-thiadiazolyl group Chemical group 0.000 abstract 1
- 125000003363 1,3,5-triazinyl group Chemical group N1=C(N=CN=C1)* 0.000 abstract 1
- 125000001637 1-naphthyl group Chemical group [H]C1=C([H])C([H])=C2C(*)=C([H])C([H])=C([H])C2=C1[H] 0.000 abstract 1
- YBYIRNPNPLQARY-UHFFFAOYSA-N 1H-indene Natural products C1=CC=C2CC=CC2=C1 YBYIRNPNPLQARY-UHFFFAOYSA-N 0.000 abstract 1
- 125000002941 2-furyl group Chemical group O1C([*])=C([H])C([H])=C1[H] 0.000 abstract 1
- 125000001622 2-naphthyl group Chemical group [H]C1=C([H])C([H])=C2C([H])=C(*)C([H])=C([H])C2=C1[H] 0.000 abstract 1
- 125000004105 2-pyridyl group Chemical group N1=C([*])C([H])=C([H])C([H])=C1[H] 0.000 abstract 1
- 125000000175 2-thienyl group Chemical group S1C([*])=C([H])C([H])=C1[H] 0.000 abstract 1
- 125000003682 3-furyl group Chemical group O1C([H])=C([*])C([H])=C1[H] 0.000 abstract 1
- 125000003349 3-pyridyl group Chemical group N1=C([H])C([*])=C([H])C([H])=C1[H] 0.000 abstract 1
- 125000001541 3-thienyl group Chemical group S1C([H])=C([*])C([H])=C1[H] 0.000 abstract 1
- 125000000339 4-pyridyl group Chemical group N1=C([H])C([H])=C([*])C([H])=C1[H] 0.000 abstract 1
- 125000003601 C2-C6 alkynyl group Chemical group 0.000 abstract 1
- 108010025020 Nerve Growth Factor Proteins 0.000 abstract 1
- 102000007072 Nerve Growth Factors Human genes 0.000 abstract 1
- 125000002178 anthracenyl group Chemical group C1(=CC=CC2=CC3=CC=CC=C3C=C12)* 0.000 abstract 1
- 125000003828 azulenyl group Chemical group 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000003983 fluorenyl group Chemical group C1(=CC=CC=2C3=CC=CC=C3CC12)* 0.000 abstract 1
- 125000002883 imidazolyl group Chemical group 0.000 abstract 1
- 125000003454 indenyl group Chemical group C1(C=CC2=CC=CC=C12)* 0.000 abstract 1
- 125000000842 isoxazolyl group Chemical group 0.000 abstract 1
- 230000000508 neurotrophic effect Effects 0.000 abstract 1
- 239000003900 neurotrophic factor Substances 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000002971 oxazolyl group Chemical group 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000003373 pyrazinyl group Chemical group 0.000 abstract 1
- 125000003072 pyrazolidinyl group Chemical group 0.000 abstract 1
- 125000003226 pyrazolyl group Chemical group 0.000 abstract 1
- 125000002098 pyridazinyl group Chemical group 0.000 abstract 1
- 125000000714 pyrimidinyl group Chemical group 0.000 abstract 1
- 125000000168 pyrrolyl group Chemical group 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 125000000335 thiazolyl group Chemical group 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/185—Nerve growth factor [NGF]; Brain derived neurotrophic factor [BDNF]; Ciliary neurotrophic factor [CNTF]; Glial derived neurotrophic factor [GDNF]; Neurotrophins, e.g. NT-3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Psychology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Urology & Nephrology (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/748,447 US5840736A (en) | 1996-11-13 | 1996-11-13 | Methods and compositions for stimulating neurite growth |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR011278A1 true AR011278A1 (es) | 2000-08-16 |
Family
ID=25009484
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP970105318A AR011278A1 (es) | 1996-11-13 | 1997-11-13 | Una composicion y un medicamento que comprenden derivados amino acidos y un factor neutrofico para estimular el crecimiento de neuritas en celulasnerviosas |
Country Status (32)
| Country | Link |
|---|---|
| US (3) | US5840736A (h) |
| EP (1) | EP0946190B1 (h) |
| JP (1) | JP2001504470A (h) |
| KR (1) | KR100544451B1 (h) |
| CN (1) | CN1168442C (h) |
| AP (1) | AP9901518A0 (h) |
| AR (1) | AR011278A1 (h) |
| AT (1) | ATE250424T1 (h) |
| AU (1) | AU724833B2 (h) |
| BG (1) | BG64670B1 (h) |
| BR (1) | BR9712765A (h) |
| CA (1) | CA2270634A1 (h) |
| CO (1) | CO4930260A1 (h) |
| CZ (1) | CZ296058B6 (h) |
| DE (1) | DE69725169T2 (h) |
| DK (1) | DK0946190T3 (h) |
| EA (1) | EA004247B1 (h) |
| ES (1) | ES2206753T3 (h) |
| HU (1) | HU226728B1 (h) |
| IL (1) | IL129555A (h) |
| IN (1) | IN183740B (h) |
| IS (1) | IS2057B (h) |
| NO (1) | NO328030B1 (h) |
| NZ (1) | NZ335394A (h) |
| PL (1) | PL190903B1 (h) |
| PT (1) | PT946190E (h) |
| SK (1) | SK284535B6 (h) |
| TR (1) | TR199901034T2 (h) |
| TW (1) | TW513302B (h) |
| UA (1) | UA63926C2 (h) |
| WO (1) | WO1998020891A1 (h) |
| ZA (1) | ZA9710256B (h) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5859031A (en) | 1995-06-07 | 1999-01-12 | Gpi Nil Holdings, Inc. | Small molecule inhibitors of rotamase enzyme activity |
| US5780484A (en) * | 1996-11-13 | 1998-07-14 | Vertex Pharmaceuticals Incorporated | Methods for stimulating neurite growth with piperidine compounds |
| US6242468B1 (en) | 1997-02-27 | 2001-06-05 | Jia-He Li | Carbamate and urea compositions and neurotrophic uses |
| US6514686B2 (en) | 1997-04-28 | 2003-02-04 | The University Of British Columbia | Method and composition for modulating amyloidosis |
| US5945441A (en) | 1997-06-04 | 1999-08-31 | Gpi Nil Holdings, Inc. | Pyrrolidine carboxylate hair revitalizing agents |
| US20010049381A1 (en) | 1997-06-04 | 2001-12-06 | Gpl Nil Holdings, Inc., | Pyrrolidine derivative hair growth compositions and uses |
| US6852496B1 (en) | 1997-08-12 | 2005-02-08 | Oregon Health And Science University | Methods of screening for agents that promote nerve cell growth |
| US5968921A (en) * | 1997-10-24 | 1999-10-19 | Orgegon Health Sciences University | Compositions and methods for promoting nerve regeneration |
| US6331537B1 (en) | 1998-06-03 | 2001-12-18 | Gpi Nil Holdings, Inc. | Carboxylic acids and carboxylic acid isosteres of N-heterocyclic compounds |
| IL140040A0 (en) | 1998-06-03 | 2002-02-10 | Guilford Pharm Inc | N-linked sulfonamides of n-heterocyclic carboxylic acids or carboxylic acid isosteres |
| EP1098897B1 (en) | 1998-07-17 | 2004-06-09 | Agouron Pharmaceuticals, Inc. | Compounds, compositions, and methods for stimulating neuronal growth and elongation |
| GB9815880D0 (en) | 1998-07-21 | 1998-09-16 | Pfizer Ltd | Heterocycles |
| US6218423B1 (en) | 1998-08-14 | 2001-04-17 | Gpi Nil Holdings, Inc. | Pyrrolidine derivatives for vision and memory disorders |
| US7338976B1 (en) | 1998-08-14 | 2008-03-04 | Gpi Nil Holdings, Inc. | Heterocyclic esters or amides for vision and memory disorders |
| US6395758B1 (en) | 1998-08-14 | 2002-05-28 | Gpi Nil Holdings, Inc. | Small molecule carbamates or ureas for vision and memory disorders |
| US6462072B1 (en) | 1998-09-21 | 2002-10-08 | Gpi Nil Holdings, Inc. | Cyclic ester or amide derivatives |
| US6300341B1 (en) | 1998-09-30 | 2001-10-09 | The Procter & Gamble Co. | 2-substituted heterocyclic sulfonamides |
| US6307049B1 (en) | 1998-09-30 | 2001-10-23 | The Procter & Gamble Co. | Heterocyclic 2-substituted ketoamides |
| US6228872B1 (en) | 1998-11-12 | 2001-05-08 | Bristol-Myers Squibb Company | Neurotrophic diamide and carbamate agents |
| WO2000033814A2 (en) * | 1998-12-09 | 2000-06-15 | Chiron Corporation | Method for administering agents to the central nervous system |
| EP1140844A1 (en) * | 1999-01-08 | 2001-10-10 | Vertex Pharmaceuticals Incorporated | Process for the formation of intermediates useful for the preparation of pharmaceuticals |
| JP2003503480A (ja) | 1999-07-06 | 2003-01-28 | バーテックス ファーマシューティカルズ インコーポレイテッド | ニューロン活性を有するｎ−ヘテロ環誘導体 |
| US6734211B1 (en) | 1999-07-09 | 2004-05-11 | Oregon Health & Sciences University | Compositions and methods for promoting nerve regeneration |
| AU6497200A (en) * | 1999-07-30 | 2001-02-19 | Vertex Pharmaceuticals Incorporated | Acyclic and cyclic amine derivatives |
| US6417189B1 (en) | 1999-11-12 | 2002-07-09 | Gpi Nil Holdings, Inc. | AZA compounds, pharmaceutical compositions and methods of use |
| US7253169B2 (en) | 1999-11-12 | 2007-08-07 | Gliamed, Inc. | Aza compounds, pharmaceutical compositions and methods of use |
| ES2269206T3 (es) * | 1999-11-12 | 2007-04-01 | Alcon, Inc. | Ligandos de neurofilina para tratar trastornos oculares. |
| US6818643B1 (en) | 1999-12-08 | 2004-11-16 | Bristol-Myers Squibb Company | Neurotrophic bicyclic diamides |
| US7060676B2 (en) | 1999-12-20 | 2006-06-13 | Trustees Of Tufts College | T. cruzi-derived neurotrophic agents and methods of use therefor |
| ATE319712T1 (de) | 1999-12-21 | 2006-03-15 | Mgi Gp Inc | Hydantoin derivate, pharmazeutische zusammensetzungen und verfahren zu ihrer verwendung |
| US6555573B2 (en) | 2000-12-21 | 2003-04-29 | The Quigley Corporation | Method and composition for the topical treatment of diabetic neuropathy |
| ATE554784T1 (de) * | 2001-05-25 | 2012-05-15 | Cornell Res Foundation Inc | Hochaffiner ligand für p75 neurotrophin-rezeptor |
| FR2825273B1 (fr) * | 2001-05-29 | 2006-11-24 | Oreal | Composition pour le traitement des signes cutanes du vieillissement |
| WO2002096420A2 (en) * | 2001-05-29 | 2002-12-05 | Guilford Pharmaceuticals Inc. | Method for treating nerve injury caused by surgery |
| US20030105027A1 (en) * | 2001-11-06 | 2003-06-05 | Rosenbloom Richard A. | Nutritional supplements and methods for prevention, reduction and treatment of radiation injury |
| US7435725B2 (en) * | 2001-11-06 | 2008-10-14 | The Quigly Corporation | Oral compositions and methods for prevention, reduction and treatment of radiation injury |
| US20030118536A1 (en) * | 2001-11-06 | 2003-06-26 | Rosenbloom Richard A. | Topical compositions and methods for treatment of adverse effects of ionizing radiation |
| AU2002363800A1 (en) * | 2001-11-13 | 2003-05-26 | Loi Tran | Therapeutic agent composition and method of use |
| US20100247483A1 (en) * | 2001-11-13 | 2010-09-30 | Tran Loi H | Therapeutic agent composition and method of use |
| US7232798B2 (en) | 2001-11-13 | 2007-06-19 | Tran Loi H | Neuroprotection and neuroegenisis by administering cyclic prolyl glycine |
| US7083813B2 (en) * | 2002-11-06 | 2006-08-01 | The Quigley Corporation | Methods for the treatment of peripheral neural and vascular ailments |
| US8841326B2 (en) | 2004-02-12 | 2014-09-23 | Stc.Unm | Therapeutic curcumin derivatives |
| EP1988923A1 (en) * | 2006-02-02 | 2008-11-12 | Rinat Neuroscience Corp. | Methods for treating unwanted weight loss or eating disorders by administering a trkb agonist |
| CA2637707A1 (en) * | 2006-02-02 | 2007-08-09 | Rinat Neuroscience Corporation | Methods for treating obesity by administering a trkb antagonist |
| CA2672750A1 (en) * | 2006-12-20 | 2008-07-03 | Rinat Neuroscience Corporation | Trkb agonists for treating autoimmune disorders |
| US20090018151A1 (en) * | 2007-02-23 | 2009-01-15 | Ezekiel Fink | Topical Treatment of Peripheral diabetic complications |
| US11090303B2 (en) | 2018-05-15 | 2021-08-17 | Lloyd Hung Loi Tran | Therapeutic agent composition and method of use, for treatment of mild congnitive impairment, depression, and psychological disorders |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5798355A (en) | 1995-06-07 | 1998-08-25 | Gpi Nil Holdings, Inc. | Inhibitors of rotamase enzyme activity |
| IL115685A (en) * | 1994-11-16 | 2000-08-31 | Vertex Pharma | Amino acid derivatives pharmaceutical compositions containing the same and processes for the preparation thereof |
| US5543423A (en) * | 1994-11-16 | 1996-08-06 | Vertex Pharmaceuticals, Incorporated | Amino acid derivatives with improved multi-drug resistance activity |
| US5614547A (en) * | 1995-06-07 | 1997-03-25 | Guilford Pharmaceuticals Inc. | Small molecule inhibitors of rotamase enzyme |
| US5859031A (en) * | 1995-06-07 | 1999-01-12 | Gpi Nil Holdings, Inc. | Small molecule inhibitors of rotamase enzyme activity |
| US5696135A (en) * | 1995-06-07 | 1997-12-09 | Gpi Nil Holdings, Inc. | Inhibitors of rotamase enzyme activity effective at stimulating neuronal growth |
| US6037370A (en) | 1995-06-08 | 2000-03-14 | Vertex Pharmaceuticals Incorporated | Methods and compositions for stimulating neurite growth |
| US5801197A (en) | 1995-10-31 | 1998-09-01 | Gpi Nil Holdings, Inc. | Rotamase enzyme activity inhibitors |
| US5811434A (en) * | 1996-11-13 | 1998-09-22 | Vertex Pharmacueticals Incorporated | Methods and compositions for stimulating neurite growth |
| US9604852B2 (en) * | 2012-09-28 | 2017-03-28 | Dic Corporation | α-alumina particles and method for manufacturing the same |
-
1996
- 1996-11-13 US US08/748,447 patent/US5840736A/en not_active Expired - Lifetime
-
1997
- 1997-11-13 CZ CZ0168399A patent/CZ296058B6/cs not_active IP Right Cessation
- 1997-11-13 UA UA99063268A patent/UA63926C2/uk unknown
- 1997-11-13 BR BR9712765-5A patent/BR9712765A/pt not_active IP Right Cessation
- 1997-11-13 SK SK628-99A patent/SK284535B6/sk not_active IP Right Cessation
- 1997-11-13 PT PT97947533T patent/PT946190E/pt unknown
- 1997-11-13 IL IL12955597A patent/IL129555A/xx not_active IP Right Cessation
- 1997-11-13 TW TW086116911A patent/TW513302B/zh not_active IP Right Cessation
- 1997-11-13 AU AU52589/98A patent/AU724833B2/en not_active Ceased
- 1997-11-13 IN IN2149CA1997 patent/IN183740B/en unknown
- 1997-11-13 PL PL333270A patent/PL190903B1/pl not_active IP Right Cessation
- 1997-11-13 CA CA002270634A patent/CA2270634A1/en not_active Abandoned
- 1997-11-13 TR TR1999/01034T patent/TR199901034T2/xx unknown
- 1997-11-13 EA EA199900464A patent/EA004247B1/ru not_active IP Right Cessation
- 1997-11-13 CN CNB971802467A patent/CN1168442C/zh not_active Expired - Fee Related
- 1997-11-13 KR KR1019997004186A patent/KR100544451B1/ko not_active Expired - Fee Related
- 1997-11-13 AP APAP/P/1999/001518A patent/AP9901518A0/en unknown
- 1997-11-13 DK DK97947533T patent/DK0946190T3/da active
- 1997-11-13 ES ES97947533T patent/ES2206753T3/es not_active Expired - Lifetime
- 1997-11-13 JP JP52286598A patent/JP2001504470A/ja active Pending
- 1997-11-13 CO CO97066755A patent/CO4930260A1/es unknown
- 1997-11-13 DE DE69725169T patent/DE69725169T2/de not_active Expired - Lifetime
- 1997-11-13 WO PCT/US1997/020866 patent/WO1998020891A1/en active IP Right Grant
- 1997-11-13 AR ARP970105318A patent/AR011278A1/es unknown
- 1997-11-13 NZ NZ335394A patent/NZ335394A/en unknown
- 1997-11-13 ZA ZA9710256A patent/ZA9710256B/xx unknown
- 1997-11-13 AT AT97947533T patent/ATE250424T1/de not_active IP Right Cessation
- 1997-11-13 EP EP97947533A patent/EP0946190B1/en not_active Expired - Lifetime
- 1997-11-13 HU HU0001219A patent/HU226728B1/hu not_active IP Right Cessation
-
1998
- 1998-11-23 US US09/198,175 patent/US6172086B1/en not_active Expired - Lifetime
-
1999
- 1999-04-21 IS IS5032A patent/IS2057B/is unknown
- 1999-05-03 NO NO19992138A patent/NO328030B1/no not_active IP Right Cessation
- 1999-05-25 BG BG103429A patent/BG64670B1/bg unknown
-
2000
- 2000-10-03 US US09/678,265 patent/US6284778B1/en not_active Expired - Lifetime
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