PT1098897E - Compostos composicoes e metodos para estimular o crescimento e a elongacao neuronal - Google Patents

Compostos composicoes e metodos para estimular o crescimento e a elongacao neuronal

Info

Publication number
PT1098897E
PT1098897E PT99934043T PT99934043T PT1098897E PT 1098897 E PT1098897 E PT 1098897E PT 99934043 T PT99934043 T PT 99934043T PT 99934043 T PT99934043 T PT 99934043T PT 1098897 E PT1098897 E PT 1098897E
Authority
PT
Portugal
Prior art keywords
compositions
methods
stimulating growth
neuronal
elongation
Prior art date
Application number
PT99934043T
Other languages
English (en)
Inventor
Susumu Katoh
Hiroshi Kawakami
Hiroki Tada
Maria Angelica Linton
Vincent Kalish
John Howard Tatlock
J Ernest Villafranca
Original Assignee
Agouron Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agouron Pharma filed Critical Agouron Pharma
Publication of PT1098897E publication Critical patent/PT1098897E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
PT99934043T 1998-07-17 1999-07-15 Compostos composicoes e metodos para estimular o crescimento e a elongacao neuronal PT1098897E (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9329998P 1998-07-17 1998-07-17
US13288499P 1999-05-06 1999-05-06

Publications (1)

Publication Number Publication Date
PT1098897E true PT1098897E (pt) 2004-10-29

Family

ID=26787372

Family Applications (1)

Application Number Title Priority Date Filing Date
PT99934043T PT1098897E (pt) 1998-07-17 1999-07-15 Compostos composicoes e metodos para estimular o crescimento e a elongacao neuronal

Country Status (35)

Country Link
US (1) US6630472B1 (pt)
EP (1) EP1098897B1 (pt)
JP (1) JP2002520413A (pt)
KR (1) KR20010071920A (pt)
CN (1) CN1318067A (pt)
AP (1) AP2001002052A0 (pt)
AT (1) ATE268772T1 (pt)
AU (1) AU756912B2 (pt)
BG (1) BG105268A (pt)
BR (1) BR9912423A (pt)
CA (1) CA2337377A1 (pt)
DE (1) DE69917907T2 (pt)
DK (1) DK1098897T3 (pt)
EA (1) EA200100149A1 (pt)
EE (1) EE200100032A (pt)
ES (1) ES2226409T3 (pt)
GE (1) GEP20043368B (pt)
HR (1) HRP20010118A2 (pt)
HU (1) HUP0200637A3 (pt)
ID (1) ID27428A (pt)
IL (1) IL140676A0 (pt)
IS (1) IS5805A (pt)
LT (1) LT4850B (pt)
LV (1) LV12665B (pt)
NO (1) NO20010191L (pt)
NZ (1) NZ509211A (pt)
OA (1) OA11581A (pt)
PL (1) PL345598A1 (pt)
PT (1) PT1098897E (pt)
SI (1) SI20638A (pt)
SK (1) SK462001A3 (pt)
TR (1) TR200100122T2 (pt)
WO (1) WO2000004020A1 (pt)
YU (1) YU2901A (pt)
ZA (1) ZA200100320B (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6818643B1 (en) * 1999-12-08 2004-11-16 Bristol-Myers Squibb Company Neurotrophic bicyclic diamides
JP2004532854A (ja) * 2001-05-10 2004-10-28 アグロン ファ−マシュ−テイカルズ インコ−ポレイテッド 複素２環式ｆｋｂｐリガンド
WO2015110271A1 (en) * 2014-01-24 2015-07-30 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Diazabicyclo[4.3.1]decane derivatives for treatment of psychiatric disorders
EP2899192A1 (en) * 2014-01-24 2015-07-29 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Diazabicyclo[4.3.1]decane derivatives for treatment of psychiatric disorders

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4894366A (en) 1984-12-03 1990-01-16 Fujisawa Pharmaceutical Company, Ltd. Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same
US5196352A (en) 1989-01-19 1993-03-23 Merck & Co., Inc. New FK-506 cytosolic binding protein
US5109112A (en) 1989-01-19 1992-04-28 Merck & Co., Inc. FK-506 cytosolic binding protein
US5192773A (en) 1990-07-02 1993-03-09 Vertex Pharmaceuticals, Inc. Immunosuppressive compounds
US5256656A (en) * 1990-07-31 1993-10-26 Nisshin Flour Milling Co., Ltd. Azabicyclo derivatives
US5187166A (en) * 1990-07-31 1993-02-16 Nisshin Flour Milling Co., Ltd. Azabicyclo derivatives and their use as antiemetics
CA2068062A1 (en) 1991-05-07 1992-11-08 Stephen A. Parent Yeast mutants
US5362629A (en) 1991-08-05 1994-11-08 President And Fellows Of Harvard College Detection of immunosuppressants
US5344831A (en) * 1992-01-31 1994-09-06 Nisshin Flour Milling Co., Ltd. Diazabicyclo derivatives
DE4219973A1 (de) 1992-06-19 1993-12-23 Basf Ag N-substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung
US5318895A (en) 1992-10-05 1994-06-07 Merck & Co., Inc. Aspergillus niger mutants
US5798355A (en) 1995-06-07 1998-08-25 Gpi Nil Holdings, Inc. Inhibitors of rotamase enzyme activity
JP3235913B2 (ja) * 1993-07-30 2001-12-04 エーザイ株式会社 アミノ安息香酸誘導体
US5612350A (en) 1993-11-30 1997-03-18 Abbott Laboratories Macrocyclic immunomodulators with novel cyclohexyl ring replacements
DE4341402A1 (de) 1993-12-04 1995-06-08 Basf Ag N-substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung
US5457182A (en) 1994-02-15 1995-10-10 Merck & Co., Inc. FK-506 cytosolic binding protein, FKBP12.6
US5622866A (en) 1994-06-23 1997-04-22 Merck & Co., Inc. Expression cassettes useful in construction of integrative and replicative expression vectors for Streptomyces
US5859031A (en) 1995-06-07 1999-01-12 Gpi Nil Holdings, Inc. Small molecule inhibitors of rotamase enzyme activity
US5696135A (en) 1995-06-07 1997-12-09 Gpi Nil Holdings, Inc. Inhibitors of rotamase enzyme activity effective at stimulating neuronal growth
US5614547A (en) 1995-06-07 1997-03-25 Guilford Pharmaceuticals Inc. Small molecule inhibitors of rotamase enzyme
US6037370A (en) 1995-06-08 2000-03-14 Vertex Pharmaceuticals Incorporated Methods and compositions for stimulating neurite growth
US5801197A (en) 1995-10-31 1998-09-01 Gpi Nil Holdings, Inc. Rotamase enzyme activity inhibitors
US5786378A (en) * 1996-09-25 1998-07-28 Gpi Nil Holdings, Inc. Heterocyclic thioesters
US5801187A (en) 1996-09-25 1998-09-01 Gpi-Nil Holdings, Inc. Heterocyclic esters and amides
US5780484A (en) 1996-11-13 1998-07-14 Vertex Pharmaceuticals Incorporated Methods for stimulating neurite growth with piperidine compounds
US5811434A (en) 1996-11-13 1998-09-22 Vertex Pharmacueticals Incorporated Methods and compositions for stimulating neurite growth
US5840736A (en) 1996-11-13 1998-11-24 Vertex Pharmaceuticals Incorporated Methods and compositions for stimulating neurite growth
PA8442401A1 (es) 1996-12-09 2000-05-24 Guilford Pharm Inc Inhibidores polipropilos de ciclofilina
US5935989A (en) 1996-12-31 1999-08-10 Gpi Nil Holdings Inc. N-linked ureas and carbamates of heterocyclic thioesters
US5874449A (en) 1996-12-31 1999-02-23 Gpi Nil Holdings, Inc. N-linked sulfonamides of heterocyclic thioesters
US5721256A (en) 1997-02-12 1998-02-24 Gpi Nil Holdings, Inc. Method of using neurotrophic sulfonamide compounds
ZA98825B (en) 1997-02-27 1998-10-19 Guilford Pharm Inc Method of using neurotrophic carbamates and ureas
US5846979A (en) 1997-02-28 1998-12-08 Gpi Nil Holdings, Inc. N-oxides of heterocyclic esters, amides, thioesters, and ketones

Also Published As

Publication number Publication date
JP2002520413A (ja) 2002-07-09
ATE268772T1 (de) 2004-06-15
GEP20043368B (en) 2004-04-13
CA2337377A1 (en) 2000-01-27
AU756912B2 (en) 2003-01-23
EA200100149A1 (ru) 2001-08-27
PL345598A1 (en) 2001-12-17
TR200100122T2 (tr) 2001-08-21
EP1098897B1 (en) 2004-06-09
LT2001012A (en) 2001-07-25
YU2901A (sh) 2004-05-12
LV12665A (en) 2001-05-20
NO20010191D0 (no) 2001-01-12
DE69917907T2 (de) 2005-06-30
AU4996399A (en) 2000-02-07
BG105268A (en) 2001-11-30
SI20638A (sl) 2002-02-28
HRP20010118A2 (en) 2002-02-28
ES2226409T3 (es) 2005-03-16
KR20010071920A (ko) 2001-07-31
NZ509211A (en) 2002-10-25
HUP0200637A2 (en) 2002-08-28
WO2000004020A1 (en) 2000-01-27
US6630472B1 (en) 2003-10-07
EE200100032A (et) 2002-06-17
NO20010191L (no) 2001-03-16
OA11581A (en) 2004-07-23
LT4850B (lt) 2001-10-25
EP1098897A1 (en) 2001-05-16
ZA200100320B (en) 2002-07-11
DK1098897T3 (da) 2004-10-18
SK462001A3 (en) 2002-02-05
ID27428A (id) 2001-04-05
CN1318067A (zh) 2001-10-17
BR9912423A (pt) 2001-06-05
IL140676A0 (en) 2002-02-10
LV12665B (lv) 2001-11-20
IS5805A (is) 2001-01-12
DE69917907D1 (de) 2004-07-15
HUP0200637A3 (en) 2003-05-28
AP2001002052A0 (en) 2001-03-31

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