AP2009005053A0 - Novel macrocyclic inhibitors of hepatitis c virus replication - Google Patents

Novel macrocyclic inhibitors of hepatitis c virus replication

Info

Publication number
AP2009005053A0
AP2009005053A0 AP2009005053A AP2009005053A AP2009005053A0 AP 2009005053 A0 AP2009005053 A0 AP 2009005053A0 AP 2009005053 A AP2009005053 A AP 2009005053A AP 2009005053 A AP2009005053 A AP 2009005053A AP 2009005053 A0 AP2009005053 A0 AP 2009005053A0
Authority
AP
ARIPO
Prior art keywords
hepatitis
virus replication
novel macrocyclic
macrocyclic inhibitors
inhibitors
Prior art date
Application number
AP2009005053A
Other languages
English (en)
Inventor
Lawrence M Blatt
Original Assignee
Intermune Inc
Array Biopharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intermune Inc, Array Biopharma Inc filed Critical Intermune Inc
Publication of AP2009005053A0 publication Critical patent/AP2009005053A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AP2009005053A 2007-05-03 2008-05-02 Novel macrocyclic inhibitors of hepatitis c virus replication AP2009005053A0 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US91589607P 2007-05-03 2007-05-03
US95763007P 2007-08-23 2007-08-23
US1564407P 2007-12-20 2007-12-20
PCT/US2008/062552 WO2008137779A2 (en) 2007-05-03 2008-05-02 Novel macrocyclic inhibitors of hepatitis c virus replication

Publications (1)

Publication Number Publication Date
AP2009005053A0 true AP2009005053A0 (en) 2009-12-31

Family

ID=39638815

Family Applications (1)

Application Number Title Priority Date Filing Date
AP2009005053A AP2009005053A0 (en) 2007-05-03 2008-05-02 Novel macrocyclic inhibitors of hepatitis c virus replication

Country Status (22)

Country Link
US (1) US20090155209A1 (OSRAM)
EP (2) EP2160392A2 (OSRAM)
JP (1) JP2010528987A (OSRAM)
KR (1) KR20100024920A (OSRAM)
CN (1) CN101784549A (OSRAM)
AP (1) AP2009005053A0 (OSRAM)
AR (1) AR066448A1 (OSRAM)
AU (1) AU2008247509A1 (OSRAM)
BR (1) BRPI0811020A2 (OSRAM)
CA (1) CA2686138A1 (OSRAM)
CL (1) CL2008001274A1 (OSRAM)
CO (1) CO6251243A2 (OSRAM)
EA (1) EA200971026A1 (OSRAM)
EC (1) ECSP099780A (OSRAM)
IL (1) IL201757A0 (OSRAM)
MA (1) MA31496B1 (OSRAM)
MX (1) MX2009011867A (OSRAM)
NZ (1) NZ581606A (OSRAM)
SG (1) SG174809A1 (OSRAM)
TN (1) TN2009000457A1 (OSRAM)
TW (1) TW200906830A (OSRAM)
WO (1) WO2008137779A2 (OSRAM)

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JP2010528987A (ja) 2010-08-26
MA31496B1 (fr) 2010-07-01
SG174809A1 (en) 2011-10-28
CA2686138A1 (en) 2008-11-13
AU2008247509A1 (en) 2008-11-13
CL2008001274A1 (es) 2008-11-03
CO6251243A2 (es) 2011-02-21
US20090155209A1 (en) 2009-06-18
KR20100024920A (ko) 2010-03-08
WO2008137779A3 (en) 2009-01-08
AR066448A1 (es) 2009-08-19
WO2008137779A2 (en) 2008-11-13
EA200971026A1 (ru) 2011-02-28
NZ581606A (en) 2012-06-29
EP2177523A1 (en) 2010-04-21
IL201757A0 (en) 2010-06-16
MX2009011867A (es) 2010-03-22
EP2160392A2 (en) 2010-03-10
BRPI0811020A2 (pt) 2015-07-21
CN101784549A (zh) 2010-07-21
TW200906830A (en) 2009-02-16
TN2009000457A1 (en) 2011-03-31

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