ZA200800859B - Macrocyclic inhibitors of hepatitis C virus - Google Patents

Macrocyclic inhibitors of hepatitis C virus

Info

Publication number
ZA200800859B
ZA200800859B ZA200800859A ZA200800859A ZA200800859B ZA 200800859 B ZA200800859 B ZA 200800859B ZA 200800859 A ZA200800859 A ZA 200800859A ZA 200800859 A ZA200800859 A ZA 200800859A ZA 200800859 B ZA200800859 B ZA 200800859B
Authority
ZA
South Africa
Prior art keywords
hepatitis
virus
macrocyclic inhibitors
macrocyclic
inhibitors
Prior art date
Application number
ZA200800859A
Inventor
Raboisson Pierre Jean-Marie Bernard
Hu Lili
Lindquist Karin Charlotta
Belfrage Anna Karin Gertrud Linnea
Nilsson Karl Magnus
Rosenquist Aasa Annica Kristina
Wallberg Hans Kristian
Classon Bjoern Olof
De Kock Herman Augustinus
Simmen Kenneth Alan
Lindstroem Mats Stefan
Waehling Horst Juergen
Samuelsson Bengt Bertil
Sahlberg Sven Crister
Kahnberg Pia Cecilia
Original Assignee
Tibotec Pharm Ltd
Medivir Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tibotec Pharm Ltd, Medivir Ab filed Critical Tibotec Pharm Ltd
Publication of ZA200800859B publication Critical patent/ZA200800859B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/86Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88Oxygen atoms
    • C07D239/91Oxygen atoms with aryl or aralkyl radicals attached in position 2 or 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
ZA200800859A 2005-07-29 2008-01-28 Macrocyclic inhibitors of hepatitis C virus ZA200800859B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP05107057 2005-07-29

Publications (1)

Publication Number Publication Date
ZA200800859B true ZA200800859B (en) 2009-06-24

Family

ID=35695633

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200800859A ZA200800859B (en) 2005-07-29 2008-01-28 Macrocyclic inhibitors of hepatitis C virus

Country Status (3)

Country Link
CN (1) CN101233131B (en)
UA (1) UA93377C2 (en)
ZA (1) ZA200800859B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103387509B (en) * 2012-05-11 2016-06-08 重庆博腾制药科技股份有限公司 The preparation method of a kind of HCV protease inhibitor intermediate
CN112358450A (en) * 2020-11-19 2021-02-12 南京艾康生物科技有限公司 Synthesis method of 4- (benzyloxy) -2-methyl-1H-benzo [ d ] imidazole-6-carboxylic acid

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6867185B2 (en) * 2001-12-20 2005-03-15 Bristol-Myers Squibb Company Inhibitors of hepatitis C virus
US20050075279A1 (en) * 2002-10-25 2005-04-07 Boehringer Ingelheim International Gmbh Macrocyclic peptides active against the hepatitis C virus
PE20050431A1 (en) * 2003-09-22 2005-07-19 Boehringer Ingelheim Int MACROCYCLIC PEPTIDES ACTIVE AGAINST HEPATITIS C VIRUS

Also Published As

Publication number Publication date
UA93377C2 (en) 2011-02-10
CN101233131A (en) 2008-07-30
CN101233131B (en) 2011-06-08

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