ECSP099780A - Nuevos inhibidores macrociclicos de la replicacion del virus de hepatitis c - Google Patents
Nuevos inhibidores macrociclicos de la replicacion del virus de hepatitis cInfo
- Publication number
- ECSP099780A ECSP099780A EC2009009780A ECSP099780A ECSP099780A EC SP099780 A ECSP099780 A EC SP099780A EC 2009009780 A EC2009009780 A EC 2009009780A EC SP099780 A ECSP099780 A EC SP099780A EC SP099780 A ECSP099780 A EC SP099780A
- Authority
- EC
- Ecuador
- Prior art keywords
- hepatitis
- macrociclic
- inhibitors
- new
- methods
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Pyrrole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
Compuestos de fórmula general I, y composiciones, incluyendo composiciones farmacéuticas, que comprenden dicho compuesto. Además, en las realizaciones se proporcionan métodos de tratamiento, incluyendo métodos para tratar una infección de virus de hepatitis C y métodos para tratar la fibrosis hepática, donde los métodos generalmente comprenden administrarle a un individuo que lo necesita una cantidad eficaz del compuesto o la composición mencionada.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US91589607P | 2007-05-03 | 2007-05-03 | |
US95763007P | 2007-08-23 | 2007-08-23 | |
US1564407P | 2007-12-20 | 2007-12-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
ECSP099780A true ECSP099780A (es) | 2010-01-29 |
Family
ID=39638815
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EC2009009780A ECSP099780A (es) | 2007-05-03 | 2009-12-02 | Nuevos inhibidores macrociclicos de la replicacion del virus de hepatitis c |
Country Status (22)
Country | Link |
---|---|
US (1) | US20090155209A1 (es) |
EP (2) | EP2177523A1 (es) |
JP (1) | JP2010528987A (es) |
KR (1) | KR20100024920A (es) |
CN (1) | CN101784549A (es) |
AP (1) | AP2009005053A0 (es) |
AR (1) | AR066448A1 (es) |
AU (1) | AU2008247509A1 (es) |
BR (1) | BRPI0811020A2 (es) |
CA (1) | CA2686138A1 (es) |
CL (1) | CL2008001274A1 (es) |
CO (1) | CO6251243A2 (es) |
EA (1) | EA200971026A1 (es) |
EC (1) | ECSP099780A (es) |
IL (1) | IL201757A0 (es) |
MA (1) | MA31496B1 (es) |
MX (1) | MX2009011867A (es) |
NZ (1) | NZ581606A (es) |
SG (1) | SG174809A1 (es) |
TN (1) | TN2009000457A1 (es) |
TW (1) | TW200906830A (es) |
WO (1) | WO2008137779A2 (es) |
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EA200971041A1 (ru) | 2007-05-10 | 2010-08-30 | Интермьюн, Инк. | Новые пептидные ингибиторы репликации вируса гепатита с |
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-
2008
- 2008-05-02 EP EP09177761A patent/EP2177523A1/en not_active Withdrawn
- 2008-05-02 US US12/114,639 patent/US20090155209A1/en not_active Abandoned
- 2008-05-02 JP JP2010507576A patent/JP2010528987A/ja active Pending
- 2008-05-02 CN CN200880018710A patent/CN101784549A/zh active Pending
- 2008-05-02 BR BRPI0811020-4A patent/BRPI0811020A2/pt not_active IP Right Cessation
- 2008-05-02 EA EA200971026A patent/EA200971026A1/ru unknown
- 2008-05-02 WO PCT/US2008/062552 patent/WO2008137779A2/en active Application Filing
- 2008-05-02 KR KR1020097024599A patent/KR20100024920A/ko not_active Application Discontinuation
- 2008-05-02 AP AP2009005053A patent/AP2009005053A0/en unknown
- 2008-05-02 NZ NZ581606A patent/NZ581606A/xx not_active IP Right Cessation
- 2008-05-02 AU AU2008247509A patent/AU2008247509A1/en not_active Abandoned
- 2008-05-02 CL CL2008001274A patent/CL2008001274A1/es unknown
- 2008-05-02 MX MX2009011867A patent/MX2009011867A/es not_active Application Discontinuation
- 2008-05-02 EP EP08755035A patent/EP2160392A2/en not_active Withdrawn
- 2008-05-02 SG SG2011065919A patent/SG174809A1/en unknown
- 2008-05-02 CA CA002686138A patent/CA2686138A1/en not_active Abandoned
- 2008-05-05 TW TW097116495A patent/TW200906830A/zh unknown
- 2008-05-05 AR ARP080101901A patent/AR066448A1/es unknown
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2009
- 2009-10-26 IL IL201757A patent/IL201757A0/en unknown
- 2009-10-30 TN TNP2009000457A patent/TN2009000457A1/fr unknown
- 2009-11-26 MA MA32378A patent/MA31496B1/fr unknown
- 2009-11-30 CO CO09136460A patent/CO6251243A2/es not_active Application Discontinuation
- 2009-12-02 EC EC2009009780A patent/ECSP099780A/es unknown
Also Published As
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TW200906830A (en) | 2009-02-16 |
MX2009011867A (es) | 2010-03-22 |
AR066448A1 (es) | 2009-08-19 |
BRPI0811020A2 (pt) | 2015-07-21 |
CA2686138A1 (en) | 2008-11-13 |
WO2008137779A2 (en) | 2008-11-13 |
CO6251243A2 (es) | 2011-02-21 |
TN2009000457A1 (en) | 2011-03-31 |
CL2008001274A1 (es) | 2008-11-03 |
EP2177523A1 (en) | 2010-04-21 |
AU2008247509A1 (en) | 2008-11-13 |
MA31496B1 (fr) | 2010-07-01 |
AP2009005053A0 (en) | 2009-12-31 |
IL201757A0 (en) | 2010-06-16 |
CN101784549A (zh) | 2010-07-21 |
WO2008137779A3 (en) | 2009-01-08 |
US20090155209A1 (en) | 2009-06-18 |
EA200971026A1 (ru) | 2011-02-28 |
NZ581606A (en) | 2012-06-29 |
SG174809A1 (en) | 2011-10-28 |
KR20100024920A (ko) | 2010-03-08 |
EP2160392A2 (en) | 2010-03-10 |
JP2010528987A (ja) | 2010-08-26 |
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