ZW4294A1 - Heterocyclic derivatives - Google Patents

Heterocyclic derivatives

Info

Publication number
ZW4294A1
ZW4294A1 ZW4294A ZW4294A ZW4294A1 ZW 4294 A1 ZW4294 A1 ZW 4294A1 ZW 4294 A ZW4294 A ZW 4294A ZW 4294 A ZW4294 A ZW 4294A ZW 4294 A1 ZW4294 A1 ZW 4294A1
Authority
ZW
Zimbabwe
Prior art keywords
heterocyclic derivatives
ylüphenoxybutyric
piperazin
fibrinogen
iiia
Prior art date
Application number
ZW4294A
Other languages
English (en)
Inventor
Michael Garth Wayne
Michael James Smithers
John Wall Rayner
Alan Wellington Faull
Robert James Pearce
Andrew George Brewster
Richard Eden Shute
Stuart Dennett Mills
Peter William Rodney Caulkett
Original Assignee
Zeneca Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB939306453A external-priority patent/GB9306453D0/en
Priority claimed from GB939325605A external-priority patent/GB9325605D0/en
Application filed by Zeneca Ltd filed Critical Zeneca Ltd
Publication of ZW4294A1 publication Critical patent/ZW4294A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/74Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
  • Electrochromic Elements, Electrophoresis, Or Variable Reflection Or Absorption Elements (AREA)
  • Electroluminescent Light Sources (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyridine Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Pyrrole Compounds (AREA)
ZW4294A 1993-03-29 1994-03-28 Heterocyclic derivatives ZW4294A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB939306453A GB9306453D0 (en) 1993-03-29 1993-03-29 Heterocyclic derivatives
GB939325605A GB9325605D0 (en) 1993-12-15 1993-12-15 Heterocyclic derivatives

Publications (1)

Publication Number Publication Date
ZW4294A1 true ZW4294A1 (en) 1994-12-21

Family

ID=26302668

Family Applications (1)

Application Number Title Priority Date Filing Date
ZW4294A ZW4294A1 (en) 1993-03-29 1994-03-28 Heterocyclic derivatives

Country Status (26)

Country Link
US (1) US5556977A (es)
EP (2) EP0825184B1 (es)
JP (1) JPH08508291A (es)
KR (1) KR100231089B1 (es)
CN (1) CN1120334A (es)
AT (2) ATE202345T1 (es)
AU (1) AU692438B2 (es)
BR (1) BR9406613A (es)
CA (1) CA2156070A1 (es)
CZ (1) CZ250995A3 (es)
DE (2) DE69427548T2 (es)
DK (2) DK0825184T3 (es)
ES (2) ES2159798T3 (es)
FI (1) FI954616A0 (es)
GB (1) GB9406143D0 (es)
GR (2) GR3027751T3 (es)
HU (2) HUT72088A (es)
IL (1) IL109144A (es)
NO (1) NO305244B1 (es)
NZ (1) NZ262941A (es)
PL (1) PL310889A1 (es)
PT (1) PT825184E (es)
SK (1) SK120895A3 (es)
TW (1) TW276254B (es)
WO (1) WO1994022834A1 (es)
ZW (1) ZW4294A1 (es)

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FR2734818B1 (fr) * 1995-06-01 1998-07-10 Zeneca Ltd Acide (-)-(3r)-3-methyl-4-{4-[4-(4-pyridyl)piperazine-1-yl- phenoxy}-butyrique, procede pour sa preparation et composition pharmaceutique le contenant
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UA56197C2 (uk) * 1996-11-08 2003-05-15 Зенека Лімітед Гетероциклічні похідні
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JP2002516305A (ja) 1998-05-12 2002-06-04 アメリカン・ホーム・プロダクツ・コーポレイション インスリン抵抗性および高血糖症の治療に有用な2,3,5−置換ビフェニル
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US6232322B1 (en) 1998-05-12 2001-05-15 American Home Products Corporation Biphenyl oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia
US6221902B1 (en) 1998-05-12 2001-04-24 American Home Products Corporation Biphenyl sulfonyl aryl carboxylic acids useful in the treatment of insulin resistance and hyperglycemia
US6451827B2 (en) 1998-05-12 2002-09-17 Wyeth 2,3,5-substituted biphenyls useful in the treatment of insulin resistance and hyperglycemia
WO2000006158A1 (en) * 1998-07-31 2000-02-10 Eli Lilly And Company Heterocyclyl sulphonamide derivatives
GB9902989D0 (en) 1999-02-11 1999-03-31 Zeneca Ltd Heterocyclic derivatives
JP2002542224A (ja) * 1999-04-19 2002-12-10 コーエラカント コーポレイション Ii型糖尿病の治療薬としてのppar−(ガンマ)作用物質
US6310081B1 (en) 1999-05-10 2001-10-30 American Home Products Corporation Biphenyl sulfonyl aryl carboxylic acids useful in the treatment of insulin resistance and hyperglycemia
EP1330444B1 (en) 2000-11-01 2011-03-23 Millennium Pharmaceuticals, Inc. Nitrogenous heterocyclic compounds and process for making them
DE202011000090U1 (de) 2011-01-14 2011-04-21 E-LEAD ELECTRONIC CO., LTD., Shengang Shiang Fahrzeug-Audiosystem mit auswechselbarem Plug-In-Computer
JP7065951B2 (ja) 2017-09-22 2022-05-12 ジュビラント エピパッド エルエルシー Pad阻害剤としての複素環式化合物
MX2020003341A (es) 2017-10-18 2020-09-17 Jubilant Epipad LLC Compuestos de imidazo-piridina como inhibidores de pad.
CN111386265A (zh) 2017-11-06 2020-07-07 朱比连特普罗德尔有限责任公司 作为pd1/pd-l1活化的抑制剂的嘧啶衍生物
WO2019102494A1 (en) 2017-11-24 2019-05-31 Jubilant Biosys Limited Heterocyclic compounds as prmt5 inhibitors
MX2020009517A (es) 2018-03-13 2021-01-20 Jubilant Prodel LLC Compuestos biciclicos como inhibidores de la interaccion/activacio n de pdl/pd-l1.

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Also Published As

Publication number Publication date
BR9406613A (pt) 1996-02-06
EP0691959A1 (en) 1996-01-17
NO305244B1 (no) 1999-04-26
CZ250995A3 (en) 1996-01-17
DE69427548T2 (de) 2002-04-18
NO953837D0 (no) 1995-09-28
DK0825184T3 (da) 2001-09-10
PL310889A1 (en) 1996-01-08
ES2159798T3 (es) 2001-10-16
DE69427548D1 (de) 2001-07-26
EP0825184A1 (en) 1998-02-25
IL109144A (en) 2000-02-29
EP0825184B1 (en) 2001-06-20
DK0691959T3 (da) 1999-04-26
CN1120334A (zh) 1996-04-10
HUT72088A (en) 1996-03-28
GB9406143D0 (en) 1994-05-18
NO953837L (no) 1995-09-28
CA2156070A1 (en) 1994-10-13
DE69411900D1 (de) 1998-08-27
ATE168678T1 (de) 1998-08-15
KR100231089B1 (ko) 1999-11-15
AU6288994A (en) 1994-10-24
IL109144A0 (en) 1994-06-24
ES2119184T3 (es) 1998-10-01
DE69411900T2 (de) 1998-12-10
FI954616A (fi) 1995-09-28
US5556977A (en) 1996-09-17
JPH08508291A (ja) 1996-09-03
PT825184E (pt) 2001-11-30
TW276254B (es) 1996-05-21
EP0691959B1 (en) 1998-07-22
GR3036640T3 (en) 2001-12-31
GR3027751T3 (en) 1998-11-30
SK120895A3 (en) 1996-06-05
HU211336A9 (en) 1995-11-28
AU692438B2 (en) 1998-06-11
FI954616A0 (fi) 1995-09-28
NZ262941A (en) 1997-07-27
ATE202345T1 (de) 2001-07-15
WO1994022834A1 (en) 1994-10-13
HU9502290D0 (en) 1995-10-30

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