ATE202345T1 - Heterozyklische derivate als plätchenaggregationsinhibitoren - Google Patents

Heterozyklische derivate als plätchenaggregationsinhibitoren

Info

Publication number
ATE202345T1
ATE202345T1 AT97117909T AT97117909T ATE202345T1 AT E202345 T1 ATE202345 T1 AT E202345T1 AT 97117909 T AT97117909 T AT 97117909T AT 97117909 T AT97117909 T AT 97117909T AT E202345 T1 ATE202345 T1 AT E202345T1
Authority
AT
Austria
Prior art keywords
aggregation inhibitors
heterocyclic derivatives
plate aggregation
plate
ylüphenoxybutyric
Prior art date
Application number
AT97117909T
Other languages
English (en)
Inventor
Stuart Dennett Mills
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB939306453A external-priority patent/GB9306453D0/en
Priority claimed from GB939325605A external-priority patent/GB9325605D0/en
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of ATE202345T1 publication Critical patent/ATE202345T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Electroluminescent Light Sources (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
  • Electrochromic Elements, Electrophoresis, Or Variable Reflection Or Absorption Elements (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyrrole Compounds (AREA)
  • Peptides Or Proteins (AREA)
AT97117909T 1993-03-29 1994-03-28 Heterozyklische derivate als plätchenaggregationsinhibitoren ATE202345T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB939306453A GB9306453D0 (en) 1993-03-29 1993-03-29 Heterocyclic derivatives
GB939325605A GB9325605D0 (en) 1993-12-15 1993-12-15 Heterocyclic derivatives

Publications (1)

Publication Number Publication Date
ATE202345T1 true ATE202345T1 (de) 2001-07-15

Family

ID=26302668

Family Applications (2)

Application Number Title Priority Date Filing Date
AT97117909T ATE202345T1 (de) 1993-03-29 1994-03-28 Heterozyklische derivate als plätchenaggregationsinhibitoren
AT94910494T ATE168678T1 (de) 1993-03-29 1994-03-28 Heterozyklische derivate als plätchenaggregationsinhibitoren

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT94910494T ATE168678T1 (de) 1993-03-29 1994-03-28 Heterozyklische derivate als plätchenaggregationsinhibitoren

Country Status (26)

Country Link
US (1) US5556977A (de)
EP (2) EP0691959B1 (de)
JP (1) JPH08508291A (de)
KR (1) KR100231089B1 (de)
CN (1) CN1120334A (de)
AT (2) ATE202345T1 (de)
AU (1) AU692438B2 (de)
BR (1) BR9406613A (de)
CA (1) CA2156070A1 (de)
CZ (1) CZ250995A3 (de)
DE (2) DE69427548T2 (de)
DK (2) DK0691959T3 (de)
ES (2) ES2119184T3 (de)
FI (1) FI954616A0 (de)
GB (1) GB9406143D0 (de)
GR (2) GR3027751T3 (de)
HU (2) HUT72088A (de)
IL (1) IL109144A (de)
NO (1) NO305244B1 (de)
NZ (1) NZ262941A (de)
PL (1) PL310889A1 (de)
PT (1) PT825184E (de)
SK (1) SK120895A3 (de)
TW (1) TW276254B (de)
WO (1) WO1994022834A1 (de)
ZW (1) ZW4294A1 (de)

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US6110963A (en) * 1998-05-12 2000-08-29 American Home Products Corporation Aryl-oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia
US6232322B1 (en) 1998-05-12 2001-05-15 American Home Products Corporation Biphenyl oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia
DE69917278T2 (de) * 1998-07-31 2005-05-19 Eli Lilly And Co., Indianapolis Heterocyclyl sulphonamid derivate
GB9902989D0 (en) 1999-02-11 1999-03-31 Zeneca Ltd Heterocyclic derivatives
CA2370742A1 (en) * 1999-04-19 2000-10-26 Coelacanth Corporation Ppar-(gamma) agonists as agents for the treatment of type ii diabetes
US6310081B1 (en) 1999-05-10 2001-10-30 American Home Products Corporation Biphenyl sulfonyl aryl carboxylic acids useful in the treatment of insulin resistance and hyperglycemia
DE60144284D1 (de) 2000-11-01 2011-05-05 Millennium Pharm Inc Stickstoffhaltige heterozyklische verbindungen und verfahren zu deren herstellung
DE202011000090U1 (de) 2011-01-14 2011-04-21 E-LEAD ELECTRONIC CO., LTD., Shengang Shiang Fahrzeug-Audiosystem mit auswechselbarem Plug-In-Computer
BR112020005489A2 (pt) 2017-09-22 2020-09-24 Jubilant Epipad Llc, composto da fórmula (i), composto de fórmula (ii), composto de fórmula (iii), processo de preparação de compostos de fórmula (i), processo de preparação de compostos de fórmula (ii), processo de preparação de compostos de fórmula (iii), composição farmacêutica, método para inibir uma ou mais famílias pad em uma célula, método para tratar uma afeção mediada por um ou mais pads, utilização do composto, método para o tratamento e/ou prevenção de uma afeção mediada por um ou mais distúrbios da família pad, método para o tratamento de artrite reumatoide e método de tratamento de câncer
CN111225915B (zh) 2017-10-18 2023-03-07 朱比兰特埃皮帕德有限公司 作为pad抑制剂的咪唑并吡啶化合物
EP3707135A1 (de) 2017-11-06 2020-09-16 Jubilant Prodel LLC Pyrimidinderivate als inhibitoren der pd1/pd-l1-aktivierung
IL274762B2 (en) 2017-11-24 2023-10-01 Jubilant Episcribe Llc Novel heterocyclic compounds as prmt5 inhibitors
EP3765453A1 (de) 2018-03-13 2021-01-20 Jubilant Prodel LLC Bicyclische verbindungen als inhibitoren der pd1/pd-l1-interaktion/aktivierung

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Also Published As

Publication number Publication date
FI954616L (fi) 1995-09-28
DE69411900D1 (de) 1998-08-27
BR9406613A (pt) 1996-02-06
DE69427548T2 (de) 2002-04-18
EP0825184A1 (de) 1998-02-25
EP0691959A1 (de) 1996-01-17
KR100231089B1 (ko) 1999-11-15
ES2119184T3 (es) 1998-10-01
HUT72088A (en) 1996-03-28
GR3027751T3 (en) 1998-11-30
US5556977A (en) 1996-09-17
PT825184E (pt) 2001-11-30
EP0691959B1 (de) 1998-07-22
NO953837D0 (no) 1995-09-28
CZ250995A3 (en) 1996-01-17
ZW4294A1 (en) 1994-12-21
CN1120334A (zh) 1996-04-10
NO953837L (no) 1995-09-28
DK0691959T3 (da) 1999-04-26
FI954616A7 (fi) 1995-09-28
TW276254B (de) 1996-05-21
IL109144A0 (en) 1994-06-24
AU6288994A (en) 1994-10-24
NO305244B1 (no) 1999-04-26
JPH08508291A (ja) 1996-09-03
DE69427548D1 (de) 2001-07-26
CA2156070A1 (en) 1994-10-13
FI954616A0 (fi) 1995-09-28
AU692438B2 (en) 1998-06-11
HU211336A9 (en) 1995-11-28
ATE168678T1 (de) 1998-08-15
IL109144A (en) 2000-02-29
NZ262941A (en) 1997-07-27
DK0825184T3 (da) 2001-09-10
GR3036640T3 (en) 2001-12-31
WO1994022834A1 (en) 1994-10-13
GB9406143D0 (en) 1994-05-18
EP0825184B1 (de) 2001-06-20
HU9502290D0 (en) 1995-10-30
SK120895A3 (en) 1996-06-05
PL310889A1 (en) 1996-01-08
ES2159798T3 (es) 2001-10-16
DE69411900T2 (de) 1998-12-10

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