GR3036640T3 - Heterocyclic derivatives as platelet aggregation inhibitors - Google Patents
Heterocyclic derivatives as platelet aggregation inhibitorsInfo
- Publication number
- GR3036640T3 GR3036640T3 GR20010401498T GR20010401498T GR3036640T3 GR 3036640 T3 GR3036640 T3 GR 3036640T3 GR 20010401498 T GR20010401498 T GR 20010401498T GR 20010401498 T GR20010401498 T GR 20010401498T GR 3036640 T3 GR3036640 T3 GR 3036640T3
- Authority
- GR
- Greece
- Prior art keywords
- platelet aggregation
- aggregation inhibitors
- heterocyclic derivatives
- ylüphenoxybutyric
- piperazin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Hematology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Electroluminescent Light Sources (AREA)
- Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
- Electrochromic Elements, Electrophoresis, Or Variable Reflection Or Absorption Elements (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrrole Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pyridine Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB939306453A GB9306453D0 (en) | 1993-03-29 | 1993-03-29 | Heterocyclic derivatives |
GB939325605A GB9325605D0 (en) | 1993-12-15 | 1993-12-15 | Heterocyclic derivatives |
EP94910494A EP0691959B1 (en) | 1993-03-29 | 1994-03-28 | Heterocyclic derivatives as platelet aggregation inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
GR3036640T3 true GR3036640T3 (en) | 2001-12-31 |
Family
ID=26302668
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GR980401930T GR3027751T3 (en) | 1993-03-29 | 1998-08-27 | Heterocyclic derivatives as platelet aggregation inhibitors |
GR20010401498T GR3036640T3 (en) | 1993-03-29 | 2001-09-18 | Heterocyclic derivatives as platelet aggregation inhibitors |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GR980401930T GR3027751T3 (en) | 1993-03-29 | 1998-08-27 | Heterocyclic derivatives as platelet aggregation inhibitors |
Country Status (26)
Country | Link |
---|---|
US (1) | US5556977A (el) |
EP (2) | EP0691959B1 (el) |
JP (1) | JPH08508291A (el) |
KR (1) | KR100231089B1 (el) |
CN (1) | CN1120334A (el) |
AT (2) | ATE168678T1 (el) |
AU (1) | AU692438B2 (el) |
BR (1) | BR9406613A (el) |
CA (1) | CA2156070A1 (el) |
CZ (1) | CZ250995A3 (el) |
DE (2) | DE69411900T2 (el) |
DK (2) | DK0691959T3 (el) |
ES (2) | ES2119184T3 (el) |
FI (1) | FI954616A0 (el) |
GB (1) | GB9406143D0 (el) |
GR (2) | GR3027751T3 (el) |
HU (2) | HUT72088A (el) |
IL (1) | IL109144A (el) |
NO (1) | NO305244B1 (el) |
NZ (1) | NZ262941A (el) |
PL (1) | PL310889A1 (el) |
PT (1) | PT825184E (el) |
SK (1) | SK120895A3 (el) |
TW (1) | TW276254B (el) |
WO (1) | WO1994022834A1 (el) |
ZW (1) | ZW4294A1 (el) |
Families Citing this family (43)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5750754A (en) * | 1993-03-29 | 1998-05-12 | Zeneca Limited | Heterocyclic compounds |
IL115420A0 (en) | 1994-09-26 | 1995-12-31 | Zeneca Ltd | Aminoheterocyclic derivatives |
US5700801A (en) * | 1994-12-23 | 1997-12-23 | Karl Thomae, Gmbh | Piperazine derivatives, pharmaceutical compositions containing these compounds, their use and processes for preparing them |
EE9700141A (et) * | 1994-12-23 | 1997-12-15 | Dr. Karl Thomae Gmbh | Piperasiinderivaadid, neid sisaldavad ravimid, nende kasutamine ja valmistamise meetod |
GB2304340B (en) * | 1995-06-01 | 1998-07-29 | Zeneca Ltd | (-)-(3r)-3-methyl-4-{4-[4-(4-pyridyl)piperazin-1-yl]phenoxy} butyric acid as cellular adhesion inhibitor |
FR2734818B1 (fr) * | 1995-06-01 | 1998-07-10 | Zeneca Ltd | Acide (-)-(3r)-3-methyl-4-{4-[4-(4-pyridyl)piperazine-1-yl- phenoxy}-butyrique, procede pour sa preparation et composition pharmaceutique le contenant |
DE19524765A1 (de) * | 1995-07-07 | 1997-01-09 | Boehringer Mannheim Gmbh | Neue Oxazolidinonderivate, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel |
AU727569B2 (en) * | 1995-11-17 | 2000-12-14 | Warner-Lambert Company | Sulfonamide inhibitors of matrix metalloproteinases |
GB9525620D0 (en) * | 1995-12-15 | 1996-02-14 | Glaxo Group Ltd | Chemical compounds |
WO1997028128A1 (en) * | 1996-02-02 | 1997-08-07 | Zeneca Limited | Heterocyclic compounds useful as pharmaceutical agents |
GB9602166D0 (en) * | 1996-02-02 | 1996-04-03 | Zeneca Ltd | Aminoheterocyclic derivatives |
US5780480A (en) * | 1996-02-28 | 1998-07-14 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
AU712082B2 (en) * | 1996-02-28 | 1999-10-28 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
AU2044297A (en) * | 1996-03-29 | 1997-10-22 | Meiji Seika Kaisha Ltd. | Novel heterocyclic compounds having platelet aggregation inhibitory effects |
US5990107A (en) * | 1996-06-28 | 1999-11-23 | Merck & Co., Inc. | Fibrinogen receptor antagonist prodrugs |
JP2000514061A (ja) * | 1996-06-28 | 2000-10-24 | メルク エンド カンパニー インコーポレーテッド | フィブリノーゲン受容体拮抗物質 |
US5932582A (en) * | 1996-06-28 | 1999-08-03 | Merck & Co., Inc. | Fibrinogen receptor antagonist prodrugs |
WO1998000144A1 (en) * | 1996-06-28 | 1998-01-08 | Merck & Co., Inc. | Fibrinogen receptor antagonist prodrugs |
US5854245A (en) * | 1996-06-28 | 1998-12-29 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
GB9821483D0 (en) | 1998-10-03 | 1998-11-25 | Glaxo Group Ltd | Chemical compounds |
UA56197C2 (uk) | 1996-11-08 | 2003-05-15 | Зенека Лімітед | Гетероциклічні похідні |
US5945545A (en) * | 1996-12-13 | 1999-08-31 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
WO1998035959A1 (en) | 1997-02-13 | 1998-08-20 | Zeneca Limited | Heterocyclic compounds useful as oxido-squalene cyclase inhibitors |
WO1998035956A1 (en) | 1997-02-13 | 1998-08-20 | Zeneca Limited | Heterocyclic compounds useful as oxido-squalene cyclase inhibitors |
GB9715895D0 (en) | 1997-07-29 | 1997-10-01 | Zeneca Ltd | Heterocyclic compounds |
US6166069A (en) | 1998-05-12 | 2000-12-26 | American Home Products Corporation | Phenyl oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia |
US6232322B1 (en) | 1998-05-12 | 2001-05-15 | American Home Products Corporation | Biphenyl oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia |
US6699896B1 (en) | 1998-05-12 | 2004-03-02 | Wyeth | Oxazole-aryl-carboxylic acids useful in the treatment of insulin resistance and hyperglycemia |
US6451827B2 (en) | 1998-05-12 | 2002-09-17 | Wyeth | 2,3,5-substituted biphenyls useful in the treatment of insulin resistance and hyperglycemia |
AU4072799A (en) | 1998-05-12 | 1999-12-13 | American Home Products Corporation | 2,3,5-substituted biphenyls useful in the treatment of insulin resistance and hyperglycemia |
US6110963A (en) * | 1998-05-12 | 2000-08-29 | American Home Products Corporation | Aryl-oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia |
US6221902B1 (en) | 1998-05-12 | 2001-04-24 | American Home Products Corporation | Biphenyl sulfonyl aryl carboxylic acids useful in the treatment of insulin resistance and hyperglycemia |
JP2002521444A (ja) * | 1998-07-31 | 2002-07-16 | イーライ・リリー・アンド・カンパニー | 複素環スルホンアミド誘導体 |
GB9902989D0 (en) | 1999-02-11 | 1999-03-31 | Zeneca Ltd | Heterocyclic derivatives |
ATE299861T1 (de) * | 1999-04-19 | 2005-08-15 | Coelacanth Corp | Ppar-(gamma) agonisten zur behandlung von type ii diabetes |
US6310081B1 (en) | 1999-05-10 | 2001-10-30 | American Home Products Corporation | Biphenyl sulfonyl aryl carboxylic acids useful in the treatment of insulin resistance and hyperglycemia |
WO2002036587A2 (en) | 2000-11-01 | 2002-05-10 | Cor Therapeutics, Inc. | Process for the production of 4-quinazolinylpiperazin-1-carboxylic acid phenylamides |
DE202011000090U1 (de) | 2011-01-14 | 2011-04-21 | E-LEAD ELECTRONIC CO., LTD., Shengang Shiang | Fahrzeug-Audiosystem mit auswechselbarem Plug-In-Computer |
NZ762985A (en) | 2017-09-22 | 2024-03-22 | Jubilant Epipad LLC | Heterocyclic compounds as pad inhibitors |
HUE061607T2 (hu) | 2017-10-18 | 2023-07-28 | Jubilant Epipad LLC | Imidazopiridin vegyületek mint PAD inhibitorok |
CN111386265A (zh) | 2017-11-06 | 2020-07-07 | 朱比连特普罗德尔有限责任公司 | 作为pd1/pd-l1活化的抑制剂的嘧啶衍生物 |
EP3704120B1 (en) | 2017-11-24 | 2024-03-06 | Jubilant Episcribe LLC | Heterocyclic compounds as prmt5 inhibitors |
BR112020018610A2 (pt) | 2018-03-13 | 2020-12-29 | Jubilant Prodel LLC | Compostos de fórmula i, fórmula ii, fórmula iii, fórmula iv, fórmula v, fórmula vi, ou seus polimorfos, estereoisômeros, tautômeros, profármacos, solvatos e sais farmaceuticamente aceitáveis dos mesmos e uso dos mesmos; processo de preparação; composição farmacêutica; e método para o tratamento e/ou prevenção de várias doenças, que incluem câncer e doenças infecciosas |
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JPH07503459A (ja) * | 1992-01-21 | 1995-04-13 | グラクソ、グループ、リミテッド | 酢酸誘導体 |
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-
1994
- 1994-03-28 DK DK94910494T patent/DK0691959T3/da active
- 1994-03-28 EP EP94910494A patent/EP0691959B1/en not_active Expired - Lifetime
- 1994-03-28 AT AT94910494T patent/ATE168678T1/de not_active IP Right Cessation
- 1994-03-28 DK DK97117909T patent/DK0825184T3/da active
- 1994-03-28 ZW ZW4294A patent/ZW4294A1/xx unknown
- 1994-03-28 US US08/218,171 patent/US5556977A/en not_active Expired - Fee Related
- 1994-03-28 KR KR1019950704314A patent/KR100231089B1/ko not_active IP Right Cessation
- 1994-03-28 NZ NZ262941A patent/NZ262941A/en unknown
- 1994-03-28 TW TW083102802A patent/TW276254B/zh active
- 1994-03-28 CN CN94191664A patent/CN1120334A/zh active Pending
- 1994-03-28 DE DE69411900T patent/DE69411900T2/de not_active Expired - Fee Related
- 1994-03-28 IL IL10914494A patent/IL109144A/xx not_active IP Right Cessation
- 1994-03-28 WO PCT/GB1994/000647 patent/WO1994022834A1/en not_active Application Discontinuation
- 1994-03-28 PL PL94310889A patent/PL310889A1/xx unknown
- 1994-03-28 CZ CZ952509A patent/CZ250995A3/cs unknown
- 1994-03-28 AU AU62889/94A patent/AU692438B2/en not_active Ceased
- 1994-03-28 EP EP97117909A patent/EP0825184B1/en not_active Expired - Lifetime
- 1994-03-28 CA CA002156070A patent/CA2156070A1/en not_active Abandoned
- 1994-03-28 AT AT97117909T patent/ATE202345T1/de not_active IP Right Cessation
- 1994-03-28 PT PT97117909T patent/PT825184E/pt unknown
- 1994-03-28 DE DE69427548T patent/DE69427548T2/de not_active Expired - Fee Related
- 1994-03-28 ES ES94910494T patent/ES2119184T3/es not_active Expired - Lifetime
- 1994-03-28 BR BR9406613A patent/BR9406613A/pt not_active Application Discontinuation
- 1994-03-28 ES ES97117909T patent/ES2159798T3/es not_active Expired - Lifetime
- 1994-03-28 JP JP6521810A patent/JPH08508291A/ja active Pending
- 1994-03-28 HU HU9502290A patent/HUT72088A/hu unknown
- 1994-03-28 SK SK1208-95A patent/SK120895A3/sk unknown
- 1994-03-28 GB GB9406143A patent/GB9406143D0/en active Pending
-
1995
- 1995-06-13 HU HU95P/P00193P patent/HU211336A9/hu unknown
- 1995-09-28 FI FI954616A patent/FI954616A0/fi unknown
- 1995-09-28 NO NO953837A patent/NO305244B1/no not_active IP Right Cessation
-
1998
- 1998-08-27 GR GR980401930T patent/GR3027751T3/el unknown
-
2001
- 2001-09-18 GR GR20010401498T patent/GR3036640T3/el not_active IP Right Cessation
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