ZW12385A1 - &-aryl-4-(4,5-dihydro-3,5-dioxo-1,2,4-triazin-2(3h)-yl)-benzeneacetonitriles - Google Patents

&-aryl-4-(4,5-dihydro-3,5-dioxo-1,2,4-triazin-2(3h)-yl)-benzeneacetonitriles

Info

Publication number
ZW12385A1
ZW12385A1 ZW123/85A ZW12385A ZW12385A1 ZW 12385 A1 ZW12385 A1 ZW 12385A1 ZW 123/85 A ZW123/85 A ZW 123/85A ZW 12385 A ZW12385 A ZW 12385A ZW 12385 A1 ZW12385 A1 ZW 12385A1
Authority
ZW
Zimbabwe
Prior art keywords
triazin
dioxo
dihydro
aryl
benzeneacetonitriles
Prior art date
Application number
ZW123/85A
Other languages
English (en)
Inventor
Boeckx Gustaaf
Raeymaekers Alfons
Sipido Victor
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of ZW12385A1 publication Critical patent/ZW12385A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/06—1,2,4-Triazines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/06—1,2,4-Triazines
    • C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
    • C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D253/075—Two hetero atoms, in positions 3 and 5
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Lubricants (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
ZW123/85A 1984-08-01 1985-07-30 &-aryl-4-(4,5-dihydro-3,5-dioxo-1,2,4-triazin-2(3h)-yl)-benzeneacetonitriles ZW12385A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US63653884A 1984-08-01 1984-08-01

Publications (1)

Publication Number Publication Date
ZW12385A1 true ZW12385A1 (en) 1987-02-25

Family

ID=24552347

Family Applications (1)

Application Number Title Priority Date Filing Date
ZW123/85A ZW12385A1 (en) 1984-08-01 1985-07-30 &-aryl-4-(4,5-dihydro-3,5-dioxo-1,2,4-triazin-2(3h)-yl)-benzeneacetonitriles

Country Status (36)

Country Link
EP (1) EP0170316B1 (es)
JP (2) JPS6143176A (es)
KR (1) KR870000787B1 (es)
CN (1) CN1016687B (es)
AT (1) ATE53206T1 (es)
AU (1) AU579653B2 (es)
BG (1) BG46599A3 (es)
CA (2) CA1244024A (es)
CY (1) CY1656A (es)
CZ (1) CZ277962B6 (es)
DE (1) DE3577984D1 (es)
DK (1) DK166414B1 (es)
DZ (1) DZ814A1 (es)
EG (1) EG17589A (es)
ES (2) ES8609284A1 (es)
FI (1) FI90235C (es)
GR (1) GR851837B (es)
HK (1) HK68092A (es)
HU (1) HU194191B (es)
IE (1) IE58076B1 (es)
IL (1) IL75962A (es)
LT (1) LT2069B (es)
LV (2) LV5027A3 (es)
MA (1) MA20497A1 (es)
NO (1) NO171634C (es)
NZ (1) NZ212770A (es)
PH (1) PH21137A (es)
PL (1) PL147667B1 (es)
PT (1) PT80903B (es)
RO (1) RO92300B (es)
SG (1) SG65992G (es)
SK (1) SK278310B6 (es)
SU (1) SU1443799A3 (es)
ZA (1) ZA855793B (es)
ZM (1) ZM5385A1 (es)
ZW (1) ZW12385A1 (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61501032A (ja) * 1984-06-12 1986-05-22 エフ　エム　シ−　コ−ポレ−シヨン 除草剤２↓−アリ−ル↓−１，２，４↓−トリアジン↓−３，５（２ｈ，４ｈ）↓−ジオン化合物及びその硫黄類似化合物
DE3531919A1 (de) * 1985-09-07 1987-03-19 Hoechst Ag Substituierte 2-phenyl-hexahydro-1,2,4-triazin-3,5-dione, verfahren zu ihrer herstellung, sie enthaltende mittel und ihre verwendung
GB8602342D0 (en) * 1986-01-30 1986-03-05 Janssen Pharmaceutica Nv 5 6-dihydro-2-(substituted phenyl)-1 2 4-triazine-3 5(2h 4h)-diones
DE3826058A1 (de) * 1988-07-30 1990-02-08 Bayer Ag Mittel gegen fischparasiten
EP0364765A3 (de) * 1988-10-08 1991-07-17 Bayer Ag Substituierte 1,3,5-Triazintrione, Verfahren zu ihrer Herstellung und ihre Verwendung gegen parasitäre Protozoen
EP0377903A3 (de) * 1989-01-09 1991-07-17 Bayer Ag Substituierte Hexahydro-1,2,4-triazindione, Verfahren zu ihrer Herstellung, Zwischenprodukte dafür und ihre Verwendung
ES2058463T3 (es) * 1989-01-09 1994-11-01 Bayer Ag Agentes contra protozoos en insectos.
CN1044905A (zh) * 1989-02-16 1990-08-29 赫彻斯特股份公司 鱼和昆虫寄生虫对抗剂
DE4030042A1 (de) * 1990-05-17 1991-11-21 Bayer Ag Verwendung von substituierten 1,2,4-triazindionen
EP0476439A1 (de) * 1990-09-18 1992-03-25 Bayer Ag Substituierte 1,2,4-Triazindione, Verfahren zu ihrer Herstellung, Zwischenprodukte dafür und ihre Verwendung
US5830893A (en) * 1997-04-23 1998-11-03 Mortar & Pestle Veterinary Pharmacy, Inc. Treatment of equine protozoan myeloencephalitis using triazinediones
US6867207B2 (en) 1997-07-10 2005-03-15 Janssen Pharmaceutica N.V. IL-5 inhibiting 6-azauracil derivatives
EE200000016A (et) * 1997-07-10 2000-10-16 Janssen Pharmaceutica N.V. IL-5 inhibeerivad 6-asauratsiili derivaadid, nende valmistamismeetod ja kasutamine, farmatseutiline kompositsioon ja selle valmistamismeetod, retseptori markeerimismeetod ja organi visualiseerimismeetod
EP0987265A1 (en) 1998-09-18 2000-03-22 Janssen Pharmaceutica N.V. Interleukin-5 inhibiting 6-azauracil derivatives
DE69936396T2 (de) 1998-12-18 2008-06-19 Janssen Pharmaceutica N.V. Il-5 hemmende 6-uracilderivate
EE200200057A (et) 1999-08-06 2003-04-15 Janssen Pharmaceutica N.V. Kasvutegurit IL-5 pärssiv asauratsiilderivaat, selle saamine ja kasutamine ravimi valmistamiseks ning seda sisaldav farmatseutiline kompositsioon
CN101265238B (zh) * 2007-12-12 2010-06-16 重庆天极旅业有限公司 一种三嗪环衍生物的合成方法
CN101265216B (zh) * 2007-12-18 2012-06-27 重庆华邦胜凯制药有限公司 4-(取代乙氰基)-苯腙衍生物及其合成方法
CN102911080B (zh) * 2012-09-12 2015-01-21 衢州学院 一种制备2,6-二氯-α-(4-氯苯基)-4-硝基苯乙腈的方法
CN107746390B (zh) * 2017-11-21 2021-03-16 连云港市亚晖医药化工有限公司 抗球虫药地克珠利的制备方法
CN113999139A (zh) * 2021-12-03 2022-02-01 杭州臻峰科技有限公司 制备2，6-二氯-α-（4-氯代苯基） -4-硝基苯乙腈的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3912723A (en) * 1971-03-29 1975-10-14 Pfizer 2-Phenyl-as-triazine-3,5(2H,4H)diones
US3905971A (en) * 1971-03-29 1975-09-16 Pfizer 2-Phenyl-as-triazine-3,5(2H,4H)diones
GB1448696A (en) * 1973-05-29 1976-09-08 Pfizer 2-phqnyl-astriazine-3,4-2h,4h-diones

Also Published As

Publication number Publication date
LT2069B (lt) 1993-06-15
SG65992G (en) 1992-09-04
DE3577984D1 (de) 1990-07-05
CN1016687B (zh) 1992-05-20
RO92300B (ro) 1987-12-02
CZ557685A3 (en) 1993-02-17
ES545744A0 (es) 1986-07-16
SU1443799A3 (ru) 1988-12-07
PL254700A1 (en) 1986-09-23
CZ277962B6 (en) 1993-07-14
KR860001796A (ko) 1986-03-22
LV5772B4 (lv) 1997-06-20
ES8609284A1 (es) 1986-07-16
FI90235B (fi) 1993-09-30
AU4566485A (en) 1986-02-06
NO171634B (no) 1993-01-04
RO92300A (ro) 1987-11-30
EP0170316A2 (en) 1986-02-05
FI852958L (fi) 1986-02-02
NO171634C (no) 1993-04-14
LV5772A4 (lv) 1996-12-20
MA20497A1 (fr) 1986-04-01
DZ814A1 (en) 2004-09-13
JPH0420435B2 (es) 1992-04-02
IE58076B1 (en) 1993-06-30
CA1305479C (en) 1992-07-21
CA1244024A (en) 1988-11-01
IE851911L (en) 1986-02-01
IL75962A (en) 1989-09-28
HUT39433A (en) 1986-09-29
PL147667B1 (en) 1989-07-31
NZ212770A (en) 1988-10-28
CY1656A (en) 1993-05-14
AU579653B2 (en) 1988-12-01
SK557685A3 (en) 1996-09-04
JPS6143176A (ja) 1986-03-01
ES552443A0 (es) 1987-05-01
JPH0625177B2 (ja) 1994-04-06
EP0170316B1 (en) 1990-05-30
DK166414B1 (da) 1993-05-17
JPH0517454A (ja) 1993-01-26
BG46599A3 (en) 1990-01-15
ATE53206T1 (de) 1990-06-15
EG17589A (en) 1991-12-30
SK278310B6 (en) 1996-09-04
DK347585A (da) 1986-02-02
EP0170316A3 (en) 1986-11-05
CN85105673A (zh) 1987-01-14
LV5027A3 (lv) 1993-06-10
ZA855793B (en) 1987-03-25
HU194191B (en) 1988-01-28
ZM5385A1 (en) 1987-03-27
ES8705403A1 (es) 1987-05-01
PH21137A (en) 1987-07-27
KR870000787B1 (ko) 1987-04-18
NO853037L (no) 1986-02-03
DK347585D0 (da) 1985-07-31
IL75962A0 (en) 1985-12-31
FI90235C (fi) 1994-01-10
FI852958A0 (fi) 1985-07-31
PT80903A (en) 1985-09-01
HK68092A (en) 1992-09-18
GR851837B (es) 1985-12-02
PT80903B (pt) 1987-11-11

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