BG46599A3 - Method for preparing of benzene azetonitriles - Google Patents
Method for preparing of benzene azetonitrilesInfo
- Publication number
- BG46599A3 BG46599A3 BG071295A BG7129585A BG46599A3 BG 46599 A3 BG46599 A3 BG 46599A3 BG 071295 A BG071295 A BG 071295A BG 7129585 A BG7129585 A BG 7129585A BG 46599 A3 BG46599 A3 BG 46599A3
- Authority
- BG
- Bulgaria
- Prior art keywords
- protozoa
- azetonitriles
- benzene
- preparing
- warm
- Prior art date
Links
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 title 3
- 241001465754 Metazoa Species 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
- C07D253/06—1,2,4-Triazines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
- C07D253/06—1,2,4-Triazines
- C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
- C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D253/075—Two hetero atoms, in positions 3 and 5
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Tropical Medicine & Parasitology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Saccharide Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Lubricants (AREA)
Abstract
Методът намира приложение във фармацевтичната химия за получаване на лекарство за борба с протозоите при топлокръвните животни. Бензолацетонитрилите, по-специално алфа-арил-4-(4,5-дихидро3,5-диоксо-1,2,4-триазин 2(3 н)-ил)-бензолацетонитрилите, са високоефективн при унищожаването или предотвратяването растежа на протозоите в страдащите от протозои топлокръвни животни. 1 претенцияThe method is used in pharmaceutical chemistry to obtain a drug to combat protozoa in warm-blooded animals. Benzoacetonitrile, particularly alpha-aryl-4-(4,5-dihydro3,5-dioxo-1,2,4-triazine 2(3 n )-yl)-benzeneacetonitrile, is highly effective in killing or preventing the growth of protozoa in warm-blooded animals suffering from protozoa. 1 claim
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US63653884A | 1984-08-01 | 1984-08-01 |
Publications (1)
Publication Number | Publication Date |
---|---|
BG46599A3 true BG46599A3 (en) | 1990-01-15 |
Family
ID=24552347
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BG071295A BG46599A3 (en) | 1984-08-01 | 1985-07-30 | Method for preparing of benzene azetonitriles |
Country Status (36)
Country | Link |
---|---|
EP (1) | EP0170316B1 (en) |
JP (2) | JPS6143176A (en) |
KR (1) | KR870000787B1 (en) |
CN (1) | CN1016687B (en) |
AT (1) | ATE53206T1 (en) |
AU (1) | AU579653B2 (en) |
BG (1) | BG46599A3 (en) |
CA (2) | CA1244024A (en) |
CY (1) | CY1656A (en) |
CZ (1) | CZ277962B6 (en) |
DE (1) | DE3577984D1 (en) |
DK (1) | DK166414B1 (en) |
DZ (1) | DZ814A1 (en) |
EG (1) | EG17589A (en) |
ES (2) | ES8609284A1 (en) |
FI (1) | FI90235C (en) |
GR (1) | GR851837B (en) |
HK (1) | HK68092A (en) |
HU (1) | HU194191B (en) |
IE (1) | IE58076B1 (en) |
IL (1) | IL75962A (en) |
LT (1) | LT2069B (en) |
LV (2) | LV5027A3 (en) |
MA (1) | MA20497A1 (en) |
NO (1) | NO171634C (en) |
NZ (1) | NZ212770A (en) |
PH (1) | PH21137A (en) |
PL (1) | PL147667B1 (en) |
PT (1) | PT80903B (en) |
RO (1) | RO92300B (en) |
SG (1) | SG65992G (en) |
SK (1) | SK278310B6 (en) |
SU (1) | SU1443799A3 (en) |
ZA (1) | ZA855793B (en) |
ZM (1) | ZM5385A1 (en) |
ZW (1) | ZW12385A1 (en) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0185731A4 (en) * | 1984-06-12 | 1988-11-02 | Fmc Corp | Herbicidal 2-aryl-1,2,4-triazine-3,5(2h,4h)-diones and sulfur analogs thereof. |
DE3531919A1 (en) * | 1985-09-07 | 1987-03-19 | Hoechst Ag | SUBSTITUTED 2-PHENYL-HEXAHYDRO-1,2,4-TRIAZINE-3,5-DIONE, METHOD FOR THE PRODUCTION THEREOF, MEANS CONTAINING IT AND THEIR USE |
GB8602342D0 (en) * | 1986-01-30 | 1986-03-05 | Janssen Pharmaceutica Nv | 5 6-dihydro-2-(substituted phenyl)-1 2 4-triazine-3 5(2h 4h)-diones |
DE3826058A1 (en) * | 1988-07-30 | 1990-02-08 | Bayer Ag | AGAINST FISH PARASITES |
EP0364765A3 (en) * | 1988-10-08 | 1991-07-17 | Bayer Ag | Substituted 1,3,5-triazinetriones, process for their preparation, and their use against parasitical protozoa |
EP0377903A3 (en) * | 1989-01-09 | 1991-07-17 | Bayer Ag | Substituted hexahydro-1,2,4-triazine diones, processes for their preparation, intermediates and their use |
EP0377904B1 (en) * | 1989-01-09 | 1993-08-18 | Bayer Ag | Agent against protozoae in insects |
CN1044905A (en) * | 1989-02-16 | 1990-08-29 | 赫彻斯特股份公司 | Fish and entomophagous parasite worm antagonist |
DE4030042A1 (en) * | 1990-05-17 | 1991-11-21 | Bayer Ag | USE OF SUBSTITUTED 1,2,4-TRIAZINDIONES |
EP0476439A1 (en) * | 1990-09-18 | 1992-03-25 | Bayer Ag | Substituted 1,2,4-triazindiones, method for their preparation, intermdiates for it and their use |
US5830893A (en) * | 1997-04-23 | 1998-11-03 | Mortar & Pestle Veterinary Pharmacy, Inc. | Treatment of equine protozoan myeloencephalitis using triazinediones |
EE200000016A (en) * | 1997-07-10 | 2000-10-16 | Janssen Pharmaceutica N.V. | IL-5 Inhibiting 6-Azauracil Derivatives, Method and Preparation thereof, Pharmaceutical Composition and Method for its Preparation, Receptor Marking Method and Organ Visualization Method |
US6867207B2 (en) | 1997-07-10 | 2005-03-15 | Janssen Pharmaceutica N.V. | IL-5 inhibiting 6-azauracil derivatives |
EP0987265A1 (en) | 1998-09-18 | 2000-03-22 | Janssen Pharmaceutica N.V. | Interleukin-5 inhibiting 6-azauracil derivatives |
ID28880A (en) | 1998-12-18 | 2001-07-12 | Janssen Pharmaceutica Nv | IL-5 OBSERVATION SOFTWARE |
CA2380759A1 (en) | 1999-08-06 | 2001-02-15 | Janssen Pharmaceutica N.V. | Interleukin-5 inhibiting 6-azauracil derivatives |
CN101265238B (en) * | 2007-12-12 | 2010-06-16 | 重庆天极旅业有限公司 | Method for synthesizing triazine ring derivatives |
CN101265216B (en) * | 2007-12-18 | 2012-06-27 | 重庆华邦胜凯制药有限公司 | 4-(substituted cyano)-phenylhydrazone derivatives and synthesis method thereof |
CN102911080B (en) * | 2012-09-12 | 2015-01-21 | 衢州学院 | Method for preparing 2,6-dichloro-alpha-(4-chlorphenyl)-4-nitro phenylacetonitrile |
CN107746390B (en) * | 2017-11-21 | 2021-03-16 | 连云港市亚晖医药化工有限公司 | Preparation method of anticoccidial drug diclazuril |
CN113999139A (en) * | 2021-12-03 | 2022-02-01 | 杭州臻峰科技有限公司 | Method for preparing 2, 6-dichloro-alpha- (4-chlorophenyl) -4-nitrophenylacetonitrile |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3912723A (en) * | 1971-03-29 | 1975-10-14 | Pfizer | 2-Phenyl-as-triazine-3,5(2H,4H)diones |
US3905971A (en) * | 1971-03-29 | 1975-09-16 | Pfizer | 2-Phenyl-as-triazine-3,5(2H,4H)diones |
GB1448696A (en) * | 1973-05-29 | 1976-09-08 | Pfizer | 2-phqnyl-astriazine-3,4-2h,4h-diones |
-
1985
- 1985-06-28 CA CA000485876A patent/CA1244024A/en not_active Expired
- 1985-07-04 DE DE8585201081T patent/DE3577984D1/en not_active Expired - Lifetime
- 1985-07-04 AT AT85201081T patent/ATE53206T1/en not_active IP Right Cessation
- 1985-07-04 EP EP85201081A patent/EP0170316B1/en not_active Expired - Lifetime
- 1985-07-09 KR KR1019850004883A patent/KR870000787B1/en not_active IP Right Cessation
- 1985-07-11 CN CN85105673A patent/CN1016687B/en not_active Expired
- 1985-07-17 NZ NZ212770A patent/NZ212770A/en unknown
- 1985-07-24 GR GR851837A patent/GR851837B/el unknown
- 1985-07-25 EG EG440/85A patent/EG17589A/en active
- 1985-07-26 PL PL1985254700A patent/PL147667B1/en unknown
- 1985-07-29 DZ DZ850167A patent/DZ814A1/en active
- 1985-07-30 CZ CS855576A patent/CZ277962B6/en not_active IP Right Cessation
- 1985-07-30 SK SK5576-85A patent/SK278310B6/en unknown
- 1985-07-30 BG BG071295A patent/BG46599A3/en unknown
- 1985-07-30 ES ES545744A patent/ES8609284A1/en not_active Expired
- 1985-07-30 IL IL75962A patent/IL75962A/en not_active IP Right Cessation
- 1985-07-30 RO RO119723A patent/RO92300B/en unknown
- 1985-07-30 ZW ZW123/85A patent/ZW12385A1/en unknown
- 1985-07-31 PH PH32584A patent/PH21137A/en unknown
- 1985-07-31 ZM ZM53/85A patent/ZM5385A1/en unknown
- 1985-07-31 SU SU853929257A patent/SU1443799A3/en active
- 1985-07-31 AU AU45664/85A patent/AU579653B2/en not_active Expired
- 1985-07-31 ZA ZA855793A patent/ZA855793B/en unknown
- 1985-07-31 FI FI852958A patent/FI90235C/en not_active IP Right Cessation
- 1985-07-31 HU HU852946A patent/HU194191B/en unknown
- 1985-07-31 MA MA20723A patent/MA20497A1/en unknown
- 1985-07-31 JP JP60167834A patent/JPS6143176A/en active Granted
- 1985-07-31 IE IE191185A patent/IE58076B1/en not_active IP Right Cessation
- 1985-07-31 NO NO853037A patent/NO171634C/en not_active IP Right Cessation
- 1985-07-31 DK DK347585A patent/DK166414B1/en not_active IP Right Cessation
- 1985-08-01 PT PT80903A patent/PT80903B/en unknown
-
1986
- 1986-02-26 ES ES552443A patent/ES8705403A1/en not_active Expired
-
1988
- 1988-06-08 CA CA000568996A patent/CA1305479C/en not_active Expired - Lifetime
-
1991
- 1991-10-09 JP JP3289384A patent/JPH0625177B2/en not_active Expired - Lifetime
-
1992
- 1992-06-30 SG SG659/92A patent/SG65992G/en unknown
- 1992-09-10 HK HK680/92A patent/HK68092A/en not_active IP Right Cessation
- 1992-11-27 LV LV920224A patent/LV5027A3/en unknown
-
1993
- 1993-02-26 LT LTRP370A patent/LT2069B/en unknown
- 1993-05-14 CY CY1656A patent/CY1656A/en unknown
-
1996
- 1996-06-18 LV LV960186A patent/LV5772B4/en unknown
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