LV5027A3 - Alpha-aril-4-(4,5-dihidro-3,5-diokso-1,2,4-triazin-2-(3H)-il)-benzolacetonitrilu iegusanas metode - Google Patents

Alpha-aril-4-(4,5-dihidro-3,5-diokso-1,2,4-triazin-2-(3H)-il)-benzolacetonitrilu iegusanas metode

Info

Publication number
LV5027A3
LV5027A3 LV920224A LV920224A LV5027A3 LV 5027 A3 LV5027 A3 LV 5027A3 LV 920224 A LV920224 A LV 920224A LV 920224 A LV920224 A LV 920224A LV 5027 A3 LV5027 A3 LV 5027A3
Authority
LV
Latvia
Prior art keywords
triazin
dioxo
dihydro
aryl
acetonitrile
Prior art date
Application number
LV920224A
Other languages
English (en)
Latvian (lv)
Inventor
Gustaaf M Boeckx
Alfons H M Raeymaekers
Victor Sipido
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of LV5027A3 publication Critical patent/LV5027A3/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/06—1,2,4-Triazines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/06—1,2,4-Triazines
    • C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
    • C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D253/075—Two hetero atoms, in positions 3 and 5
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Lubricants (AREA)
LV920224A 1984-08-01 1992-11-27 Alpha-aril-4-(4,5-dihidro-3,5-diokso-1,2,4-triazin-2-(3H)-il)-benzolacetonitrilu iegusanas metode LV5027A3 (lv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63653884A 1984-08-01 1984-08-01
SU853929257A SU1443799A3 (ru) 1984-08-01 1985-07-31 Способ получени @ -арил-4- @ 4,5-дигидро-3,5-диоксо-1,2,4-триазин-2-(3Н)-ил @ -бензолацетонитрилов

Publications (1)

Publication Number Publication Date
LV5027A3 true LV5027A3 (lv) 1993-06-10

Family

ID=24552347

Family Applications (2)

Application Number Title Priority Date Filing Date
LV920224A LV5027A3 (lv) 1984-08-01 1992-11-27 Alpha-aril-4-(4,5-dihidro-3,5-diokso-1,2,4-triazin-2-(3H)-il)-benzolacetonitrilu iegusanas metode
LV960186A LV5772B4 (lv) 1984-08-01 1996-06-18 Alfa-Aril-4-(4,5-dihidro-3,5-diokso-1,2,4-triazin-2(3h)-il)benzenacetonitrili

Family Applications After (1)

Application Number Title Priority Date Filing Date
LV960186A LV5772B4 (lv) 1984-08-01 1996-06-18 Alfa-Aril-4-(4,5-dihidro-3,5-diokso-1,2,4-triazin-2(3h)-il)benzenacetonitrili

Country Status (36)

Country Link
EP (1) EP0170316B1 (xx)
JP (2) JPS6143176A (xx)
KR (1) KR870000787B1 (xx)
CN (1) CN1016687B (xx)
AT (1) ATE53206T1 (xx)
AU (1) AU579653B2 (xx)
BG (1) BG46599A3 (xx)
CA (2) CA1244024A (xx)
CY (1) CY1656A (xx)
CZ (1) CZ277962B6 (xx)
DE (1) DE3577984D1 (xx)
DK (1) DK166414B1 (xx)
DZ (1) DZ814A1 (xx)
EG (1) EG17589A (xx)
ES (2) ES8609284A1 (xx)
FI (1) FI90235C (xx)
GR (1) GR851837B (xx)
HK (1) HK68092A (xx)
HU (1) HU194191B (xx)
IE (1) IE58076B1 (xx)
IL (1) IL75962A (xx)
LT (1) LT2069B (xx)
LV (2) LV5027A3 (xx)
MA (1) MA20497A1 (xx)
NO (1) NO171634C (xx)
NZ (1) NZ212770A (xx)
PH (1) PH21137A (xx)
PL (1) PL147667B1 (xx)
PT (1) PT80903B (xx)
RO (1) RO92300B (xx)
SG (1) SG65992G (xx)
SK (1) SK557685A3 (xx)
SU (1) SU1443799A3 (xx)
ZA (1) ZA855793B (xx)
ZM (1) ZM5385A1 (xx)
ZW (1) ZW12385A1 (xx)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU196892B (en) * 1984-06-12 1989-02-28 Fmc Corp Herbicides containing as active substance derivatives of 2-phenil-1,2,4-triasine-3,5-dion and process for production of these derivatives
DE3531919A1 (de) * 1985-09-07 1987-03-19 Hoechst Ag Substituierte 2-phenyl-hexahydro-1,2,4-triazin-3,5-dione, verfahren zu ihrer herstellung, sie enthaltende mittel und ihre verwendung
GB8602342D0 (en) * 1986-01-30 1986-03-05 Janssen Pharmaceutica Nv 5 6-dihydro-2-(substituted phenyl)-1 2 4-triazine-3 5(2h 4h)-diones
DE3826058A1 (de) * 1988-07-30 1990-02-08 Bayer Ag Mittel gegen fischparasiten
EP0364765A3 (de) * 1988-10-08 1991-07-17 Bayer Ag Substituierte 1,3,5-Triazintrione, Verfahren zu ihrer Herstellung und ihre Verwendung gegen parasitäre Protozoen
US5070091A (en) * 1989-01-09 1991-12-03 Bayer Aktiengesellschaft Substituted 1,2,4-triazinediones useful against protozoa in insects
EP0377903A3 (de) * 1989-01-09 1991-07-17 Bayer Ag Substituierte Hexahydro-1,2,4-triazindione, Verfahren zu ihrer Herstellung, Zwischenprodukte dafür und ihre Verwendung
CN1044905A (zh) * 1989-02-16 1990-08-29 赫彻斯特股份公司 鱼和昆虫寄生虫对抗剂
DE4030042A1 (de) * 1990-05-17 1991-11-21 Bayer Ag Verwendung von substituierten 1,2,4-triazindionen
EP0476439A1 (de) * 1990-09-18 1992-03-25 Bayer Ag Substituierte 1,2,4-Triazindione, Verfahren zu ihrer Herstellung, Zwischenprodukte dafür und ihre Verwendung
US5830893A (en) * 1997-04-23 1998-11-03 Mortar & Pestle Veterinary Pharmacy, Inc. Treatment of equine protozoan myeloencephalitis using triazinediones
ID24390A (id) * 1997-07-10 2000-07-13 Janssen Pharmaceutica Nv Turunan-turunan 6-azaurasil penghambat il-5
US6867207B2 (en) 1997-07-10 2005-03-15 Janssen Pharmaceutica N.V. IL-5 inhibiting 6-azauracil derivatives
EP0987265A1 (en) 1998-09-18 2000-03-22 Janssen Pharmaceutica N.V. Interleukin-5 inhibiting 6-azauracil derivatives
UA73107C2 (en) 1998-12-18 2005-06-15 Janssen Pharmaceutica Nv Derivatives of 6-azaurcyle inhibiting il-5
SK1642002A3 (en) 1999-08-06 2003-03-04 Janssen Pharmaceutica Nv Interleukin-5 inhibiting 6-azauracil derivatives
CN101265238B (zh) * 2007-12-12 2010-06-16 重庆天极旅业有限公司 一种三嗪环衍生物的合成方法
CN101265216B (zh) * 2007-12-18 2012-06-27 重庆华邦胜凯制药有限公司 4-(取代乙氰基)-苯腙衍生物及其合成方法
CN102911080B (zh) * 2012-09-12 2015-01-21 衢州学院 一种制备2,6-二氯-α-(4-氯苯基)-4-硝基苯乙腈的方法
CN107746390B (zh) * 2017-11-21 2021-03-16 连云港市亚晖医药化工有限公司 抗球虫药地克珠利的制备方法
CN113999139A (zh) * 2021-12-03 2022-02-01 杭州臻峰科技有限公司 制备2，6-二氯-α-（4-氯代苯基） -4-硝基苯乙腈的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3905971A (en) * 1971-03-29 1975-09-16 Pfizer 2-Phenyl-as-triazine-3,5(2H,4H)diones
US3912723A (en) * 1971-03-29 1975-10-14 Pfizer 2-Phenyl-as-triazine-3,5(2H,4H)diones
GB1448696A (en) * 1973-05-29 1976-09-08 Pfizer 2-phqnyl-astriazine-3,4-2h,4h-diones

Also Published As

Publication number Publication date
LT2069B (lt) 1993-06-15
BG46599A3 (en) 1990-01-15
ES8705403A1 (es) 1987-05-01
ES552443A0 (es) 1987-05-01
IL75962A (en) 1989-09-28
LV5772B4 (lv) 1997-06-20
KR870000787B1 (ko) 1987-04-18
KR860001796A (ko) 1986-03-22
RO92300B (ro) 1987-12-02
DK166414B1 (da) 1993-05-17
CN1016687B (zh) 1992-05-20
CZ277962B6 (en) 1993-07-14
DZ814A1 (en) 2004-09-13
HU194191B (en) 1988-01-28
IE851911L (en) 1986-02-01
FI90235B (fi) 1993-09-30
JPS6143176A (ja) 1986-03-01
ES8609284A1 (es) 1986-07-16
JPH0625177B2 (ja) 1994-04-06
RO92300A (ro) 1987-11-30
JPH0420435B2 (xx) 1992-04-02
ZW12385A1 (en) 1987-02-25
CN85105673A (zh) 1987-01-14
PL254700A1 (en) 1986-09-23
JPH0517454A (ja) 1993-01-26
ATE53206T1 (de) 1990-06-15
EP0170316B1 (en) 1990-05-30
DE3577984D1 (de) 1990-07-05
IL75962A0 (en) 1985-12-31
MA20497A1 (fr) 1986-04-01
NZ212770A (en) 1988-10-28
AU579653B2 (en) 1988-12-01
IE58076B1 (en) 1993-06-30
SK278310B6 (en) 1996-09-04
DK347585A (da) 1986-02-02
ZA855793B (en) 1987-03-25
SU1443799A3 (ru) 1988-12-07
EP0170316A3 (en) 1986-11-05
LV5772A4 (lv) 1996-12-20
ES545744A0 (es) 1986-07-16
PL147667B1 (en) 1989-07-31
ZM5385A1 (en) 1987-03-27
PH21137A (en) 1987-07-27
NO171634B (no) 1993-01-04
DK347585D0 (da) 1985-07-31
FI852958L (fi) 1986-02-02
CA1244024A (en) 1988-11-01
HUT39433A (en) 1986-09-29
PT80903B (pt) 1987-11-11
AU4566485A (en) 1986-02-06
NO171634C (no) 1993-04-14
FI90235C (fi) 1994-01-10
NO853037L (no) 1986-02-03
GR851837B (xx) 1985-12-02
EG17589A (en) 1991-12-30
HK68092A (en) 1992-09-18
PT80903A (en) 1985-09-01
CY1656A (en) 1993-05-14
SG65992G (en) 1992-09-04
CZ557685A3 (en) 1993-02-17
EP0170316A2 (en) 1986-02-05
SK557685A3 (en) 1996-09-04
CA1305479C (en) 1992-07-21
FI852958A0 (fi) 1985-07-31

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