IT1218692B - Procedimento microbiologico per la preparazione di 9 alfa-idrossi-4-androstene-3,17 dione - Google Patents
Procedimento microbiologico per la preparazione di 9 alfa-idrossi-4-androstene-3,17 dioneInfo
- Publication number
- IT1218692B IT1218692B IT67940/87A IT6794087A IT1218692B IT 1218692 B IT1218692 B IT 1218692B IT 67940/87 A IT67940/87 A IT 67940/87A IT 6794087 A IT6794087 A IT 6794087A IT 1218692 B IT1218692 B IT 1218692B
- Authority
- IT
- Italy
- Prior art keywords
- androstene
- dione
- alpha
- hydroxy
- preparation
- Prior art date
Links
- OSVMTWJCGUFAOD-KZQROQTASA-N formestane Chemical compound O=C1CC[C@]2(C)[C@H]3CC[C@](C)(C(CC4)=O)[C@@H]4[C@@H]3CCC2=C1O OSVMTWJCGUFAOD-KZQROQTASA-N 0.000 title 1
- 230000002906 microbiologic effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P33/00—Preparation of steroids
- C12P33/005—Degradation of the lateral chains at position 17
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/863—Mycobacterium
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU864757A HU196627B (en) | 1986-11-18 | 1986-11-18 | Microbiological process for producing y alpha-hydroxy-4-androstene-3,17-dione |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT8767940A0 IT8767940A0 (it) | 1987-11-04 |
| IT1218692B true IT1218692B (it) | 1990-04-19 |
Family
ID=10968841
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT67940/87A IT1218692B (it) | 1986-11-18 | 1987-11-04 | Procedimento microbiologico per la preparazione di 9 alfa-idrossi-4-androstene-3,17 dione |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5004695A (it) |
| JP (1) | JPS6485099A (it) |
| AT (1) | AT396480B (it) |
| DE (1) | DE3739017C2 (it) |
| GB (1) | GB2197869B (it) |
| HU (1) | HU196627B (it) |
| IT (1) | IT1218692B (it) |
| NL (1) | NL8702758A (it) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2052693T3 (es) * | 1987-12-23 | 1994-07-16 | Roussel Uclaf | Preparacion microbiologica de 9-alfa-hidroxi-17-ceto-esteroides. |
| US5298398A (en) * | 1987-12-23 | 1994-03-29 | Gist-Brocades Nv | Preparation of 9-α-hydroxy-17-keto steroids using Mycobacterium species CBS 482.86 |
| US5215894A (en) * | 1992-02-25 | 1993-06-01 | Merck & Co., Inc. | Biological process for producing 17β-N-monosubstituted carbamoyl-11-oxo-4-aza-5-α-androst-3-one testosterone-5-α reductase inhibitors |
| RU2126837C1 (ru) * | 1997-07-18 | 1999-02-27 | Андрюшина Валентина Александровна | Штамм бактерий mycobacterium smegmatis, используемый для окисления стеринов растительного и животного происхождения до андрост-4-ен-3,17-диона |
| CN1224716C (zh) * | 1999-10-22 | 2005-10-26 | 阿克佐诺贝尔公司 | 类固醇的微生物9α-羟基化 |
| KR100418657B1 (ko) * | 2001-10-16 | 2004-02-11 | 주식회사 엘지생명과학 | 마이코박테리움 에스피를 사용하는9-알파-하이드록시-안드로스트-4-엔-3,17-디온의 제조방법 |
| CN112110970A (zh) * | 2020-09-16 | 2020-12-22 | 湖南新合新生物医药有限公司 | 9-oh-ad副产物的回收利用方法及9-oh-ad的制备方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4035236A (en) * | 1975-10-24 | 1977-07-12 | The Upjohn Company | Process for preparing 9α-hydroxyandrostenedione |
| US4221868A (en) * | 1977-10-21 | 1980-09-09 | The Upjohn Company | Process for preparing 9α-OH testosterone |
| JPS5585397A (en) * | 1978-12-21 | 1980-06-27 | Mitsubishi Chem Ind Ltd | Microbiological preparation of 9alpha-hydroxyandrostenedione |
| JPS55138395A (en) * | 1979-04-13 | 1980-10-29 | Mitsubishi Chem Ind Ltd | Production of 9alpha-hydroxyandrosterone compound by microorganism |
| JPS578794A (en) * | 1980-06-17 | 1982-01-18 | Mitsubishi Chem Ind Ltd | Preparation of androstane-type steroid |
| DD232167A3 (de) * | 1982-09-10 | 1986-01-22 | Adw Ddr | Verfahren zur herstellung von androstanderivaten |
| DD248145B3 (de) * | 1984-08-20 | 1991-01-17 | Adw Ddr | Verfahren zur mikrobiellen herstellung von sterolabbauprodukten |
| DD249284B1 (de) * | 1986-05-23 | 1988-08-31 | Adw Ddr | Verfahren zur herstellung von 9alpha-hydroxy-androst-4-en-3,17-dion |
-
1986
- 1986-11-18 HU HU864757A patent/HU196627B/hu not_active IP Right Cessation
-
1987
- 1987-11-04 IT IT67940/87A patent/IT1218692B/it active
- 1987-11-05 US US07/116,872 patent/US5004695A/en not_active Expired - Fee Related
- 1987-11-17 DE DE3739017A patent/DE3739017C2/de not_active Expired - Fee Related
- 1987-11-18 NL NL8702758A patent/NL8702758A/nl not_active Application Discontinuation
- 1987-11-18 AT AT0304487A patent/AT396480B/de active
- 1987-11-18 JP JP62291665A patent/JPS6485099A/ja active Pending
- 1987-11-18 GB GB8726949A patent/GB2197869B/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| GB2197869A (en) | 1988-06-02 |
| NL8702758A (nl) | 1988-06-16 |
| DE3739017A1 (de) | 1988-06-01 |
| US5004695A (en) | 1991-04-02 |
| HU196627B (en) | 1988-12-28 |
| GB2197869B (en) | 1990-07-25 |
| IT8767940A0 (it) | 1987-11-04 |
| AT396480B (de) | 1993-09-27 |
| GB8726949D0 (en) | 1987-12-23 |
| ATA304487A (de) | 1993-01-15 |
| HUT46077A (en) | 1988-09-28 |
| DE3739017C2 (de) | 1996-06-20 |
| JPS6485099A (en) | 1989-03-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19951121 |