ZA986904B - Process - Google Patents

Process

Info

Publication number
ZA986904B
ZA986904B ZA986904A ZA986904A ZA986904B ZA 986904 B ZA986904 B ZA 986904B ZA 986904 A ZA986904 A ZA 986904A ZA 986904 A ZA986904 A ZA 986904A ZA 986904 B ZA986904 B ZA 986904B
Authority
ZA
South Africa
Prior art keywords
füä1
ethylü
dibenzoäb
hydroxyethoxy
piperazinyl
Prior art date
Application number
ZA986904A
Other languages
English (en)
Inventor
Evan William Snape
Original Assignee
Zeneca Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zeneca Ltd filed Critical Zeneca Ltd
Publication of ZA986904B publication Critical patent/ZA986904B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D281/00Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02Seven-membered rings
    • C07D281/04Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/12Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D281/16[b, f]-condensed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Glass Compositions (AREA)
  • Iron Core Of Rotating Electric Machines (AREA)
  • Liquid Crystal Substances (AREA)
ZA986904A 1997-08-01 1998-07-31 Process ZA986904B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9716161.6A GB9716161D0 (en) 1997-08-01 1997-08-01 Process

Publications (1)

Publication Number Publication Date
ZA986904B true ZA986904B (en) 1999-02-01

Family

ID=10816746

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA986904A ZA986904B (en) 1997-08-01 1998-07-31 Process

Country Status (32)

Country Link
US (2) US6372734B1 (no)
EP (2) EP1589008B1 (no)
JP (2) JP2001512109A (no)
KR (1) KR20010022241A (no)
CN (1) CN1125058C (no)
AT (2) ATE496037T1 (no)
AU (1) AU739255B2 (no)
BG (1) BG64796B1 (no)
BR (1) BR9811061A (no)
CA (1) CA2295792C (no)
CY (2) CY2200161T2 (no)
CZ (1) CZ299225B6 (no)
DE (4) DE69842104D1 (no)
EE (1) EE04550B1 (no)
ES (2) ES2296575T3 (no)
GB (2) GB9716161D0 (no)
HK (2) HK1029992A1 (no)
HU (1) HU228620B1 (no)
ID (1) ID24219A (no)
IL (1) IL133618A (no)
MY (1) MY120999A (no)
NO (1) NO20000484L (no)
NZ (1) NZ501914A (no)
PL (1) PL338384A1 (no)
PT (2) PT1589008E (no)
RU (1) RU2224754C2 (no)
SI (2) SI1000043T1 (no)
SK (1) SK287145B6 (no)
TR (1) TR200000848T2 (no)
TW (1) TW533207B (no)
WO (1) WO1999006381A1 (no)
ZA (1) ZA986904B (no)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003080065A1 (en) * 2002-03-20 2003-10-02 Teva Pharmaceutical Industries Ltd. Crystalline forms of quetiapine hemifumarate
WO2004076431A1 (en) * 2003-02-22 2004-09-10 Teva Pharmaceutical Industries Ltd. Synthesis of quetiapine and pharmaceutically acceptable salts thereof
WO2004078735A1 (en) * 2003-03-03 2004-09-16 Hetero Drugs Limited Novel polymorphs of quetiapine fumarate
WO2004089957A1 (en) * 2003-04-07 2004-10-21 Hetero Drugs Limited A novel crystalline form of dorzolamide hydrochloride
ES2223294B2 (es) 2003-08-08 2005-10-01 Vita Cientifica, S.L. Procedimiento de preparacion de un compuesto farmaceuticamente activo.
US20060081361A1 (en) * 2004-09-13 2006-04-20 Gabbey Lawrence W Oil cooler with integral filter
WO2006035293A1 (en) * 2004-09-27 2006-04-06 Ranbaxy Laboratories Limited Polymorphic forms of quetiapine hemifumarate
WO2006056772A2 (en) * 2004-11-23 2006-06-01 Pliva Hrvatska D.O.O. Salts of quetiapine
GB0425729D0 (en) * 2004-11-23 2004-12-22 Pliva Res & Dev Ltd Heterocyclic compounds
ES2234447B1 (es) * 2005-03-07 2006-03-01 Union Quimico-Farmaceutica S.A. Procedimiento para la obtencion de un derivado de 11-(4-sustituido-1-piperazinil)dibenzo(b,f)(1,4)tiazepina.
JP2008502707A (ja) 2005-04-14 2008-01-31 テバ ファーマシューティカル インダストリーズ リミティド クエチアピンフマレートの調製方法
US20070072840A1 (en) * 2005-05-30 2007-03-29 Pandya Bhargav Polymorphic forms of quetiapine
WO2007036599A1 (en) 2005-09-30 2007-04-05 Fermion Oy New crystallization process of quetiapine hemifumarate
WO2007048870A1 (en) * 2005-10-28 2007-05-03 Fermion Oy Quetiapine hemifumarate purification by crystallization
EP1951693A4 (en) * 2005-11-18 2012-05-30 Astrazeneca Ab SOLID FORMULATIONS
JP2009516708A (ja) * 2005-11-18 2009-04-23 アストラゼネカ・アクチエボラーグ 液体製剤
EP1951257A4 (en) * 2005-11-18 2008-11-05 Astrazeneca Ab CRYSTALLINE FORMS
US8389510B2 (en) * 2005-11-18 2013-03-05 Astrazeneca Ab Crystalline forms
CN101360724A (zh) * 2005-11-18 2009-02-04 阿斯利康公司 盐形式
CZ300451B6 (cs) * 2006-07-03 2009-05-20 Farmak, A. S. Zpusob prípravy solí 2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanolu (quetiapinu) a jejich cištení
WO2008066620A2 (en) * 2006-10-20 2008-06-05 Concert Pharmaceuticals Inc. Dibenzothiazepine derivatives
DE602007009036D1 (de) 2007-02-14 2010-10-21 Lesvi Laboratorios Sl Pharmazeutische Zusammensetzungen mit Quetiapinfumarat
US20080241949A1 (en) * 2007-03-29 2008-10-02 Vinod Kumar Kansal Process for preparing quetiapine fumarate
WO2009004480A2 (en) * 2007-05-07 2009-01-08 Actavis Group Ptc Ehf Quetiapine salts and their polymorphs
US20090082334A1 (en) * 2007-09-25 2009-03-26 Protia, Llc Deuterium-enriched quetiapine
CN101889000B (zh) * 2007-12-05 2012-11-28 詹森药业有限公司 二苯并氮杂*和二苯并氧氮杂*trpa1激动剂
DK2262486T3 (da) 2008-08-01 2013-03-25 Krka Tovarna Zdravil D D Novo Mesto Quetiapin sammensætning
US20100069356A1 (en) * 2008-09-17 2010-03-18 Auspex Pharmaceuticals, Inc. Dibenzothiazepine modulators of dopamine, alpha adrenergic, and serotonin receptors
JP2012519683A (ja) 2009-03-04 2012-08-30 ランバクシー ラボラトリーズ リミテッド フマル酸クエチアピンの調製方法
EP3789500A1 (en) 2011-08-12 2021-03-10 QIAGEN GmbH Method for isolating nucleic acids

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE787249A (fr) 1971-08-05 1973-02-05 Squibb & Sons Inc Derives amino d'acides pyrazolopyridine carboxyliques, leurs esters et les sels de ces composes, ainsi que leurs procedes de preparation
GB8607684D0 (en) * 1986-03-27 1986-04-30 Ici America Inc Thiazepine compounds
GB8705574D0 (en) 1987-03-10 1987-04-15 Ici Plc Preparation of thiazepine compound

Also Published As

Publication number Publication date
CA2295792A1 (en) 1999-02-11
WO1999006381A1 (en) 1999-02-11
TR200000848T2 (tr) 2000-08-21
CA2295792C (en) 2007-04-17
BR9811061A (pt) 2000-09-19
KR20010022241A (ko) 2001-03-15
GB9814882D0 (en) 1998-09-09
GB9716161D0 (en) 1997-10-08
JP2009102345A (ja) 2009-05-14
CZ299225B6 (cs) 2008-05-21
EE200000062A (et) 2000-10-16
CN1125058C (zh) 2003-10-22
SK1302000A3 (en) 2000-06-12
US20020147186A1 (en) 2002-10-10
MY120999A (en) 2005-12-30
PT1589008E (pt) 2011-03-23
DE05011169T1 (de) 2008-11-06
SI1000043T1 (sl) 2010-01-29
ES2296575T1 (es) 2008-05-01
NO20000484D0 (no) 2000-01-31
BG64796B1 (bg) 2006-04-28
CY2200162T2 (el) 2010-07-28
US6372734B1 (en) 2002-04-16
PT1000043E (pt) 2009-11-30
EP1589008B1 (en) 2011-01-19
EE04550B1 (et) 2005-10-17
HK1081962A1 (en) 2006-05-26
HUP0002663A2 (hu) 2001-09-28
AU8549898A (en) 1999-02-22
EP1000043A1 (en) 2000-05-17
ES2296568T1 (es) 2008-05-01
TW533207B (en) 2003-05-21
CY2200161T2 (el) 2010-07-28
EP1000043B1 (en) 2009-10-07
NZ501914A (en) 2001-09-28
HK1029992A1 (en) 2001-04-20
DE69842104D1 (de) 2011-03-03
DE69841216D1 (de) 2009-11-19
HU228620B1 (en) 2013-04-29
EP1589008A1 (en) 2005-10-26
NO20000484L (no) 2000-03-16
RU2224754C2 (ru) 2004-02-27
SI1589008T1 (sl) 2011-04-29
ES2296575T3 (es) 2010-02-05
BG104176A (en) 2000-08-31
DE98936529T1 (de) 2008-11-20
AU739255B2 (en) 2001-10-04
CN1265101A (zh) 2000-08-30
ATE444959T1 (de) 2009-10-15
CZ2000341A3 (cs) 2000-05-17
IL133618A (en) 2004-02-08
IL133618A0 (en) 2001-04-30
HUP0002663A3 (en) 2001-10-29
SK287145B6 (sk) 2010-01-07
PL338384A1 (en) 2000-10-23
ES2296568T3 (es) 2011-05-06
ID24219A (id) 2000-07-13
ATE496037T1 (de) 2011-02-15
JP2001512109A (ja) 2001-08-21

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