SI1589008T1 - Kristalinični dibenzotiazepinski derivat in njegova uporaba kot antipsihotično sredstvo - Google Patents

Kristalinični dibenzotiazepinski derivat in njegova uporaba kot antipsihotično sredstvo

Info

Publication number
SI1589008T1
SI1589008T1 SI9830929T SI9830929T SI1589008T1 SI 1589008 T1 SI1589008 T1 SI 1589008T1 SI 9830929 T SI9830929 T SI 9830929T SI 9830929 T SI9830929 T SI 9830929T SI 1589008 T1 SI1589008 T1 SI 1589008T1
Authority
SI
Slovenia
Prior art keywords
crystalline
füä1
ethylü
dibenzoäb
hydroxyethoxy
Prior art date
Application number
SI9830929T
Other languages
English (en)
Inventor
Evan William Snape
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of SI1589008T1 publication Critical patent/SI1589008T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D281/16—[b, f]-condensed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurosurgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Glass Compositions (AREA)
  • Iron Core Of Rotating Electric Machines (AREA)
  • Liquid Crystal Substances (AREA)
SI9830929T 1997-08-01 1998-07-28 Kristalinični dibenzotiazepinski derivat in njegova uporaba kot antipsihotično sredstvo SI1589008T1 (sl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9716161.6A GB9716161D0 (en) 1997-08-01 1997-08-01 Process
EP05011169A EP1589008B1 (en) 1997-08-01 1998-07-28 A crystalline dibenzothiazepine derivative and its use as an antipsychotic agent

Publications (1)

Publication Number Publication Date
SI1589008T1 true SI1589008T1 (sl) 2011-04-29

Family

ID=10816746

Family Applications (2)

Application Number Title Priority Date Filing Date
SI9830929T SI1589008T1 (sl) 1997-08-01 1998-07-28 Kristalinični dibenzotiazepinski derivat in njegova uporaba kot antipsihotično sredstvo
SI9830923T SI1000043T1 (sl) 1997-08-01 1998-07-28 Kristalinični dibenzotiazepinski derivat in njegova uporaba kot antipsihotično sredstvo

Family Applications After (1)

Application Number Title Priority Date Filing Date
SI9830923T SI1000043T1 (sl) 1997-08-01 1998-07-28 Kristalinični dibenzotiazepinski derivat in njegova uporaba kot antipsihotično sredstvo

Country Status (32)

Country Link
US (2) US6372734B1 (sl)
EP (2) EP1000043B1 (sl)
JP (2) JP2001512109A (sl)
KR (1) KR20010022241A (sl)
CN (1) CN1125058C (sl)
AT (2) ATE496037T1 (sl)
AU (1) AU739255B2 (sl)
BG (1) BG64796B1 (sl)
BR (1) BR9811061A (sl)
CA (1) CA2295792C (sl)
CY (2) CY2200162T2 (sl)
CZ (1) CZ299225B6 (sl)
DE (4) DE69842104D1 (sl)
EE (1) EE04550B1 (sl)
ES (2) ES2296575T3 (sl)
GB (2) GB9716161D0 (sl)
HK (2) HK1029992A1 (sl)
HU (1) HU228620B1 (sl)
ID (1) ID24219A (sl)
IL (1) IL133618A (sl)
MY (1) MY120999A (sl)
NO (1) NO20000484L (sl)
NZ (1) NZ501914A (sl)
PL (1) PL338384A1 (sl)
PT (2) PT1589008E (sl)
RU (1) RU2224754C2 (sl)
SI (2) SI1589008T1 (sl)
SK (1) SK287145B6 (sl)
TR (1) TR200000848T2 (sl)
TW (1) TW533207B (sl)
WO (1) WO1999006381A1 (sl)
ZA (1) ZA986904B (sl)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2000141A1 (en) * 2002-03-20 2008-12-10 Teva Pharmaceutical Industries Ltd. Methods for preparing crystalline quetiapine hemifumarate
US7071331B2 (en) 2003-02-22 2006-07-04 Teva Pharmaceutical Industries Ltd. Synthesis of quetiapine and pharmaceutically acceptable salts thereof
US7238686B2 (en) * 2003-03-03 2007-07-03 Hetero Drugs Limited Polymorphs of quetiapine fumarate
EP1611138A1 (en) 2003-04-07 2006-01-04 Hetero Drugs Limited A novel crystalline form of dorzolamide hydrochloride
ES2223294B2 (es) 2003-08-08 2005-10-01 Vita Cientifica, S.L. Procedimiento de preparacion de un compuesto farmaceuticamente activo.
US20060081361A1 (en) * 2004-09-13 2006-04-20 Gabbey Lawrence W Oil cooler with integral filter
WO2006035293A1 (en) * 2004-09-27 2006-04-06 Ranbaxy Laboratories Limited Polymorphic forms of quetiapine hemifumarate
WO2006056772A2 (en) * 2004-11-23 2006-06-01 Pliva Hrvatska D.O.O. Salts of quetiapine
GB0425729D0 (en) * 2004-11-23 2004-12-22 Pliva Res & Dev Ltd Heterocyclic compounds
ES2234447B1 (es) * 2005-03-07 2006-03-01 Union Quimico-Farmaceutica S.A. Procedimiento para la obtencion de un derivado de 11-(4-sustituido-1-piperazinil)dibenzo(b,f)(1,4)tiazepina.
JP2008502707A (ja) 2005-04-14 2008-01-31 テバ ファーマシューティカル インダストリーズ リミティド クエチアピンフマレートの調製方法
US20070072840A1 (en) * 2005-05-30 2007-03-29 Pandya Bhargav Polymorphic forms of quetiapine
EP1928849A1 (en) 2005-09-30 2008-06-11 Fermion Oy New crystallization process of quetiapine hemifumarate
EP1948628A1 (en) * 2005-10-28 2008-07-30 Fermion Oy Quetiapine hemifumarate purification by crystallization
US8389510B2 (en) * 2005-11-18 2013-03-05 Astrazeneca Ab Crystalline forms
CN101360502B (zh) * 2005-11-18 2012-03-14 阿斯利康公司 结晶形式
US20090215744A1 (en) * 2005-11-18 2009-08-27 Astrazeneca Ab Solid Formulations
CN101360503A (zh) * 2005-11-18 2009-02-04 阿斯利康公司 液体制剂
JP2009516705A (ja) * 2005-11-18 2009-04-23 アストラゼネカ・アクチエボラーグ 塩の形態
CZ300451B6 (cs) * 2006-07-03 2009-05-20 Farmak, A. S. Zpusob prípravy solí 2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanolu (quetiapinu) a jejich cištení
WO2008066620A2 (en) * 2006-10-20 2008-06-05 Concert Pharmaceuticals Inc. Dibenzothiazepine derivatives
ATE480227T1 (de) 2007-02-14 2010-09-15 Lesvi Laboratorios Sl Pharmazeutische zusammensetzungen mit quetiapinfumarat
EP2144892A2 (en) * 2007-03-29 2010-01-20 Teva Pharmaceutical Industries Ltd. Improved process for preparing quetiapine fumarate
WO2009004480A2 (en) * 2007-05-07 2009-01-08 Actavis Group Ptc Ehf Quetiapine salts and their polymorphs
US20090082334A1 (en) * 2007-09-25 2009-03-26 Protia, Llc Deuterium-enriched quetiapine
EP2229364B1 (en) * 2007-12-05 2015-02-25 Janssen Pharmaceutica, N.V. Dibenzoazepine and dibenzooxazepine trpa1 agonists
SI2262486T1 (sl) 2008-08-01 2013-04-30 Krka, Tovarna Zdravil, D.D., Novo Mesto Sestavek kvetiapina
US20100069356A1 (en) * 2008-09-17 2010-03-18 Auspex Pharmaceuticals, Inc. Dibenzothiazepine modulators of dopamine, alpha adrenergic, and serotonin receptors
US20120071649A1 (en) 2009-03-04 2012-03-22 Ranbaxy Laboratories Limited Process for the preparation of quetiapine fumarate
WO2013024072A1 (en) 2011-08-12 2013-02-21 Qiagen Gmbh Method for isolating nucleic acids

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE787249A (fr) 1971-08-05 1973-02-05 Squibb & Sons Inc Derives amino d'acides pyrazolopyridine carboxyliques, leurs esters et les sels de ces composes, ainsi que leurs procedes de preparation
GB8607684D0 (en) * 1986-03-27 1986-04-30 Ici America Inc Thiazepine compounds
GB8705574D0 (en) * 1987-03-10 1987-04-15 Ici Plc Preparation of thiazepine compound

Also Published As

Publication number Publication date
AU8549898A (en) 1999-02-22
ZA986904B (en) 1999-02-01
EP1589008B1 (en) 2011-01-19
TR200000848T2 (tr) 2000-08-21
HU228620B1 (en) 2013-04-29
ES2296575T1 (es) 2008-05-01
EE200000062A (et) 2000-10-16
SK287145B6 (sk) 2010-01-07
SI1000043T1 (sl) 2010-01-29
JP2001512109A (ja) 2001-08-21
BG64796B1 (bg) 2006-04-28
DE69841216D1 (de) 2009-11-19
NO20000484L (no) 2000-03-16
GB9814882D0 (en) 1998-09-09
CZ2000341A3 (cs) 2000-05-17
AU739255B2 (en) 2001-10-04
ID24219A (id) 2000-07-13
CN1125058C (zh) 2003-10-22
CA2295792A1 (en) 1999-02-11
BR9811061A (pt) 2000-09-19
TW533207B (en) 2003-05-21
DE98936529T1 (de) 2008-11-20
DE69842104D1 (de) 2011-03-03
EP1000043A1 (en) 2000-05-17
HUP0002663A3 (en) 2001-10-29
JP2009102345A (ja) 2009-05-14
IL133618A (en) 2004-02-08
IL133618A0 (en) 2001-04-30
EP1589008A1 (en) 2005-10-26
ES2296575T3 (es) 2010-02-05
ATE444959T1 (de) 2009-10-15
US6372734B1 (en) 2002-04-16
KR20010022241A (ko) 2001-03-15
CY2200162T2 (el) 2010-07-28
ES2296568T3 (es) 2011-05-06
CY2200161T2 (el) 2010-07-28
HK1029992A1 (en) 2001-04-20
EE04550B1 (et) 2005-10-17
ES2296568T1 (es) 2008-05-01
SK1302000A3 (en) 2000-06-12
PT1000043E (pt) 2009-11-30
PL338384A1 (en) 2000-10-23
CZ299225B6 (cs) 2008-05-21
NZ501914A (en) 2001-09-28
RU2224754C2 (ru) 2004-02-27
HUP0002663A2 (hu) 2001-09-28
CN1265101A (zh) 2000-08-30
HK1081962A1 (en) 2006-05-26
ATE496037T1 (de) 2011-02-15
EP1000043B1 (en) 2009-10-07
DE05011169T1 (de) 2008-11-06
NO20000484D0 (no) 2000-01-31
CA2295792C (en) 2007-04-17
GB9716161D0 (en) 1997-10-08
WO1999006381A1 (en) 1999-02-11
US20020147186A1 (en) 2002-10-10
MY120999A (en) 2005-12-30
BG104176A (en) 2000-08-31
PT1589008E (pt) 2011-03-23

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