ZA9811434B - Protein expression in baculovirus vector expression systems - Google Patents
Protein expression in baculovirus vector expression systemsInfo
- Publication number
- ZA9811434B ZA9811434B ZA9811434A ZA9811434A ZA9811434B ZA 9811434 B ZA9811434 B ZA 9811434B ZA 9811434 A ZA9811434 A ZA 9811434A ZA 9811434 A ZA9811434 A ZA 9811434A ZA 9811434 B ZA9811434 B ZA 9811434B
- Authority
- ZA
- South Africa
- Prior art keywords
- expression
- baculovirus vector
- systems
- protein expression
- protein
- Prior art date
Links
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- 241000701447 unidentified baculovirus Species 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/14011—Baculoviridae
- C12N2710/14111—Nucleopolyhedrovirus, e.g. autographa californica nucleopolyhedrovirus
- C12N2710/14141—Use of virus, viral particle or viral elements as a vector
- C12N2710/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24311—Pestivirus, e.g. bovine viral diarrhea virus
- C12N2770/24322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24311—Pestivirus, e.g. bovine viral diarrhea virus
- C12N2770/24334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Plant Pathology (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP97203989A EP0924298A1 (en) | 1997-12-18 | 1997-12-18 | Protein expression in baculovirus vector expression systems |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA9811434B true ZA9811434B (en) | 1999-06-16 |
Family
ID=8229076
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA9811434A ZA9811434B (en) | 1997-12-18 | 1998-12-14 | Protein expression in baculovirus vector expression systems |
Country Status (22)
Country | Link |
---|---|
US (2) | US6555346B1 (da) |
EP (2) | EP0924298A1 (da) |
JP (2) | JP4220126B2 (da) |
KR (3) | KR100682171B1 (da) |
CN (2) | CN101130073A (da) |
AR (1) | AR015499A1 (da) |
AT (1) | ATE324456T1 (da) |
AU (1) | AU750514B2 (da) |
BR (1) | BR9813692B1 (da) |
CA (2) | CA2635158A1 (da) |
CO (1) | CO4820445A1 (da) |
DE (1) | DE69834346T2 (da) |
DK (1) | DK1049788T3 (da) |
ES (1) | ES2267203T3 (da) |
HK (1) | HK1037670A1 (da) |
HU (1) | HU228122B1 (da) |
IL (2) | IL136815A0 (da) |
NZ (1) | NZ505322A (da) |
TW (1) | TWI225094B (da) |
UY (1) | UY25315A1 (da) |
WO (1) | WO1999031257A2 (da) |
ZA (1) | ZA9811434B (da) |
Families Citing this family (99)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5545553A (en) * | 1994-09-26 | 1996-08-13 | The Rockefeller University | Glycosyltransferases for biosynthesis of oligosaccharides, and genes encoding them |
EP0924298A1 (en) | 1997-12-18 | 1999-06-23 | Stichting Instituut voor Dierhouderij en Diergezondheid (ID-DLO) | Protein expression in baculovirus vector expression systems |
EP1035205A1 (en) | 1999-03-08 | 2000-09-13 | Stichting Dienst Landbouwkundig Onderzoek | Non-spreading pestivirus |
AUPQ233799A0 (en) * | 1999-08-19 | 1999-09-09 | Minister For Agriculture, Minister For Land And Water Conservation For And On Behalf Of The State Of New South Wales | Recombinant sub-unit vaccine |
CN1338310A (zh) * | 2000-08-10 | 2002-03-06 | 清华大学 | 一种猪瘟病毒表位疫苗及其制备方法 |
WO2002070667A2 (en) * | 2001-03-05 | 2002-09-12 | Transtech Pharma, Inc. | High level insect expression of rage proteins |
US7696163B2 (en) | 2001-10-10 | 2010-04-13 | Novo Nordisk A/S | Erythropoietin: remodeling and glycoconjugation of erythropoietin |
US7214660B2 (en) | 2001-10-10 | 2007-05-08 | Neose Technologies, Inc. | Erythropoietin: remodeling and glycoconjugation of erythropoietin |
US7795210B2 (en) * | 2001-10-10 | 2010-09-14 | Novo Nordisk A/S | Protein remodeling methods and proteins/peptides produced by the methods |
US7157277B2 (en) | 2001-11-28 | 2007-01-02 | Neose Technologies, Inc. | Factor VIII remodeling and glycoconjugation of Factor VIII |
US7173003B2 (en) * | 2001-10-10 | 2007-02-06 | Neose Technologies, Inc. | Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF |
US8008252B2 (en) * | 2001-10-10 | 2011-08-30 | Novo Nordisk A/S | Factor VII: remodeling and glycoconjugation of Factor VII |
US7399613B2 (en) * | 2001-10-10 | 2008-07-15 | Neose Technologies, Inc. | Sialic acid nucleotide sugars |
US7179617B2 (en) * | 2001-10-10 | 2007-02-20 | Neose Technologies, Inc. | Factor IX: remolding and glycoconjugation of Factor IX |
MXPA04012496A (es) * | 2002-06-21 | 2005-09-12 | Novo Nordisk Healthcare Ag | Glicoformos del factor vii pegilados. |
JP4708027B2 (ja) * | 2002-10-01 | 2011-06-22 | ノバルティス バクシンズ アンド ダイアグノスティックス,インコーポレーテッド | 抗癌組成物および抗感染疾患組成物ならびにこれらを使用する方法 |
CA2519092C (en) * | 2003-03-14 | 2014-08-05 | Neose Technologies, Inc. | Branched water-soluble polymers and their conjugates |
EP1615945B1 (en) * | 2003-04-09 | 2011-09-28 | BioGeneriX AG | Glycopegylation methods and proteins/peptides produced by the methods |
US8791070B2 (en) | 2003-04-09 | 2014-07-29 | Novo Nordisk A/S | Glycopegylated factor IX |
WO2004091499A2 (en) * | 2003-04-09 | 2004-10-28 | Neose Technologies, Inc. | Intracellular formation of peptide conjugates |
WO2006127896A2 (en) | 2005-05-25 | 2006-11-30 | Neose Technologies, Inc. | Glycopegylated factor ix |
ATE540055T1 (de) | 2003-05-09 | 2012-01-15 | Biogenerix Ag | Zusammensetzungen und verfahren zur herstellung von glykosylierungsmutanten des menschlichen wachstumshormons |
US9005625B2 (en) | 2003-07-25 | 2015-04-14 | Novo Nordisk A/S | Antibody toxin conjugates |
US20080305992A1 (en) | 2003-11-24 | 2008-12-11 | Neose Technologies, Inc. | Glycopegylated erythropoietin |
CA2547140A1 (en) * | 2003-11-24 | 2005-06-09 | Neose Technologies, Inc. | Glycopegylated erythropoietin |
US8633157B2 (en) * | 2003-11-24 | 2014-01-21 | Novo Nordisk A/S | Glycopegylated erythropoietin |
US20080318850A1 (en) * | 2003-12-03 | 2008-12-25 | Neose Technologies, Inc. | Glycopegylated Factor Ix |
NZ547554A (en) * | 2003-12-03 | 2009-09-25 | Biogenerix Ag | Glycopegylated granulocyte colony stimulating factor |
US20060040856A1 (en) | 2003-12-03 | 2006-02-23 | Neose Technologies, Inc. | Glycopegylated factor IX |
US7956032B2 (en) * | 2003-12-03 | 2011-06-07 | Novo Nordisk A/S | Glycopegylated granulocyte colony stimulating factor |
CN101072789B (zh) * | 2004-01-08 | 2013-05-15 | 生物种属学股份公司 | 肽的o-连接的糖基化 |
NZ548256A (en) | 2004-02-02 | 2010-02-26 | Ambrx Inc | Modified human four helical bundle polypeptides and their uses |
KR20070034512A (ko) | 2004-06-18 | 2007-03-28 | 암브룩스, 인코포레이티드 | 신규 항원-결합 폴리펩티드 및 이의 용도 |
US20080300173A1 (en) | 2004-07-13 | 2008-12-04 | Defrees Shawn | Branched Peg Remodeling and Glycosylation of Glucagon-Like Peptides-1 [Glp-1] |
WO2006031811A2 (en) * | 2004-09-10 | 2006-03-23 | Neose Technologies, Inc. | Glycopegylated interferon alpha |
HUE026826T2 (en) | 2004-10-29 | 2016-07-28 | Ratiopharm Gmbh | Modeling and glycopegylation of fibroblast growth factor (FGF) |
WO2006073846A2 (en) | 2004-12-22 | 2006-07-13 | Ambrx, Inc. | Methods for expression and purification of recombinant human growth hormone |
CN102719366B (zh) | 2004-12-22 | 2014-07-16 | Ambrx公司 | 氨酰基-tRNA合成酶的组合物及其用途 |
BRPI0519170A8 (pt) | 2004-12-22 | 2018-05-08 | Ambrx Inc | formulações de hormônio de crescimento humano que compreendem um aminoácido não naturalmente codificado |
CN103690936A (zh) | 2004-12-22 | 2014-04-02 | Ambrx公司 | 经修饰的人类生长激素 |
CA2927595C (en) | 2004-12-22 | 2023-01-31 | Ambrx, Inc. | Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides |
JP2008526864A (ja) * | 2005-01-06 | 2008-07-24 | ネオス テクノロジーズ インコーポレイテッド | 糖断片を用いる糖結合 |
ES2449195T3 (es) | 2005-01-10 | 2014-03-18 | Ratiopharm Gmbh | Factor estimulante de colonias de granulocitos glicopegilado |
WO2006078645A2 (en) * | 2005-01-19 | 2006-07-27 | Neose Technologies, Inc. | Heterologous polypeptide expression using low multiplicity of infection of viruses |
EP1866427A4 (en) * | 2005-03-30 | 2010-09-01 | Novo Nordisk As | MANUFACTURING PROCESS FOR THE PRODUCTION OF CULTIVE PEPTIDES IN CELL LINES OF INSECTS |
WO2006121569A2 (en) * | 2005-04-08 | 2006-11-16 | Neose Technologies, Inc. | Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants |
EP1888098A2 (en) * | 2005-05-25 | 2008-02-20 | Neose Technologies, Inc. | Glycopegylated erythropoietin formulations |
AU2006255122B2 (en) | 2005-06-03 | 2010-10-21 | Ambrx, Inc. | Improved human interferon molecules and their uses |
US20070105755A1 (en) * | 2005-10-26 | 2007-05-10 | Neose Technologies, Inc. | One pot desialylation and glycopegylation of therapeutic peptides |
US20090305967A1 (en) * | 2005-08-19 | 2009-12-10 | Novo Nordisk A/S | Glycopegylated factor vii and factor viia |
US20090048440A1 (en) * | 2005-11-03 | 2009-02-19 | Neose Technologies, Inc. | Nucleotide Sugar Purification Using Membranes |
AU2006315347A1 (en) | 2005-11-16 | 2007-05-24 | Ambrx, Inc. | Methods and compositions comprising non-natural amino acids |
CN100497612C (zh) * | 2006-01-25 | 2009-06-10 | 中国农业科学院生物技术研究所 | 一种耐高温乳糖酶的制备方法 |
CU23544A1 (es) | 2006-02-28 | 2010-06-17 | Ct Ingenieria Genetica Biotech | Antígenos vacunales quiméricos contra el virus de la peste porcina clásica |
ES2516694T3 (es) * | 2006-07-21 | 2014-10-31 | Ratiopharm Gmbh | Glicosilación de péptidos a través de secuencias de glicosilación con unión en O |
WO2008030613A2 (en) | 2006-09-08 | 2008-03-13 | Ambrx, Inc. | Hybrid suppressor trna for vertebrate cells |
CA2663083A1 (en) | 2006-09-08 | 2008-03-13 | Ambrx, Inc. | Modified human plasma polypeptide or fc scaffolds and their uses |
US8969532B2 (en) * | 2006-10-03 | 2015-03-03 | Novo Nordisk A/S | Methods for the purification of polypeptide conjugates comprising polyalkylene oxide using hydrophobic interaction chromatography |
KR101556248B1 (ko) * | 2006-10-04 | 2015-09-30 | 노보 노르디스크 에이/에스 | 글리세롤이 연결된 페길화된 당 및 글리코펩티드 |
US20080207487A1 (en) * | 2006-11-02 | 2008-08-28 | Neose Technologies, Inc. | Manufacturing process for the production of polypeptides expressed in insect cell-lines |
WO2008121563A2 (en) | 2007-03-30 | 2008-10-09 | Ambrx, Inc. | Modified fgf-21 polypeptides and their uses |
PL2144923T3 (pl) | 2007-04-03 | 2013-12-31 | Biogenerix Ag | Sposoby leczenia z użyciem glikopegilowanego G-CSF |
NZ580686A (en) | 2007-05-02 | 2012-11-30 | Ambrx Inc | Modified interferon beta polypeptides and their uses |
US20090053167A1 (en) * | 2007-05-14 | 2009-02-26 | Neose Technologies, Inc. | C-, S- and N-glycosylation of peptides |
US20110177029A1 (en) * | 2007-06-04 | 2011-07-21 | Novo Nordisk A/S | O-linked glycosylation using n-acetylglucosaminyl transferases |
US9493499B2 (en) * | 2007-06-12 | 2016-11-15 | Novo Nordisk A/S | Process for the production of purified cytidinemonophosphate-sialic acid-polyalkylene oxide (CMP-SA-PEG) as modified nucleotide sugars via anion exchange chromatography |
US8207112B2 (en) * | 2007-08-29 | 2012-06-26 | Biogenerix Ag | Liquid formulation of G-CSF conjugate |
CN101152570B (zh) * | 2007-10-19 | 2010-11-24 | 清华大学 | 一种猪瘟病毒表位疫苗及其制备方法 |
NZ603812A (en) | 2007-11-20 | 2014-06-27 | Ambrx Inc | Modified insulin polypeptides and their uses |
CN103694337B (zh) | 2008-02-08 | 2016-03-02 | Ambrx公司 | 经修饰瘦素多肽和其用途 |
WO2009108806A1 (en) | 2008-02-27 | 2009-09-03 | Novo Nordisk A/S | Conjugated factor viii molecules |
EP3225248B1 (en) | 2008-07-23 | 2023-06-07 | Ambrx, Inc. | Modified bovine g-csf polypeptides and their uses |
TWI362416B (en) * | 2008-07-31 | 2012-04-21 | Mao Xing Biolog Technology Co Ltd | Yeast expressed classical swine fever virus glycoprotein e2 and use thereof |
CA2738033C (en) | 2008-09-26 | 2019-11-26 | Ambrx, Inc. | Non-natural amino acid replication-dependent microorganisms and vaccines |
CA2737026C (en) | 2008-09-26 | 2019-12-24 | Ambrx, Inc. | Modified animal erythropoietin polypeptides and their uses |
EP2202298A1 (en) | 2008-12-23 | 2010-06-30 | Stichting Dienst Landbouwkundig Onderzoek | Recombinant classical swine fever virus (CSFV) comprising a modified E2 protein and methods for generating said recombinant CSFV |
CN104017063A (zh) | 2009-12-21 | 2014-09-03 | Ambrx公司 | 经过修饰的猪促生长素多肽和其用途 |
MX349301B (es) | 2009-12-21 | 2017-07-21 | Ambrx Inc | Polipéptidos de somatotropina bovina modificados y sus usos. |
DK2605789T3 (da) | 2010-08-17 | 2019-09-16 | Ambrx Inc | Modificerede relaxinpolypeptider og anvendelser deraf |
US9567386B2 (en) | 2010-08-17 | 2017-02-14 | Ambrx, Inc. | Therapeutic uses of modified relaxin polypeptides |
TWI480288B (zh) | 2010-09-23 | 2015-04-11 | Lilly Co Eli | 牛顆粒細胞群落刺激因子及其變體之調配物 |
BR112014004261B8 (pt) * | 2011-08-24 | 2022-11-08 | Zoetis Llc | Diagnósticos de vacina melhorada |
JP6063563B2 (ja) * | 2012-06-12 | 2017-01-18 | オルタナティブ ジーン エクスプレッション エセ.エレ. | 宿主昆虫における組換えタンパク質の発現のためのバキュロウイルスdnaエレメント |
RU2619161C2 (ru) * | 2012-06-12 | 2017-05-12 | Альтернативе Гене Экспрессион С.Л. | Элементы рекомбинантной днк для экспрессии рекомбинантных белков в клетке-хозяине |
US9487971B2 (en) | 2013-03-15 | 2016-11-08 | Spectrum Brands, Inc. | Electro-mechanical locks with bezel turning function |
DE102013103336A1 (de) * | 2013-04-03 | 2014-10-09 | B. Braun Avitum Ag | Vorrichtung zur Identifizierung einer Dialysatorvorrichtung oder einer Komponente derselben, und hierfür verwendbare Sensorvorrichtung |
JP2015015931A (ja) * | 2013-07-12 | 2015-01-29 | 株式会社Umnファーマ | ウイルス様粒子を含む培養物の製造方法 |
CN105473712B (zh) * | 2013-08-30 | 2022-05-27 | 葛兰素史密丝克莱恩生物有限公司 | 在细胞培养物中大规模生产病毒 |
CN103882051B (zh) * | 2014-03-20 | 2016-04-06 | 北京市农林科学院 | 一种检测猪瘟病毒抗体的elisa方法及检测试剂盒 |
MX2017004947A (es) | 2014-10-24 | 2017-06-29 | Bristol Myers Squibb Co | Polipeptidos del factor de crecimiento de fibroblastos 2 (fgf-21) modificados y usos de los mismos. |
KR20170083249A (ko) * | 2016-01-08 | 2017-07-18 | 경상대학교산학협력단 | 곤충세포를 이용한 식물 유래 오스모틴 단백질의 대량 생산 방법 |
KR102670432B1 (ko) | 2017-02-08 | 2024-05-28 | 브리스톨-마이어스 스큅 컴퍼니 | 약동학적 인핸서를 포함하는 변형된 렐락신 폴리펩티드 및 그의 용도 |
AU2019290228A1 (en) | 2018-06-22 | 2021-01-28 | Asklepios Biopharmaceutical, Inc. | Vectors for gene delivery that persist within cells |
CN109182380B (zh) * | 2018-08-14 | 2022-06-03 | 浙江大学 | 杆状病毒表达的猪瘟e2亚单位疫苗的制备方法及应用 |
GB202013940D0 (en) | 2020-09-04 | 2020-10-21 | Synpromics Ltd | Regulatory nucleic acid sequences |
JP2023545731A (ja) | 2020-10-07 | 2023-10-31 | アスクレピオス バイオファーマシューティカル, インコーポレイテッド | 肢帯型2i(lgmd2i)を含むジストログリカノパチー障害を処置するためのフクチン関連タンパク質(fkrp)の治療的アデノ随伴ウイルス送達 |
CN112646840B (zh) * | 2020-12-25 | 2022-11-18 | 石河子大学 | 一种杆状病毒表达系统制备牛病毒性腹泻病毒e2蛋白的方法及应用 |
EP4377466A1 (en) * | 2021-07-28 | 2024-06-05 | BioMarin Pharmaceutical Inc. | Large scale adeno-associated virus production systems |
KR20240104204A (ko) | 2021-12-27 | 2024-07-04 | 덴카 주식회사 | 바큘로바이러스 발현계에 있어서의 단백질의 제조법 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA901719B (en) * | 1989-03-19 | 1991-01-30 | Akzo Nv | Hog cholera virus vaccine and diagnostics |
US5514634A (en) | 1991-11-06 | 1996-05-07 | Mobil Oil Corporation | High activity polyethylene catalysts |
WO1995035380A1 (en) * | 1994-06-17 | 1995-12-28 | Instituut Voor Dierhouderij En Diergezondheid | Nucleotide sequences of pestivirus strains, polypeptides encoded by these sequences and use thereof for diagnosis and prevention of pestivirus infections |
PT772632E (pt) * | 1994-12-20 | 2002-02-28 | Akzo Nobel Nv | Proteina estimuladora de celulas t de pestivirus |
WO1996025496A1 (en) * | 1995-02-17 | 1996-08-22 | Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) | PRODUCTION OF BIOLOGICALLY ACTIVE RECOMBINANT BOVINE FOLLICLE STIMULATING HORMONE (REC bFSH) IN THE BACULOVIRUS EXPRESSION SYSTEM |
EP0924298A1 (en) | 1997-12-18 | 1999-06-23 | Stichting Instituut voor Dierhouderij en Diergezondheid (ID-DLO) | Protein expression in baculovirus vector expression systems |
-
1997
- 1997-12-18 EP EP97203989A patent/EP0924298A1/en not_active Withdrawn
-
1998
- 1998-12-14 ZA ZA9811434A patent/ZA9811434B/xx unknown
- 1998-12-17 IL IL13681598A patent/IL136815A0/xx not_active IP Right Cessation
- 1998-12-17 JP JP2000539155A patent/JP4220126B2/ja not_active Expired - Fee Related
- 1998-12-17 DK DK98962690T patent/DK1049788T3/da active
- 1998-12-17 CA CA002635158A patent/CA2635158A1/en not_active Abandoned
- 1998-12-17 AU AU17865/99A patent/AU750514B2/en not_active Ceased
- 1998-12-17 WO PCT/NL1998/000717 patent/WO1999031257A2/en active Application Filing
- 1998-12-17 ES ES98962690T patent/ES2267203T3/es not_active Expired - Lifetime
- 1998-12-17 AT AT98962690T patent/ATE324456T1/de active
- 1998-12-17 AR ARP980106452A patent/AR015499A1/es active IP Right Grant
- 1998-12-17 CA CA002315248A patent/CA2315248C/en not_active Expired - Fee Related
- 1998-12-17 KR KR1020057022071A patent/KR100682171B1/ko not_active IP Right Cessation
- 1998-12-17 EP EP98962690A patent/EP1049788B1/en not_active Expired - Lifetime
- 1998-12-17 KR KR1020057022070A patent/KR100796871B1/ko not_active IP Right Cessation
- 1998-12-17 KR KR1020007006746A patent/KR100699609B1/ko not_active IP Right Cessation
- 1998-12-17 NZ NZ505322A patent/NZ505322A/xx not_active IP Right Cessation
- 1998-12-17 CN CNA2006101534938A patent/CN101130073A/zh active Pending
- 1998-12-17 CN CNB988136848A patent/CN1283801C/zh not_active Expired - Fee Related
- 1998-12-17 BR BRPI9813692-5A patent/BR9813692B1/pt not_active IP Right Cessation
- 1998-12-17 HU HU0101136A patent/HU228122B1/hu not_active IP Right Cessation
- 1998-12-17 DE DE69834346T patent/DE69834346T2/de not_active Expired - Lifetime
- 1998-12-18 UY UY25315A patent/UY25315A1/es not_active Application Discontinuation
- 1998-12-18 CO CO98075475A patent/CO4820445A1/es unknown
-
1999
- 1999-03-16 TW TW087121320A patent/TWI225094B/zh not_active IP Right Cessation
-
2000
- 2000-06-16 US US09/596,105 patent/US6555346B1/en not_active Expired - Fee Related
-
2001
- 2001-10-30 HK HK01107561A patent/HK1037670A1/xx not_active IP Right Cessation
-
2003
- 2003-02-27 US US10/376,994 patent/US6919085B2/en not_active Expired - Fee Related
-
2007
- 2007-02-20 IL IL181468A patent/IL181468A/en not_active IP Right Cessation
- 2007-05-07 JP JP2007122898A patent/JP4336723B2/ja not_active Expired - Fee Related
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HUP0101136A3 (en) | Protein expression in baculovirus vector expression systems | |
GB9718609D0 (en) | Fusion protein | |
IL133582A0 (en) | Mammalian neuro-growth factor like protein | |
GB9703681D0 (en) | Protein complemention | |
GB9719879D0 (en) | Protein | |
EP1018551A4 (en) | MEGSINE PROTEIN | |
GB9718110D0 (en) | Peptides | |
ZA985999B (en) | Protein kinases and uses thereof | |
EP1012262A4 (en) | HFLP PROTEIN HFLP | |
GB9701710D0 (en) | Mammalian protein | |
ZA984322B (en) | Sucrose-binding proteins | |
GB9700154D0 (en) | Peptides | |
GB9715064D0 (en) | Protein expression | |
PL339259A1 (en) | Gonadothropin expression in dictostelium | |
GB9720784D0 (en) | Protein | |
EP0996457A4 (en) | PEPTIDES RELEASERS OF F.S.H. | |
GB2334257B (en) | Rectroviral vectors | |
GB2331752B (en) | Vectors | |
GB9720633D0 (en) | BHV-2 vector | |
GB9703103D0 (en) | Protein | |
GB9719670D0 (en) | Protein | |
GB9720785D0 (en) | Protein | |
GB9707822D0 (en) | Proteins | |
GB9722727D0 (en) | Proteins | |
GB9707499D0 (en) | Proteins |