ZA908599B - A method for isolating biologically active compounds - Google Patents

A method for isolating biologically active compounds

Info

Publication number
ZA908599B
ZA908599B ZA908599A ZA908599A ZA908599B ZA 908599 B ZA908599 B ZA 908599B ZA 908599 A ZA908599 A ZA 908599A ZA 908599 A ZA908599 A ZA 908599A ZA 908599 B ZA908599 B ZA 908599B
Authority
ZA
South Africa
Prior art keywords
biologically active
active compounds
isolating biologically
isolating
factor viii
Prior art date
Application number
ZA908599A
Other languages
English (en)
Inventor
Per Kaersgaard
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of ZA908599B publication Critical patent/ZA908599B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cephalosporin Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Networks Using Active Elements (AREA)
  • Amplifiers (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • External Artificial Organs (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Separation By Low-Temperature Treatments (AREA)
ZA908599A 1989-11-09 1990-10-26 A method for isolating biologically active compounds ZA908599B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK562189A DK162233C (da) 1989-11-09 1989-11-09 Fremgangsmaade til isolering af faktor viii fra blodplasma og pharmaceutisk praeparat indeholdende den saaledes isolerede fator viii

Publications (1)

Publication Number Publication Date
ZA908599B true ZA908599B (en) 1991-07-31

Family

ID=8144000

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA908599A ZA908599B (en) 1989-11-09 1990-10-26 A method for isolating biologically active compounds

Country Status (26)

Country Link
US (1) US5245014A (fi)
EP (1) EP0524172B1 (fi)
JP (1) JP2509407B2 (fi)
CN (1) CN1044121C (fi)
AT (1) ATE118508T1 (fi)
AU (1) AU631471B2 (fi)
BG (1) BG61231B1 (fi)
CA (1) CA2073012C (fi)
CZ (1) CZ537190A3 (fi)
DE (1) DE69017050T2 (fi)
DK (1) DK162233C (fi)
ES (1) ES2068404T3 (fi)
FI (1) FI103510B (fi)
HU (1) HU214905B (fi)
IE (1) IE66836B1 (fi)
IL (1) IL96277A (fi)
NO (1) NO180741C (fi)
NZ (1) NZ236004A (fi)
PL (1) PL164894B1 (fi)
PT (1) PT95830B (fi)
RU (1) RU2055593C1 (fi)
SK (1) SK537190A3 (fi)
UA (1) UA29421C2 (fi)
WO (1) WO1991007438A1 (fi)
YU (1) YU47524B (fi)
ZA (1) ZA908599B (fi)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0399321B1 (en) * 1989-05-24 1993-06-23 Miles Inc. Gel filtration of heat treated factor viii
US5888974A (en) * 1992-04-07 1999-03-30 Emory University Hybrid human/animal factor VIII
US6180371B1 (en) 1996-06-26 2001-01-30 Emory University Modified factor VIII
US5859204A (en) * 1992-04-07 1999-01-12 Emory University Modified factor VIII
US5659017A (en) * 1995-11-07 1997-08-19 Alpha Therapeutic Corporation Anion exchange process for the purification of Factor VIII
US6458563B1 (en) 1996-06-26 2002-10-01 Emory University Modified factor VIII
US7560107B2 (en) 1996-06-26 2009-07-14 Emory University Modified factor VIII
US6531577B1 (en) * 1997-12-15 2003-03-11 Hemasure Denmark A/S von Willebrand factor (vWF)-containing preparation, process for preparing vWF-containing preparations, and use of such preparations
US6290527B1 (en) * 1998-07-03 2001-09-18 Nippon Telegraph And Telephone Corp. Nippon telegraph and telephone corporation
CZ307715B6 (cs) 1999-02-22 2019-03-06 University Of Connecticut Způsob lyofilizace vodné farmaceutické formulace faktoru VIII prosté albuminu
JP2002348300A (ja) * 1999-04-12 2002-12-04 Fujimori Kogyo Co Ltd 血液凝固第ｖｉｉｉ因子および血液凝固第ｖｉｉｉ因子／フォン・ビルブラント因子複合体の精製方法
AUPR638801A0 (en) * 2001-07-13 2001-08-09 Life Therapeutics Limited Factor viii separation
ES2449044T3 (es) 2004-05-03 2014-03-18 Emory University Procedimiento de administración de fVIII sin dominio B porcino
US20080176789A1 (en) * 2004-08-27 2008-07-24 Novc Nordisk Healthcare A/G Purification of Factor Xlll Polypeptides From Biological Materials
US20060226086A1 (en) * 2005-04-08 2006-10-12 Robinson Thomas C Centrifuge for blood processing systems
TR201900207T4 (tr) 2008-11-07 2019-02-21 Baxalta GmbH Faktör VIII Formülasyonları
EP3133157B1 (en) * 2010-03-30 2019-05-08 Octapharma AG A process for purifying vitamin k dependent proteins
RU2445974C2 (ru) * 2010-04-26 2012-03-27 Учреждение Российской академии медицинских наук Гематологический научный центр ГНЦ РАМН Способ получения концентрата фактора viii из плазмы крови человека
SG190136A1 (en) 2010-11-05 2013-07-31 Baxter Int A new variant of antihemophilic factor viii having increased specific activity
EP2652491B1 (en) 2010-12-15 2017-11-29 Baxalta GmbH Eluate collection using conductivity gradient
CN103506080A (zh) * 2012-06-19 2014-01-15 汪志友 一种用于分离纯化凝血因子viii的介质及其制备方法
EP2902787B1 (en) * 2012-09-28 2018-03-28 Chugai Seiyaku Kabushiki Kaisha Method for evaluating blood coagulation reaction
US9663553B2 (en) * 2014-01-29 2017-05-30 Hemarus Therapeutics Limited Integrated process for the production of therapeutics (human albumin, immunoglobulins, clotting factor VIII and clotting factor IX) from human plasma

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4495175A (en) * 1982-08-05 1985-01-22 University Of Rochester Preparation of highly purified human antihemophilic factor
US4543210A (en) * 1984-10-04 1985-09-24 Miles Laboratories, Inc. Process for producing a high purity antihemophilic factor concentrate
DK525384D0 (da) * 1984-11-05 1984-11-05 Nordisk Insulinlab Praeparat paa basis af faktor viii til behandling af haemofili a inhibitorpatienter samt fremgangsmaade til fremstilling af et saadan praeparat
US4847362A (en) * 1985-02-01 1989-07-11 New York University Method for purifying antihemophilic factor
US4675385A (en) * 1985-03-27 1987-06-23 Alpha Therapeutic Corporation Isolation of human plasma procoagulant protein factor VIII from biological factors
US4758657A (en) * 1985-07-11 1988-07-19 Armour Pharmaceutical Company Method of purifying Factor VIII:C
AT391808B (de) * 1986-11-03 1990-12-10 Immuno Ag Verfahren zur herstellung einer faktor viii (ahf)-haeltigen fraktion
ATE112287T1 (de) * 1987-12-21 1994-10-15 Miles Inc Faktor viii- gelfiltration.
WO1989009784A1 (en) * 1988-04-08 1989-10-19 Commonwealth Serum Laboratories Commission Production of heat-stable factor viii concentrate
EP0399321B1 (en) * 1989-05-24 1993-06-23 Miles Inc. Gel filtration of heat treated factor viii

Also Published As

Publication number Publication date
ATE118508T1 (de) 1995-03-15
NO921839L (no) 1992-07-08
PT95830B (pt) 1997-11-28
FI922105A (fi) 1992-05-08
BG96316A (bg) 1993-12-24
UA29421C2 (uk) 2000-11-15
IL96277A (en) 1995-07-31
PT95830A (pt) 1991-09-30
FI922105A0 (fi) 1992-05-08
NO180741C (no) 1997-06-11
FI103510B1 (fi) 1999-07-15
WO1991007438A1 (en) 1991-05-30
YU210590A (sh) 1993-05-28
YU47524B (sh) 1995-10-03
IE66836B1 (en) 1996-02-07
DE69017050D1 (de) 1995-03-23
CN1044121C (zh) 1999-07-14
IE904022A1 (en) 1991-05-22
SK278640B6 (en) 1997-12-10
DK562189A (da) 1991-05-10
PL287703A1 (en) 1991-12-02
NO180741B (no) 1997-03-03
DK162233B (da) 1991-09-30
AU631471B2 (en) 1992-11-26
EP0524172B1 (en) 1995-02-15
RU2055593C1 (ru) 1996-03-10
DK162233C (da) 1992-03-16
DE69017050T2 (de) 1995-06-14
HU9201551D0 (en) 1992-08-28
CA2073012A1 (en) 1991-05-10
SK537190A3 (en) 1997-12-10
NO921839D0 (no) 1992-05-08
PL164894B1 (pl) 1994-10-31
CZ537190A3 (cs) 1998-05-13
HU214905B (hu) 1998-07-28
HUT60511A (en) 1992-09-28
AU6747090A (en) 1991-06-13
JPH05501557A (ja) 1993-03-25
DK562189D0 (da) 1989-11-09
CA2073012C (en) 1996-03-19
EP0524172A1 (en) 1993-01-27
ES2068404T3 (es) 1995-04-16
NZ236004A (en) 1991-11-26
FI103510B (fi) 1999-07-15
IL96277A0 (en) 1991-08-16
JP2509407B2 (ja) 1996-06-19
CN1051732A (zh) 1991-05-29
US5245014A (en) 1993-09-14
BG61231B1 (en) 1997-03-31

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