ZA869181B - Prodrugs of rapamycin - Google Patents

Prodrugs of rapamycin

Info

Publication number
ZA869181B
ZA869181B ZA869181A ZA869181A ZA869181B ZA 869181 B ZA869181 B ZA 869181B ZA 869181 A ZA869181 A ZA 869181A ZA 869181 A ZA869181 A ZA 869181A ZA 869181 B ZA869181 B ZA 869181B
Authority
ZA
South Africa
Prior art keywords
sub
prodrugs
rapamycin
carbon atoms
formulawherein
Prior art date
Application number
ZA869181A
Other languages
English (en)
Inventor
Valentino John Stella
Paul Edwin Kennedy
Original Assignee
Univ Kansas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Kansas filed Critical Univ Kansas
Publication of ZA869181B publication Critical patent/ZA869181B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/18—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
ZA869181A 1985-12-06 1986-12-04 Prodrugs of rapamycin ZA869181B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/806,152 US4650803A (en) 1985-12-06 1985-12-06 Prodrugs of rapamycin

Publications (1)

Publication Number Publication Date
ZA869181B true ZA869181B (en) 1988-07-27

Family

ID=25193443

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA869181A ZA869181B (en) 1985-12-06 1986-12-04 Prodrugs of rapamycin

Country Status (16)

Country Link
US (1) US4650803A (fr)
EP (1) EP0227355B1 (fr)
JP (2) JPH0670066B2 (fr)
KR (2) KR940004072B1 (fr)
AT (1) ATE74134T1 (fr)
AU (1) AU583439B2 (fr)
CA (2) CA1273920A (fr)
DE (1) DE3684574D1 (fr)
DK (2) DK169409B1 (fr)
ES (1) ES2032750T3 (fr)
GB (1) GB2183647A (fr)
GR (1) GR3004530T3 (fr)
HU (1) HU198054B (fr)
IE (1) IE64506B1 (fr)
PT (1) PT83843B (fr)
ZA (1) ZA869181B (fr)

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EP0227355A2 (fr) 1987-07-01
JPH0670066B2 (ja) 1994-09-07
EP0227355B1 (fr) 1992-03-25
AU6608086A (en) 1987-06-11
PT83843B (pt) 1989-01-17
HU198054B (en) 1989-07-28
KR940004073B1 (ko) 1994-05-11
JPH0747593B2 (ja) 1995-05-24
PT83843A (en) 1987-01-01
US4650803A (en) 1987-03-17
IE64506B1 (en) 1995-08-09
DE3684574D1 (de) 1992-04-30
DK34793A (da) 1993-03-25
EP0227355A3 (en) 1988-10-12
GB2183647B (fr) 1989-10-18
KR870006072A (ko) 1987-07-09
JPS62215592A (ja) 1987-09-22
DK584886D0 (da) 1986-12-05
GR3004530T3 (fr) 1993-04-28
GB8628994D0 (en) 1987-01-14
JPH06263765A (ja) 1994-09-20
DK34793D0 (da) 1993-03-25
GB2183647A (en) 1987-06-10
DK584886A (da) 1987-06-07
CA1312076C (fr) 1992-12-29
DK169409B1 (da) 1994-10-24
ES2032750T3 (es) 1993-03-01
IE863198L (en) 1987-06-06
CA1273920A (fr) 1990-09-11
ATE74134T1 (de) 1992-04-15
KR940004072B1 (ko) 1994-05-11
AU583439B2 (en) 1989-04-27
DK170750B1 (da) 1996-01-08

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