ES8607265A1 - Un procedimiento para la preparacion de nuevos derivados de aminoalcoholes - Google Patents

Un procedimiento para la preparacion de nuevos derivados de aminoalcoholes

Info

Publication number
ES8607265A1
ES8607265A1 ES544919A ES544919A ES8607265A1 ES 8607265 A1 ES8607265 A1 ES 8607265A1 ES 544919 A ES544919 A ES 544919A ES 544919 A ES544919 A ES 544919A ES 8607265 A1 ES8607265 A1 ES 8607265A1
Authority
ES
Spain
Prior art keywords
atoms
branched
alkynyloxy
piperazin
propyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES544919A
Other languages
English (en)
Other versions
ES544919A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Riom Lab C E R M Rl Cerm S A
Original Assignee
Riom Lab C E R M Rl Cerm S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Riom Lab C E R M Rl Cerm S A filed Critical Riom Lab C E R M Rl Cerm S A
Publication of ES544919A0 publication Critical patent/ES544919A0/es
Publication of ES8607265A1 publication Critical patent/ES8607265A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE AMINOALCOHOLES Y DE SUS SALES DE ADICION DE ACIDOS FISIOLOGICAMENTE COMPATIBLES, DE FORMULA (I), EN LA QUE X ES HIDROGENO O HALOGENO; R1 Y R4 REPRESENTAN HIDROGENO O ALQUILO INFERIOR; R5 ES ALQUILO INFERIOR O FENILO; R2 Y R3 PUEDEN SER VARIOS TIPOS DE RADICALES. CONSISTE EN LA REACCION DE UN COMPUESTO DE FORMULA (II), O UNA DE SUS SALES, CON UN COMPUESTO DE FORMULA (III), EN LAS QUE TODOS LOS SIMBOLOS TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I). LA REACCION SE LLEVA A CABO EN UN DISOLVENTE ORGANICO ANHIDRO, TAL COMO ETANOL ABSOLUTO, A LA TEMPERATURA AMBIENTE. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO DE LA ANGINA.
ES544919A 1983-09-15 1985-07-05 Un procedimiento para la preparacion de nuevos derivados de aminoalcoholes Expired ES8607265A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8314720A FR2552083B1 (fr) 1983-09-15 1983-09-15 Derives de (alkynyloxy-3 hydroxy-2-propyl)-4 piperazinyl-1 n-phenyl acetamide, leur preparation et leur application en therapeutique

Publications (2)

Publication Number Publication Date
ES544919A0 ES544919A0 (es) 1986-05-16
ES8607265A1 true ES8607265A1 (es) 1986-05-16

Family

ID=9292262

Family Applications (2)

Application Number Title Priority Date Filing Date
ES535899A Expired ES8602724A1 (es) 1983-09-15 1984-09-13 Un procedimiento para la preparacion de nuevos derivados de aminoalcoholes.
ES544919A Expired ES8607265A1 (es) 1983-09-15 1985-07-05 Un procedimiento para la preparacion de nuevos derivados de aminoalcoholes

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES535899A Expired ES8602724A1 (es) 1983-09-15 1984-09-13 Un procedimiento para la preparacion de nuevos derivados de aminoalcoholes.

Country Status (14)

Country Link
EP (1) EP0143016B1 (es)
JP (1) JPS60142972A (es)
KR (1) KR850002477A (es)
AT (1) ATE28639T1 (es)
AU (1) AU572888B2 (es)
DE (1) DE3465085D1 (es)
DK (1) DK439384A (es)
ES (2) ES8602724A1 (es)
FI (1) FI77243C (es)
FR (1) FR2552083B1 (es)
GR (1) GR80359B (es)
HU (1) HU192994B (es)
PT (1) PT79214B (es)
ZA (1) ZA846937B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR0108592A (pt) * 2000-02-22 2004-06-29 Cv Therapeutics Inc Compostos de piperazina substituìda
US6677336B2 (en) 2000-02-22 2004-01-13 Cv Therapeutics, Inc. Substituted piperazine compounds
US6552023B2 (en) 2000-02-22 2003-04-22 Cv Therapeutics, Inc. Aralkyl substituted piperazine compounds
US6451798B2 (en) 2000-02-22 2002-09-17 Cv Therapeutics, Inc. Substituted alkyl piperazine derivatives
US6693099B2 (en) * 2000-10-17 2004-02-17 The Procter & Gamble Company Substituted piperazine compounds optionally containing a quinolyl moiety for treating multidrug resistance
EP2142506B1 (en) * 2007-03-30 2013-10-16 Council of Scientific & Industrial Research Novel benzophenone hybrids as potential anticancer agents and a process for the preparation thereof
JP6077344B2 (ja) * 2013-03-12 2017-02-08 花王株式会社 ピペラジン誘導体を含む漂白剤組成物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3951979A (en) * 1972-04-13 1976-04-20 Roland Yves Mauvernary New amino propanediol derivatives
FR2173869B1 (es) * 1972-04-13 1975-12-26 Cerm Cent Europ Rech Mauvernay
FR2403330A1 (fr) * 1977-06-16 1979-04-13 Fabre Sa Pierre Nouveaux derives de benzoyl-2-chloro-4-glycinanilides substitues, leur procede de preparation et leur application en tant que medicaments

Also Published As

Publication number Publication date
JPS60142972A (ja) 1985-07-29
HUT35253A (en) 1985-06-28
FR2552083A1 (fr) 1985-03-22
ZA846937B (en) 1985-04-24
ES544919A0 (es) 1986-05-16
ATE28639T1 (de) 1987-08-15
FI843617L (fi) 1985-03-16
ES535899A0 (es) 1985-12-01
EP0143016B1 (fr) 1987-07-29
FI77243B (fi) 1988-10-31
EP0143016A1 (fr) 1985-05-29
PT79214A (en) 1984-10-01
DK439384A (da) 1985-03-16
AU3286184A (en) 1985-03-21
DK439384D0 (da) 1984-09-14
KR850002477A (ko) 1985-05-13
HU192994B (en) 1987-08-28
ES8602724A1 (es) 1985-12-01
PT79214B (en) 1986-08-22
DE3465085D1 (en) 1987-09-03
AU572888B2 (en) 1988-05-19
FR2552083B1 (fr) 1986-05-09
FI77243C (fi) 1989-02-10
GR80359B (en) 1985-01-11
FI843617A0 (fi) 1984-09-14

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