FI843617L - 4-(2-alkynyloxi-2-hydroxipropyl)- piperazin-1-yl-n-fenyl-acetamidderivat. - Google Patents

4-(2-alkynyloxi-2-hydroxipropyl)- piperazin-1-yl-n-fenyl-acetamidderivat.

Info

Publication number
FI843617L
FI843617L FI843617A FI843617A FI843617L FI 843617 L FI843617 L FI 843617L FI 843617 A FI843617 A FI 843617A FI 843617 A FI843617 A FI 843617A FI 843617 L FI843617 L FI 843617L
Authority
FI
Finland
Prior art keywords
atoms
phenyl
branched
alkyl radical
hydroxipropyl
Prior art date
Application number
FI843617A
Other languages
English (en)
Other versions
FI843617A0 (fi
FI77243C (fi
FI77243B (fi
Inventor
Michel Combourieu
Jean-Claude Laigle
Jean-Francois Reyjal
Marie-Paule Landes
Original Assignee
Cerm Cent Europ Rech Mauvernay
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cerm Cent Europ Rech Mauvernay filed Critical Cerm Cent Europ Rech Mauvernay
Publication of FI843617A0 publication Critical patent/FI843617A0/fi
Publication of FI843617L publication Critical patent/FI843617L/fi
Application granted granted Critical
Publication of FI77243B publication Critical patent/FI77243B/fi
Publication of FI77243C publication Critical patent/FI77243C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI843617A 1983-09-15 1984-09-14 Foerfarande foer framstaellning av terapeutiskt anvaendbara 4-(3-alkynyloxi-2-hydroxipropyl)piperazin-1- yl-n-fenylacetamidderivat. FI77243C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8314720 1983-09-15
FR8314720A FR2552083B1 (fr) 1983-09-15 1983-09-15 Derives de (alkynyloxy-3 hydroxy-2-propyl)-4 piperazinyl-1 n-phenyl acetamide, leur preparation et leur application en therapeutique

Publications (4)

Publication Number Publication Date
FI843617A0 FI843617A0 (fi) 1984-09-14
FI843617L true FI843617L (fi) 1985-03-16
FI77243B FI77243B (fi) 1988-10-31
FI77243C FI77243C (fi) 1989-02-10

Family

ID=9292262

Family Applications (1)

Application Number Title Priority Date Filing Date
FI843617A FI77243C (fi) 1983-09-15 1984-09-14 Foerfarande foer framstaellning av terapeutiskt anvaendbara 4-(3-alkynyloxi-2-hydroxipropyl)piperazin-1- yl-n-fenylacetamidderivat.

Country Status (14)

Country Link
EP (1) EP0143016B1 (fi)
JP (1) JPS60142972A (fi)
KR (1) KR850002477A (fi)
AT (1) ATE28639T1 (fi)
AU (1) AU572888B2 (fi)
DE (1) DE3465085D1 (fi)
DK (1) DK439384A (fi)
ES (2) ES8602724A1 (fi)
FI (1) FI77243C (fi)
FR (1) FR2552083B1 (fi)
GR (1) GR80359B (fi)
HU (1) HU192994B (fi)
PT (1) PT79214B (fi)
ZA (1) ZA846937B (fi)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6451798B2 (en) 2000-02-22 2002-09-17 Cv Therapeutics, Inc. Substituted alkyl piperazine derivatives
EP1259493A2 (en) * 2000-02-22 2002-11-27 Cv Therapeutics, Inc. Substituted piperazine compounds
US6552023B2 (en) 2000-02-22 2003-04-22 Cv Therapeutics, Inc. Aralkyl substituted piperazine compounds
US6677336B2 (en) 2000-02-22 2004-01-13 Cv Therapeutics, Inc. Substituted piperazine compounds
US6693099B2 (en) * 2000-10-17 2004-02-17 The Procter & Gamble Company Substituted piperazine compounds optionally containing a quinolyl moiety for treating multidrug resistance
EP2142506B1 (en) * 2007-03-30 2013-10-16 Council of Scientific & Industrial Research Novel benzophenone hybrids as potential anticancer agents and a process for the preparation thereof
JP6077344B2 (ja) * 2013-03-12 2017-02-08 花王株式会社 ピペラジン誘導体を含む漂白剤組成物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2173869B1 (fi) * 1972-04-13 1975-12-26 Cerm Cent Europ Rech Mauvernay
US3951979A (en) * 1972-04-13 1976-04-20 Roland Yves Mauvernary New amino propanediol derivatives
FR2403330A1 (fr) * 1977-06-16 1979-04-13 Fabre Sa Pierre Nouveaux derives de benzoyl-2-chloro-4-glycinanilides substitues, leur procede de preparation et leur application en tant que medicaments

Also Published As

Publication number Publication date
HUT35253A (en) 1985-06-28
AU572888B2 (en) 1988-05-19
DK439384A (da) 1985-03-16
FI843617A0 (fi) 1984-09-14
JPS60142972A (ja) 1985-07-29
PT79214A (en) 1984-10-01
FI77243C (fi) 1989-02-10
GR80359B (en) 1985-01-11
FI77243B (fi) 1988-10-31
ES535899A0 (es) 1985-12-01
FR2552083A1 (fr) 1985-03-22
AU3286184A (en) 1985-03-21
ES8602724A1 (es) 1985-12-01
PT79214B (en) 1986-08-22
KR850002477A (ko) 1985-05-13
ZA846937B (en) 1985-04-24
DK439384D0 (da) 1984-09-14
HU192994B (en) 1987-08-28
DE3465085D1 (en) 1987-09-03
ES544919A0 (es) 1986-05-16
ES8607265A1 (es) 1986-05-16
FR2552083B1 (fr) 1986-05-09
EP0143016A1 (fr) 1985-05-29
EP0143016B1 (fr) 1987-07-29
ATE28639T1 (de) 1987-08-15

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Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: RIOM LABORATOIRES - C.E.R.M.