ZA867716B - Novel pharmacological compounds - Google Patents

Novel pharmacological compounds

Info

Publication number
ZA867716B
ZA867716B ZA867716A ZA867716A ZA867716B ZA 867716 B ZA867716 B ZA 867716B ZA 867716 A ZA867716 A ZA 867716A ZA 867716 A ZA867716 A ZA 867716A ZA 867716 B ZA867716 B ZA 867716B
Authority
ZA
South Africa
Prior art keywords
pharmacological compounds
novel pharmacological
compounds
novel
chem
Prior art date
Application number
ZA867716A
Other languages
English (en)
Inventor
Tomas Boerje Alminger
Haa Kan Sigurd Larsson
Per Lennart Lindberg
Gunnel Elizabeth Sunden
Original Assignee
Haessle Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Haessle Ab filed Critical Haessle Ab
Publication of ZA867716B publication Critical patent/ZA867716B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
  • Indole Compounds (AREA)
ZA867716A 1985-10-29 1986-10-09 Novel pharmacological compounds ZA867716B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8505112A SE8505112D0 (sv) 1985-10-29 1985-10-29 Novel pharmacological compounds

Publications (1)

Publication Number Publication Date
ZA867716B true ZA867716B (en) 1987-05-27

Family

ID=20361960

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA867716A ZA867716B (en) 1985-10-29 1986-10-09 Novel pharmacological compounds

Country Status (31)

Country Link
US (1) US5021433A (OSRAM)
EP (2) EP0233284B1 (OSRAM)
JP (2) JPH0780874B2 (OSRAM)
KR (1) KR950009858B1 (OSRAM)
CN (1) CN1022487C (OSRAM)
AT (1) ATE79619T1 (OSRAM)
AU (1) AU598491B2 (OSRAM)
CS (1) CS272767B2 (OSRAM)
DD (1) DD252375A5 (OSRAM)
DE (1) DE3686483T2 (OSRAM)
DK (1) DK320587D0 (OSRAM)
EG (1) EG17753A (OSRAM)
ES (1) ES2051696T3 (OSRAM)
FI (1) FI91151C (OSRAM)
GR (1) GR3006177T3 (OSRAM)
HU (1) HU198474B (OSRAM)
IE (1) IE59167B1 (OSRAM)
IL (1) IL80437A0 (OSRAM)
IS (1) IS1564B (OSRAM)
JO (1) JO1502B1 (OSRAM)
LT (1) LTIP1681A (OSRAM)
LV (1) LV10270B (OSRAM)
MY (1) MY101791A (OSRAM)
NO (1) NO171365C (OSRAM)
NZ (1) NZ218028A (OSRAM)
PH (1) PH25319A (OSRAM)
PL (1) PL150240B1 (OSRAM)
PT (1) PT83647B (OSRAM)
SE (1) SE8505112D0 (OSRAM)
WO (1) WO1987002668A1 (OSRAM)
ZA (1) ZA867716B (OSRAM)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ222495A (en) * 1986-11-21 1991-04-26 Haessle Ab Benzimidazole derivatives and pharmaceutical compositions
KR920003928B1 (ko) * 1988-09-20 1992-05-18 히사미쯔세이야꾸 가부시기가이샤 신규의 디벤즈[b,e]옥세핀유도체
IE64199B1 (en) * 1988-12-22 1995-07-12 Haessle Ab Compound with gastric acid inhibitory effect and process for its preparation
SE8804629D0 (sv) * 1988-12-22 1988-12-22 Ab Haessle New therapeutically active compounds
US4965269A (en) * 1989-12-20 1990-10-23 Ab Hassle Therapeutically active chloro substituted benzimidazoles
US5049674A (en) * 1989-12-20 1991-09-17 Aktiebolaget Hassle Therapeutically active fluoro substituted benzimidazoles
US5274099A (en) * 1989-12-20 1993-12-28 Aktiebolaget Hassle Therapeutically active fluoro substituted benzimidazoles
JP3049367B2 (ja) * 1990-06-20 2000-06-05 アストラゼネカ・アクチエボラーグ ジアルコキシ−ピリジニル−ベンズイミダゾール誘導体、その製造方法およびそれを含む医薬
SE9002206D0 (sv) 1990-06-20 1990-06-20 Haessle Ab New compounds
ES2048109B1 (es) * 1992-07-20 1994-12-16 Espanola Prod Quimicos Procedimiento de preparacion de nuevos derivados piperidicos del bencimidazol.
WO1995032957A1 (en) * 1994-05-27 1995-12-07 Astra Aktiebolag Novel ethoxycarbonyloxymethyl derivatives of substituted benzimidazoles
DE69905171T2 (de) * 1998-08-10 2003-11-20 Dept Of Veterans Affairs Washi Prodrugs für proton-pump-inhibitoren
US6093734A (en) * 1998-08-10 2000-07-25 Partnership Of Michael E. Garst, George Sachs, And Jai Moo Shin Prodrugs of proton pump inhibitors
US6852739B1 (en) 1999-02-26 2005-02-08 Nitromed Inc. Methods using proton pump inhibitors and nitric oxide donors
US6369087B1 (en) * 1999-08-26 2002-04-09 Robert R. Whittle Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
EP1334971A4 (en) * 2000-10-12 2004-05-12 Takeda Chemical Industries Ltd BENZIMIDAZOLE COMPOUNDS, METHOD FOR THE PRODUCTION AND USE THEREOF
US20040248941A1 (en) * 2001-09-25 2004-12-09 Keiji Kamiyama Benzimidazone compound, process for producing the same, and use thereof
WO2003105845A1 (en) * 2002-06-14 2003-12-24 Takeda Chemical Industries, Ltd. Prodrugs of imidazole derivatives, for use as proton pump inhibitors in the treatment of e.g. peptic ulcers
BR0312802A (pt) * 2002-07-19 2005-04-19 Michael E Garst Pró-drogas de inibidores de bombas de próton
CA2493618A1 (en) 2002-08-01 2004-02-12 Nitromed, Inc. Nitrosated proton pump inhibitors, compositions and methods of use
MY148805A (en) 2002-10-16 2013-05-31 Takeda Pharmaceutical Controlled release preparation
US8802139B2 (en) * 2003-06-26 2014-08-12 Intellipharmaceutics Corp. Proton pump-inhibitor-containing capsules which comprise subunits differently structured for a delayed release of the active ingredient
WO2005039640A1 (en) * 2003-10-03 2005-05-06 Allergan Inc. Compositions comprising trefoil factor family peptides and/or mucoadhesives and proton pump inhibitor prodrugs
US20050075371A1 (en) * 2003-10-03 2005-04-07 Allergan, Inc. Methods and compositions for the oral administration of prodrugs of proton pump inhibitors
US20070060621A1 (en) * 2004-02-18 2007-03-15 Hughes Patrick M Methods and compositions for the administration of prodrugs of proton pump inhibitors
EP1715854A2 (en) * 2004-02-18 2006-11-02 Allergan, Inc. Prodrugs for the intravenous administration of proton pump inhibitors
JP2007532677A (ja) * 2004-04-16 2007-11-15 サンタラス インコーポレイティッド プロトンポンプ阻害剤、緩衝剤、および運動促進薬の組み合わせ
PT1740571E (pt) 2004-04-28 2009-09-02 Hetero Drugs Ltd Processo para preparar compostos de piridinilmetil-1hbenzimidazol na forma enantiomericamente enriquecida ou como enantiómeros únicos
ES2338556T3 (es) * 2004-05-28 2010-05-10 Hetero Drugs Limited Sintesis estereoselectiva novedosa de sulfoxidos de benzimidazol.
US8394409B2 (en) * 2004-07-01 2013-03-12 Intellipharmaceutics Corp. Controlled extended drug release technology
US10624858B2 (en) 2004-08-23 2020-04-21 Intellipharmaceutics Corp Controlled release composition using transition coating, and method of preparing same
US10064828B1 (en) 2005-12-23 2018-09-04 Intellipharmaceutics Corp. Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems
WO2007112581A1 (en) * 2006-04-03 2007-10-11 Isa Odidi Controlled release delivery device comprising an organosol coat
US10960077B2 (en) 2006-05-12 2021-03-30 Intellipharmaceutics Corp. Abuse and alcohol resistant drug composition
US20100317689A1 (en) * 2006-09-19 2010-12-16 Garst Michael E Prodrugs of proton pump inhibitors including the 1h-imidazo[4,5-b] pyridine moiety
MX2009004475A (es) 2006-10-27 2009-08-12 Univ Missouri Composiciones que comprenden agentes acido labiles que inhiben la bomba de protones, por lo menos otro agente farmaceuticamente activo y metodos de uso de las misma.
US20080194307A1 (en) * 2007-02-13 2008-08-14 Jeff Sanger Sports-based game of chance
CN101980700A (zh) 2008-02-20 2011-02-23 密苏里大学董事会 包含奥美拉唑和兰索拉唑以及缓冲剂的组合的组合物及其使用方法
EP2521545B1 (en) 2010-01-07 2019-11-27 Alkermes Pharma Ireland Limited Prodrugs of heteroaromatic compounds

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE418966B (sv) * 1974-02-18 1981-07-06 Haessle Ab Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan
US4045564A (en) * 1974-02-18 1977-08-30 Ab Hassle Benzimidazole derivatives useful as gastric acid secretion inhibitors
SE416649B (sv) * 1974-05-16 1981-01-26 Haessle Ab Forfarande for framstellning av foreningar som paverkar magsyrasekretionen
IN148930B (OSRAM) * 1977-09-19 1981-07-25 Hoffmann La Roche
SE7804231L (sv) * 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
US4359465A (en) * 1980-07-28 1982-11-16 The Upjohn Company Methods for treating gastrointestinal inflammation
CH644116A5 (de) * 1980-08-21 1984-07-13 Hoffmann La Roche Imidazolderivate.
SE8300736D0 (sv) * 1983-02-11 1983-02-11 Haessle Ab Novel pharmacologically active compounds
IL75400A (en) * 1984-06-16 1988-10-31 Byk Gulden Lomberg Chem Fab Dialkoxypyridine methyl(sulfinyl or sulfonyl)benzimidazoles,processes for the preparation thereof and pharmaceutical compositions containing the same
AU568441B2 (en) * 1984-09-24 1987-12-24 Upjohn Company, The 2-(pyridylalkenesulfinyl) benzimidazole derivatives
ZA856671B (en) * 1984-09-24 1986-04-30 Upjohn Co N-substituted derivatives of 2-(pyridylaklenesulfinyl)benzimidazoles as gastric antisecretory agents

Also Published As

Publication number Publication date
EP0233284B1 (en) 1992-08-19
FI872864L (fi) 1987-06-29
ATE79619T1 (de) 1992-09-15
AU6542986A (en) 1987-05-19
EP0233284A1 (en) 1987-08-26
JO1502B1 (en) 1989-01-25
PT83647A (en) 1986-11-01
PT83647B (pt) 1989-05-31
CS782686A2 (en) 1990-05-14
NO171365C (no) 1993-03-03
DD252375A5 (de) 1987-12-16
LTIP1681A (en) 1995-09-25
SE8505112D0 (sv) 1985-10-29
LV10270B (en) 1995-04-20
AU598491B2 (en) 1990-06-28
JPH0826014B2 (ja) 1996-03-13
ES2051696T3 (es) 1994-07-01
DE3686483T2 (de) 1993-02-04
KR870700620A (ko) 1987-12-30
IS3156A7 (is) 1987-04-30
PL150240B1 (en) 1990-05-31
EP0221041A3 (en) 1987-10-28
HUT43843A (en) 1987-12-28
NZ218028A (en) 1990-02-26
NO872686D0 (no) 1987-06-26
IE59167B1 (en) 1994-01-12
IL80437A0 (en) 1987-01-30
CN1022487C (zh) 1993-10-20
PL262105A1 (en) 1988-08-18
CS272767B2 (en) 1991-02-12
LV10270A (lv) 1994-10-20
PH25319A (OSRAM) 1991-04-30
JPH0780874B2 (ja) 1995-08-30
FI91151B (fi) 1994-02-15
DE3686483D1 (de) 1992-09-24
NO171365B (no) 1992-11-23
MY101791A (en) 1992-01-31
GR3006177T3 (OSRAM) 1993-06-21
IS1564B (is) 1994-12-13
US5021433A (en) 1991-06-04
CN86107595A (zh) 1987-07-08
JPH07188216A (ja) 1995-07-25
WO1987002668A1 (en) 1987-05-07
IE862805L (en) 1987-04-29
KR950009858B1 (ko) 1995-08-29
DK320587A (da) 1987-06-24
DK320587D0 (da) 1987-06-24
EG17753A (en) 1991-12-30
JPS63501151A (ja) 1988-04-28
NO872686L (no) 1987-06-26
FI872864A0 (fi) 1987-06-29
EP0221041A2 (en) 1987-05-06
FI91151C (sv) 1994-05-25
HU198474B (en) 1989-10-30

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