IL80437A0 - Benzimidazole derivatives and pharmaceutical compositions containing them - Google Patents

Benzimidazole derivatives and pharmaceutical compositions containing them

Info

Publication number
IL80437A0
IL80437A0 IL80437A IL8043786A IL80437A0 IL 80437 A0 IL80437 A0 IL 80437A0 IL 80437 A IL80437 A IL 80437A IL 8043786 A IL8043786 A IL 8043786A IL 80437 A0 IL80437 A0 IL 80437A0
Authority
IL
Israel
Prior art keywords
pharmaceutical compositions
compositions containing
benzimidazole derivatives
compounds
benzimidazole
Prior art date
Application number
IL80437A
Other languages
English (en)
Original Assignee
Haessle Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Haessle Ab filed Critical Haessle Ab
Publication of IL80437A0 publication Critical patent/IL80437A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
IL80437A 1985-10-29 1986-10-28 Benzimidazole derivatives and pharmaceutical compositions containing them IL80437A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8505112A SE8505112D0 (sv) 1985-10-29 1985-10-29 Novel pharmacological compounds

Publications (1)

Publication Number Publication Date
IL80437A0 true IL80437A0 (en) 1987-01-30

Family

ID=20361960

Family Applications (1)

Application Number Title Priority Date Filing Date
IL80437A IL80437A0 (en) 1985-10-29 1986-10-28 Benzimidazole derivatives and pharmaceutical compositions containing them

Country Status (31)

Country Link
US (1) US5021433A (OSRAM)
EP (2) EP0233284B1 (OSRAM)
JP (2) JPH0780874B2 (OSRAM)
KR (1) KR950009858B1 (OSRAM)
CN (1) CN1022487C (OSRAM)
AT (1) ATE79619T1 (OSRAM)
AU (1) AU598491B2 (OSRAM)
CS (1) CS272767B2 (OSRAM)
DD (1) DD252375A5 (OSRAM)
DE (1) DE3686483T2 (OSRAM)
DK (1) DK320587D0 (OSRAM)
EG (1) EG17753A (OSRAM)
ES (1) ES2051696T3 (OSRAM)
FI (1) FI91151C (OSRAM)
GR (1) GR3006177T3 (OSRAM)
HU (1) HU198474B (OSRAM)
IE (1) IE59167B1 (OSRAM)
IL (1) IL80437A0 (OSRAM)
IS (1) IS1564B (OSRAM)
JO (1) JO1502B1 (OSRAM)
LT (1) LTIP1681A (OSRAM)
LV (1) LV10270B (OSRAM)
MY (1) MY101791A (OSRAM)
NO (1) NO171365C (OSRAM)
NZ (1) NZ218028A (OSRAM)
PH (1) PH25319A (OSRAM)
PL (1) PL150240B1 (OSRAM)
PT (1) PT83647B (OSRAM)
SE (1) SE8505112D0 (OSRAM)
WO (1) WO1987002668A1 (OSRAM)
ZA (1) ZA867716B (OSRAM)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ234564A (en) * 1986-11-21 1991-04-26 Haessle Ab 1-substituted benzimidazoles and pharmaceutical compositions
EP0436025A4 (en) * 1988-09-20 1991-09-11 Hisamitsu Pharmaceutical Co. Inc. Novel dibenz b,e)oxepin derivatives
IE64199B1 (en) * 1988-12-22 1995-07-12 Haessle Ab Compound with gastric acid inhibitory effect and process for its preparation
SE8804629D0 (sv) * 1988-12-22 1988-12-22 Ab Haessle New therapeutically active compounds
US5274099A (en) * 1989-12-20 1993-12-28 Aktiebolaget Hassle Therapeutically active fluoro substituted benzimidazoles
US4965269A (en) * 1989-12-20 1990-10-23 Ab Hassle Therapeutically active chloro substituted benzimidazoles
US5049674A (en) * 1989-12-20 1991-09-17 Aktiebolaget Hassle Therapeutically active fluoro substituted benzimidazoles
WO1991019712A1 (en) * 1990-06-20 1991-12-26 Aktiebolaget Astra Dialkoxy-pyridinyl-benzimidazole derivatives, process for their preparation and their pharmaceutical use
SE9002206D0 (sv) 1990-06-20 1990-06-20 Haessle Ab New compounds
ES2048109B1 (es) * 1992-07-20 1994-12-16 Espanola Prod Quimicos Procedimiento de preparacion de nuevos derivados piperidicos del bencimidazol.
WO1995032957A1 (en) * 1994-05-27 1995-12-07 Astra Aktiebolag Novel ethoxycarbonyloxymethyl derivatives of substituted benzimidazoles
ES2192394T3 (es) * 1998-08-10 2003-10-01 Winston Pharmateuticals Llc Profarmacos de inhibidores de la bomba de protones.
US6093734A (en) * 1998-08-10 2000-07-25 Partnership Of Michael E. Garst, George Sachs, And Jai Moo Shin Prodrugs of proton pump inhibitors
US6852739B1 (en) 1999-02-26 2005-02-08 Nitromed Inc. Methods using proton pump inhibitors and nitric oxide donors
US6369087B1 (en) * 1999-08-26 2002-04-09 Robert R. Whittle Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
US20040039027A1 (en) * 2000-10-12 2004-02-26 Keiji Kamiyama Benzimidazole compounds, process for producing the same and use thereof
WO2003027098A1 (en) * 2001-09-25 2003-04-03 Takeda Chemical Industries, Ltd. Benzimidazole compound, process for producing the same, and use thereof
JPWO2003106429A1 (ja) * 2002-06-14 2005-10-13 武田薬品工業株式会社 プロドラッグおよびその製造法
KR100788778B1 (ko) * 2002-07-19 2007-12-27 윈스턴 파마슈티컬즈, 엘엘씨 벤즈이미다졸 유도체 및 이들의 프로톤 펌프 억제제의프로드럭으로서의 이용
EP1534278A4 (en) 2002-08-01 2006-09-06 Nitromed Inc NITROSED PROTONATE PUMP INHIBITORS, COMPOSITIONS AND USE METHOD
MY148805A (en) 2002-10-16 2013-05-31 Takeda Pharmaceutical Controlled release preparation
CA2529984C (en) * 2003-06-26 2012-09-25 Isa Odidi Oral multi-functional pharmaceutical capsule preparations of proton pump inhibitors
US20050075371A1 (en) * 2003-10-03 2005-04-07 Allergan, Inc. Methods and compositions for the oral administration of prodrugs of proton pump inhibitors
US20060241037A1 (en) * 2003-10-03 2006-10-26 Allergan Inc. Compositions comprising trefoil factor family peptides and/or mucoadhesives and proton pump ihhibitor prodrugs
WO2005082338A2 (en) * 2004-02-18 2005-09-09 Allergan, Inc. Prodrugs for the intravenous administration of proton pump inhibitors
US20070060621A1 (en) * 2004-02-18 2007-03-15 Hughes Patrick M Methods and compositions for the administration of prodrugs of proton pump inhibitors
EP1742630A4 (en) * 2004-04-16 2010-01-20 Santarus Inc COMBINATION OF INHIBITOR OF PROTON PUMP, BUFFER AND PROKINETIC AGENT
ES2327926T3 (es) 2004-04-28 2009-11-05 Hetero Drugs Limited Procedimiento de preparacion de compuestos de piridinilmetil-1h-benzimidazol en forma de enantiomeros simples o enantiomericamente enriquecidos.
DK1748998T3 (da) 2004-05-28 2010-05-10 Hetero Drugs Ltd Ny stereoselektiv syntese af benzimidazolsulfoxider
US8394409B2 (en) * 2004-07-01 2013-03-12 Intellipharmaceutics Corp. Controlled extended drug release technology
US10624858B2 (en) 2004-08-23 2020-04-21 Intellipharmaceutics Corp Controlled release composition using transition coating, and method of preparing same
US10064828B1 (en) 2005-12-23 2018-09-04 Intellipharmaceutics Corp. Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems
CN104825397A (zh) * 2006-04-03 2015-08-12 伊萨·奥迪迪 含有机溶胶涂层的受控释放递送物件
US10960077B2 (en) 2006-05-12 2021-03-30 Intellipharmaceutics Corp. Abuse and alcohol resistant drug composition
WO2008036201A1 (en) * 2006-09-19 2008-03-27 Alevium Pharmaceuticals, Inc. Prodrugs of proton pump inhibitors including the 1h-imidazo[4,5-b] pyridine moiety
EP2086543A2 (en) 2006-10-27 2009-08-12 The Curators of the University of Missouri Compositions comprising at least one acid labile proton pump inhibiting agents, optionally other pharmaceutically active agents and methods of using same
US20080194307A1 (en) * 2007-02-13 2008-08-14 Jeff Sanger Sports-based game of chance
CA2716367C (en) 2008-02-20 2015-05-26 The Curators Of The University Of Missouri Composition comprising a combination of omeprazole and lansoprazole, and a buffering agent, and methods of using same
WO2011084848A2 (en) 2010-01-07 2011-07-14 Alkermes, Inc. Prodrugs of heteraromatic compounds

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE418966B (sv) * 1974-02-18 1981-07-06 Haessle Ab Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan
US4045564A (en) * 1974-02-18 1977-08-30 Ab Hassle Benzimidazole derivatives useful as gastric acid secretion inhibitors
SE416649B (sv) * 1974-05-16 1981-01-26 Haessle Ab Forfarande for framstellning av foreningar som paverkar magsyrasekretionen
IN148930B (OSRAM) * 1977-09-19 1981-07-25 Hoffmann La Roche
SE7804231L (sv) * 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
US4359465A (en) * 1980-07-28 1982-11-16 The Upjohn Company Methods for treating gastrointestinal inflammation
CH644116A5 (de) * 1980-08-21 1984-07-13 Hoffmann La Roche Imidazolderivate.
SE8300736D0 (sv) * 1983-02-11 1983-02-11 Haessle Ab Novel pharmacologically active compounds
IL75400A (en) * 1984-06-16 1988-10-31 Byk Gulden Lomberg Chem Fab Dialkoxypyridine methyl(sulfinyl or sulfonyl)benzimidazoles,processes for the preparation thereof and pharmaceutical compositions containing the same
AU568441B2 (en) * 1984-09-24 1987-12-24 Upjohn Company, The 2-(pyridylalkenesulfinyl) benzimidazole derivatives
ZA856671B (en) * 1984-09-24 1986-04-30 Upjohn Co N-substituted derivatives of 2-(pyridylaklenesulfinyl)benzimidazoles as gastric antisecretory agents

Also Published As

Publication number Publication date
HUT43843A (en) 1987-12-28
ES2051696T3 (es) 1994-07-01
NO171365B (no) 1992-11-23
US5021433A (en) 1991-06-04
EP0221041A2 (en) 1987-05-06
KR870700620A (ko) 1987-12-30
PL262105A1 (en) 1988-08-18
FI91151B (fi) 1994-02-15
JPS63501151A (ja) 1988-04-28
IS3156A7 (is) 1987-04-30
ATE79619T1 (de) 1992-09-15
NO872686D0 (no) 1987-06-26
DE3686483D1 (de) 1992-09-24
IS1564B (is) 1994-12-13
EP0233284B1 (en) 1992-08-19
DK320587A (da) 1987-06-24
AU6542986A (en) 1987-05-19
EP0233284A1 (en) 1987-08-26
LTIP1681A (en) 1995-09-25
JPH0780874B2 (ja) 1995-08-30
CN86107595A (zh) 1987-07-08
FI872864L (fi) 1987-06-29
IE59167B1 (en) 1994-01-12
PL150240B1 (en) 1990-05-31
KR950009858B1 (ko) 1995-08-29
LV10270B (en) 1995-04-20
PT83647A (en) 1986-11-01
HU198474B (en) 1989-10-30
CS782686A2 (en) 1990-05-14
NO872686L (no) 1987-06-26
MY101791A (en) 1992-01-31
NO171365C (no) 1993-03-03
WO1987002668A1 (en) 1987-05-07
EP0221041A3 (en) 1987-10-28
IE862805L (en) 1987-04-29
EG17753A (en) 1991-12-30
JPH0826014B2 (ja) 1996-03-13
ZA867716B (en) 1987-05-27
PH25319A (OSRAM) 1991-04-30
SE8505112D0 (sv) 1985-10-29
DD252375A5 (de) 1987-12-16
CS272767B2 (en) 1991-02-12
FI91151C (sv) 1994-05-25
LV10270A (lv) 1994-10-20
GR3006177T3 (OSRAM) 1993-06-21
CN1022487C (zh) 1993-10-20
DK320587D0 (da) 1987-06-24
NZ218028A (en) 1990-02-26
JPH07188216A (ja) 1995-07-25
AU598491B2 (en) 1990-06-28
FI872864A0 (fi) 1987-06-29
JO1502B1 (en) 1989-01-25
PT83647B (pt) 1989-05-31
DE3686483T2 (de) 1993-02-04

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Legal Events

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