MY101791A - New benzimidazole derivatives - Google Patents

New benzimidazole derivatives

Info

Publication number
MY101791A
MY101791A MYPI86000038A MYPI19860038A MY101791A MY 101791 A MY101791 A MY 101791A MY PI86000038 A MYPI86000038 A MY PI86000038A MY PI19860038 A MYPI19860038 A MY PI19860038A MY 101791 A MY101791 A MY 101791A
Authority
MY
Malaysia
Prior art keywords
benzimidazole derivatives
new benzimidazole
compounds
new
formula
Prior art date
Application number
MYPI86000038A
Other languages
English (en)
Inventor
Lennart Lindberg Per
Borje Alminger Tomas
Elisabeth Sunden Gunnel
Sigurd Larsson Hakan
Original Assignee
Ab Hassle
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ab Hassle filed Critical Ab Hassle
Publication of MY101791A publication Critical patent/MY101791A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Indole Compounds (AREA)
MYPI86000038A 1985-10-29 1986-10-27 New benzimidazole derivatives MY101791A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8505112A SE8505112D0 (sv) 1985-10-29 1985-10-29 Novel pharmacological compounds

Publications (1)

Publication Number Publication Date
MY101791A true MY101791A (en) 1992-01-31

Family

ID=20361960

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI86000038A MY101791A (en) 1985-10-29 1986-10-27 New benzimidazole derivatives

Country Status (31)

Country Link
US (1) US5021433A (OSRAM)
EP (2) EP0221041A3 (OSRAM)
JP (2) JPH0780874B2 (OSRAM)
KR (1) KR950009858B1 (OSRAM)
CN (1) CN1022487C (OSRAM)
AT (1) ATE79619T1 (OSRAM)
AU (1) AU598491B2 (OSRAM)
CS (1) CS272767B2 (OSRAM)
DD (1) DD252375A5 (OSRAM)
DE (1) DE3686483T2 (OSRAM)
DK (1) DK320587D0 (OSRAM)
EG (1) EG17753A (OSRAM)
ES (1) ES2051696T3 (OSRAM)
FI (1) FI91151C (OSRAM)
GR (1) GR3006177T3 (OSRAM)
HU (1) HU198474B (OSRAM)
IE (1) IE59167B1 (OSRAM)
IL (1) IL80437A0 (OSRAM)
IS (1) IS1564B (OSRAM)
JO (1) JO1502B1 (OSRAM)
LT (1) LTIP1681A (OSRAM)
LV (1) LV10270B (OSRAM)
MY (1) MY101791A (OSRAM)
NO (1) NO171365C (OSRAM)
NZ (1) NZ218028A (OSRAM)
PH (1) PH25319A (OSRAM)
PL (1) PL150240B1 (OSRAM)
PT (1) PT83647B (OSRAM)
SE (1) SE8505112D0 (OSRAM)
WO (1) WO1987002668A1 (OSRAM)
ZA (1) ZA867716B (OSRAM)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ234564A (en) * 1986-11-21 1991-04-26 Haessle Ab 1-substituted benzimidazoles and pharmaceutical compositions
EP0436025A4 (en) * 1988-09-20 1991-09-11 Hisamitsu Pharmaceutical Co. Inc. Novel dibenz b,e)oxepin derivatives
EG19302A (en) * 1988-12-22 1994-11-30 Haessle Ab Compound with gastric acid inhibitory effect and process for its preparation
SE8804629D0 (sv) * 1988-12-22 1988-12-22 Ab Haessle New therapeutically active compounds
US4965269A (en) * 1989-12-20 1990-10-23 Ab Hassle Therapeutically active chloro substituted benzimidazoles
US5274099A (en) * 1989-12-20 1993-12-28 Aktiebolaget Hassle Therapeutically active fluoro substituted benzimidazoles
US5049674A (en) * 1989-12-20 1991-09-17 Aktiebolaget Hassle Therapeutically active fluoro substituted benzimidazoles
SE9002206D0 (sv) 1990-06-20 1990-06-20 Haessle Ab New compounds
AU649456B2 (en) * 1990-06-20 1994-05-26 Astra Aktiebolag Dialkoxy-pyridinyl-benzimidazole derivatives, process for their preparation and their pharmaceutical use
ES2048109B1 (es) * 1992-07-20 1994-12-16 Espanola Prod Quimicos Procedimiento de preparacion de nuevos derivados piperidicos del bencimidazol.
WO1995032957A1 (en) * 1994-05-27 1995-12-07 Astra Aktiebolag Novel ethoxycarbonyloxymethyl derivatives of substituted benzimidazoles
US6093734A (en) * 1998-08-10 2000-07-25 Partnership Of Michael E. Garst, George Sachs, And Jai Moo Shin Prodrugs of proton pump inhibitors
HRP20010106A2 (en) 1998-08-10 2002-02-28 Partnership Of Michael E Garst Prodrugs of proton pump inhibitors
US6852739B1 (en) 1999-02-26 2005-02-08 Nitromed Inc. Methods using proton pump inhibitors and nitric oxide donors
US6369087B1 (en) * 1999-08-26 2002-04-09 Robert R. Whittle Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
WO2002030920A1 (en) * 2000-10-12 2002-04-18 Takeda Chemical Industries, Ltd. Benzimidazole compounds, process for producing the same and use thereof
EP1437352A4 (en) * 2001-09-25 2004-12-08 Takeda Chemical Industries Ltd BENZIMIDAZOLE COMPOUND, METHOD FOR THE PRODUCTION AND USE THEREOF
US7410981B2 (en) * 2002-06-14 2008-08-12 Takeda Pharmaceutical Company Limited Prodrugs of imidazole derivatives, for use as proton pump inhibitors in the treatment of e.g. peptic ulcers
PL375255A1 (en) * 2002-07-19 2005-11-28 Winston Pharmaceuticals Llc Prodrugs of proton pump inhibitors
WO2004012659A2 (en) 2002-08-01 2004-02-12 Nitromed, Inc. Nitrosated proton pump inhibitors, compositions and methods of use
MY148805A (en) 2002-10-16 2013-05-31 Takeda Pharmaceutical Controlled release preparation
US8802139B2 (en) * 2003-06-26 2014-08-12 Intellipharmaceutics Corp. Proton pump-inhibitor-containing capsules which comprise subunits differently structured for a delayed release of the active ingredient
WO2005039640A1 (en) * 2003-10-03 2005-05-06 Allergan Inc. Compositions comprising trefoil factor family peptides and/or mucoadhesives and proton pump inhibitor prodrugs
US20050075371A1 (en) * 2003-10-03 2005-04-07 Allergan, Inc. Methods and compositions for the oral administration of prodrugs of proton pump inhibitors
JP2007523164A (ja) * 2004-02-18 2007-08-16 アラーガン、インコーポレイテッド プロトンポンプインヒビターに関連する化合物の静脈内投与のための方法および組成物
CA2556756A1 (en) * 2004-02-18 2005-09-09 Allergan, Inc. Compositions comprising prodrugs of proton pump inhibitors
WO2005117870A2 (en) * 2004-04-16 2005-12-15 Santarus, Inc. Combination of proton pump inhibitor, buffering agent, and prokinetic agent
ATE437869T1 (de) * 2004-04-28 2009-08-15 Hetero Drugs Ltd Verfahren zur herstellung von pyridinylmethyl-1h- benzimidazolverbindungen in enantiomerenangereicherter form oder als einzelne enantiomere
US7365206B2 (en) 2004-05-28 2008-04-29 Hetero Drugs Limited Stereoselective synthesis of benzimidazole sulfoxides
US8394409B2 (en) * 2004-07-01 2013-03-12 Intellipharmaceutics Corp. Controlled extended drug release technology
US10624858B2 (en) 2004-08-23 2020-04-21 Intellipharmaceutics Corp Controlled release composition using transition coating, and method of preparing same
US10064828B1 (en) 2005-12-23 2018-09-04 Intellipharmaceutics Corp. Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems
US9561188B2 (en) * 2006-04-03 2017-02-07 Intellipharmaceutics Corporation Controlled release delivery device comprising an organosol coat
US10960077B2 (en) 2006-05-12 2021-03-30 Intellipharmaceutics Corp. Abuse and alcohol resistant drug composition
WO2008036201A1 (en) * 2006-09-19 2008-03-27 Alevium Pharmaceuticals, Inc. Prodrugs of proton pump inhibitors including the 1h-imidazo[4,5-b] pyridine moiety
WO2008057802A2 (en) 2006-10-27 2008-05-15 The Curators Of The University Of Missouri Compositions comprising at least one acid labile proton pump inhibiting agents, optionally other pharmaceutically active agents and methods of using same
US20080194307A1 (en) * 2007-02-13 2008-08-14 Jeff Sanger Sports-based game of chance
US8247440B2 (en) 2008-02-20 2012-08-21 Curators Of The University Of Missouri Composition comprising omeprazole, lansoprazole and at least one buffering agent
AU2010339691B2 (en) * 2010-01-07 2015-04-02 Alkermes Pharma Ireland Limited Prodrugs of heteraromatic compounds

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4045564A (en) * 1974-02-18 1977-08-30 Ab Hassle Benzimidazole derivatives useful as gastric acid secretion inhibitors
SE418966B (sv) * 1974-02-18 1981-07-06 Haessle Ab Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan
SE416649B (sv) * 1974-05-16 1981-01-26 Haessle Ab Forfarande for framstellning av foreningar som paverkar magsyrasekretionen
IN148930B (OSRAM) * 1977-09-19 1981-07-25 Hoffmann La Roche
SE7804231L (sv) * 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
US4359465A (en) * 1980-07-28 1982-11-16 The Upjohn Company Methods for treating gastrointestinal inflammation
CH644116A5 (de) * 1980-08-21 1984-07-13 Hoffmann La Roche Imidazolderivate.
SE8300736D0 (sv) * 1983-02-11 1983-02-11 Haessle Ab Novel pharmacologically active compounds
IL75400A (en) * 1984-06-16 1988-10-31 Byk Gulden Lomberg Chem Fab Dialkoxypyridine methyl(sulfinyl or sulfonyl)benzimidazoles,processes for the preparation thereof and pharmaceutical compositions containing the same
AU568441B2 (en) * 1984-09-24 1987-12-24 Upjohn Company, The 2-(pyridylalkenesulfinyl) benzimidazole derivatives
ZA856671B (en) * 1984-09-24 1986-04-30 Upjohn Co N-substituted derivatives of 2-(pyridylaklenesulfinyl)benzimidazoles as gastric antisecretory agents

Also Published As

Publication number Publication date
DK320587A (da) 1987-06-24
NO171365C (no) 1993-03-03
AU598491B2 (en) 1990-06-28
CN86107595A (zh) 1987-07-08
LV10270A (lv) 1994-10-20
CS782686A2 (en) 1990-05-14
PH25319A (OSRAM) 1991-04-30
ES2051696T3 (es) 1994-07-01
PL150240B1 (en) 1990-05-31
FI872864L (fi) 1987-06-29
NO872686D0 (no) 1987-06-26
PL262105A1 (en) 1988-08-18
FI872864A0 (fi) 1987-06-29
FI91151C (sv) 1994-05-25
IE59167B1 (en) 1994-01-12
EP0221041A3 (en) 1987-10-28
EP0221041A2 (en) 1987-05-06
JPH07188216A (ja) 1995-07-25
LTIP1681A (en) 1995-09-25
HU198474B (en) 1989-10-30
NO171365B (no) 1992-11-23
WO1987002668A1 (en) 1987-05-07
IE862805L (en) 1987-04-29
CN1022487C (zh) 1993-10-20
LV10270B (en) 1995-04-20
CS272767B2 (en) 1991-02-12
JO1502B1 (en) 1989-01-25
FI91151B (fi) 1994-02-15
KR950009858B1 (ko) 1995-08-29
ATE79619T1 (de) 1992-09-15
PT83647A (en) 1986-11-01
JPH0826014B2 (ja) 1996-03-13
IS1564B (is) 1994-12-13
US5021433A (en) 1991-06-04
EG17753A (en) 1991-12-30
EP0233284A1 (en) 1987-08-26
AU6542986A (en) 1987-05-19
PT83647B (pt) 1989-05-31
JPH0780874B2 (ja) 1995-08-30
KR870700620A (ko) 1987-12-30
HUT43843A (en) 1987-12-28
SE8505112D0 (sv) 1985-10-29
DE3686483T2 (de) 1993-02-04
NZ218028A (en) 1990-02-26
IL80437A0 (en) 1987-01-30
EP0233284B1 (en) 1992-08-19
DK320587D0 (da) 1987-06-24
JPS63501151A (ja) 1988-04-28
ZA867716B (en) 1987-05-27
DD252375A5 (de) 1987-12-16
IS3156A7 (is) 1987-04-30
NO872686L (no) 1987-06-26
DE3686483D1 (de) 1992-09-24
GR3006177T3 (OSRAM) 1993-06-21

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