ATE437869T1 - Verfahren zur herstellung von pyridinylmethyl-1h- benzimidazolverbindungen in enantiomerenangereicherter form oder als einzelne enantiomere - Google Patents
Verfahren zur herstellung von pyridinylmethyl-1h- benzimidazolverbindungen in enantiomerenangereicherter form oder als einzelne enantiomereInfo
- Publication number
- ATE437869T1 ATE437869T1 AT04729974T AT04729974T ATE437869T1 AT E437869 T1 ATE437869 T1 AT E437869T1 AT 04729974 T AT04729974 T AT 04729974T AT 04729974 T AT04729974 T AT 04729974T AT E437869 T1 ATE437869 T1 AT E437869T1
- Authority
- AT
- Austria
- Prior art keywords
- enantiomer
- pyridinylmethyl
- production
- enriched form
- individual enantiomers
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- QQTZYHKWYUCCFC-UHFFFAOYSA-N 1-(pyridin-2-ylmethyl)benzimidazole Chemical class C1=NC2=CC=CC=C2N1CC1=CC=CC=N1 QQTZYHKWYUCCFC-UHFFFAOYSA-N 0.000 title 1
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical compound C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 title 1
- SUBDBMMJDZJVOS-UHFFFAOYSA-N 5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole Chemical compound N=1C2=CC(OC)=CC=C2NC=1S(=O)CC1=NC=C(C)C(OC)=C1C SUBDBMMJDZJVOS-UHFFFAOYSA-N 0.000 abstract 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 abstract 1
- 238000010511 deprotection reaction Methods 0.000 abstract 1
- SUBDBMMJDZJVOS-DEOSSOPVSA-N esomeprazole Chemical compound C([S@](=O)C1=NC2=CC=C(C=C2N1)OC)C1=NC=C(C)C(OC)=C1C SUBDBMMJDZJVOS-DEOSSOPVSA-N 0.000 abstract 1
- 229960004770 esomeprazole Drugs 0.000 abstract 1
- 238000001640 fractional crystallisation Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229960000381 omeprazole Drugs 0.000 abstract 1
- 150000003462 sulfoxides Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/IN2004/000118 WO2005105786A1 (en) | 2004-04-28 | 2004-04-28 | A process for preparing pyridinylmethyl-1h- benzimidazole compounds in enantiomerically enriched form or as single enantiomers |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE437869T1 true ATE437869T1 (de) | 2009-08-15 |
Family
ID=35241611
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04729974T ATE437869T1 (de) | 2004-04-28 | 2004-04-28 | Verfahren zur herstellung von pyridinylmethyl-1h- benzimidazolverbindungen in enantiomerenangereicherter form oder als einzelne enantiomere |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US7176319B2 (de) |
| EP (1) | EP1740571B1 (de) |
| AT (1) | ATE437869T1 (de) |
| DE (1) | DE602004022337D1 (de) |
| DK (1) | DK1740571T3 (de) |
| ES (1) | ES2327926T3 (de) |
| PT (1) | PT1740571E (de) |
| WO (1) | WO2005105786A1 (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2510849A1 (en) * | 2002-12-19 | 2004-07-08 | Teva Pharmaceutical Industries Ltd | Solid states of pantoprazole sodium, processes for preparing them and processes for preparing known pantoprazole sodium hydrates |
| MXPA05013316A (es) * | 2003-06-10 | 2006-03-17 | Teva Pharma | Proceso para preparar bencimidazoles 2[-(piridinil)metil]sulfinil-sustituidos y derivados clorados novedosos de pantoprazol. |
| DK1748998T3 (da) * | 2004-05-28 | 2010-05-10 | Hetero Drugs Ltd | Ny stereoselektiv syntese af benzimidazolsulfoxider |
| US7553857B2 (en) * | 2005-12-23 | 2009-06-30 | Lek Pharmaceuticals D.D. | S-omeprazole magnesium |
| NZ579136A (en) | 2007-02-21 | 2012-05-25 | Cipla Ltd | Process for the preparation of esomeprazole magnesium dihydrate |
| FR2920428B1 (fr) * | 2007-08-29 | 2012-06-15 | Univ Rouen | Procede de dedoublement de sels de l'omeprazole |
| ATE533758T1 (de) | 2007-09-25 | 2011-12-15 | Hetero Drugs Ltd | Verfahren zur herstellung von enantiomerenreinem esomeprazol |
| EP2195309A4 (de) * | 2007-10-08 | 2013-04-24 | Hetero Drugs Ltd | Polymorphe von esomeprazolsalzen |
| EP2143722A1 (de) | 2008-07-09 | 2010-01-13 | Lek Pharmaceuticals D.D. | Verfahren zur Herstellung von Esomeprazol-Natrium von hoher chemischer Reinheit und neue Formen von Esomeprazol-Natrium |
| US20100113527A1 (en) * | 2008-09-30 | 2010-05-06 | Teva Pharmaceutical Industries Ltd. | Crystalline forms of dexlansoprazole |
| US8354541B2 (en) | 2008-11-18 | 2013-01-15 | Hetero Research Foundation | Optical purification of esomeprazole |
| WO2011058569A1 (en) | 2009-11-12 | 2011-05-19 | Hetero Research Foundation | Process for the resolution of omeprazole |
| CN104011180B (zh) | 2011-09-27 | 2017-09-05 | 沙特阿拉伯石油公司 | 氧化脱硫反应产物的选择性液‑液萃取 |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE7804231L (sv) | 1978-04-14 | 1979-10-15 | Haessle Ab | Magsyrasekretionsmedel |
| US5984789A (en) * | 1983-11-15 | 1999-11-16 | Luk Lamellen Und Kupplungsbau Gmbh | Assembly for taking up and compensating for torque induced shocks |
| SE8505112D0 (sv) | 1985-10-29 | 1985-10-29 | Haessle Ab | Novel pharmacological compounds |
| DE4035455A1 (de) | 1990-11-08 | 1992-05-14 | Byk Gulden Lomberg Chem Fab | Enantiomerentrennung |
| SE9301830D0 (sv) | 1993-05-28 | 1993-05-28 | Ab Astra | New compounds |
| SE504459C2 (sv) * | 1994-07-15 | 1997-02-17 | Astra Ab | Förfarande för framställning av substituerade sulfoxider |
| US7036725B2 (en) * | 1995-06-06 | 2006-05-02 | Smart Media Of Delaware, Inc. | Shopping cart handle with built-in console for the input and display of consumer product information |
| US6422462B1 (en) * | 1998-03-30 | 2002-07-23 | Morris E. Cohen | Apparatus and methods for improved credit cards and credit card transactions |
| CN100396675C (zh) * | 1998-08-10 | 2008-06-25 | 加利福尼亚州大学董事会 | 质子泵抑制剂的前药 |
| US6145741A (en) * | 1999-04-27 | 2000-11-14 | Wisdom; Juanita J. | Universal pre-paid gasoline and travel card |
| WO2001031555A1 (en) * | 1999-10-28 | 2001-05-03 | Gould David B | Prepaid cash equivalent card and system |
| US7099568B2 (en) * | 2000-03-21 | 2006-08-29 | Sony Corporation | Information playback apparatus and electronic pop advertising apparatus |
| AU2002248227C1 (en) * | 2000-12-19 | 2012-07-19 | Paltronics, Inc. | Video table game apparatus, system, and method of use |
| US7103573B2 (en) * | 2001-04-02 | 2006-09-05 | Privilegeone Networks, Llc | User rewards program and associated communications system |
| US20020153424A1 (en) * | 2001-04-19 | 2002-10-24 | Chuan Li | Method and apparatus of secure credit card transaction |
| US20020178063A1 (en) * | 2001-05-25 | 2002-11-28 | Kelly Gravelle | Community concept for payment using RF ID transponders |
| US20040248941A1 (en) | 2001-09-25 | 2004-12-09 | Keiji Kamiyama | Benzimidazone compound, process for producing the same, and use thereof |
| US20030066073A1 (en) * | 2001-09-28 | 2003-04-03 | Rebh Richard G. | Methods and systems of interactive advertising |
| US20040044574A1 (en) * | 2002-06-04 | 2004-03-04 | Kordex, Inc. | Apparatus for displaying local advertising to a display screen |
| AU2003242388A1 (en) | 2002-06-14 | 2003-12-31 | Takeda Pharmaceutical Company Limited | Prodrug and process for producing the same |
| EP1515963B1 (de) | 2002-06-27 | 2007-02-14 | Dr. Reddy's Laboratories Ltd. | Verfahren zur herstellung optisch reiner oder optisch angereicherter sulfoxidverbindungen einschliesslich amorphen esomeprazols und dessen salze |
| ES2263028T3 (es) | 2002-07-19 | 2006-12-01 | Winston Pharmaceuticals Llc | Derivados de bencimidazol y su uso como profarmacos de inhibidores de bomba de proton. |
| AU2003248880A1 (en) * | 2002-11-26 | 2004-06-18 | The Advertizing Firm, Inc. | Method and system of advertising |
| US7593867B2 (en) * | 2004-01-12 | 2009-09-22 | The Coca-Cola Company | Interactive networked product container |
| US7510123B2 (en) * | 2004-11-18 | 2009-03-31 | Goliath Solutions, Llc | RF contact signal detector |
| US7055740B1 (en) * | 2004-12-06 | 2006-06-06 | Target Brands, Inc. | Stored-value card adapted to be read by an electronic device |
| US7290714B2 (en) * | 2005-01-18 | 2007-11-06 | Target Brands, Inc. | Stored-value card with light |
-
2004
- 2004-04-28 AT AT04729974T patent/ATE437869T1/de active
- 2004-04-28 DK DK04729974T patent/DK1740571T3/da active
- 2004-04-28 DE DE602004022337T patent/DE602004022337D1/de not_active Expired - Lifetime
- 2004-04-28 PT PT04729974T patent/PT1740571E/pt unknown
- 2004-04-28 US US10/503,830 patent/US7176319B2/en not_active Expired - Lifetime
- 2004-04-28 EP EP04729974A patent/EP1740571B1/de not_active Revoked
- 2004-04-28 WO PCT/IN2004/000118 patent/WO2005105786A1/en not_active Ceased
- 2004-04-28 ES ES04729974T patent/ES2327926T3/es not_active Expired - Lifetime
-
2007
- 2007-01-08 US US11/620,843 patent/US7435826B2/en not_active Expired - Fee Related
- 2007-01-08 US US11/620,830 patent/US7928240B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DK1740571T3 (da) | 2009-11-02 |
| US20070129405A1 (en) | 2007-06-07 |
| PT1740571E (pt) | 2009-09-02 |
| US20060089386A1 (en) | 2006-04-27 |
| US20070129406A1 (en) | 2007-06-07 |
| WO2005105786A1 (en) | 2005-11-10 |
| DE602004022337D1 (de) | 2009-09-10 |
| US7435826B2 (en) | 2008-10-14 |
| US7176319B2 (en) | 2007-02-13 |
| US7928240B2 (en) | 2011-04-19 |
| EP1740571A1 (de) | 2007-01-10 |
| EP1740571B1 (de) | 2009-07-29 |
| ES2327926T3 (es) | 2009-11-05 |
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Legal Events
| Date | Code | Title | Description |
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| UEP | Publication of translation of european patent specification |
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