ZA861565B - Controlled-release multiple units pharmaceutical formulation - Google Patents

Controlled-release multiple units pharmaceutical formulation

Info

Publication number
ZA861565B
ZA861565B ZA861565A ZA861565A ZA861565B ZA 861565 B ZA861565 B ZA 861565B ZA 861565 A ZA861565 A ZA 861565A ZA 861565 A ZA861565 A ZA 861565A ZA 861565 B ZA861565 B ZA 861565B
Authority
ZA
South Africa
Prior art keywords
controlled
pharmaceutical formulation
multiple units
release multiple
units pharmaceutical
Prior art date
Application number
ZA861565A
Other languages
English (en)
Inventor
Muneo Fukui
Kouji Tomuro
Shigeru Masuyama
Atsushi Kajiyama
Tamio Hikosaka
Massayoshi Aruga
Yoshiaki Soeishi
Saburo Higuchi
Original Assignee
Yamanouchi Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=12739832&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA861565(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Yamanouchi Pharma Co Ltd filed Critical Yamanouchi Pharma Co Ltd
Publication of ZA861565B publication Critical patent/ZA861565B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA861565A 1985-03-08 1986-03-03 Controlled-release multiple units pharmaceutical formulation ZA861565B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP4618085 1985-03-08

Publications (1)

Publication Number Publication Date
ZA861565B true ZA861565B (en) 1986-10-29

Family

ID=12739832

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA861565A ZA861565B (en) 1985-03-08 1986-03-03 Controlled-release multiple units pharmaceutical formulation

Country Status (8)

Country Link
US (1) US4772475A (ko)
EP (2) EP0533297B1 (ko)
JP (1) JPH0772129B2 (ko)
KR (1) KR930007245B1 (ko)
CA (1) CA1264293A (ko)
DE (2) DE3650657D1 (ko)
ES (1) ES8800041A1 (ko)
ZA (1) ZA861565B (ko)

Families Citing this family (89)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4690487A (en) * 1983-11-14 1987-09-01 Allied Corporation Hermetically sealed fiber optic connector
NL8500724A (nl) * 1985-03-13 1986-10-01 Univ Groningen Inrichtingen voor geregelde afgifte van werkzame stoffen, alsmede werkwijze ter vervaardiging daarvan.
GB8618811D0 (en) * 1986-08-01 1986-09-10 Approved Prescription Services Sustained release ibuprofen formulation
US5129877A (en) * 1988-04-29 1992-07-14 University Of Georgia Research Foundation, Inc. Receptor-mediated delivery system
US5169642A (en) * 1988-06-24 1992-12-08 Abbott Laboratories Sustained-release drug dosage units
US5268182A (en) * 1988-06-24 1993-12-07 Abbott Laboratories Sustained-release drug dosage units of terazosin
US5028433A (en) * 1988-11-30 1991-07-02 Banyu Pharmaceutical Co., Ltd. Readily absorbable drug formulation of NB-818
US5258186A (en) * 1989-03-10 1993-11-02 Yamanouchi Pharmaceutical Co., Ltd. Drug release controlling coating material for long acting formulations
IE64061B1 (en) * 1989-09-04 1995-07-12 Yamanouchi Pharma Co Ltd External preparation containing amusulosin
CA2034171A1 (en) * 1990-01-22 1991-07-23 Gorm Wagner Method of treating erectile dysfunction
US5175003A (en) * 1990-04-06 1992-12-29 Biosytes Usa, Inc. Dual mechanism controlled release system for drug dosage forms
AU8050791A (en) * 1990-06-20 1992-01-07 Advanced Polymer Systems Inc. Compositions and methods for the controlled release of soluble active substances
US5102668A (en) * 1990-10-05 1992-04-07 Kingaform Technology, Inc. Sustained release pharmaceutical preparation using diffusion barriers whose permeabilities change in response to changing pH
US5968551A (en) 1991-12-24 1999-10-19 Purdue Pharma L.P. Orally administrable opioid formulations having extended duration of effect
US6602861B1 (en) * 1992-04-16 2003-08-05 Research Corporation Technologies, Inc. Acylated phospholipid drugs
US5376384A (en) * 1992-12-23 1994-12-27 Kinaform Technology, Inc. Delayed, sustained-release pharmaceutical preparation
IL109460A (en) 1993-05-10 1998-03-10 Euro Celtique Sa Controlled release formulation comprising tramadol
IL110014A (en) 1993-07-01 1999-11-30 Euro Celtique Sa Solid controlled-release oral dosage forms of opioid analgesics
US7740881B1 (en) 1993-07-01 2010-06-22 Purdue Pharma Lp Method of treating humans with opioid formulations having extended controlled release
US5879705A (en) * 1993-07-27 1999-03-09 Euro-Celtique S.A. Sustained release compositions of morphine and a method of preparing pharmaceutical compositions
US5891471A (en) 1993-11-23 1999-04-06 Euro-Celtique, S.A. Pharmaceutical multiparticulates
KR100354702B1 (ko) 1993-11-23 2002-12-28 유로-셀티크 소시에떼 아노뉨 약학조성물의제조방법및서방형조성물
US5843480A (en) 1994-03-14 1998-12-01 Euro-Celtique, S.A. Controlled release diamorphine formulation
GB9505032D0 (en) 1995-03-13 1995-05-03 Westminster Lab Ltd Improvements in or relating to organic compositions
GB9422154D0 (en) 1994-11-03 1994-12-21 Euro Celtique Sa Pharmaceutical compositions and method of producing the same
US5965161A (en) 1994-11-04 1999-10-12 Euro-Celtique, S.A. Extruded multi-particulates
GB9519363D0 (en) 1995-09-22 1995-11-22 Euro Celtique Sa Pharmaceutical formulation
US5773031A (en) * 1996-02-27 1998-06-30 L. Perrigo Company Acetaminophen sustained-release formulation
GB9710699D0 (en) * 1997-05-24 1997-07-16 Danbiosyst Uk Gastro-retentive controlled release system
SE9702338D0 (sv) * 1997-06-18 1997-06-18 Astra Ab An analytical method and industrial process including the same
TW536402B (en) 1998-06-26 2003-06-11 Yamanouchi Pharma Co Ltd Pharmaceutical composition for the therapy of voiding dysfunction
US6806294B2 (en) 1998-10-15 2004-10-19 Euro-Celtique S.A. Opioid analgesic
DE19918325A1 (de) 1999-04-22 2000-10-26 Euro Celtique Sa Verfahren zur Herstellung von Arzneiformen mit regulierter Wirkstofffreisetzung mittels Extrusion
ATE526950T1 (de) 1999-10-29 2011-10-15 Euro Celtique Sa Hydrocodon-formulierungen mit gesteuerter freisetzung
US10179130B2 (en) 1999-10-29 2019-01-15 Purdue Pharma L.P. Controlled release hydrocodone formulations
EP2263658A1 (en) 2000-10-30 2010-12-22 Euro-Celtique S.A. Controlled release hydrocodone formulations
WO2002036077A2 (en) * 2000-11-06 2002-05-10 Andrx Pharmaceuticals, Inc. Once a day antihistamine and decongestant formulation
US20110104214A1 (en) 2004-04-15 2011-05-05 Purdue Pharma L.P. Once-a-day oxycodone formulations
UA81224C2 (uk) 2001-05-02 2007-12-25 Euro Celtic S A Дозована форма оксикодону та її застосування
KR100530546B1 (ko) 2001-07-27 2005-11-23 아스텔라스세이야쿠 가부시키가이샤 구강내에서 신속하게 붕괴되는 정제용 서방성 미립자가함유된 조성물 및 그의 제조 방법
PT1443917E (pt) * 2001-11-07 2006-06-30 Synthon Bv Comprimidos de tamsulosina
IL163666A0 (en) 2002-02-22 2005-12-18 New River Pharmaceuticals Inc Active agent delivery systems and methods for protecting and administering active agents
DE60313603T2 (de) * 2002-04-24 2008-01-03 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pharmazeutische kombination zur behandlung von benigner prostatahyperplasie oder zur langzeitvorbeugung von akuter harnzurückhaltung
US7018658B2 (en) * 2002-11-14 2006-03-28 Synthon Bv Pharmaceutical pellets comprising tamsulosin
KR100592512B1 (ko) * 2002-11-22 2006-07-03 서울약품공업(주) 탐술로신 또는 약제학적으로 허용되는 이의 염을활성성분으로 하는 서방성 배뇨장애 치료제
US20040253309A1 (en) * 2003-01-27 2004-12-16 Yamanouchi Pharmaceutical Co., Ltd. Enteric sustained-release fine particles of tamsulosin and its salt and manufacturing method thereof
CA2515585A1 (en) * 2003-01-27 2004-08-12 Yoji Tanijiri Enteric sustained-release fine particles for tamsulosin or its salt and manufacturing method thereof
JP4614139B2 (ja) * 2003-08-12 2011-01-19 キョンドン ファーム カンパニー リミテッド 塩酸タムスロシン徐放性錠剤の製造方法、およびそれからなる塩酸タムスロシン徐放性錠剤
JP2005104914A (ja) * 2003-09-30 2005-04-21 Kyowa Yakuhin Kogyo Kk 塩基性薬剤含有製剤
KR100436701B1 (ko) * 2003-11-07 2004-06-22 주식회사 씨티씨바이오 염산 탐스로신 함유 방출 조절형 제제 및 그의 제조방법
US8128958B2 (en) * 2003-11-10 2012-03-06 Astellas Pharma Inc. Sustained release pharmaceutical composition
US8197846B2 (en) * 2003-11-10 2012-06-12 Astellas Pharma Inc. Sustained release pharmaceutical composition
US20050106253A1 (en) * 2003-11-13 2005-05-19 Platteeuw Johannes J. Pharmaceutical pellets comprising tamsulosin
SI21637A (sl) * 2003-12-23 2005-06-30 LEK farmacevtska dru�ba d.d. Farmacevtska oblika z nadzorovanim sproščanjem
KR100582350B1 (ko) * 2004-02-17 2006-05-22 한미약품 주식회사 탐수로신 염산염의 경구투여용 조성물 및 이의 서방성과립 제제
US20050186275A1 (en) * 2004-02-23 2005-08-25 Standard Chem. & Pharm. Co. Ltd. Sustained release tamsulosin formulations
KR100681660B1 (ko) 2004-03-17 2007-02-09 주식회사종근당 방출제어 펠릿의 약제학적 조성물
US7491263B2 (en) 2004-04-05 2009-02-17 Technology Innovation, Llc Storage assembly
DE502004004032D1 (de) * 2004-07-14 2007-07-19 Siegfried Generics Internat Lt Granulat zur kontrollierten Freisetzung von Tamsulosin, enthaltend Alginat
US7238839B2 (en) * 2004-10-07 2007-07-03 Divi's Laboratories Limited Process for the resolution of racemic (R,S) -5-(2-(2-(2- ethoxyphenoxy) ethylamino)Propyl)-2-methoxybenzene sulfonamide (tamsulosin), its novel R and S isomers and their salts and processes for their preparation
US20060128719A1 (en) * 2004-12-13 2006-06-15 Boehringer Ingelheim Pharmaceuticals, Inc. Use of alpha-adrenergic blockers for the treatment of dysmenorrhea
US20090208579A1 (en) * 2004-12-27 2009-08-20 Eisai R & D Management Co., Ltd. Matrix Type Sustained-Release Preparation Containing Basic Drug or Salt Thereof, and Method for Manufacturing the Same
AU2005320547B2 (en) 2004-12-27 2009-02-05 Eisai R & D Management Co., Ltd. Method for stabilizing anti-dementia drug
JP2006232696A (ja) * 2005-02-23 2006-09-07 Taisho Pharm Ind Ltd 徐放性製剤
AU2006241771B2 (en) * 2005-04-28 2010-09-09 Eisai R & D Management Co., Ltd. Composition containing anti-dementia drug
EP2026766A1 (en) * 2006-05-17 2009-02-25 Synthon B.V. Tablet composition with a prolonged release of tamsulosin
CA2671200A1 (en) * 2006-07-21 2008-01-24 Lab International Srl Hydrophilic abuse deterrent delivery system
US20080113030A1 (en) * 2006-11-09 2008-05-15 Ching-Fen Hsiao Sustained release tamsulosin formulations
US20090004284A1 (en) * 2007-06-26 2009-01-01 Watson Pharmaceuticals, Inc. Controlled release tamsulosin hydrochloride formulation
WO2009076664A1 (en) 2007-12-13 2009-06-18 Vanda Pharmaceuticals Inc. Method and composition for treating a serotonin receptor-mediated condition
ES2527515T3 (es) 2007-12-13 2015-01-26 Vanda Pharmaceuticals Inc. Método y composición para tratar una afección mediada por un adrenoceptor alfa
MX2008010233A (es) * 2008-03-10 2009-11-10 Eurodrug Lab B V Composicion de liberacion modificada, que comprende doxofilina.
US8529953B2 (en) * 2008-07-01 2013-09-10 Sawai Pharmaceutical Co., Ltd. Process for production of spherical microparticles comprising tamsulosin hydrochloride
US8465770B2 (en) * 2008-12-24 2013-06-18 Synthon Bv Low dose controlled release tablet
WO2012110092A1 (en) 2011-02-17 2012-08-23 Synthon Bv Tamsulosin derivatives
WO2013045352A1 (de) 2011-09-30 2013-04-04 Basf Se Verfahren zur herstellung von festen pigmenthaltigen filmüberzugsmitteln in form von granulaten auf basis von magensaftresistenten filmbildnern für pharmazeutische dosierungsformen
JPWO2014188842A1 (ja) * 2013-05-21 2017-02-23 日本碍子株式会社 圧電デバイスの製造方法，及び圧電自立基板
WO2014203137A2 (en) 2013-06-21 2014-12-24 Wockhardt Limited Pharmaceutical compositions of tamsulosin or salts thereof
BR102013020508B1 (pt) 2013-08-12 2021-01-12 Ems S/A. Forma de dosagem que compreende um inibidor de esteroide 5-alfa-redutase e um bloqueador alfa, processo para a preparaçãode uma forma de dosagem e uso da forma de dosagem
ES2555485T1 (es) 2014-05-26 2016-01-04 Galenicum Health S.L. Composiciones farmacéuticas que contienen un agente activo
CA2936741C (en) 2014-10-31 2018-11-06 Purdue Pharma Methods and compositions particularly for treatment of attention deficit disorder
CZ2015225A3 (cs) 2015-03-30 2016-10-12 Zentiva, K.S. Nový krok ve způsobu potahování pelet obsahujících Tamsulosin.HCI
KR101879133B1 (ko) 2017-07-11 2018-07-17 (주)동구바이오제약 비뇨기 질환 예방 또는 치료용 제제 및 이의 제조방법
EP3473244A1 (en) 2017-10-20 2019-04-24 Veru Inc. Controlled release oral tamsulosin hydrochloride
EP3473245A1 (en) 2017-10-20 2019-04-24 Veru Inc. Controlled release oral tamsulosin hydrochloride
KR101957694B1 (ko) 2018-05-28 2019-03-13 (주)동구바이오제약 비뇨기 질환 예방 또는 치료용 제제 및 이의 제조방법
JP7370125B2 (ja) * 2018-11-09 2023-10-27 日本化薬株式会社 エルロチニブを有効成分とする医薬錠剤
JP7370124B2 (ja) * 2018-11-09 2023-10-27 日本化薬株式会社 エルロチニブを有効成分とする医薬錠剤
US10722473B2 (en) 2018-11-19 2020-07-28 Purdue Pharma L.P. Methods and compositions particularly for treatment of attention deficit disorder

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB630439A (en) * 1945-09-11 1949-10-13 Ethan Allan Brown Improvements in or relating to pharmaceutical preparations
DE1467781A1 (de) * 1963-07-15 1968-12-05 Boehringer Sohn Ingelheim Verfahren zur Herstellung von Dragees mit verlaengerter Wirkstofffreigabe
DE1962016C3 (de) * 1969-12-11 1979-11-08 Uzina De Medicamente Bucuresti, Bukarest Verfahren zur Herstellung von Tabletten mit protrahierter Wirkung
CA952431A (en) * 1970-09-28 1974-08-06 Frank M. Bardani Controlled release medicament
FR2183546B1 (ko) * 1972-05-10 1975-06-20 Servier Lab
JPS50131867A (ko) * 1974-04-08 1975-10-18
US4495189A (en) * 1975-11-27 1985-01-22 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara R.T. Condensed pyrimidines
HU173438B (hu) * 1975-11-27 1979-05-28 Chinoin Gyogyszer Es Vegyeszet Sposob poluchenija novykh proizvodnykh 4-okso-1,6,7,8-/tetragidro-4h-pirido/1,2/pirimidina s zaderzhivajuhhejj vozgoranie aktivnot'ju i protivosvertivajuhhem effektom
JPS535112A (en) * 1976-03-08 1978-01-18 Santen Pharmaceutical Co Ltd New cysteine derivatives
JPS5332111A (en) * 1976-09-07 1978-03-27 Asahi Chem Ind Co Ltd Composition for tablet
DD137186A1 (de) * 1978-06-30 1979-08-22 Guenther Magister Verfahren zur herstellung von rieselfaehigen produkten aus zellulosepulver
JPS6011888B2 (ja) * 1978-10-11 1985-03-28 参天製薬株式会社 リウマチ疾患治療薬
JPS55153715A (en) * 1979-05-18 1980-11-29 Nikken Kagaku Kk Prolonged granule of theophylline
JPS56110665A (en) * 1980-02-08 1981-09-01 Yamanouchi Pharmaceut Co Ltd Sulfamoyl-substituted phenetylamine derivative and its preparation
JPS6056122B2 (ja) * 1980-05-21 1985-12-09 塩野義製薬株式会社 徐放性製剤
JPS574921A (en) * 1980-06-13 1982-01-11 Chugai Pharmaceut Co Ltd Remedy for cardiovascular disorder
EP0056189B1 (en) * 1980-12-26 1986-08-20 Ss Pharmaceutical Co., Ltd. 2,3-butanediol diester derivatives, process for producing the same, and an antiulcer drug containing the same
JPS58189114A (ja) * 1982-04-30 1983-11-04 Ss Pharmaceut Co Ltd 抗潰瘍剤
US4552765A (en) * 1982-05-14 1985-11-12 Santen Pharmaceutical Co., Ltd. Aletheine derivatives
US4489026A (en) * 1982-09-07 1984-12-18 The Upjohn Company Process for preparing solid unit dosage forms of ultra-low dose drugs
JPS59190913A (ja) * 1983-04-14 1984-10-29 Eisai Co Ltd ケノデオキシコ−ル酸含有顆粒剤
JPS6036410A (ja) * 1983-08-08 1985-02-25 Unitika Ltd 生分解性薬物供与体の製造方法
DE3686275T2 (de) * 1985-01-11 1993-03-18 Teijin Ltd Praeparate mit verzoegerter freisetzung.

Also Published As

Publication number Publication date
EP0533297B1 (en) 1997-11-19
ES552794A0 (es) 1987-10-16
DE3650657D1 (de) 1998-01-02
EP0533297A1 (en) 1993-03-24
DE3688532D1 (de) 1993-07-15
US4772475A (en) 1988-09-20
KR930007245B1 (ko) 1993-08-04
EP0194838A2 (en) 1986-09-17
EP0194838B1 (en) 1993-06-09
CA1264293A (en) 1990-01-09
JPH0772129B2 (ja) 1995-08-02
JPS629A (ja) 1987-01-06
DE3688532T2 (de) 1993-09-23
KR860006984A (ko) 1986-10-06
ES8800041A1 (es) 1987-10-16
EP0194838A3 (en) 1988-02-03

Similar Documents

Publication Publication Date Title
ZA861565B (en) Controlled-release multiple units pharmaceutical formulation
GR862727B (en) Pharmaceutical preparation
GB8723896D0 (en) Controlled-release formulation
GB2187953B (en) Pharmaceutical formulation
ZA8667B (en) Pharmaceutical preparation
GB8623389D0 (en) Pharmaceutical formulations
GB8711274D0 (en) Ketoprofen pharmaceutical formulation
GR861421B (en) Pharmaceutical tablet
GB2174004B (en) Pharmaceutical tablet preparations
ZA876048B (en) Pharmaceutical formulation
GB8712240D0 (en) Pharmaceutical formulation
GB8630419D0 (en) Pharmaceutical formulation
GB8603031D0 (en) Pharmaceutical formulations
GB8519741D0 (en) Pharmaceutical formulation
GB8524811D0 (en) Pharmaceutical formulation
GB8502917D0 (en) Pharmaceutical formulation
GB8530794D0 (en) Pharmaceutical formulation
GB8402574D0 (en) Pharmaceutical formulation
GB8524653D0 (en) Pharmaceutical formulations
GB8521863D0 (en) Pharmaceutical formulations
AU93541S (en) Pharmaceutical tablet
AU93542S (en) Pharmaceutical tablet
GB8522761D0 (en) Pharmaceutical preparation
GB8624269D0 (en) Pharmaceutical formulation
GB8630904D0 (en) Pharmaceutical formulation