ZA844527B - Substituted phenylalkyl(piperazinyl or homopiperazinyl propyl-(ureas or thioureas) - Google Patents

Substituted phenylalkyl(piperazinyl or homopiperazinyl propyl-(ureas or thioureas)

Info

Publication number
ZA844527B
ZA844527B ZA844527A ZA844527A ZA844527B ZA 844527 B ZA844527 B ZA 844527B ZA 844527 A ZA844527 A ZA 844527A ZA 844527 A ZA844527 A ZA 844527A ZA 844527 B ZA844527 B ZA 844527B
Authority
ZA
South Africa
Prior art keywords
homopiperazinyl
thioureas
ureas
piperazinyl
propyl
Prior art date
Application number
ZA844527A
Other languages
English (en)
Inventor
John Peter Devlin
Karl Douglas Hargrave
Edward Leon Barsumian
Genus John Possanza
Original Assignee
Boehringer Ingelheim Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Ltd filed Critical Boehringer Ingelheim Ltd
Publication of ZA844527B publication Critical patent/ZA844527B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/08—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 not condensed with other rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA844527A 1983-06-16 1984-06-15 Substituted phenylalkyl(piperazinyl or homopiperazinyl propyl-(ureas or thioureas) ZA844527B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US50483783A 1983-06-16 1983-06-16

Publications (1)

Publication Number Publication Date
ZA844527B true ZA844527B (en) 1986-02-26

Family

ID=24007953

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA844527A ZA844527B (en) 1983-06-16 1984-06-15 Substituted phenylalkyl(piperazinyl or homopiperazinyl propyl-(ureas or thioureas)

Country Status (25)

Country Link
EP (1) EP0129207B1 (pl)
JP (1) JPS6075469A (pl)
KR (1) KR890000175B1 (pl)
AR (1) AR242377A1 (pl)
AT (1) ATE33023T1 (pl)
AU (1) AU565041B2 (pl)
CA (1) CA1219260A (pl)
CS (1) CS244821B2 (pl)
DD (1) DD223710A5 (pl)
DE (1) DE3469896D1 (pl)
DK (1) DK160554C (pl)
ES (3) ES533448A0 (pl)
FI (1) FI76327C (pl)
GR (1) GR82367B (pl)
HU (1) HU192409B (pl)
IE (1) IE59034B1 (pl)
IL (1) IL72123A (pl)
NO (1) NO161618C (pl)
NZ (1) NZ208535A (pl)
PH (1) PH24059A (pl)
PL (2) PL146314B1 (pl)
PT (1) PT78729B (pl)
SU (2) SU1542415A3 (pl)
YU (2) YU104584A (pl)
ZA (1) ZA844527B (pl)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4661481A (en) * 1983-06-16 1987-04-28 Boehringer Ingelheim Pharmaceuticals, Inc Substituted phenylalkylhomopiperazinylpropyl(ureas or thioureas) useful for treatment of immulogical, inflammatory and allergic disorders
FR2601366B1 (fr) * 1986-07-10 1988-11-25 Andre Buzas Derives de la benzhydryloxyethyl-piperazine, procedes d'obtention et de compositions pharmaceutiques les contenant.
JP2722250B2 (ja) * 1989-05-30 1998-03-04 興和株式会社 新規なジアミン化合物及びこれを含有する脳機能障害改善剤
JPH0525145A (ja) * 1991-07-15 1993-02-02 Mochida Pharmaceut Co Ltd アレルギー性疾患治療剤
JP3719612B2 (ja) * 1993-06-14 2005-11-24 塩野義製薬株式会社 ヘテロ環を含有する尿素誘導体
ITRM20060090A1 (it) * 2006-02-22 2007-08-23 Sigma Tau Ind Farmaceuti Nuovi composti inibitori cpt a livello del snc come farmaci antidiabetici e o antiobesita
TW201446748A (zh) 2007-08-22 2014-12-16 Astrazeneca Ab 環丙基醯胺衍生物
TW201039825A (en) * 2009-02-20 2010-11-16 Astrazeneca Ab Cyclopropyl amide derivatives 983
EP2536702A4 (en) 2010-02-18 2013-07-10 Astrazeneca Ab NEW CRYSTALLINE FORM OF A CYCLOPROPYLBENZAMIDE DERIVATIVE
EP3484880B1 (en) 2016-07-13 2020-09-02 Leo Pharma A/S Heteroaromatic modulators of the retinoid-related orphan receptor gamma

Also Published As

Publication number Publication date
PH24059A (en) 1990-03-05
FI76327C (fi) 1988-10-10
ES537661A0 (es) 1985-11-01
PL252851A1 (en) 1986-07-01
NO161618C (no) 1989-09-06
PT78729B (en) 1986-10-21
ES8506651A1 (es) 1985-08-01
DD223710A5 (de) 1985-06-19
FI842408A0 (fi) 1984-06-14
IL72123A0 (en) 1984-10-31
DK294084D0 (da) 1984-06-15
GR82367B (pl) 1984-12-13
CA1219260A (en) 1987-03-17
JPS6075469A (ja) 1985-04-27
YU150186A (en) 1987-06-30
AU2940484A (en) 1984-12-20
EP0129207A3 (en) 1985-07-31
DK160554B (da) 1991-03-25
EP0129207B1 (en) 1988-03-16
NO842417L (no) 1984-12-17
PL248207A1 (en) 1985-08-13
SU1542415A3 (ru) 1990-02-07
PL146314B1 (en) 1989-01-31
NZ208535A (en) 1987-02-20
AU565041B2 (en) 1987-09-03
IE59034B1 (en) 1993-12-15
FI842408A (fi) 1984-12-17
IE841499L (en) 1984-12-16
ES537662A0 (es) 1985-09-16
ES8601928A1 (es) 1985-11-01
IL72123A (en) 1987-09-16
KR890000175B1 (ko) 1989-03-09
DK294084A (da) 1984-12-17
JPH0469147B2 (pl) 1992-11-05
ES533448A0 (es) 1985-08-01
DK160554C (da) 1991-09-09
KR850000422A (ko) 1985-02-27
SU1387877A3 (ru) 1988-04-07
ES8600255A1 (es) 1985-09-16
YU104584A (en) 1986-12-31
DE3469896D1 (en) 1988-04-21
FI76327B (fi) 1988-06-30
EP0129207A2 (en) 1984-12-27
CS244821B2 (en) 1986-08-14
HUT34464A (en) 1985-03-28
NO161618B (no) 1989-05-29
PT78729A (en) 1984-07-01
PL147413B1 (en) 1989-05-31
HU192409B (en) 1987-06-29
ATE33023T1 (de) 1988-04-15
AR242377A1 (es) 1993-03-31

Similar Documents

Publication Publication Date Title
IL72342A0 (en) N-alkoxyaminosulfonylureas and n-alkylsulfonylaminosulfonylureas and(pyrimidino)(or triazino)thiazinothiatriazine dioxides as precursors
CY1436A (en) N-phenylsulfonyl-n-pyrimidinyl and-triazinyl ureas
IL63094A0 (en) Substituted ureas and thioureas
GR80603B (en) Arrangement for the lifting of postlids
ZA844527B (en) Substituted phenylalkyl(piperazinyl or homopiperazinyl propyl-(ureas or thioureas)
DE3467774D1 (en) Molybdenum board and process of manufacturing the same
GB8427976D0 (en) Coatings
GB8415125D0 (en) (3-alkyl-5-isothiazolyl)ureas
GB2149394B (en) Ureas
GB8305735D0 (en) Ergolinyl ureas
AU561832B2 (en) 1-(alkyl-phenoxyaryl)-3-benzoyl ureas
DE3472101D1 (en) Carbamate compounds, and their production and use
AU560505B2 (en) 1-phenyl-3-benzoyl-(thio) ureas
ZA856584B (en) 1-(2-trifluoromethoxy-phenylsulphonyl)-3-heteroaryl-(thio)ureas
DE3369912D1 (en) Process for the calcination of phosphorus-molybdenum catalyst
GB8404096D0 (en) Manufacturing articles from paint sludge
GB8415124D0 (en) (3-aryl-5-isothiazolyl)ureas
GB8316325D0 (en) Catalyst component production
DE3567019D1 (en) 1-(2-oxyaminosulfonylphenyl-sulfonyl)-3-heteroaryl ureas
AU568648B2 (en) 1,2,3-thiazole-3-in-5-ylidine ureas
GB2138321B (en) Ceramic coatings
GB8301786D0 (en) Child-proof catches
IE830073L (en) Ureas and related compounds
GB8412433D0 (en) Coatings
IE810480L (en) Ureas & thioureas