ZA836658B - Hepatitis b virus vaccine - Google Patents

Hepatitis b virus vaccine

Info

Publication number
ZA836658B
ZA836658B ZA836658A ZA836658A ZA836658B ZA 836658 B ZA836658 B ZA 836658B ZA 836658 A ZA836658 A ZA 836658A ZA 836658 A ZA836658 A ZA 836658A ZA 836658 B ZA836658 B ZA 836658B
Authority
ZA
South Africa
Prior art keywords
hepatitis
virus vaccine
yeast
hbsag
gene
Prior art date
Application number
ZA836658A
Other languages
English (en)
Inventor
Theresa Cabezon
Marjolene Crabeel
Michel De Wilde
Nigel Harford
Original Assignee
Smith Kline Rit
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith Kline Rit filed Critical Smith Kline Rit
Publication of ZA836658B publication Critical patent/ZA836658B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00Reverse transcribing DNA viruses
    • C12N2730/00011Details
    • C12N2730/10011Hepadnaviridae
    • C12N2730/10111Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
ZA836658A 1982-09-08 1983-09-07 Hepatitis b virus vaccine ZA836658B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US41578982A 1982-09-08 1982-09-08

Publications (1)

Publication Number Publication Date
ZA836658B true ZA836658B (en) 1984-06-27

Family

ID=23647197

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA836658A ZA836658B (en) 1982-09-08 1983-09-07 Hepatitis b virus vaccine

Country Status (22)

Country Link
EP (1) EP0106828B1 (de)
JP (5) JPS5971694A (de)
KR (1) KR840006014A (de)
AT (1) ATE91718T1 (de)
AU (4) AU584580B2 (de)
CA (1) CA1222707A (de)
CY (1) CY1932A (de)
DE (1) DE3382704T2 (de)
DK (1) DK406483A (de)
ES (4) ES525439A0 (de)
FI (1) FI833205A (de)
GR (1) GR78982B (de)
HK (1) HK1004570A1 (de)
HU (1) HU196625B (de)
IE (1) IE60387B1 (de)
IL (1) IL69202A (de)
MA (1) MA19895A1 (de)
MY (1) MY102920A (de)
NO (1) NO833198L (de)
NZ (1) NZ204952A (de)
PT (1) PT77265B (de)
ZA (1) ZA836658B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5931799A (ja) * 1982-08-16 1984-02-20 Science & Tech Agency B型肝炎ウイルス遺伝子を組込んだ組換えプラスミド
JPS5936699A (ja) * 1982-08-20 1984-02-28 Chemo Sero Therapeut Res Inst シヤトルベクタ−
WO1986007384A1 (en) * 1985-06-03 1986-12-18 Takeda Chemical Industries, Ltd. Process for preparing hapatitis b virus surface antigen p31
WO1986001534A1 (en) * 1984-09-04 1986-03-13 Takeda Chemical Industries, Ltd. Recombinant dna and its use
WO1986003411A1 (en) * 1984-12-12 1986-06-19 Takeda Chemical Industries, Ltd. Process for preparing novel protein
US4683294A (en) * 1985-04-03 1987-07-28 Smith Kline Rit, S.A. Process for the extraction and purification of proteins from culture media producing them
EP0211767B1 (de) * 1985-08-05 1991-03-06 Merck & Co. Inc. Verfahren zur Steigerung der Produktion von rekombinantem Protein in Hefearten der Gattung Saccharomyces
US4895800A (en) * 1985-11-26 1990-01-23 Phillips Petroleum Company Yeast production of hepatitis B surface antigen
AP56A (en) * 1987-01-30 1989-09-26 Smithkline Biologicals S A Hepatitis B virus surface antigens and hybrid antigehs containing them.
ATE93891T1 (de) * 1987-03-09 1993-09-15 Merck & Co Inc Reinigung von rekombiniertem hepatitis-boberfl|chen-antigen.
NZ229260A (en) * 1988-06-03 1994-02-25 Merck & Co Inc Hepatitis b virus, expression cassette for pre-s domain, host cells and
US4962656A (en) * 1989-06-30 1990-10-16 The United States Of America As Represented By The United States Department Of Energy Control and monitoring method and system for electromagnetic forming process
LT3988B (en) 1992-02-17 1996-06-25 Fermentas Biotech Inst Recombinant plasmides pfs19, pfps2-48 and pjlfds1 codingsynthesis of human hepatite b of surfice virus antigenes, methods fof producing thereof
TW340132B (en) * 1994-10-20 1998-09-11 Ibm Structure for use as an electrical interconnection means and process for preparing the same
JP4028850B2 (ja) * 2004-02-04 2007-12-26 株式会社名機製作所 ディスク基板の成形用金型

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2530801B2 (ja) * 1978-12-22 1996-09-04 バイオゲン インコーポレイテッド 組換えdna分子
NZ199722A (en) * 1981-02-25 1985-12-13 Genentech Inc Dna transfer vector for expression of exogenous polypeptide in yeast;transformed yeast strain
GR76274B (de) * 1981-08-04 1984-08-04 Univ California
NZ201705A (en) * 1981-08-31 1986-03-14 Genentech Inc Recombinant dna method for production of hepatitis b surface antigen in yeast
GB2125047B (en) * 1982-08-09 1986-02-19 Ciba Geigy Ag Yeast hybrid vectors and their use for the production of polypeptides

Also Published As

Publication number Publication date
GR78982B (de) 1984-10-02
NZ204952A (en) 1986-05-09
ES8506350A1 (es) 1985-07-01
IE832099L (en) 1984-03-08
EP0106828A2 (de) 1984-04-25
IL69202A (en) 1991-08-16
JPH08317796A (ja) 1996-12-03
DK406483A (da) 1984-03-09
JP2702899B2 (ja) 1998-01-26
AU1569288A (en) 1988-07-28
EP0106828B1 (de) 1993-07-21
DE3382704D1 (de) 1993-08-26
HU196625B (en) 1988-12-28
DK406483D0 (da) 1983-09-07
ES8602120A1 (es) 1985-11-01
JPH02231084A (ja) 1990-09-13
ATE91718T1 (de) 1993-08-15
MY102920A (en) 1993-03-31
ES532732A0 (es) 1985-10-16
ES8600939A1 (es) 1985-10-16
PT77265A (en) 1983-09-01
PT77265B (en) 1986-02-04
JPH02116A (ja) 1990-01-05
ES532730A0 (es) 1985-10-16
IE60387B1 (en) 1994-07-13
HK1004570A1 (en) 1998-11-27
KR840006014A (ko) 1984-11-21
JPH02464A (ja) 1990-01-05
ES8600938A1 (es) 1985-10-16
NO833198L (no) 1984-03-09
ES525439A0 (es) 1985-07-01
EP0106828A3 (en) 1985-11-21
FI833205A (fi) 1984-03-09
MA19895A1 (fr) 1984-04-01
AU1675083A (en) 1984-03-15
ES532731A0 (es) 1985-11-01
DE3382704T2 (de) 1994-02-10
CY1932A (en) 1983-09-06
AU3131889A (en) 1989-07-20
FI833205A0 (fi) 1983-09-07
CA1222707A (en) 1987-06-09
JPS5971694A (ja) 1984-04-23
AU9001491A (en) 1992-02-27
AU584580B2 (en) 1989-06-01
JP2522825B2 (ja) 1996-08-07

Similar Documents

Publication Publication Date Title
IE832099L (en) Hepatitis b virus vaccine
EP0291586A3 (de) Rekombinantes Hepatitis-B-Oberflächenantigen und dieses enthaltender Impfstoff
IL69423A0 (en) Recombinant plasmid inserted with hepatitis b virus gene,yeast transformed with said recombinant plasmid and production of hepatitis b virus surface antigen
DE3280284D1 (de) Herstellung von oberflaechen-hepatitis-b-antigen in hefe.
IE800991L (en) HBs Ag GENE AND PRODUCT
EP0171908A3 (de) Hepatitis-B-Virus-Oberflächenantigen und dessen Herstellung
DE3280186D1 (de) Synthese von menschlichen viralen antigenen mit hilfe von hefe.
IL90035A (en) Synthetic multimeric hepatitis b virus vaccine including both t cell and b cell determinants
EP0105149A3 (en) Recombinant plasmid containing hepatitis b virus gene, yeast transformed with said recombinant plasmid, and production of hepatitis b virus surface antigen
EP0171260A3 (en) Hepatitis b vaccine
GR3023985T3 (en) Expression of hepatitis B S and preS2 proteins in methylotrophic yeasts
EP0037723A3 (de) Expression von genomischen Klonen von Hormonen
EP0152030A3 (de) Adult-T-Zell-Leukemiavirus-Antigenpolypeptid
ES8602935A1 (es) Un vector reversible
JPS6467191A (en) Recombinant dna plasmid having integrated hepatitis b virus gene, transformed animal cell, hepatitis b viral surface antigen protein and production thereof
SU1380209A1 (ru) РЕКОМБИНАНТНАЯ ПЛАЗМИДНАЯ ДНК PUR 291-HAV 22, КОДИРУЮЩАЯ СИНТЕЗ ГИБРИДНОГО ПОЛИПЕПТИДА АНТИГЕННЫХ ДЕТЕРМИНАНТ ВИРУСА ГЕПАТИТА А С β -ГАЛАКТОЗИДАЗОЙ
RU1651555C (ru) Рекомбинантна плазмидна ДНК р7,5С, кодирующа антиген вируса гепатита В, и способ ее конструировани
FI861559A (fi) Menetelmä hepatitis B-viruksen pinta-antigeenin PreS1-PreS2-S-proteiinin koodaavan alueen koodaamia proteiineja käsittävän proteiinin valmistamiseksi sekä menetelmässä käytettävät yhdistelmä-DNA-vektorit ja -kontameerit sekä nisäkässolut
ATE53235T1 (de) Synthese von menschlichen viralen antigenen mit hilfe von hefe.