AU3131889A - Hepatitis b virus vaccine - Google Patents

Hepatitis b virus vaccine

Info

Publication number
AU3131889A
AU3131889A AU31318/89A AU3131889A AU3131889A AU 3131889 A AU3131889 A AU 3131889A AU 31318/89 A AU31318/89 A AU 31318/89A AU 3131889 A AU3131889 A AU 3131889A AU 3131889 A AU3131889 A AU 3131889A
Authority
AU
Australia
Prior art keywords
hepatitis
virus vaccine
yeast
hbsag
gene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU31318/89A
Inventor
Theresa Cabezon
Marjolene Crabeel
Michel De Wilde
Nigel Harford
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlaxoSmithKline Biologicals SA
Original Assignee
SmithKline RIT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline RIT filed Critical SmithKline RIT
Publication of AU3131889A publication Critical patent/AU3131889A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Mycology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

A DNA fragment capable of coding for HBsAg and DNA derivatives of Dane particles is fused to the region for controlling the arg3 gene of yeast and cloned in a yeast vector. The recombinant vector is employed for transforming the competent yeast cells in which the HBsAg gene is expressed.
AU31318/89A 1982-09-08 1989-03-14 Hepatitis b virus vaccine Abandoned AU3131889A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US41578982A 1982-09-08 1982-09-08
US415789 1982-09-08

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
AU16750/83A Division AU584580B2 (en) 1982-09-08 1983-07-12 Hepatitis B virus vaccine

Publications (1)

Publication Number Publication Date
AU3131889A true AU3131889A (en) 1989-07-20

Family

ID=23647197

Family Applications (4)

Application Number Title Priority Date Filing Date
AU16750/83A Ceased AU584580B2 (en) 1982-09-08 1983-07-12 Hepatitis B virus vaccine
AU15692/88A Abandoned AU1569288A (en) 1982-09-08 1988-05-06 Hepatitis b virus vaccine
AU31318/89A Abandoned AU3131889A (en) 1982-09-08 1989-03-14 Hepatitis b virus vaccine
AU90014/91A Abandoned AU9001491A (en) 1982-09-08 1991-12-24 Hepatitis b virus vaccine

Family Applications Before (2)

Application Number Title Priority Date Filing Date
AU16750/83A Ceased AU584580B2 (en) 1982-09-08 1983-07-12 Hepatitis B virus vaccine
AU15692/88A Abandoned AU1569288A (en) 1982-09-08 1988-05-06 Hepatitis b virus vaccine

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU90014/91A Abandoned AU9001491A (en) 1982-09-08 1991-12-24 Hepatitis b virus vaccine

Country Status (22)

Country Link
EP (1) EP0106828B1 (en)
JP (5) JPS5971694A (en)
KR (1) KR840006014A (en)
AT (1) ATE91718T1 (en)
AU (4) AU584580B2 (en)
CA (1) CA1222707A (en)
CY (1) CY1932A (en)
DE (1) DE3382704T2 (en)
DK (1) DK406483A (en)
ES (4) ES8506350A1 (en)
FI (1) FI833205A (en)
GR (1) GR78982B (en)
HK (1) HK1004570A1 (en)
HU (1) HU196625B (en)
IE (1) IE60387B1 (en)
IL (1) IL69202A (en)
MA (1) MA19895A1 (en)
MY (1) MY102920A (en)
NO (1) NO833198L (en)
NZ (1) NZ204952A (en)
PT (1) PT77265B (en)
ZA (1) ZA836658B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU616976B2 (en) * 1988-06-03 1991-11-14 Merck & Co., Inc. Method for producing nonhyperglycosylated hepatitis b virus proteins

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5931799A (en) * 1982-08-16 1984-02-20 Science & Tech Agency Recombinant plasmid and preparation of transformed yeast and hepatitis virus b surface antigen using the same
JPS5936699A (en) * 1982-08-20 1984-02-28 Chemo Sero Therapeut Res Inst Shuttle vector
WO1986003411A1 (en) * 1984-12-12 1986-06-19 Takeda Chemical Industries, Ltd. Process for preparing novel protein
WO1986001534A1 (en) * 1984-09-04 1986-03-13 Takeda Chemical Industries, Ltd. Recombinant dna and its use
WO1986007384A1 (en) * 1985-06-03 1986-12-18 Takeda Chemical Industries, Ltd. Process for preparing hapatitis b virus surface antigen p31
US4683294A (en) * 1985-04-03 1987-07-28 Smith Kline Rit, S.A. Process for the extraction and purification of proteins from culture media producing them
DE3677851D1 (en) * 1985-08-05 1991-04-11 Merck & Co Inc METHOD FOR INCREASING THE PRODUCTION OF RECOMBINANT PROTEIN IN YEARS OF THE GENERATION SACCHAROMYCES.
US4895800A (en) * 1985-11-26 1990-01-23 Phillips Petroleum Company Yeast production of hepatitis B surface antigen
AP56A (en) * 1987-01-30 1989-09-26 Smithkline Biologicals S A Hepatitis B virus surface antigens and hybrid antigehs containing them.
EP0291146B1 (en) * 1987-03-09 1993-09-01 Merck & Co. Inc. Purification of recombinant hepatitis b surface antigen
US4962656A (en) * 1989-06-30 1990-10-16 The United States Of America As Represented By The United States Department Of Energy Control and monitoring method and system for electromagnetic forming process
LT3988B (en) 1992-02-17 1996-06-25 Fermentas Biotech Inst Recombinant plasmides pfs19, pfps2-48 and pjlfds1 codingsynthesis of human hepatite b of surfice virus antigenes, methods fof producing thereof
TW340132B (en) * 1994-10-20 1998-09-11 Ibm Structure for use as an electrical interconnection means and process for preparing the same
JP4028850B2 (en) * 2004-02-04 2007-12-26 株式会社名機製作所 Mold for molding disk substrate

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR73675B (en) * 1978-12-22 1984-03-29 Biogen Inc
NZ199722A (en) * 1981-02-25 1985-12-13 Genentech Inc Dna transfer vector for expression of exogenous polypeptide in yeast;transformed yeast strain
GR76274B (en) * 1981-08-04 1984-08-04 Univ California
NZ201705A (en) * 1981-08-31 1986-03-14 Genentech Inc Recombinant dna method for production of hepatitis b surface antigen in yeast
GB2125047B (en) * 1982-08-09 1986-02-19 Ciba Geigy Ag Yeast hybrid vectors and their use for the production of polypeptides

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU616976B2 (en) * 1988-06-03 1991-11-14 Merck & Co., Inc. Method for producing nonhyperglycosylated hepatitis b virus proteins

Also Published As

Publication number Publication date
EP0106828A3 (en) 1985-11-21
HU196625B (en) 1988-12-28
JPS5971694A (en) 1984-04-23
KR840006014A (en) 1984-11-21
IE832099L (en) 1984-03-08
ATE91718T1 (en) 1993-08-15
ES525439A0 (en) 1985-07-01
AU1675083A (en) 1984-03-15
HK1004570A1 (en) 1998-11-27
CA1222707A (en) 1987-06-09
MY102920A (en) 1993-03-31
ES8600939A1 (en) 1985-10-16
EP0106828B1 (en) 1993-07-21
ES532731A0 (en) 1985-11-01
ES532732A0 (en) 1985-10-16
FI833205A0 (en) 1983-09-07
FI833205A (en) 1984-03-09
AU1569288A (en) 1988-07-28
AU9001491A (en) 1992-02-27
ES8600938A1 (en) 1985-10-16
PT77265B (en) 1986-02-04
IE60387B1 (en) 1994-07-13
IL69202A (en) 1991-08-16
JPH02116A (en) 1990-01-05
ES8602120A1 (en) 1985-11-01
CY1932A (en) 1983-09-06
DE3382704D1 (en) 1993-08-26
DE3382704T2 (en) 1994-02-10
PT77265A (en) 1983-09-01
DK406483D0 (en) 1983-09-07
ES8506350A1 (en) 1985-07-01
JP2522825B2 (en) 1996-08-07
AU584580B2 (en) 1989-06-01
JPH02464A (en) 1990-01-05
NO833198L (en) 1984-03-09
ZA836658B (en) 1984-06-27
EP0106828A2 (en) 1984-04-25
GR78982B (en) 1984-10-02
NZ204952A (en) 1986-05-09
JPH02231084A (en) 1990-09-13
DK406483A (en) 1984-03-09
MA19895A1 (en) 1984-04-01
JP2702899B2 (en) 1998-01-26
JPH08317796A (en) 1996-12-03
ES532730A0 (en) 1985-10-16

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