IL69202A - Surface antigen polypeptides of hbv virus produced in yeast and the preparation thereof - Google Patents

Surface antigen polypeptides of hbv virus produced in yeast and the preparation thereof

Info

Publication number
IL69202A
IL69202A IL69202A IL6920283A IL69202A IL 69202 A IL69202 A IL 69202A IL 69202 A IL69202 A IL 69202A IL 6920283 A IL6920283 A IL 6920283A IL 69202 A IL69202 A IL 69202A
Authority
IL
Israel
Prior art keywords
yeast
preparation
surface antigen
virus produced
antigen polypeptides
Prior art date
Application number
IL69202A
Other languages
English (en)
Original Assignee
Smith Kline Rit
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith Kline Rit filed Critical Smith Kline Rit
Publication of IL69202A publication Critical patent/IL69202A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00Reverse transcribing DNA viruses
    • C12N2730/00011Details
    • C12N2730/10011Hepadnaviridae
    • C12N2730/10111Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
IL69202A 1982-09-08 1983-07-12 Surface antigen polypeptides of hbv virus produced in yeast and the preparation thereof IL69202A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US41578982A 1982-09-08 1982-09-08

Publications (1)

Publication Number Publication Date
IL69202A true IL69202A (en) 1991-08-16

Family

ID=23647197

Family Applications (1)

Application Number Title Priority Date Filing Date
IL69202A IL69202A (en) 1982-09-08 1983-07-12 Surface antigen polypeptides of hbv virus produced in yeast and the preparation thereof

Country Status (22)

Country Link
EP (1) EP0106828B1 (xx)
JP (5) JPS5971694A (xx)
KR (1) KR840006014A (xx)
AT (1) ATE91718T1 (xx)
AU (4) AU584580B2 (xx)
CA (1) CA1222707A (xx)
CY (1) CY1932A (xx)
DE (1) DE3382704T2 (xx)
DK (1) DK406483A (xx)
ES (4) ES8506350A1 (xx)
FI (1) FI833205A (xx)
GR (1) GR78982B (xx)
HK (1) HK1004570A1 (xx)
HU (1) HU196625B (xx)
IE (1) IE60387B1 (xx)
IL (1) IL69202A (xx)
MA (1) MA19895A1 (xx)
MY (1) MY102920A (xx)
NO (1) NO833198L (xx)
NZ (1) NZ204952A (xx)
PT (1) PT77265B (xx)
ZA (1) ZA836658B (xx)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5936699A (ja) * 1982-08-20 1984-02-28 Chemo Sero Therapeut Res Inst シヤトルベクタ−
JPS5931799A (ja) * 1982-08-16 1984-02-20 Science & Tech Agency B型肝炎ウイルス遺伝子を組込んだ組換えプラスミド
WO1986007384A1 (en) * 1985-06-03 1986-12-18 Takeda Chemical Industries, Ltd. Process for preparing hapatitis b virus surface antigen p31
WO1986001534A1 (en) * 1984-09-04 1986-03-13 Takeda Chemical Industries, Ltd. Recombinant dna and its use
WO1986003411A1 (en) * 1984-12-12 1986-06-19 Takeda Chemical Industries, Ltd. Process for preparing novel protein
US4683294A (en) * 1985-04-03 1987-07-28 Smith Kline Rit, S.A. Process for the extraction and purification of proteins from culture media producing them
DE3677851D1 (de) * 1985-08-05 1991-04-11 Merck & Co Inc Verfahren zur steigerung der produktion von rekombinantem protein in hefearten der gattung saccharomyces.
US4895800A (en) * 1985-11-26 1990-01-23 Phillips Petroleum Company Yeast production of hepatitis B surface antigen
EP0278940A3 (en) * 1987-01-30 1988-12-07 Smithkline Biologicals S.A. Hepatitis b virus surface antigens and hybrid antigens containing them
DE3883596T2 (de) * 1987-03-09 1994-02-17 Merck & Co Inc Reinigung von rekombiniertem Hepatitis-B-Oberflächen-Antigen.
NZ229260A (en) * 1988-06-03 1994-02-25 Merck & Co Inc Hepatitis b virus, expression cassette for pre-s domain, host cells and
US4962656A (en) * 1989-06-30 1990-10-16 The United States Of America As Represented By The United States Department Of Energy Control and monitoring method and system for electromagnetic forming process
LT3988B (en) 1992-02-17 1996-06-25 Fermentas Biotech Inst Recombinant plasmides pfs19, pfps2-48 and pjlfds1 codingsynthesis of human hepatite b of surfice virus antigenes, methods fof producing thereof
TW340132B (en) * 1994-10-20 1998-09-11 Ibm Structure for use as an electrical interconnection means and process for preparing the same
JP4028850B2 (ja) * 2004-02-04 2007-12-26 株式会社名機製作所 ディスク基板の成形用金型

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES8105035A1 (es) * 1978-12-22 1981-05-16 Biogen Nv Un metodo para producir al menos un polipeptido que muestra antigenicidad de hbv
NZ199722A (en) * 1981-02-25 1985-12-13 Genentech Inc Dna transfer vector for expression of exogenous polypeptide in yeast;transformed yeast strain
GR76274B (xx) * 1981-08-04 1984-08-04 Univ California
NZ201705A (en) * 1981-08-31 1986-03-14 Genentech Inc Recombinant dna method for production of hepatitis b surface antigen in yeast
GB2125047B (en) * 1982-08-09 1986-02-19 Ciba Geigy Ag Yeast hybrid vectors and their use for the production of polypeptides

Also Published As

Publication number Publication date
HU196625B (en) 1988-12-28
ZA836658B (en) 1984-06-27
EP0106828B1 (fr) 1993-07-21
FI833205A0 (fi) 1983-09-07
PT77265A (en) 1983-09-01
DE3382704T2 (de) 1994-02-10
AU1569288A (en) 1988-07-28
JPS5971694A (ja) 1984-04-23
ES532732A0 (es) 1985-10-16
EP0106828A2 (fr) 1984-04-25
AU3131889A (en) 1989-07-20
MA19895A1 (fr) 1984-04-01
ES532730A0 (es) 1985-10-16
ES8602120A1 (es) 1985-11-01
ES532731A0 (es) 1985-11-01
IE60387B1 (en) 1994-07-13
MY102920A (en) 1993-03-31
JPH02116A (ja) 1990-01-05
JP2702899B2 (ja) 1998-01-26
JP2522825B2 (ja) 1996-08-07
DK406483D0 (da) 1983-09-07
ES8600939A1 (es) 1985-10-16
DK406483A (da) 1984-03-09
CA1222707A (en) 1987-06-09
NZ204952A (en) 1986-05-09
AU584580B2 (en) 1989-06-01
DE3382704D1 (de) 1993-08-26
FI833205A (fi) 1984-03-09
ATE91718T1 (de) 1993-08-15
ES525439A0 (es) 1985-07-01
JPH08317796A (ja) 1996-12-03
PT77265B (en) 1986-02-04
HK1004570A1 (en) 1998-11-27
EP0106828A3 (en) 1985-11-21
JPH02464A (ja) 1990-01-05
ES8506350A1 (es) 1985-07-01
NO833198L (no) 1984-03-09
IE832099L (en) 1984-03-08
KR840006014A (ko) 1984-11-21
AU9001491A (en) 1992-02-27
ES8600938A1 (es) 1985-10-16
AU1675083A (en) 1984-03-15
CY1932A (en) 1983-09-06
GR78982B (xx) 1984-10-02
JPH02231084A (ja) 1990-09-13

Similar Documents

Publication Publication Date Title
IL69202A (en) Surface antigen polypeptides of hbv virus produced in yeast and the preparation thereof
EP0291586A3 (en) Recombinant hepatitis b surface antigen and vaccine containing it
EP0271302A3 (en) T cell epitopes of the hepatitis b virus nucleocapsid protein
EP0171908A3 (en) Hepatitis b virus surface antigen and production thereof
DE3280186D1 (de) Synthese von menschlichen viralen antigenen mit hilfe von hefe.
IL69423A0 (en) Recombinant plasmid inserted with hepatitis b virus gene,yeast transformed with said recombinant plasmid and production of hepatitis b virus surface antigen
EP0101617A3 (en) Recombinant dna containing a hepatitis b virus gene, mammalian cells transformed with the cloned viral dna, and production of hepatitis b virus proteins
IL90035A (en) Synthetic multimeric hepatitis b virus vaccine including both t cell and b cell determinants
GR3023985T3 (en) Expression of hepatitis B S and preS2 proteins in methylotrophic yeasts
EP0105149A3 (en) Recombinant plasmid containing hepatitis b virus gene, yeast transformed with said recombinant plasmid, and production of hepatitis b virus surface antigen
AU598181B2 (en) Composition useful for obtaining vaccines containing particles carrying the surface antigene of hepatitis b virus and the receptor of polymerized human serum albumin, animal cells capable of producing such particles and method for the obtention thereof
ES8602935A1 (es) Un vector reversible
JPS6467191A (en) Recombinant dna plasmid having integrated hepatitis b virus gene, transformed animal cell, hepatitis b viral surface antigen protein and production thereof
FI861559A (fi) Menetelmä hepatitis B-viruksen pinta-antigeenin PreS1-PreS2-S-proteiinin koodaavan alueen koodaamia proteiineja käsittävän proteiinin valmistamiseksi sekä menetelmässä käytettävät yhdistelmä-DNA-vektorit ja -kontameerit sekä nisäkässolut

Legal Events

Date Code Title Description
RH Patent void