ZA824537B - Compounds - Google Patents

Compounds

Info

Publication number
ZA824537B
ZA824537B ZA824537A ZA824537A ZA824537B ZA 824537 B ZA824537 B ZA 824537B ZA 824537 A ZA824537 A ZA 824537A ZA 824537 A ZA824537 A ZA 824537A ZA 824537 B ZA824537 B ZA 824537B
Authority
ZA
South Africa
Prior art keywords
pyridyl
sub
oxo
sup
dimethyl
Prior art date
Application number
ZA824537A
Other languages
English (en)
Inventor
George Sidney Sach
Original Assignee
Smith Kline French Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith Kline French Lab filed Critical Smith Kline French Lab
Publication of ZA824537B publication Critical patent/ZA824537B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/04Drugs for disorders of the respiratory system for throat disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61Halogen atoms or nitro radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/63One oxygen atom
    • C07D213/65One oxygen atom attached in position 3 or 5
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/73Unsubstituted amino or imino radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Treating Waste Gases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Luminescent Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA824537A 1981-06-27 1982-06-25 Compounds ZA824537B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8119906 1981-06-27

Publications (1)

Publication Number Publication Date
ZA824537B true ZA824537B (en) 1983-05-25

Family

ID=10522859

Family Applications (2)

Application Number Title Priority Date Filing Date
ZA824537A ZA824537B (en) 1981-06-27 1982-06-25 Compounds
ZA824580A ZA824580B (en) 1981-06-27 1982-06-28 Compounds

Family Applications After (1)

Application Number Title Priority Date Filing Date
ZA824580A ZA824580B (en) 1981-06-27 1982-06-28 Compounds

Country Status (27)

Country Link
US (4) US4444772A (pl)
EP (2) EP0068833B1 (pl)
JP (4) JPS588080A (pl)
KR (1) KR880001475B1 (pl)
AT (2) ATE21900T1 (pl)
AU (2) AU8535282A (pl)
BG (1) BG38163A3 (pl)
CS (1) CS241036B2 (pl)
DD (1) DD202291A5 (pl)
DE (2) DE3273019D1 (pl)
DK (2) DK287082A (pl)
ES (1) ES8305755A1 (pl)
FI (1) FI822281L (pl)
GR (2) GR74925B (pl)
HU (1) HU190396B (pl)
IE (1) IE53348B1 (pl)
IL (1) IL66125A (pl)
JO (1) JO1185B1 (pl)
NO (1) NO822120L (pl)
NZ (1) NZ201077A (pl)
PH (1) PH19680A (pl)
PL (3) PL138524B1 (pl)
PT (1) PT75074B (pl)
SU (1) SU1232145A3 (pl)
YU (1) YU138982A (pl)
ZA (2) ZA824537B (pl)
ZW (1) ZW13082A1 (pl)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN151188B (pl) * 1978-02-13 1983-03-05 Smith Kline French Lab
US4808589A (en) * 1982-02-20 1989-02-28 Smith Kline & French Laboratories Limited Pyrimidone derivatives
ATE33832T1 (de) * 1982-03-25 1988-05-15 Smith Kline French Lab Verfahren zur herstellung von 3,5disubstituierten 2-pyridylalkylaminen.
GR78463B (pl) * 1982-03-25 1984-09-27 Smith Kline French Lab
PT77287B (en) * 1982-10-01 1986-02-04 Smith Kline French Lab Compound
GB8319874D0 (en) * 1983-07-23 1983-08-24 Smith Kline French Lab Compounds
CA1286297C (en) * 1985-06-13 1991-07-16 George S. Sach Pyridine derivatives
GB8601816D0 (en) * 1986-01-25 1986-02-26 Smith Kline French Lab Pyridine derivatives
GB8610867D0 (en) * 1986-05-02 1986-06-11 Smith Kline French Lab 3-hydroxypyridines
JP2679977B2 (ja) * 1986-09-19 1997-11-19 株式会社日立製作所 半導体集積回路
EP0364584A4 (en) * 1988-04-27 1990-12-05 Kievsky Nauchno-Issledovatelsky Institut Farmakologii I Toxikologii Antidote for organic phosphorus compound poisoning
US5216170A (en) * 1989-01-26 1993-06-01 Bayer Aktiengesellschaft (2-aminopropyl) pyridines useful as intermediates
KR100498005B1 (ko) * 2002-07-26 2005-07-01 주식회사 소하드 기능성 액상비료 및 그 제조방법
CA2510860C (en) * 2002-12-20 2012-10-09 Exxonmobil Chemical Patents Inc. Polymerization process utilizing hydrofluorocarbons as diluents
US7443103B2 (en) * 2005-06-24 2008-10-28 General Electric Company High pressure lamp with lamp flicker suppression and lamp voltage control
JP2011527311A (ja) * 2008-07-10 2011-10-27 ノバルティス アーゲー Bace阻害薬として有用なアミノベンジル置換環状スルホン誘導体

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN146736B (pl) * 1975-10-02 1979-08-25 Smith Kline French Lab
US4216318A (en) * 1975-12-29 1980-08-05 Smith Kline & French Laboratories Limited Heterocyclic alkyl 4-pyrimidones
MW5076A1 (en) * 1975-12-29 1978-02-08 Smith Kline French Lab Pharmacologicalle active compounds
US4154834A (en) * 1975-12-29 1979-05-15 Smith Kline & French Laboratories Limited Substituted isocytosines having histamine H2 -antagonist activity
US4227000A (en) * 1978-04-11 1980-10-07 Smith Kline & French Laboratories Limited Intermediates in the process for making histamine antagonists
ZA792608B (en) * 1978-05-30 1980-06-25 Smith Kline French Lab Nitro compounds
US4255428A (en) * 1979-03-24 1981-03-10 Smith Kline & French Laboratories Limited 5-(Hydroxypyridylalkyl)-4-pyrimidones
JPS55133379A (en) * 1979-04-05 1980-10-17 Smith Kline French Lab Pyrimidone compound
DE2962542D1 (en) * 1979-04-11 1982-06-03 Smith Kline French Lab Pyrimidone derivatives, process for preparing them and pharmaceutical compositions containing them
JPS55145683A (en) * 1979-04-26 1980-11-13 Smith Kline French Lab Pyrimidone derivative

Also Published As

Publication number Publication date
PL137600B1 (en) 1986-07-31
JPH0244812B2 (pl) 1990-10-05
PL240628A1 (en) 1983-10-10
JPH0345073B2 (pl) 1991-07-09
GR74926B (pl) 1984-07-12
ES513469A0 (es) 1983-05-01
GR74925B (pl) 1984-07-12
IL66125A (en) 1986-01-31
ATE21900T1 (de) 1986-09-15
PL138524B1 (en) 1986-09-30
EP0068834A3 (en) 1983-04-06
IE53348B1 (en) 1988-10-26
PH19680A (en) 1986-06-13
IE821533L (en) 1982-12-27
HU190396B (en) 1986-08-28
DE3273782D1 (en) 1986-11-20
EP0068833A3 (en) 1983-03-30
JO1185B1 (en) 1983-11-30
ATE22891T1 (de) 1986-11-15
FI822281A0 (fi) 1982-06-24
BG38163A3 (en) 1985-10-15
JPS588079A (ja) 1983-01-18
CS241036B2 (en) 1986-03-13
DE3273019D1 (en) 1986-10-09
US4486434A (en) 1984-12-04
NZ201077A (en) 1985-09-13
PL137627B1 (en) 1986-07-31
PT75074B (en) 1986-02-26
EP0068834A2 (en) 1983-01-05
NO822120L (no) 1982-12-28
ZA824580B (en) 1983-05-25
FI822281L (fi) 1982-12-28
JPS61233670A (ja) 1986-10-17
SU1232145A3 (ru) 1986-05-15
CS480082A2 (en) 1985-06-13
YU138982A (en) 1985-03-20
EP0068834B1 (en) 1986-09-03
KR840000533A (ko) 1984-02-25
US4535163A (en) 1985-08-13
ZW13082A1 (en) 1982-09-29
JPS588080A (ja) 1983-01-18
US4584381A (en) 1986-04-22
PT75074A (en) 1982-07-01
KR880001475B1 (ko) 1988-08-13
JPS6328424B2 (pl) 1988-06-08
JPS61233616A (ja) 1986-10-17
DK286982A (da) 1982-12-28
AU8535282A (en) 1983-01-06
AU8535182A (en) 1983-01-06
EP0068833A2 (en) 1983-01-05
EP0068833B1 (en) 1986-10-15
PL237110A1 (en) 1983-06-20
DD202291A5 (de) 1983-09-07
IL66125A0 (en) 1982-09-30
DK287082A (da) 1982-12-28
ES8305755A1 (es) 1983-05-01
US4444772A (en) 1984-04-24
AU551066B2 (en) 1986-04-17

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