JPS5959632A
(ja)
*
|
1982-09-28 |
1984-04-05 |
Teikoku Chem Ind Corp Ltd |
徐放性組成物
|
US4713245A
(en)
*
|
1984-06-04 |
1987-12-15 |
Mitsui Toatsu Chemicals, Incorporated |
Granule containing physiologically-active substance, method for preparing same and use thereof
|
JPS6150912A
(ja)
*
|
1984-08-16 |
1986-03-13 |
Shionogi & Co Ltd |
リポソ−ム製剤の製造法
|
US4755387A
(en)
*
|
1985-03-21 |
1988-07-05 |
The Procter & Gamble Company |
Therapeutic particles
|
FR2581541B1
(fr)
*
|
1985-05-09 |
1988-05-20 |
Rhone Poulenc Sante |
Nouvelles compositions pharmaceutiques permettant la liberation prolongee d'un principe actif et leur procede de preparation
|
US4820523A
(en)
*
|
1986-04-15 |
1989-04-11 |
Warner-Lambert Company |
Pharmaceutical composition
|
US4837381A
(en)
*
|
1986-08-11 |
1989-06-06 |
American Cyanamid Company |
Compositions for parenteral administration and their use
|
US4822619A
(en)
*
|
1987-02-18 |
1989-04-18 |
Ionor, Inc. |
Controlled release pharmaceutical preparation containing a gastrointestinal irritant drug
|
JP2668880B2
(ja)
*
|
1987-06-23 |
1997-10-27 |
日本油脂株式会社 |
被覆アミノ酸類の製造方法
|
DE3737741A1
(de)
*
|
1987-11-06 |
1989-05-18 |
Goedecke Ag |
Oral anzuwendende arzneiform zur einmal taeglichen behandlung der hypertonie mit diltiazemhydrochlorid
|
JP2681373B2
(ja)
*
|
1988-07-18 |
1997-11-26 |
塩野義製薬株式会社 |
徐放性製剤の製造法
|
EP0418596A3
(en)
*
|
1989-09-21 |
1991-10-23 |
American Cyanamid Company |
Controlled release pharmaceutical compositions from spherical granules in tabletted oral dosage unit form
|
US5213810A
(en)
*
|
1990-03-30 |
1993-05-25 |
American Cyanamid Company |
Stable compositions for parenteral administration and method of making same
|
IE61651B1
(en)
*
|
1990-07-04 |
1994-11-16 |
Zambon Spa |
Programmed release oral solid pharmaceutical dosage form
|
US5134016A
(en)
*
|
1990-10-31 |
1992-07-28 |
E. I. Du Pont De Nemours And Company |
Fiber reinforced porous sheets
|
US5266331A
(en)
*
|
1991-11-27 |
1993-11-30 |
Euroceltique, S.A. |
Controlled release oxycodone compositions
|
US5958459A
(en)
*
|
1991-12-24 |
1999-09-28 |
Purdue Pharma L.P. |
Opioid formulations having extended controlled released
|
US5478577A
(en)
*
|
1993-11-23 |
1995-12-26 |
Euroceltique, S.A. |
Method of treating pain by administering 24 hour oral opioid formulations exhibiting rapid rate of initial rise of plasma drug level
|
US5968551A
(en)
*
|
1991-12-24 |
1999-10-19 |
Purdue Pharma L.P. |
Orally administrable opioid formulations having extended duration of effect
|
US5792474A
(en)
*
|
1992-05-22 |
1998-08-11 |
Goedecke Aktiengesellschaft |
Process for the production of retarded pharmaceutical compositions
|
IL119660A
(en)
*
|
1993-05-10 |
2002-09-12 |
Euro Celtique Sa |
Controlled release formulation comprising tramadol
|
IL110014A
(en)
*
|
1993-07-01 |
1999-11-30 |
Euro Celtique Sa |
Solid controlled-release oral dosage forms of opioid analgesics
|
US7740881B1
(en)
|
1993-07-01 |
2010-06-22 |
Purdue Pharma Lp |
Method of treating humans with opioid formulations having extended controlled release
|
US5879705A
(en)
*
|
1993-07-27 |
1999-03-09 |
Euro-Celtique S.A. |
Sustained release compositions of morphine and a method of preparing pharmaceutical compositions
|
KR100354702B1
(ko)
*
|
1993-11-23 |
2002-12-28 |
유로-셀티크 소시에떼 아노뉨 |
약학조성물의제조방법및서방형조성물
|
US5891471A
(en)
*
|
1993-11-23 |
1999-04-06 |
Euro-Celtique, S.A. |
Pharmaceutical multiparticulates
|
US5843480A
(en)
*
|
1994-03-14 |
1998-12-01 |
Euro-Celtique, S.A. |
Controlled release diamorphine formulation
|
GB9422154D0
(en)
|
1994-11-03 |
1994-12-21 |
Euro Celtique Sa |
Pharmaceutical compositions and method of producing the same
|
US5965161A
(en)
|
1994-11-04 |
1999-10-12 |
Euro-Celtique, S.A. |
Extruded multi-particulates
|
JP3768536B2
(ja)
*
|
1995-04-03 |
2006-04-19 |
アボツト・ラボラトリーズ |
低温溶融性薬物と制御放出のための添加物との均質混合物
|
DE19522899C1
(de)
*
|
1995-06-23 |
1996-12-19 |
Hexal Pharmaforschung Gmbh |
Verfahren zum kontinuierlichen Ersintern eines Granulats
|
AU709262B2
(en)
*
|
1995-10-17 |
1999-08-26 |
Board Of Regents, The University Of Texas System |
Insoluble drug delivery
|
US7255877B2
(en)
|
1996-08-22 |
2007-08-14 |
Jagotec Ag |
Fenofibrate microparticles
|
US6465016B2
(en)
|
1996-08-22 |
2002-10-15 |
Research Triangle Pharmaceuticals |
Cyclosporiine particles
|
DE19705538C1
(de)
*
|
1997-02-14 |
1998-08-27 |
Goedecke Ag |
Verfahren zur Trennung von Wirkstoffen in festen pharmazeutischen Zubereitungen
|
US5891476A
(en)
*
|
1997-12-22 |
1999-04-06 |
Reo; Joe P. |
Tastemasked pharmaceutical system
|
WO1999040906A2
(en)
*
|
1998-02-11 |
1999-08-19 |
Research Triangle Pharmaceuticals |
Method and composition for treatment of inflammatory conditions
|
US6979456B1
(en)
|
1998-04-01 |
2005-12-27 |
Jagotec Ag |
Anticancer compositions
|
ATE259220T1
(de)
|
1998-05-29 |
2004-02-15 |
Skyepharma Canada Inc |
Gegen hitzeeinwirkung geschützte mikropartikel und verfahren zur terminalen dampfsterilisation derselben
|
US7097849B2
(en)
|
1998-08-19 |
2006-08-29 |
Jagotec Ag |
Injectable aqueous dispersions of propofol
|
US6806294B2
(en)
|
1998-10-15 |
2004-10-19 |
Euro-Celtique S.A. |
Opioid analgesic
|
RU2233654C2
(ru)
|
1998-11-20 |
2004-08-10 |
Ртп Фарма Инк. |
Диспергируемые стабилизированные фосфолипидом микрочастицы
|
DE19918325A1
(de)
|
1999-04-22 |
2000-10-26 |
Euro Celtique Sa |
Verfahren zur Herstellung von Arzneiformen mit regulierter Wirkstofffreisetzung mittels Extrusion
|
KR20020011985A
(ko)
*
|
1999-05-07 |
2002-02-09 |
파르마솔 게엠베하 |
액상 및 고체상 지질 혼합물에 기초한 지질입자들 및 그의제조방법
|
ES2374717T3
(es)
|
1999-10-29 |
2012-02-21 |
Euro-Celtique S.A. |
Formulaciones de hidrocodona de liberación controlada.
|
US10179130B2
(en)
|
1999-10-29 |
2019-01-15 |
Purdue Pharma L.P. |
Controlled release hydrocodone formulations
|
ES2469642T3
(es)
|
2000-04-20 |
2014-06-18 |
Jagotec Ag |
Procedimiento mejorado para partículas de fármaco insoluble en agua
|
US6634576B2
(en)
|
2000-08-31 |
2003-10-21 |
Rtp Pharma Inc. |
Milled particles
|
US8586094B2
(en)
|
2000-09-20 |
2013-11-19 |
Jagotec Ag |
Coated tablets
|
JP2004512354A
(ja)
|
2000-10-30 |
2004-04-22 |
ユーロ−セルティーク,エス.エイ. |
ヒドロコドン放出制御製剤
|
AU2002219198B2
(en)
*
|
2000-12-27 |
2006-06-29 |
Ares Trading S.A. |
Lipid microparticles by cryogenic micronization
|
US7776314B2
(en)
|
2002-06-17 |
2010-08-17 |
Grunenthal Gmbh |
Abuse-proofed dosage system
|
DE10300325A1
(de)
|
2003-01-09 |
2004-07-22 |
Hexal Ag |
Granulat mit öliger Substanz, Herstellungsverfahren und Tablette
|
CA2509958A1
(en)
|
2003-02-03 |
2004-08-19 |
Novartis Ag |
Pharmaceutical formulation
|
DE10336400A1
(de)
|
2003-08-06 |
2005-03-24 |
Grünenthal GmbH |
Gegen Missbrauch gesicherte Darreichungsform
|
US8075872B2
(en)
|
2003-08-06 |
2011-12-13 |
Gruenenthal Gmbh |
Abuse-proofed dosage form
|
DE102004032051A1
(de)
|
2004-07-01 |
2006-01-19 |
Grünenthal GmbH |
Verfahren zur Herstellung einer gegen Missbrauch gesicherten, festen Darreichungsform
|
DE10361596A1
(de)
|
2003-12-24 |
2005-09-29 |
Grünenthal GmbH |
Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
|
DE102005005446A1
(de)
|
2005-02-04 |
2006-08-10 |
Grünenthal GmbH |
Bruchfeste Darreichungsformen mit retardierter Freisetzung
|
US20070048228A1
(en)
|
2003-08-06 |
2007-03-01 |
Elisabeth Arkenau-Maric |
Abuse-proofed dosage form
|
ES2653568T3
(es)
|
2004-06-12 |
2018-02-07 |
Collegium Pharmaceutical, Inc. |
Formulaciones de fármacos para la prevención del abuso
|
DE102004032049A1
(de)
|
2004-07-01 |
2006-01-19 |
Grünenthal GmbH |
Gegen Missbrauch gesicherte, orale Darreichungsform
|
DE102005005449A1
(de)
|
2005-02-04 |
2006-08-10 |
Grünenthal GmbH |
Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
|
AU2007275033A1
(en)
*
|
2006-07-21 |
2008-01-24 |
Lab International Srl |
Hydrophobic abuse deterrent delivery system
|
DE102007011485A1
(de)
|
2007-03-07 |
2008-09-11 |
Grünenthal GmbH |
Darreichungsform mit erschwertem Missbrauch
|
US20110059140A1
(en)
*
|
2007-12-21 |
2011-03-10 |
Gerhard Winter |
Extruded rod-shaped devices for controlled release of biological substances to humans and animals
|
EP2249811A1
(de)
|
2008-01-25 |
2010-11-17 |
Grünenthal GmbH |
Pharmazeutische dosierform
|
CA2723438C
(en)
|
2008-05-09 |
2016-10-11 |
Gruenenthal Gmbh |
Process for the preparation of an intermediate powder formulation and a final solid dosage form under usage of a spray congealing step
|
WO2011009602A1
(en)
|
2009-07-22 |
2011-01-27 |
Grünenthal GmbH |
Hot-melt extruded controlled release dosage form
|
BR112012001244A2
(pt)
|
2009-07-22 |
2020-12-08 |
Gruünenthal Gmbh |
Forma de dosagem resitente à adulteração, seu processo de produção, e embalagem contendo tal forma
|
US10668060B2
(en)
|
2009-12-10 |
2020-06-02 |
Collegium Pharmaceutical, Inc. |
Tamper-resistant pharmaceutical compositions of opioids and other drugs
|
US9579285B2
(en)
|
2010-02-03 |
2017-02-28 |
Gruenenthal Gmbh |
Preparation of a powdery pharmaceutical composition by means of an extruder
|
AR082862A1
(es)
|
2010-09-02 |
2013-01-16 |
Gruenenthal Gmbh |
Forma de dosificacion resistente a alteracion que comprende un polimero anionico
|
RU2604676C2
(ru)
|
2010-09-02 |
2016-12-10 |
Грюненталь Гмбх |
Устойчивая к разрушению лекарственная форма, содержащая неорганическую соль
|
BR112014002022A2
(pt)
|
2011-07-29 |
2017-02-21 |
Gruenenthal Gmbh |
comprimido resistente à violação proporcionando liberação de fármaco imediata
|
PT2736497T
(pt)
|
2011-07-29 |
2017-11-30 |
Gruenenthal Gmbh |
Comprimido resistente a adulteração proporcionando libertação imediata de fármaco
|
CA2864949A1
(en)
|
2012-02-28 |
2013-09-06 |
Grunenthal Gmbh |
Tamper-resistant dosage form comprising pharmacologically active compound and anionic polymer
|
ES2692944T3
(es)
|
2012-04-18 |
2018-12-05 |
Grünenthal GmbH |
Forma de dosificación farmacéutica resistente a la manipulación y resistente a la descarga rápida de la dosis
|
US10064945B2
(en)
|
2012-05-11 |
2018-09-04 |
Gruenenthal Gmbh |
Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc
|
MX371432B
(es)
|
2013-05-29 |
2020-01-30 |
Gruenenthal Gmbh |
Forma de dosificacion resistente al uso indebido que contiene una o mas particulas.
|
MX2015016254A
(es)
|
2013-05-29 |
2016-04-20 |
Gruenenthal Gmbh |
Forma de dosificacion resistente al uso indebido con perfil de liberacion bimodal.
|
US10624862B2
(en)
|
2013-07-12 |
2020-04-21 |
Grünenthal GmbH |
Tamper-resistant dosage form containing ethylene-vinyl acetate polymer
|
CN105934241B
(zh)
|
2013-11-26 |
2020-06-05 |
格吕伦塔尔有限公司 |
通过低温研磨制备粉末状药物组合物
|
WO2015173195A1
(en)
|
2014-05-12 |
2015-11-19 |
Grünenthal GmbH |
Tamper resistant immediate release capsule formulation comprising tapentadol
|
AU2015266117A1
(en)
|
2014-05-26 |
2016-11-24 |
Grunenthal Gmbh |
Multiparticles safeguarded against ethanolic dose-dumping
|
MX2017001625A
(es)
*
|
2014-08-11 |
2017-07-28 |
Perora Gmbh |
Metodo para la induccion de saciedad.
|
CN107889459A
(zh)
|
2015-04-24 |
2018-04-06 |
格吕伦塔尔有限公司 |
具有立即释放和对溶剂萃取的抗性的抗篡改剂型
|
US10842750B2
(en)
|
2015-09-10 |
2020-11-24 |
Grünenthal GmbH |
Protecting oral overdose with abuse deterrent immediate release formulations
|
WO2017222575A1
(en)
|
2016-06-23 |
2017-12-28 |
Collegium Pharmaceutical, Inc. |
Process of making more stable abuse-deterrent oral formulations
|
EP3492070A1
(de)
*
|
2017-11-30 |
2019-06-05 |
BIT Pharma GmbH |
Verfahren und vorrichtung zur herstellung einer festen dispersion
|