ZA201904188B - Combination therapy for the treatment of cancer - Google Patents

Combination therapy for the treatment of cancer

Info

Publication number
ZA201904188B
ZA201904188B ZA2019/04188A ZA201904188A ZA201904188B ZA 201904188 B ZA201904188 B ZA 201904188B ZA 2019/04188 A ZA2019/04188 A ZA 2019/04188A ZA 201904188 A ZA201904188 A ZA 201904188A ZA 201904188 B ZA201904188 B ZA 201904188B
Authority
ZA
South Africa
Prior art keywords
cancer
treatment
combination therapy
therapy
combination
Prior art date
Application number
ZA2019/04188A
Other languages
English (en)
Inventor
C Strum Jay
R Thatcher Gregory
Xiong Rui
zhao Jiong
A Tonetti Debra
Original Assignee
G1 Therapeutics Inc
Univ Illinois
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by G1 Therapeutics Inc, Univ Illinois filed Critical G1 Therapeutics Inc
Publication of ZA201904188B publication Critical patent/ZA201904188B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA2019/04188A 2017-01-06 2019-06-26 Combination therapy for the treatment of cancer ZA201904188B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762443588P 2017-01-06 2017-01-06
PCT/US2018/012675 WO2018129387A1 (en) 2017-01-06 2018-01-05 Combination therapy for the treatment of cancer

Publications (1)

Publication Number Publication Date
ZA201904188B true ZA201904188B (en) 2022-12-21

Family

ID=62791140

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2019/04188A ZA201904188B (en) 2017-01-06 2019-06-26 Combination therapy for the treatment of cancer

Country Status (15)

Country Link
US (1) US11364222B2 (https=)
EP (1) EP3565558B1 (https=)
JP (1) JP7229162B2 (https=)
KR (1) KR102576011B1 (https=)
CN (1) CN110177554B (https=)
AR (1) AR110728A1 (https=)
AU (2) AU2018205262A1 (https=)
CA (1) CA3048057A1 (https=)
EA (1) EA201991622A1 (https=)
IL (1) IL267795B2 (https=)
MX (1) MX2019008158A (https=)
NZ (1) NZ754865A (https=)
TW (1) TWI823845B (https=)
WO (1) WO2018129387A1 (https=)
ZA (1) ZA201904188B (https=)

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CN111386113A (zh) 2017-12-01 2020-07-07 诺华股份有限公司 包含lsz102和阿培利司的药物组合
CN112424205B (zh) * 2018-07-12 2023-10-31 伊莱利利公司 选择性的雌激素受体降解剂
JP7571006B2 (ja) 2018-08-17 2024-10-22 ジェネンテック， インコーポレイテッド 乳がんの処置のための診断的および治療的方法
CN113271977A (zh) * 2018-11-09 2021-08-17 G1治疗公司 使用艾日布林和选择性cdk4/6抑制剂组合治疗癌症的治疗方案
CN112840402B (zh) * 2019-09-02 2024-05-07 北京哲源科技有限责任公司 获得细胞内确定性事件的方法及电子设备
US20230073301A1 (en) * 2020-01-27 2023-03-09 Isola Therapeutics, Inc. Tissue dosing for intraluminal local drug delivery
KR20230012547A (ko) 2020-05-19 2023-01-26 쥐원 쎄라퓨틱스, 인크. 의학적 장애의 치료를 위한 시클린-의존성 키나제 억제 화합물
US10988479B1 (en) 2020-06-15 2021-04-27 G1 Therapeutics, Inc. Morphic forms of trilaciclib and methods of manufacture thereof
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