PL3630754T3 - Związki izoindolinoacetylenowe do leczenia nowotworu - Google Patents
Związki izoindolinoacetylenowe do leczenia nowotworuInfo
- Publication number
- PL3630754T3 PL3630754T3 PL18728875.8T PL18728875T PL3630754T3 PL 3630754 T3 PL3630754 T3 PL 3630754T3 PL 18728875 T PL18728875 T PL 18728875T PL 3630754 T3 PL3630754 T3 PL 3630754T3
- Authority
- PL
- Poland
- Prior art keywords
- isoindoline
- cancer
- treatment
- acetylene compounds
- acetylene
- Prior art date
Links
- ZLBLXSFSZKWMGE-UHFFFAOYSA-N C#C.C1NCc2ccccc12 Chemical group C#C.C1NCc2ccccc12 ZLBLXSFSZKWMGE-UHFFFAOYSA-N 0.000 title 1
- 206010028980 Neoplasm Diseases 0.000 title 1
- 201000011510 cancer Diseases 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762514244P | 2017-06-02 | 2017-06-02 | |
| EP17174334 | 2017-06-02 | ||
| US201762543438P | 2017-08-10 | 2017-08-10 | |
| PCT/EP2018/064399 WO2018220149A1 (en) | 2017-06-02 | 2018-06-01 | Compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3630754T3 true PL3630754T3 (pl) | 2022-10-24 |
Family
ID=62495802
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL18728875.8T PL3630754T3 (pl) | 2017-06-02 | 2018-06-01 | Związki izoindolinoacetylenowe do leczenia nowotworu |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US11117890B2 (pl) |
| EP (1) | EP3630754B8 (pl) |
| JP (1) | JP7191045B2 (pl) |
| KR (1) | KR20200015595A (pl) |
| CN (1) | CN110753691B (pl) |
| AU (1) | AU2018276441B2 (pl) |
| BR (1) | BR112019025370A2 (pl) |
| CA (1) | CA3065874A1 (pl) |
| CL (1) | CL2019003501A1 (pl) |
| CO (1) | CO2019013557A2 (pl) |
| CR (1) | CR20190542A (pl) |
| ES (1) | ES2927480T3 (pl) |
| IL (1) | IL271013B2 (pl) |
| MA (1) | MA48946A (pl) |
| MX (1) | MX390898B (pl) |
| MY (1) | MY201976A (pl) |
| PE (1) | PE20200718A1 (pl) |
| PH (1) | PH12019502662A1 (pl) |
| PL (1) | PL3630754T3 (pl) |
| TW (1) | TWI774780B (pl) |
| UA (1) | UA126452C2 (pl) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020254572A1 (en) | 2019-06-21 | 2020-12-24 | F. Hoffmann-La Roche Ag | Egfr inhibitors for the treatment of cancer |
| CN118525018A (zh) * | 2021-12-21 | 2024-08-20 | 上海艾力斯医药科技股份有限公司 | 一种联炔类化合物及其应用 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5386350B2 (ja) | 2006-05-31 | 2014-01-15 | タケダ カリフォルニア インコーポレイテッド | グルコキナーゼ活性剤としての、インダゾールおよびイソインドール誘導体 |
| JP2010530736A (ja) * | 2007-05-25 | 2010-09-16 | バーンハム インスティトゥート フォー メディカル リサーチ | タプシガルジンにより誘導される細胞死の阻害剤 |
| US20110212078A1 (en) * | 2008-06-25 | 2011-09-01 | Reddy Panduranga Adulla P | Synthesis and use of heterocyclic antibacterial agents |
| US8420661B2 (en) * | 2010-04-13 | 2013-04-16 | Hoffmann-La Roche Inc. | Arylethynyl derivatives |
| CN102060848B (zh) | 2010-12-09 | 2013-09-18 | 天津药物研究院 | 芳香胺取代的嘧啶衍生物的制备及用途 |
| CN102093339B (zh) | 2010-12-09 | 2013-06-12 | 天津药物研究院 | 一类嘧啶衍生物的制备及用途 |
| WO2013170774A1 (zh) * | 2012-05-16 | 2013-11-21 | 上海医药集团股份有限公司 | 具有抗肿瘤活性的乙炔衍生物 |
| TW201607930A (zh) * | 2014-07-18 | 2016-03-01 | 百濟神州有限公司 | 作為ｔ７９０ｍ／ｗｔ－ｅｇｆｒ的選擇性和不可逆的激酶抑制劑的５－氨基－４－氨甲醯基－吡唑化合物及其用途 |
| SI3205650T1 (sl) * | 2014-10-11 | 2021-10-29 | Shanghai Hansoh Biomedical Co Ltd | Zaviralec EGFR-ja in priprava ter uporaba le-tega |
| JP6771491B2 (ja) * | 2015-05-14 | 2020-10-21 | ザ ウィスター インスティテュート オブ アナトミー アンド バイオロジー | Ｅｂｎａ１阻害剤およびその使用方法 |
| US10385019B2 (en) * | 2015-06-30 | 2019-08-20 | Dana-Farber Cancer Institute, Inc. | Inhibitors of EGFR and methods of use thereof |
| TW201834651A (zh) | 2016-12-22 | 2018-10-01 | 瑞士商赫孚孟拉羅股份公司 | 化合物 |
-
2018
- 2018-06-01 TW TW107118846A patent/TWI774780B/zh not_active IP Right Cessation
- 2018-06-01 CA CA3065874A patent/CA3065874A1/en active Pending
- 2018-06-01 PL PL18728875.8T patent/PL3630754T3/pl unknown
- 2018-06-01 KR KR1020197038496A patent/KR20200015595A/ko not_active Ceased
- 2018-06-01 UA UAA202000003A patent/UA126452C2/uk unknown
- 2018-06-01 BR BR112019025370-0A patent/BR112019025370A2/pt not_active IP Right Cessation
- 2018-06-01 MX MX2019014332A patent/MX390898B/es unknown
- 2018-06-01 MY MYPI2019007060A patent/MY201976A/en unknown
- 2018-06-01 EP EP18728875.8A patent/EP3630754B8/en active Active
- 2018-06-01 MA MA048946A patent/MA48946A/fr unknown
- 2018-06-01 CN CN201880036589.7A patent/CN110753691B/zh active Active
- 2018-06-01 ES ES18728875T patent/ES2927480T3/es active Active
- 2018-06-01 CR CR20190542A patent/CR20190542A/es unknown
- 2018-06-01 JP JP2019566634A patent/JP7191045B2/ja active Active
- 2018-06-01 PE PE2019002464A patent/PE20200718A1/es unknown
- 2018-06-01 AU AU2018276441A patent/AU2018276441B2/en not_active Ceased
-
2019
- 2019-11-25 PH PH12019502662A patent/PH12019502662A1/en unknown
- 2019-11-28 IL IL271013A patent/IL271013B2/en unknown
- 2019-11-29 CO CONC2019/0013557A patent/CO2019013557A2/es unknown
- 2019-11-29 CL CL2019003501A patent/CL2019003501A1/es unknown
- 2019-12-02 US US16/700,900 patent/US11117890B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| IL271013B2 (en) | 2023-02-01 |
| RU2019143647A (ru) | 2021-07-09 |
| PE20200718A1 (es) | 2020-07-21 |
| MX2019014332A (es) | 2022-03-24 |
| UA126452C2 (uk) | 2022-10-05 |
| PH12019502662A1 (en) | 2020-06-08 |
| CL2019003501A1 (es) | 2020-06-05 |
| EP3630754A1 (en) | 2020-04-08 |
| TWI774780B (zh) | 2022-08-21 |
| US20200102299A1 (en) | 2020-04-02 |
| CN110753691A (zh) | 2020-02-04 |
| MY201976A (en) | 2024-03-27 |
| TW201902892A (zh) | 2019-01-16 |
| US11117890B2 (en) | 2021-09-14 |
| AU2018276441B2 (en) | 2022-04-28 |
| KR20200015595A (ko) | 2020-02-12 |
| IL271013B (en) | 2022-10-01 |
| AU2018276441A1 (en) | 2019-12-12 |
| EP3630754B1 (en) | 2022-07-27 |
| RU2019143647A3 (pl) | 2021-09-28 |
| CA3065874A1 (en) | 2018-12-06 |
| CO2019013557A2 (es) | 2020-01-17 |
| EP3630754B8 (en) | 2022-08-31 |
| MX390898B (es) | 2025-03-21 |
| CR20190542A (es) | 2020-01-14 |
| MA48946A (fr) | 2020-04-08 |
| JP2020524659A (ja) | 2020-08-20 |
| ES2927480T3 (es) | 2022-11-07 |
| IL271013A (en) | 2020-01-30 |
| JP7191045B2 (ja) | 2022-12-16 |
| BR112019025370A2 (pt) | 2020-06-23 |
| CN110753691B (zh) | 2024-02-02 |
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