ZA201306148B - Use of 3-(5-amino-2-methyl-4-oxoquinazolin-3(4h)-yl)piperidine-2-6-dione in treatment of immune-related and inflammatory diseases - Google Patents

Use of 3-(5-amino-2-methyl-4-oxoquinazolin-3(4h)-yl)piperidine-2-6-dione in treatment of immune-related and inflammatory diseases

Info

Publication number
ZA201306148B
ZA201306148B ZA2013/06148A ZA201306148A ZA201306148B ZA 201306148 B ZA201306148 B ZA 201306148B ZA 2013/06148 A ZA2013/06148 A ZA 2013/06148A ZA 201306148 A ZA201306148 A ZA 201306148A ZA 201306148 B ZA201306148 B ZA 201306148B
Authority
ZA
South Africa
Prior art keywords
oxoquinazolin
dione
piperidine
immune
amino
Prior art date
Application number
ZA2013/06148A
Other languages
English (en)
Inventor
Anita Gandhi
Peter H Schafer
Original Assignee
Celgene Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celgene Corp filed Critical Celgene Corp
Publication of ZA201306148B publication Critical patent/ZA201306148B/en

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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
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    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
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    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
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    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
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    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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ZA2013/06148A 2011-03-11 2013-08-15 Use of 3-(5-amino-2-methyl-4-oxoquinazolin-3(4h)-yl)piperidine-2-6-dione in treatment of immune-related and inflammatory diseases ZA201306148B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161451995P 2011-03-11 2011-03-11
US201161480272P 2011-04-28 2011-04-28
PCT/US2012/028538 WO2012125475A1 (en) 2011-03-11 2012-03-09 Use of 3-(5-amino-2-methyl-4-oxoquinazolin-3(4h)-yl)piperidine-2-6-dione in treatment of immune-related and inflammatory diseases

Publications (1)

Publication Number Publication Date
ZA201306148B true ZA201306148B (en) 2014-10-29

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ZA2013/06148A ZA201306148B (en) 2011-03-11 2013-08-15 Use of 3-(5-amino-2-methyl-4-oxoquinazolin-3(4h)-yl)piperidine-2-6-dione in treatment of immune-related and inflammatory diseases
ZA2013/06305A ZA201306305B (en) 2011-03-11 2013-08-21 Methods of treating cancer using 3-(5-amino-2-methyl-4h-quinazolin-3-yl)-piperidine-2,6-dione

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ZA2013/06305A ZA201306305B (en) 2011-03-11 2013-08-21 Methods of treating cancer using 3-(5-amino-2-methyl-4h-quinazolin-3-yl)-piperidine-2,6-dione

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US (6) US8906932B2 (https=)
EP (3) EP3025715A1 (https=)
JP (5) JP6118273B2 (https=)
KR (2) KR20140019364A (https=)
CN (3) CN103561743A (https=)
AR (1) AR085651A1 (https=)
AU (4) AU2012229300B2 (https=)
BR (2) BR112013023280A2 (https=)
CA (2) CA2829593A1 (https=)
CY (1) CY1117430T1 (https=)
DK (1) DK2683384T3 (https=)
EA (2) EA201391319A1 (https=)
ES (2) ES2562332T3 (https=)
HR (1) HRP20160056T1 (https=)
HU (1) HUE027481T2 (https=)
IL (2) IL227990B (https=)
MX (2) MX2013010153A (https=)
NI (2) NI201300081A (https=)
PH (2) PH12013501820A1 (https=)
PL (1) PL2683384T3 (https=)
PT (1) PT2683384E (https=)
RS (1) RS54553B1 (https=)
RU (3) RU2013145556A (https=)
SG (2) SG193320A1 (https=)
SI (1) SI2683384T1 (https=)
SM (1) SMT201600034B (https=)
TW (2) TWI542349B (https=)
WO (2) WO2012125459A1 (https=)
ZA (2) ZA201306148B (https=)

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