ZA200900961B - Benzimidazole derivatives useful in treatment of vallinoid receptor TRPV1 related disorders - Google Patents

Benzimidazole derivatives useful in treatment of vallinoid receptor TRPV1 related disorders

Info

Publication number
ZA200900961B
ZA200900961B ZA200900961A ZA200900961A ZA200900961B ZA 200900961 B ZA200900961 B ZA 200900961B ZA 200900961 A ZA200900961 A ZA 200900961A ZA 200900961 A ZA200900961 A ZA 200900961A ZA 200900961 B ZA200900961 B ZA 200900961B
Authority
ZA
South Africa
Prior art keywords
treatment
related disorders
benzimidazole derivatives
derivatives useful
receptor trpv1
Prior art date
Application number
ZA200900961A
Other languages
English (en)
Inventor
William Brown
Shawn Johnstone
Denis Labrecque
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39033277&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA200900961(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of ZA200900961B publication Critical patent/ZA200900961B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA200900961A 2006-08-11 2009-02-10 Benzimidazole derivatives useful in treatment of vallinoid receptor TRPV1 related disorders ZA200900961B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US83724906P 2006-08-11 2006-08-11

Publications (1)

Publication Number Publication Date
ZA200900961B true ZA200900961B (en) 2010-07-28

Family

ID=39033277

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200900961A ZA200900961B (en) 2006-08-11 2009-02-10 Benzimidazole derivatives useful in treatment of vallinoid receptor TRPV1 related disorders

Country Status (25)

Country Link
US (2) US7906654B2 (xx)
EP (1) EP2051967B1 (xx)
JP (1) JP5140077B2 (xx)
KR (1) KR101412881B1 (xx)
CN (2) CN101522637A (xx)
AR (1) AR062299A1 (xx)
AU (1) AU2007282186B2 (xx)
BR (1) BRPI0715746B8 (xx)
CA (1) CA2660529C (xx)
CL (1) CL2007002343A1 (xx)
CO (1) CO6150176A2 (xx)
ES (1) ES2533971T3 (xx)
IL (1) IL196672A0 (xx)
MX (1) MX2009001496A (xx)
MY (1) MY147649A (xx)
NO (1) NO20091054L (xx)
NZ (1) NZ575416A (xx)
PE (1) PE20081315A1 (xx)
RU (1) RU2458055C2 (xx)
SG (1) SG173360A1 (xx)
TW (1) TWI433839B (xx)
UA (1) UA96764C2 (xx)
UY (1) UY30533A1 (xx)
WO (1) WO2008018827A1 (xx)
ZA (1) ZA200900961B (xx)

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TWI433839B (zh) * 2006-08-11 2014-04-11 Neomed Inst 新穎的苯并咪唑衍生物290
EP2025674A1 (de) 2007-08-15 2009-02-18 sanofi-aventis Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
CN101983197B (zh) 2008-04-18 2015-04-22 大熊制药株式会社 新型苯并噁嗪苯并咪唑衍生物、含有该衍生物的药物组合物及其用途
KR101293384B1 (ko) 2010-10-13 2013-08-05 주식회사 대웅제약 신규 피리딜 벤조옥사진 유도체, 이를 포함하는 약학 조성물 및 이의 용도
CN104640857B (zh) 2012-07-18 2017-07-04 圣路易斯大学 作为整合素拮抗剂的β氨基酸衍生物
US8716226B2 (en) 2012-07-18 2014-05-06 Saint Louis University 3,5 phenyl-substituted beta amino acid derivatives as integrin antagonists
JO3719B1 (ar) 2014-11-20 2021-01-31 Takeda Pharmaceuticals Co 4- أوكسو-4،3- داي هيدرو-3،2،1- بنزوترايازينات كمواد ضابطة لأجل gpr139
EP3230330B1 (en) 2014-12-08 2020-09-30 Rohm and Haas Company A polyolefin additive, a sag resistant polyolefin and a method of preparing the same
JP2018052817A (ja) * 2015-01-21 2018-04-05 大日本住友製薬株式会社 新規ベンズイミダゾール誘導体およびその医薬用途
SG11201805387RA (en) 2015-12-30 2018-07-30 Univ Saint Louis Meta-azacyclic amino benzoic acid derivatives as pan integrin antagonists
KR20210148081A (ko) * 2019-01-08 2021-12-07 네오메드 인스티튜트 (s)-2-(7-시아노-1h-벤즈이미다졸-1 일)-n-(1-(4-(1-시아노-1-메틸에틸)페닐)에틸)아세트아미드의 결정 형태
RU2755206C1 (ru) 2020-05-20 2021-09-14 Федеральное государственное бюджетное учреждение науки Тихоокеанский институт биоорганической химии им. Г.Б. Елякова Дальневосточного отделения Российской академии наук (ТИБОХ ДВО РАН) Средство пролонгированного анальгетического действия и лекарственный препарат на его основе

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Also Published As

Publication number Publication date
US7906654B2 (en) 2011-03-15
EP2051967A1 (en) 2009-04-29
UY30533A1 (es) 2008-03-31
KR101412881B1 (ko) 2014-06-26
ES2533971T3 (es) 2015-04-16
RU2458055C2 (ru) 2012-08-10
NZ575416A (en) 2011-10-28
WO2008018827A1 (en) 2008-02-14
UA96764C2 (ru) 2011-12-12
MY147649A (en) 2012-12-31
EP2051967B1 (en) 2014-12-31
CN101522637A (zh) 2009-09-02
WO2008018827A8 (en) 2009-02-19
CA2660529C (en) 2014-10-21
BRPI0715746A2 (pt) 2013-07-16
CA2660529A1 (en) 2008-02-14
IL196672A0 (en) 2009-11-18
AU2007282186B2 (en) 2011-07-07
JP5140077B2 (ja) 2013-02-06
BRPI0715746B1 (pt) 2020-09-24
US8093402B2 (en) 2012-01-10
TW200817338A (en) 2008-04-16
RU2009103675A (ru) 2010-09-20
EP2051967A4 (en) 2011-06-29
CL2007002343A1 (es) 2008-04-04
MX2009001496A (es) 2009-02-18
SG173360A1 (en) 2011-08-29
AU2007282186A1 (en) 2008-02-14
CN101792436A (zh) 2010-08-04
AR062299A1 (es) 2008-10-29
TWI433839B (zh) 2014-04-11
CO6150176A2 (es) 2010-04-20
US20080221188A1 (en) 2008-09-11
US20110137045A1 (en) 2011-06-09
KR20090035701A (ko) 2009-04-10
PE20081315A1 (es) 2008-11-08
JP2010500345A (ja) 2010-01-07
BRPI0715746B8 (pt) 2021-05-25
NO20091054L (no) 2009-03-09

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