NO20091054L - Benzimidazolderivater anvendelige for behandling av vallinoidreceptor TRPV1 relaterte forstyrrelser - Google Patents

Benzimidazolderivater anvendelige for behandling av vallinoidreceptor TRPV1 relaterte forstyrrelser

Info

Publication number
NO20091054L
NO20091054L NO20091054A NO20091054A NO20091054L NO 20091054 L NO20091054 L NO 20091054L NO 20091054 A NO20091054 A NO 20091054A NO 20091054 A NO20091054 A NO 20091054A NO 20091054 L NO20091054 L NO 20091054L
Authority
NO
Norway
Prior art keywords
treatment
benzimidazole derivatives
related disorders
derivatives useful
receptor trpv1
Prior art date
Application number
NO20091054A
Other languages
English (en)
Inventor
William Brown
Shawn Johnstone
Denis Labrecque
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39033277&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20091054(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of NO20091054L publication Critical patent/NO20091054L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Abstract

Foreliggende oppfinnelse tilveiebringer benzimidazolderivater, antagonister av VRI, fremgangsmåter for deres fremstilling, farmasøytiske sammensetninger som inneholder dem og deres anvendelse ved behandling. Forbindelsene med formel I kan anvendes ved behandling av osteoartritt, kronisk tendinitt, pelvisk smerte og perifer neuropati, gastro-spiserørreflukssykdom, irritabelt tarmsyndrom og overaktiv blære.
NO20091054A 2006-08-11 2009-03-09 Benzimidazolderivater anvendelige for behandling av vallinoidreceptor TRPV1 relaterte forstyrrelser NO20091054L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83724906P 2006-08-11 2006-08-11
PCT/SE2007/000720 WO2008018827A1 (en) 2006-08-11 2007-08-10 Benzimidazole derivatives useful in treatment of vallinoid receptor trpv1 related disorders

Publications (1)

Publication Number Publication Date
NO20091054L true NO20091054L (no) 2009-03-09

Family

ID=39033277

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20091054A NO20091054L (no) 2006-08-11 2009-03-09 Benzimidazolderivater anvendelige for behandling av vallinoidreceptor TRPV1 relaterte forstyrrelser

Country Status (25)

Country Link
US (2) US7906654B2 (no)
EP (1) EP2051967B1 (no)
JP (1) JP5140077B2 (no)
KR (1) KR101412881B1 (no)
CN (2) CN101792436A (no)
AR (1) AR062299A1 (no)
AU (1) AU2007282186B2 (no)
BR (1) BRPI0715746B8 (no)
CA (1) CA2660529C (no)
CL (1) CL2007002343A1 (no)
CO (1) CO6150176A2 (no)
ES (1) ES2533971T3 (no)
IL (1) IL196672A0 (no)
MX (1) MX2009001496A (no)
MY (1) MY147649A (no)
NO (1) NO20091054L (no)
NZ (1) NZ575416A (no)
PE (1) PE20081315A1 (no)
RU (1) RU2458055C2 (no)
SG (1) SG173360A1 (no)
TW (1) TWI433839B (no)
UA (1) UA96764C2 (no)
UY (1) UY30533A1 (no)
WO (1) WO2008018827A1 (no)
ZA (1) ZA200900961B (no)

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US8716226B2 (en) 2012-07-18 2014-05-06 Saint Louis University 3,5 phenyl-substituted beta amino acid derivatives as integrin antagonists
WO2014015054A1 (en) 2012-07-18 2014-01-23 Saint Louis University Beta amino acid derivatives as integrin antagonists
JO3719B1 (ar) 2014-11-20 2021-01-31 Takeda Pharmaceuticals Co 4- أوكسو-4،3- داي هيدرو-3،2،1- بنزوترايازينات كمواد ضابطة لأجل gpr139
JP6853778B2 (ja) 2014-12-08 2021-03-31 ローム アンド ハース カンパニーＲｏｈｍ Ａｎｄ Ｈａａｓ Ｃｏｍｐａｎｙ ポリオレフィン添加剤、耐垂下性ポリオレフィン、及びその調製方法
JP2018052817A (ja) * 2015-01-21 2018-04-05 大日本住友製薬株式会社 新規ベンズイミダゾール誘導体およびその医薬用途
CN108779077A (zh) 2015-12-30 2018-11-09 圣路易斯大学 作为pan整合素拮抗剂的间位氮杂环氨基苯甲酸衍生物
US20220089550A1 (en) * 2019-01-08 2022-03-24 Neomed Institute - Institut Neomed Crystalline forms of (s)-2-(7-cyano-1h-benzimidazol-1 yl)-n-{1-[4-(1-cyano-1-methylethyl)phenyl]ethyl}acetamide
RU2755206C1 (ru) 2020-05-20 2021-09-14 Федеральное государственное бюджетное учреждение науки Тихоокеанский институт биоорганической химии им. Г.Б. Елякова Дальневосточного отделения Российской академии наук (ТИБОХ ДВО РАН) Средство пролонгированного анальгетического действия и лекарственный препарат на его основе

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Also Published As

Publication number Publication date
US7906654B2 (en) 2011-03-15
BRPI0715746A2 (pt) 2013-07-16
US20080221188A1 (en) 2008-09-11
US8093402B2 (en) 2012-01-10
NZ575416A (en) 2011-10-28
AU2007282186A1 (en) 2008-02-14
RU2458055C2 (ru) 2012-08-10
ES2533971T3 (es) 2015-04-16
PE20081315A1 (es) 2008-11-08
WO2008018827A1 (en) 2008-02-14
CA2660529A1 (en) 2008-02-14
IL196672A0 (en) 2009-11-18
BRPI0715746B1 (pt) 2020-09-24
SG173360A1 (en) 2011-08-29
CN101792436A (zh) 2010-08-04
MY147649A (en) 2012-12-31
EP2051967A1 (en) 2009-04-29
UY30533A1 (es) 2008-03-31
JP2010500345A (ja) 2010-01-07
RU2009103675A (ru) 2010-09-20
KR20090035701A (ko) 2009-04-10
CL2007002343A1 (es) 2008-04-04
AR062299A1 (es) 2008-10-29
ZA200900961B (en) 2010-07-28
MX2009001496A (es) 2009-02-18
KR101412881B1 (ko) 2014-06-26
UA96764C2 (ru) 2011-12-12
US20110137045A1 (en) 2011-06-09
CA2660529C (en) 2014-10-21
TWI433839B (zh) 2014-04-11
CN101522637A (zh) 2009-09-02
AU2007282186B2 (en) 2011-07-07
EP2051967B1 (en) 2014-12-31
TW200817338A (en) 2008-04-16
CO6150176A2 (es) 2010-04-20
BRPI0715746B8 (pt) 2021-05-25
WO2008018827A8 (en) 2009-02-19
EP2051967A4 (en) 2011-06-29
JP5140077B2 (ja) 2013-02-06

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